A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).
Excerpt | Reference |
"Steroid rosacea is a facial dermatitis clinically resembling acne rosacea." | ( Franco, HL; Weston, WL, 1979) |
"Rosacea is a skin dysfunction affecting a large number of individuals." | ( Sober, AJ, 1992) |
"Acne rosacea is an idiopathic dermatologic disease that frequently produces conjunctival inflammation." | ( Foster, CS; Hoang-Xuan, T; Rice, BA; Rodriguez, A; Zaltas, MM, 1990) |
"Severe forms of rosacea are a new indication for the treatment with 13-cis retinoic acid." | ( Nikolowski, J; Plewig, G, 1980) |
"If rosacea is a clinical possibility, a trial of 1." | ( Arndt, KA; Finley, J; Noe, JM; Rosen, S, 1981) |
"The cause of rosacea is unknown; among other factors a causative role has been postulated for the hair follicle mites Demodex folliculorum and Demodex brevis." | ( Bonnar, E; Eustace, P; Powell, FC, 1993) |
"Acne rosacea is a common skin condition characterized by flushing episodes, erythema, telangiectasia, and recurrent crops of inflammatory papules and pustules that involve the face in a symmetrical distribution." | ( Signore, RJ, 1995) |
"Rosacea is an uncommon disease of the eye and facial skin." | ( Lim, AS; Low, CH; Ng, PH; Yeoh, RL, 1996) |
"Rosacea is a common dermatosis with a variety of clinical manifestations." | ( Chen, DM; Crosby, DL, 1997) |
"Rosacea is an age-related disorder of the central portion of the facial skin whose peak onset occurs in persons in their 40s and 50s." | ( Litt, JZ, 1997) |
"Rosacea is a chronic skin disease that requires long-term therapy." | ( Aly, R; Baker, MO; Bayles, C; Coleman, E; Czernielewski, JM; Dahl, MV; Herndon, JH; Katz, HI; Krueger, GG; Millikan, LE; Odom, RB; Parker, F; Patrignelli, R; Reusser, B; Tuley, MR; Weidner, M; Wolf, JE, 1998) |
"Rosacea is a common condition of unknown etiology usually accompanied by gastrointestinal symptoms and favorably responding to the treatment with antibiotics." | ( Bielański, W; Karczewska, E; Konturek, SJ; Pytko-Polonczyk, J; Sliwowski, Z; Szlachcic, A, 1999) |
"Acne rosacea is a common dermatologic condition which is usually diagnosed by its clinical presentation." | ( Rollins, SD; Sheets, P, 2000) |
"Rosacea is a chronic, cutaneous vascular disorder that affects approximately 13 million Americans." | ( Cuevas, T, 2001) |
"Rosacea is a common dermatosis affecting the central portion of the face." | ( Feldman, SR; Fleischer, AB; Gupta, AK; Hollar, CB, 2001) |
"Rosacea is an inflammatory disease of the face and eyes." | ( Webster, GF, 2001) |
"Rosacea is relatively common, typically occurring in individuals of Northern European and Celtic origin between 30 and 50 years of age." | ( Chaudhry, M; Gupta, AK, 2002) |
"Acne rosacea is a dermatosis with unknown etiology." | ( Atahan, C; Cağlar, K; Erbaş, D; Erel, A; Gürer, MA, 2002) |
"Rosacea is a common, chronic dermatosis for which safe and effective new treatment options are needed." | ( Graupe, K; Thiboutot, D; Thieroff-Ekerdt, R, 2003) |
"Rosacea is a very common facial dermatosis." | ( Del Rosso, JQ, 2004) |
"Granulomatous rosacea is a variant of rosacea that may present similar to other granulomatous diseases." | ( Khachemoune, A; Khokhar, O, 2004) |
"Rosacea is a common, chronic dermatosis that requires long-term therapy." | ( Altinyazar, HC; Eştürk, E; Koca, R; Tekin, NS, 2005) |
"Because rosacea is a chronic condition, pharmacologic maintenance therapy is necessary to maintain remission." | ( Wolf, JE, 2005) |
"Rosacea is a common, chronic facial dermatosis that may present in varying manners." | ( Mackley, CL; Thiboutot, DM, 2005) |
"Rosacea is a chronic facial dermatosis with a progressive course, which is characterized by the presence of erythema, papules, pustules, telangiectasias and sebaceous gland hyperplasia." | ( Gebicki, J; Sysa-Jedrzejowska, A; Wieczorkowska, M; Wozniacka, A, 2005) |
"Since rosacea is a chronic disease and many patients find prescription therapies unsatisfactory, they frequently turn to herbal ingredients for relief of their persistent facial redness." | ( Wu, J, 2006) |
