Page last updated: 2024-08-05 10:36:13
pteridines
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ChEBI ID: 26373
Members (14)
| Member | Definition | Role |
|---|---|---|
| 10-propargyl-10-deazaaminopterin | A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. | pralatrexate |
| 4-amino-6,7-diphenyl-3H-pteridine-2-thione | 4-amino-6,7-diphenyl-3H-pteridine-2-thione | |
| 5,6,7,8-tetrahydropteridine | 5,6,7,8-tetrahydropteridine | |
| 6,7-bis(4-aminophenyl)pteridine-2,4-diamine | 6,7-bis(4-aminophenyl)pteridine-2,4-diamine | |
| 6,7-dimethyl-8-ribityllumazine, (d)-isomer | The pteridine that is lumazine substituted with methyl groups at C-6 and -7 and with a 1-D-ribityl group on N-8. | 6,7-dimethyl-8-(1-D-ribityl)lumazine |
| 7-hydroxy-6-methyl-8-(1-d-ribityl)lumazine | A D-ribityl derivative of pteridine that is a potent inhibitor of riboflavin synthetase. | 6-methyl-7-oxo-8-(1-D-ribityl)lumazine (2-hydroxy tautomer); 6-methyl-7-oxo-8-(1-D-ribityl)lumazine (2-oxo tautomer) |
| 7-hydroxy-6-methyl-8-(1-d-ribityl)lumazine | A pteridine that is lumazine substituted by methyl and oxo groups at C-6 and -7 respectively as well as a 1-D-ribityl group on N-8. | 6-methyl-7-oxo-8-(1-D-ribityl)lumazine (2-hydroxy tautomer); 6-methyl-7-oxo-8-(1-D-ribityl)lumazine (2-oxo tautomer) |
| methotrexate | methotrexate | |
| o 129 | A member of the class of pteridines that is pteridine in which the hydrogens at positions 2 and 4 are replaced by amino groups, whilst those at positions 6 and 7 are replaced by isopropyl groups. | 2,4-diamino-6,7-diisopropylpteridine |
| pteridines | pteridine | |
| surugatoxin | Surugatoxin | |
| tg100-115 | 3-[2,4-diamino-7-(3-hydroxyphenyl)-6-pteridinyl]phenol | |
| triamterene | Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema. | triamterene |
| violapterin | A member of the class of pteridines that is pteridine in which the hydrogens at positions 2, 4, and 7 have been replaced by hydroxy groups. | 2,4,7-trihydroxypteridine |
Research
Studies (42,681)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 13,914 (32.60) | 18.7374 |
| 1990's | 7,358 (17.24) | 18.2507 |
| 2000's | 7,784 (18.24) | 29.6817 |
| 2010's | 10,014 (23.46) | 24.3611 |
| 2020's | 3,611 (8.46) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 5,914 (12.90%) | 5.53% |
| Reviews | 4,967 (10.83%) | 6.00% |
| Case Studies | 6,945 (15.14%) | 4.05% |
| Observational | 346 (0.75%) | 0.25% |
| Other | 27,687 (60.37%) | 84.16% |