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orthoquinones

Any quinone in which the carbons of the two carbonyl groups in the quinone system are joined to each other by a single bond.

ChEBI ID: 25622

Members (10)

MemberDefinitionRole
1,5(10)-estradiene-3,4,17-trioneAn o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 4-hydroxyestrone.estra-1,5(10)-diene-3,4,17-trione
acenaphthenequinoneAn orthoquinone that is the 1,2-dioxo derivative of acenaphthene.acenaphthoquinone
aminochrome 1A member of the class of indoledione that is 2,3,5,6-tetrahydro-1H-indole carrying oxo groups at positions 5 and 6; major microspecies at pH 7.3. It is an endogenous compound formed during dopamine oxidation and can induce neurotoxicity under certain aberrant conditions and induce Parkinson-like syndrome.dopaminechrome (keto form)
benzo(a)pyrene-7,8-dioneAn o-quinone resulting from the formal oxidation of both of the hydroxy groups of benzo[a]pyrene-cis-7,8-dihydrodiol. Benzo[a]pyrene-7,8-dione is a metabolite of the widespread carcinogen benzo[a]pyrene.benzo[a]pyrene-7,8-dione
beta-lapachoneA benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.beta-lapachone
cysteine tryptophylquinoneAn L-tryptophan derivative that is L-tryptophan-6,7-dione in which a cysteine unit is attached at position 4 via its side-chain thiol group.cysteine tryptophylquinone
dopachromedopachrome
estra-1(10),4-diene-2,3,17-trioneAn o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 2-hydroxyestrone.estra-1(10),4-diene-2,3,17-trione
phanquinoneAn orthoquinone that is the 5,6-diketo derivative of 4,7-phenanthroline.phanquone
pqq cofactorA pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.pyrroloquinoline quinone

Research

Studies (1,363)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990150 (11.01)18.7374
1990's270 (19.81)18.2507
2000's307 (22.52)29.6817
2010's467 (34.26)24.3611
2020's169 (12.40)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials10 (0.71%)5.53%
Reviews125 (8.90%)6.00%
Case Studies1 (0.07%)4.05%
Observational0 (0.00%)0.25%
Other1,269 (90.32%)84.16%