"Rosacea is an inflammatory dermatologic disorder characterized by the presence of facial erythema, visible blood vessels, papules, and pustules." | ( Arsonnaud, S; Kerrouche, N; Wolf, JE, 2006) |
"Rosacea is a common, recurrent, inflammatory dermatologic disorder characterized by the presence of facial erythema, visible blood vessels, papules, and pustules." | ( Beutner, KR; Calvarese, B; Lemke, S, 2006) |
"Rosacea is a common chronic dermatosis that often is characterized by the presence of facial erythema, visible blood vessels, papules, and pustules." | ( Basu, S; Dow, G, 2006) |
"Rosacea is a skin problem not uncommonly encountered world-wide." | ( Al-Salman, HN; Najim, RA; Sharquie, KE, 2006) |
"Rosacea is a common chronic skin and ocular condition." | ( Gover, MD; Graber, M; Gupta, AK; Hollis, S; van Zuuren, EJ, 2007) |
"Acne rosacea is a chronic skin disorder that requires long-term therapy." | ( Fernandez-Obregon, A; Patton, DL, 2007) |
"Rosacea is a common and chronic disorder characterized by flushing, erythema, papules, pustules, and telangiectasia on the central part of the face." | ( Baltas, E; Czernielewski, J; Laquieze, S, 2007) |
"Rosacea is an extremely common chronic dermatosis affecting an estimated 14 million Americans." | ( Balkrishnan, R; Conde, JF; Feldman, SR; Fleischer, AB; Yelverton, CB, 2007) |
"Many patients with rosacea are unable to tolerate extended treatment periods with topical agents because of the unusually high skin sensitivity that often accompanies rosacea." | ( Kormeili, T; Kricorian, GJ; McCullough, JL; Weinstein, GD; Wu, JJ, 2007) |
"Rosacea is a common disease that often has a chronic intermittent course despite current treatment; therefore, additional treatment options are desirable." | ( Bryld, LE; Jemec, GB, 2007) |
"Rosacea is a very common skin disorder in the clinical practice that primarily affects the convex areas of the face." | ( Basto, AS; Pereira, TM; Vieira, AP, 2008) |
"Rosacea is a common inflammatory disorder of the skin." | ( Akhyani, M; Ehsani, AH; Ghiasi, M; Jafari, AK, 2008) |
"Rosacea is a common inflammatory skin disorder for which the pathogenesis is unclear." | ( Eksioglu, HM; Izol Serel, B; Karabulut, AA, 2008) |
"Steroid-induced rosacea is a relatively common dermatosis that is caused by the prolonged application of topical steroid to the face." | ( Lee, DH; Li, K; Suh, DH, 2008) |
"Rosacea is a chronic, inflammatory skin disorder characterized by remissions and relapses." | ( Aslan, E; Ergül, G; Gönül, M; Gül, U; Kiliç, A; Koçak, O; Kulaçoğlu, S, 2008) |
"Rosacea is a facial dermatosis that may present as flushing, erythema, telangiectases, papules, pustules and phyma." | ( Gatti, TR; Kakihara, CT; Pires, MC; Tebcherani, AJ; Vidigal, MR, 2008) |
"Rosacea is a disease of complex pathogenesis and variable response to various therapeutic methods." | ( Abdel Gawad, EH; Al Mokadem, S; El Harras, MA; Gomaa, SM; Mostafa, FF; Nassar, AA, 2009) |
"Acne rosacea is a chronic cutaneous disorder affecting as many as 14 million Americans." | ( Goldstein, JA; Gurge, RM; Trumbore, MW, 2009) |
"Rosacea is a common, often overlooked, chronic facial dermatosis characterized by intermittent periods of exacerbation and remission." | ( Korting, HC; Schöllmann, C, 2009) |
"Rosacea is a common inflammatory condition of the facial skin of unknown etiology, which frequently occurs in combination with gastrointestinal disorders." | ( Whitehead, J, 2009) |
"Rosacea is one of the most common dermatoses of adults." | ( Lehmann, P; Sobottka, A, 2009) |
"Rosacea is a common chronic inflammatory disease of the skin and is associated with a number of etiological causes and inciting factors." | ( Berk, T; Scheinfeld, N, 2010) |
"Rosacea is a common, chronic, cutaneous disorder presenting with recurrent episodes of facial flushing, erythema, papules, pustules and telangiectasias." | ( Drago, F; Gallo, R; Paolino, S; Parodi, A, 2010) |
"Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually." | ( Bruce, S; Del Rosso, JQ; Jarratt, M; Menter, A; Staedtler, G, 2010) |
