17alpha-hydroxy-C21-steroid

Any C21-steroid carrying a hydroxy substituent at the 17alpha-position. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure.

ChEBI ID: 138141

Members (3)

Member	Definition	Role
17-alpha-hydroxypregnenolone	A hydroxypregnenolone carrying an alpha-hydroxy group at position 17.	17alpha-hydroxypregnenolone
17-alpha-hydroxyprogesterone	A 17alpha-hydroxy steroid that is the 17alpha-hydroxy derivative of progesterone.	17alpha-hydroxyprogesterone
21-deoxycortisol	A deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency.	21-deoxycortisol

Research

Studies (2,555)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	958 (37.50)	18.7374
1990's	539 (21.10)	18.2507
2000's	515 (20.16)	29.6817
2010's	410 (16.05)	24.3611
2020's	133 (5.21)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	153 (5.35%)	5.53%
Reviews	103 (3.60%)	6.00%
Case Studies	204 (7.13%)	4.05%
Observational	10 (0.35%)	0.25%
Other	2,391 (83.57%)	84.16%