"Rosacea is one of the most common chronic dermatological diseases." | ( Kárpáti, S; Preisz, K, 2010) |
"Rosacea is a common skin disease that manifests unique inflammatory responses to normal environmental stimuli." | ( Borkowski, AW; Cogen, AL; Gallo, RL; Kanada, K; Macleod, DT; Morizane, S; Nakatsuji, T; Yamasaki, K, 2011) |
"Rosacea is a chronic dermatosis that is usually confined to the face." | ( Cho, SB; Kim, TG; Lee, JH; Lee, SJ; Oh, SH; Roh, HJ, 2011) |
"Rosacea is a prevalent inflammatory skin disorder that affects approximately 16 million individuals in the United States." | ( Del Rosso, JQ, 2010) |
"Rosacea is a common disfiguring skin disease of primarily Caucasians characterized by central erythema of the face, with telangiectatic blood vessels, papules and pustules, and can produce skin thickening, especially on the nose of men, creating rhinophyma." | ( Argyle, B; Kennedy, TP; Krueger, G; McCoard, L; Prestwich, GD; Rao, NV; Rusho, WJ; Xu, X; Zhang, J, 2011) |
"Rosacea is a common chronic skin condition affecting the face, characterised by flushing, redness, pimples, pustules, and dilated blood vessels." | ( Carter, B; Fedorowicz, Z; Graber, MA; Kramer, S; van Zuuren, EJ, 2011) |
"Rosacea is a common chronic cutaneous disorder that primarily occurs on the convex surfaces of the central face and is often characterized by exacerbations and remissions." | ( Choi, EH; Kim, JH; Oh, YS, 2011) |
"Rosacea is a chronic facial inflammatory disease." | ( Webster, GF, 2011) |
"Rosacea is a chronic multifactorial vascular skin disorder that affects about 10 percent of the general population." | ( Jelvehgari, M; Montazam, H, 2011) |
"Childhood ocular rosacea is not rare, but is often misdiagnosed." | ( Aitali, F; Boralevi, F; Chamaillard, M; Colin, J; Léauté-Labrèze, C; Léoni, S; Marques da Costa, C; Mesplié, N; Mortemousque, B; Taïeb, A, 2011) |
"Rosacea is a common inflammatory skin disorder; the pathogenesis is unclear." | ( Chin, HW; Kim, BS; Kim, GW; Kim, HS; Kim, MB; Kim, SH; Ko, HC; Park, HJ, 2011) |
"Rosacea is a chronic skin disorder, characterized by persistent painful facial flushing and often accompanied by papules and pustules." | ( Drummond, PD; Su, D, 2012) |
"Erythema of rosacea is thought to result from abnormal cutaneous vasomotor activity." | ( Fowler, J; Jarratt, M; Leoni, M; Liu, Y; Meadows, K; Moore, A; Pollack, A; Steinhoff, M, 2012) |
" Rosacea is a chronic inflammatory skin disease affecting mostly facial skin." | ( Abril, E; Berardesca, E; Caserini, M; Guglielmini, G; Iorizzo, M; Palmieri, R; Piérard, GE, 2012) |
"Papulopustular acne rosacea is a chronic inflammatory condition which can be difficult to treat." | ( Alora-Palli, M; Amir, O; Chang, AL; Chang, TC; Cheng, C; Chung, CM; Kimball, AB; Lima, XT, 2012) |
"Rosacea is a common dermatosis that can involve the bald area of the scalp." | ( Cribier, B; Kanter, P; Lipsker, D; Mohr, M, 2012) |
"Rosacea is a common chronic skin disorder that has significant impact on the self-esteem and quality of life of affected individuals." | ( Fallen, RS; Gooderham, M, 2012) |
"Rosacea is a common, chronic, and poorly understood dermatological condition characterized by an inflammatory component composed of papules and pustules and a vascular component composed of flushing and erythema." | ( Freeman, SA; Moon, SD; Spencer, JM, 2012) |
"Rosacea is a chronic skin disease of unknown etiology, affecting the central areas of the face skin (cheeks, chin, nose, forehead) and is characterized by periods of remission and exacerbation." | ( Katsitadze, A; Tsiskarishvili, NV; Tsiskarishvili, Ts, 2013) |
"Rosacea is one of the most commonly occurring dermatoses treated by dermatologists." | ( Jackson, JM; Kircik, LH; Lorenz, DJ, 2013) |
"Granulomatous rosacea is an uncommon variant of rosacea." | ( Ehmann, LM; Homey, B; Meller, S, 2013) |
"Rosacea is a common chronic skin condition affecting the face." | ( Balta, I; Dikilitaş, MC; Ekiz, O; Ozuğuz, P; Rifaioğlu, EN; Sen, BB, 2014) |
"Ophthalmic rosacea is treated topically as well as with tetracyclines or macrolides." | ( Belge, K; Schaller, M, 2013) |
"Rosacea is a chronic cutaneous disorder characterized by flushing, erythema, telangiectasia, edema, papules, and pustules." | ( Powell, CR; Schlesinger, TE, 2013) |
"Acne rosacea is a common dermatological conditions associated with blepharitis." | ( Bonini, S; Di Zazzo, A; Dianzani, C; Lambiase, A; Mantelli, F; Sacchetti, M, 2013) |
"Rosacea is a common skin disorder with multiple symptoms." | ( Layton, A; Thiboutot, D, 2013) |
"Rosacea is a chronic inflammatory condition that affects the skin of the face and the eyes." | ( Holland, A; Jakubowicz, O; Jarmuda, S; Kavanagh, K; McMahon, F; O'Reilly, N; Szkaradkiewicz, A; Żaba, R, 2014) |
"Rosacea is a common chronic inflammatory skin disease that primarily affects facial skin." | ( Draelos, ZD; Elewski, B; Havlickova, B; Staedtler, G, 2013) |
"Rosacea is a common, chronic, and inflammatory skin disease." | ( Bribeche, MR; Fedotov, VP; Gladichev, VV; Kolitcheva, NL; Pukhalskaya, DM, 2015) |
"Rosacea is a chronic inflammatory dermatologic condition that can often be disfiguring with significant negative impact on patients' quality of life." | ( Moore, AY; Tong, LX, 2014) |
"Rosacea is a chronic inflammatory disease that predominantly affects facial skin in light-skinned individuals and can be divided into 4 subtypes." | ( Goldenberg, G; Mansouri, Y, 2014) |
"Rosacea is a chronic inflammatory skin condition that negatively impacts patients' quality of life." | ( Feldman, SR; Moustafa, FA; Sandoval, LF, 2014) |
"Rosacea is a chronic inflammatory disease with a complex pathophysiology that manifests with central facial redness with or without papulopustular lesions." | ( Belasco, KT; Cadena, MJ; Friedrichs, A; Hinek, A; Hong, HC; Hougier, F; Jackson, JM; Johnson, SM; Kerdel, FA; Palceski, D; Tanghetti, EA, 2015) |
"Rosacea is a common chronic skin condition affecting the face, characterised by flushing, redness, pimples, pustules and dilated blood vessels." | ( Carter, B; Charland, L; Fedorowicz, Z; van der Linden, MM; van Zuuren, EJ, 2015) |
"The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status." | ( Ali, ST; Alinia, H; Feldman, SR, 2015) |
"Rosacea is a common chronic inflammatory cutaneous disease of unknown etiology, characterized by remissions and exacerbations, presenting with centrofacial erythema and telangiectasias." | ( Mokos, ZB; Paštar, Z; Rezaković, S, 2015) |
"Facial flushing in rosacea is often induced by trigger events." | ( Demidova, O; Jurovcik, AJ; Mann, S; Metzler-Wilson, K; Sammons, DL; Toma, K; Wilson, TE, 2015) |
"Rosacea is a chronic relapsing skin disorder primarily affecting the face." | ( Draelos, ZD; Elewski, BE; Harper, JC; Nkulikiyinka, R; Sand, M; Shakery, K; Staedtler, G, 2015) |
"Rosacea is a chronic facial skin condition of unknown cause." | ( Muncie, HL; Oge', LK; Phillips-Savoy, AR, 2015) |
"Rosacea is a common chronic inflammatory disorder that affects approximately 16 million Americans." | ( Draelos, ZD; Gold, LM, 2015) |
"Rosacea is an inflammatory skin disease." | ( Chan, AT; Cho, E; Khalili, H; Li, WQ; Qureshi, AA; Wu, S, 2016) |
"Personal history of rosacea is associated with an increased risk of only CD." | ( Chan, AT; Cho, E; Khalili, H; Li, WQ; Qureshi, AA; Wu, S, 2016) |
"Rosacea is a chronic inflammatory condition that predominantly affects the skin of the face." | ( Banville, N; Bergin, DA; Kavanagh, K; McMahon, F; Paulie, S; Reeves, E; Smedman, C, 2016) |
"Rosacea is a chronic facial skin disease that mainly occurs in people aged over 30 years." | ( , 2015) |
"Rosacea is a common chronic skin condition that displays a broad diversity of clinical manifestations." | ( Schauber, J; Schmelz, M; Steinhoff, M, 2016) |
"Rosacea is a chronic inflammatory facial skin disease with psychosocial impact." | ( Anselin, E; Chidiack, H; Chosidow, O; Cribier, B; Dréno, B; Sbidian, E; Vicaut, É, 2016) |
"The pathogenesis of rosacea is unclear, but increased matrix metalloproteinase target tissue activity appears to play an important role." | ( Egeberg, A; Gislason, GH; Hansen, PR; Thyssen, JP, 2016) |
"Rosacea is a chronic facial inflammatory dermatosis characterized by background facial erythema and flushing and may be accompanied by inflammatory papules and pustules, cutaneous fibrosis and hyperplasia known as phyma, and ocular involvement." | ( Asai, Y; Baibergenova, A; Barankin, B; Cochrane, CL; Humphrey, S; Lynde, CW; Marcoux, D; Poulin, Y; Rivers, JK; Sapijaszko, M; Sibbald, RG; Tan, J; Toole, J; Ulmer, M; Zip, C, 2016) |
"Rosacea is a chronic disease with a profound impact on quality of life." | ( Fedorowicz, Z; van Zuuren, EJ, 2016) |
"Papulopustular rosacea is a chronic skin disease involving central facial erythema in combination with papules and pustules." | ( Bertranou, E; Dansk, V; Feldman, SR; Stein Gold, L; Taieb, A, 2016) |
"Rosacea is an inflammatory condition of the skin, primarily affecting the central convexities of the face." | ( Helfrich, YR; Maier, LM, 2016) |
"Acne and rosacea are common inflammatory processes historically classified in the same disease category, but evolving understanding of their disparate pathophysiology and exacerbating factors have generated an enormous armamentarium of therapeutic possibilities." | ( Rosamilia, LL, 2016) |
"Acne and rosacea are common conditions seen every day by dermatologists." | ( Keri, J, 2016) |
"Rosacea is a common, chronic inflammatory skin disease that can present with a variety of signs and symptoms." | ( Hacini-Rachinel, F; Schäfer, G; Steinhoff, M; Vocanson, M; Voegel, JJ, 2016) |
"Rosacea is a chronic inflammatory disorder that affects up to 10% of the population." | ( Rademaker, M, 2018) |
"Rosacea is a chronic skin disorder associated with flushing, erythema, dryness, burning and stinging, and inflammatory papules and pustules." | ( Fowler, JF, 2016) |
"Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics." | ( Detmar, M; Di Nardo, A; Docherty, JR; Holmes, A; Lorton, D; Schäfer, G; Steinhoff, M, 2016) |
"Rosacea is a chronic, multifactorial, dermatological condition." | ( Jebraeili, R; Mansouri, P; Naraghi, Z; Rajabi, M; Raoufinejad, K, 2016) |
"Rosacea is a highly prevalent, chronic inflammatory disease." | ( Landa Gundin, N; Mendieta Eckert, M, 2016) |
"Rosacea is a chronic inflammatory disease that can manifest as a spectrum of symptoms including erythema, inflammatory lesions, edema, and telangiectasia." | ( Gonser, L; Schaller, M, 2016) |
"Rosacea is a chronic and common cutaneous condition characterised by symptoms of facial flushing and a broad spectrum of clinical signs." | ( Chong, AH; Maor, D, 2017) |
"Rosacea is a major clinical disease with vasodilatation and rash on the centre of the face, and that brimonidine as a vasoconstrictor can act as a remedy for rosacea." | ( Jeong, SW; Jo, H; Kim, J; Kim, M; Park, HJ; Woo, YR, 2017) |
"Granulomatous rosacea is a rare chronic inflammatory skin disease with an unknown origin." | ( Kelati, A; Mernissi, FZ, 2017) |
"Rosacea is a chronic skin condition characterized by transient and persistent erythema of the central face." | ( Feldman, SR; Patel, NU; Shukla, S; Zaki, J, 2017) |
"Rosacea is a chronic inflammatory skin disease of the face." | ( Carlavan, I; Jarratt, M; Martel, P; Weiss, J, 2017) |
"Rosacea is the most common inflammatory skin disease." | ( Calpena, AC; Espina, M; Espinoza, LC; Fábrega, MJ; García, ML; Rodríguez-Lagunas, MJ; Silva-Abreu, M, 2017) |
"Rosacea is characterized by erythema on face, especially erythema and linear telangiectasia on the nose." | ( Cho, EB; Kim, KH; Kim, KJ; Kwon, WJ; Park, BW; Park, EJ, 2018) |
"Rosacea is a common chronic facial skin disease." | ( Chan, R; Cheong, KW; Lai, YC; Yew, YW, 2018) |
"Rosacea is more common among certain racial groups such as Chinese, Caucasian, and other races." | ( Chan, R; Cheong, KW; Lai, YC; Yew, YW, 2018) |
"Papulopustular rosacea is characterized by papules and pustules in the central facial region." | ( Alinia, H; Feldman, SR; Fleischer, A; McGregor, SP; Snyder, A; Tuchayi, SM, 2018) |
"Rosacea is a chronic dermatologic condition with limited treatment options, particularly for persistent erythema." | ( Ahluwalia, G; Baumann, L; Berk, DR; Goldberg, DJ; Kaufman, J; Lain, E; Stein Gold, L; Tanghetti, EA; Weng, E, 2018) |
"Rosacea is a chronic dermatologic condition with limited treatment options." | ( Ahluwalia, G; Berk, DR; Dover, JS; DuBois, J; Jones, TM; Weiss, RA, 2018) |
"Rosacea is a chronic and recurrent disease with a variety of cutaneous manifestations." | ( Feldman, SR; Sahni, DR; Taylor, SL, 2018) |
"Acne rosacea is a type of chronic dermatosis with the characteristics of erubescence, angiotelectasis and pustule formation." | ( Chen, X; Hu, Y; Li, T; Wang, G; Wang, H; Yu, A; Zeng, Q; Zhang, H, 2018) |
"Rosacea is a chronic inflammatory disease with facial erythema and papulopustules." | ( Angesjö, E; Berg, M; Dunér, K; Mobacken, H; Svensson, M; Synnerstad, I, 2018) |
"Rosacea is a common inflammatory skin condition that impacts a large portion of fair-skinned populations." | ( Cervantes, J; Darwin, E; Lev-Tov, H, 2018) |
"Rosacea is a common chronic cutaneous disorder which is characterized by flushing, erythema, papulopustules and telangiectasia." | ( Fan, L; Hamblin, MR; Lan, T; Yin, R, 2018) |
"Rosacea is an irritating disease that affects patients' health and life quality." | ( Chen, Y; Gao, Y; He, J; Lin, W; Shi, G; Zhou, S, 2018) |
"Rosacea is a chronic inflammatory skin disease." | ( Bertino, B; Blanchet-Réthoré, S; Bogouch, A; Bourdès, V; Dugaret, AS; Gamboa, B; Méhul, B; Nonne, C; Petit, L; Piwnica, D; Reynier, P; Roquet, M; Thibaut de Ménonville, S; Vial, E; Voegel, JJ; Zugaj, D, 2018) |
"Rosacea is a chronic inflammatory cutaneous disease characterized by immune system anomalies and vascular hyperreactivity." | ( Deng, Z; Li, J; Li, Y; Tang, Y; Wang, B; Xie, H; Xu, S; Yuan, X; Zhang, Y; Zhao, Z; Zuo, Z, 2019) |
"Rosacea is a common chronic facial dermatosis." | ( Arents, BWM; Carter, B; Charland, L; Fedorowicz, Z; Tan, J; van der Linden, MMD; van Zuuren, EJ, 2019) |
"Rosacea is a frequently seen chronic disease." | ( Çifci, N, 2019) |
"Rosacea is a prevalent skin condition dependent on the individual genetic profile." | ( Bohr, A; Colombo, S; Harmankaya, N; Water, JJ, 2019) |
"Rosacea is a chronic inflammatory skin condition whose etiology has been linked to mast cells and the antimicrobial peptide cathelicidin LL-37." | ( Choi, JE; Di Nardo, A; Wang, Z; Werbel, T; Wu, CC; Yaksh, TL, 2019) |
"Background: Rosacea is characterized by irritation associated with erythema, telangiectasias and papules/pustules." | ( Draelos, ZD; Gunt, H; Levy, SB, 2019) |
"Rosacea is a chronic inflammatory skin disorder of uncertain etiology." | ( Chen, M; Chen, Z; Deng, Z; Li, J; Liu, T; Peng, Q; Sha, K; Wang, B; Xiao, W; Xie, H; Xu, S; Zhang, Y, 2019) |
"Rosacea is a chronic skin condition that typically affects the face and it results in redness and inflammation." | ( Asgharian, R; Azizian, Z; Ebneyamin, E; Mansouri, P; Qomi, M; Rajabi, M, 2020) |
"Rosacea is a chronic dermatosis which affects negatively patients' quality of life (QoL)." | ( Husein-ElAhmed, H; Steinhoff, M, 2020) |
"Papulopustular rosacea is characterized by chronic facial erythema and inflammatory facial lesions." | ( Dhawan, S; Draelos, ZD; Graber, E; Lee, MS; Magrath, GN; Salman, M; Webster, G, 2020) |
"Rosacea is a chronic inflammatory disease in face." | ( Deng, Z; Huang, Y; Li, J; Liu, F; Tang, Y; Wang, B; Yuan, X; Zhang, Y; Zhao, Z, 2020) |
"Rosacea is an inflammatory skin disease with a chronic course." | ( Karaaslan, E; Karaosmanoglu, N; Ozdemir Cetinkaya, P, 2020) |
"Rosacea is a common chronic inflammatory skin disease that the pathogenesis is not fully understood." | ( Turkmen, D, 2020) |
"Rosacea is one of the most common conditions affecting the ocular surface." | ( Caughlin, B; Djalilian, AR; Jabbehdari, S; Memar, OM, 2021) |
"Rosacea is a complex inflammatory condition involving the pilosebaceous unit." | ( Caughlin, B; Djalilian, AR; Jabbehdari, S; Memar, OM, 2021) |
"Rosacea is a common inflammatory skin disorder with centrofacial erythema, flushing, telangiectasia, papules/pustules, and possible ocular or phymatous manifestation." | ( Cappello, C; Clanner-Engelshofen, BM; Guertler, A; Jøntvedt, NM; Reinholz, M; Sager, A, 2020) |
"Rosacea is a very common, chronic inflammatory disease characterized by flushing, erythema and inflammatory lesions." | ( Dall'Oglio, F; Micali, G; Milani, M; Puviani, M, 2021) |
"Phymatous rosacea is a rare and severe form of rosacea that manifests as disfiguring soft-tissue hypertrophy and sebaceous gland hyperplasia and fibrosis." | ( Bittar, JM; Ditre, CM; Kovach, SJ, 2020) |
"Rosacea is a chronic skin condition characterized by primary and secondary manifestations affecting the centrofacial skin." | ( Baldwin, H; Harper, JC; Stein Gold, L, 2020) |
"Rosacea is an evolving condition; care should take into account all clinical signs and symptoms of rosacea that are present in an individual patient, understanding that symptoms may change over time, and utilize combination therapy when applicable to target all rosacea symptoms." | ( Baldwin, H; Harper, JC; Stein Gold, L, 2020) |
"Rosacea is a common skin disease that is troublesome for both the patients and the dermatologists." | ( Rusina, T; Snarskaya, E, 2021) |
"Rosacea is a facial chronic inflammatory skin disease with immune and vascular system dysfunction." | ( Hu, L; Jiang, P; Liu, W; Liu, Y; Liu, Z; Wang, X; Xu, Y; Yin, Z; Zhang, J, 2021) |
"The pathogenesis of rosacea is incompletely understood." | ( Ashina, M; Christensen, CE; Coskun, H; Egeberg, A; Ghanizada, H; Thyssen, JP; Wienholtz, NKF; Zhang, DG, 2021) |
"Inflammatory rosacea is clinically characterized by persistent erythema and inflammatory lesions." | ( Dall'Oglio, F; Lacarrubba, F; Micali, G, 2021) |
"Rosacea is a common cutaneous condition affecting predominantly the face." | ( Al-Niaimi, F; Ali, FR; Searle, T, 2021) |
"Rosacea is a chronic, relapsing inflammatory skin disease featured by abnormal activation of immune responses, vascular dysfunction and prominent permeability barrier alterations." | ( Chen, M; Deng, Z; Li, J; Liu, T; Peng, Q; Sha, K; Wang, B; Xiao, W; Xie, H; Xu, S; Zhang, Y, 2021) |
"Rosacea is a chronic inflammatory skin disease characterized by immune response-dependent erythema and pustules." | ( Cho, HJ; Hwang, I; Kim, TG; Lee, E; Ryu, JH; Yoon, SH; Yu, JW, 2021) |
"Rosacea is a common inflammatory facial skin condition affecting the adult population." | ( Galili, E; Gupta, AK; Kassem, R; Quinlan, EM; Sharon, N; Shemer, A, 2021) |
"Rosacea is a chronic inflammatory disease mainly with skin or ocular manifestations." | ( Fang, R; Sun, Q; Tang, K; Wang, Y; Yang, L; Zhang, D; Zhang, H, 2022) |
"Acne and rosacea are common inflammatory skin conditions present in numerous racial and ethnic groups." | ( Maruthappu, T; Taylor, M, 2022) |
"Rosacea is a common chronic inflammatory disease that affects the middle of the face." | ( Deng, Z; Li, J; Li, Y; Wang, Y; Xie, H; Xu, S; Yang, L; Zhang, Y, 2021) |
"Rosacea is a complex disease involving many different mechanisms and with numerous possible treatments, but there are still some important unmet needs with regard to optimal care." | ( Cribier, B, 2022) |
"Rosacea is significantly associated with dementia, particularly Alzheimer's disease (AD)." | ( Deng, Z; Li, J; Li, Y; Wang, Y; Xie, H; Xu, S; Yan, S; Yang, X; Zhang, H; Zhang, Y, 2021) |
"Rosacea is a chronic cutaneous disorder affecting primarily the face, characterized by erythema, transient or persistent, telangiectasia, and inflammatory lesions including papulo-pustules and swelling." | ( Galadari, H; Goldust, M; Goren, A; Grabbe, S; Kassir, M; Kroumpouzos, G; Sharma, A, 2022) |
"Rosacea is a common chronic inflammatory skin disease involving millions of patients worldwide." | ( Chen, M; Deng, Z; Li, J; Liu, T; Sha, K; Xiao, W; Xie, H; Zhao, Z, 2022) |
"Ocular rosacea is a special manifestation of rosacea with unknown etiology." | ( Clanner-Engelshofen, BM; Dietrich, C; French, LE; Guertler, A; Hildebrand, JA; Reinholz, M; Zierl, S, 2022) |
"Rosacea is a chronic inflammatory skin condition of varying severity that can significantly impact patient quality of life." | ( Barbarino, SC; Bucay, VW; Cohen, JL; Gold, MH, 2022) |
"Rosacea is a chronic inflammatory skin disease with a multifactorial etiology." | ( Chung, BY; Chung, EH; Eun, YS; Heo, NH; Kim, HO; Kim, JE; Kim, JY; Lee, SH; Lee, SY; Park, CW; Park, YL; Shin, MJ; Yang, NG, 2022) |
"Initially, rosacea is characterized by recurrent erythema, telangiectasia and flushing." | ( Bernhard, D; Clanner-Engelshofen, BM; Dargatz, S; Flaig, MJ; Gieler, U; Kinberger, M; Klövekorn, W; Kuna, AC; Läuchli, S; Lehmann, P; Nast, A; Pleyer, U; Reinholz, M; Schaller, M; Schöfer, H; Schwennesen, T; Steinhoff, M; Werner, RN; Zierhut, M, 2022) |
"Rosacea is a chronic inflammatory skin disease with a high incidence, and it leads to negative emotions such as inferiority complex, increased psychological pressure, and a greatly reduced quality of life." | ( Peng, C; Yan, F, 2022) |
"Papulopustular rosacea is notoriously a challenge to treat, and treatment options are scarce." | ( Egeberg, A; Ring, HC; Thomsen, SF; Thyssen, JP; Zachariae, C, 2022) |
"Rosacea is a chronic inflammatory skin disorder with unclear etiology." | ( Chen, M; Deng, Z; Li, J; Liu, T; Peng, Q; Sha, K; Xia, J; Xiao, W; Xie, H; Xu, S, 2022) |
"Rosacea is a chronic inflammatory skin disease characterized by facial erythema, papules, pustules, telangiectasia, and flushing." | ( Huang, CZ; Lao, LM; Man, XY; Shen, Y; Sun, YH; Xuan, XY, 2022) |
"Rosacea is likely to be underdiagnosed and undertreated in Japan because of the current lack of consensus guidelines and standardized therapy." | ( Miyachi, Y; Yamasaki, K, 2022) |
"Rosacea is a kind of chronic inflammatory skin disease that usually occurs in the middle of the face." | ( Huang, J; Liu, J; Xie, Y; Zhang, Q, 2022) |
"Rosacea is an inflammatory dermatosis with at least a ten percent prevalence reported among white adults." | ( Andriessen, A; Antelo, D; Cestari, S; Gonzalez, C; McKeever, C; Valencia Hernandez, AL, 2022) |
"Rosacea is a chronic skin disorder characterized by abnormal neurovascular and inflammatory conditions on the central face." | ( Chen, M; Deng, Z; Li, J; Liu, T; Mao, R; Peng, Q; San, X; Wang, Q; Xiao, W; Xie, H; Zhao, Z, 2022) |
"Ocular rosacea is a chronic inflammatory disorder with periods of exacerbation and remission, often underdiagnosed in children." | ( Brémond-Gignac, D; Chiambaretta, F; Doan, S; Navel, V, 2022) |
"Childhood ocular rosacea is potentially sight threatening." | ( Brémond-Gignac, D; Chiambaretta, F; Doan, S; Navel, V, 2022) |
"Rosacea is a chronic and relapsing facial dermatosis that encompasses a wide spectrum of clinical phenotypes (transient/persistent erythema, telangiectasias, papules/pustules, edema, phymatous changes, and ocular symptoms) often with uncomfortable symptoms such as flushing, pain, burning, edema, and dryness." | ( Dall'Oglio, F; Gerbino, C; Micali, G; Nasca, MR, 2022) |
"Rosacea is a chronic inflammatory skin disease with immunological dysfunction." | ( Chen, L; Gao, X; Shi, D; Sun, Y; Wang, J; Wang, Y; Wu, Y, 2023) |
"While rosacea is a common dermatologic condition, ocular rosacea is sometimes evident either with cutaneous rosacea or occasionally by itself." | ( Andreas, M; Fabczak-Kubicka, A; Schwartz, RA, 2023) |
"Facial erythema in rosacea is a troublesome embarrassing presentation with limited options of treatment." | ( Abdelhameed, SS; El-Domyati, M; Medhat, W; Nasif, G; Rezk, AF, 2023) |
"Rosacea is a chronic skin disorder involving central facial erythema secondary to vascular instability and cutaneous inflammation." | ( Gold, MH; Ivanic, MG; Javadi, SS; Norden, A; Oulee, A; Wu, JJ, 2023) |
"Ocular rosacea is an underdiagnosed form of rosacea that may occur without typical cutaneous signs of rosacea." | ( Avraham, S; Kashetsky, N; Khaslavsky, S; Mukovozov, I; Starkey, SY, 2023) |
"Rosacea is a common chronic inflammatory skin condition that is often refractory to treatment, with frequent relapses." | ( Choi, YS; Ham, S; Kim, J; Lee, JH; Lee, SG; Lee, YI, 2023) |
"Rosacea is a chronic and inflammatory disease that primarily affects the skin, although more than half of cases also present with ocular symptoms ranging from blepharitis to conjunctivitis and keratitis." | ( Malagón-Liceaga, A; Recillas-Gispert, C; Ruelas-Villavicencio, AL; Ruiz-Quintero, NC, 2023) |