Page last updated: 2024-09-28

Jaundice, Spirochetal

A severe form of LEPTOSPIROSIS, usually caused by LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE and occasionally other serovars. It is transmitted to humans by the rat and is characterized by hemorrhagic and renal symptoms with accompanying JAUNDICE.

Synonyms(4)

Synonym
Leptospirosis, Icterohemorrhagic
Weil Disease
Weil's Disease
Jaundice, Spirochetal

Research Excerpts

Research

Studies (145)

TimeframeStudies, This Condition (%)All Conditions %
pre-199090 (62.07)23.3326
1990's23 (15.86)12.5806
2000's19 (13.10)18.1394
2010's10 (6.90)28.8240
2020's3 (2.07)9.53
DrugIndicatedRelationship StrengthStudiesTrials
quinacrine0low10
chlorine0low10
glycine0low20
taurine0low10
urea0low20
1-anilino-8-naphthalenesulfonate0low10
mercaptoethanol0low10
cimetidine0low10
ciprofloxacin0low10
gentamicin0low20
ofloxacin0low10
prednisolone0low40
thyroxine0low10
spironolactone0low10
prednisone0low30
penicillin g0medium121
chloramphenicol0low20
cephalothin0low10
methionine0low10
ampicillin0low50
mannitol0low10
tryptophan0low10
isoleucine0low10
phencyclidine0low10
methylprednisolone0low30
penicillanic acid0low10
n-vinyl-2-pyrrolidinone0low10
diphenylamine0low10
acetylcysteine0low10
erythromycin0low20
digoxigenin0low10
streptomycin0low70
dihydrostreptomycin sulfate0low20
ethionine0low20
cetylpyridinium chloride anhydrous0low10
4-methoxyamphetamine0low10
amoxicillin0low10
piperacillin0low10
cephalosporin c0low10
triazoles0low10
voriconazole0low10
clarithromycin0low10
fibrinogen0low20
glycidyl nitrate0low10
tazobactam0low10
aminopterin0low10
cortisone0low20
fibrin0low10
riboflavin0low10
enclomiphene0low10
thiobarbituric acid0low10
bilirubin0low140
vitamin k semiquinone radical0low10
6-ketoprostaglandin f1 alpha0low10
amphotericin b0low10
thromboxane b20low10
deamino arginine vasopressin0low10
phosphorus0low10
cefotaxime0low10
amoxicillin-potassium clavulanate combination0low20
acid phosphatase0low20
oligonucleotides0low10
ro13-99040low50
glycolipids0low10
ascorbic acid0low10
tetracycline0low60
chlortetracycline0low90
oxytetracycline, anhydrous0low10
methacycline0low10
thymic factor, circulating0low10
agar0low10
exudates0low20
clozapine0low10
eye0low30

Protein Targets (783)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase3003
thioredoxin reductase100010
USP1 protein, partial100010
TDP1 protein170017
vitamin D3 receptor isoform VDRA9009
importin subunit beta-1 isoform 14004
flap endonuclease 18008
serine/threonine-protein kinase PLK15005
snurportin-14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
GTP-binding nuclear protein Ran isoform 12002
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)110011
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
geminin170017
DNA polymerase kappa isoform 1110011
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0202
Transthyretin0113
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0112
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20112
Choline O-acetyltransferase0101
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G3003
Fatty acid-binding protein 50011
Fatty acid-binding protein 50011
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
5-hydroxytryptamine receptor 2C0315
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 1A0415
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 1D0314
5-hydroxytryptamine receptor 1F0314
5-hydroxytryptamine receptor 2B0325
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0415
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0112
Solute carrier organic anion transporter family member 2A10002
Chain A, 2-oxoglutarate Oxygenase8008
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
acetylcholinesterase7007
dopamine D1 receptor3003
15-lipoxygenase, partial2002
pregnane X receptor5005
phosphopantetheinyl transferase8008
RAR-related orphan receptor gamma130013
NFKB1 protein, partial2002
Microtubule-associated protein tau7007
Thrombopoietin1001
AR protein210021
regulator of G-protein signaling 45005
glucocorticoid receptor [Homo sapiens]170017
retinoic acid nuclear receptor alpha variant 1160016
retinoid X nuclear receptor alpha120012
farnesoid X nuclear receptor9009
estrogen nuclear receptor alpha240024
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2150015
Bloom syndrome protein isoform 14004
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a5005
thyroid hormone receptor beta isoform 2140014
heat shock protein beta-17007
peripheral myelin protein 226006
survival motor neuron protein isoform d5005
muscarinic acetylcholine receptor M14004
Histone deacetylase 30101
Solute carrier family 22 member 60606
Histone deacetylase 40101
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-27007
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase5005
hypoxia-inducible factor 1 alpha subunit7007
SMAD family member 26006
SMAD family member 36006
nuclear receptor subfamily 1, group I, member 3110011
estrogen-related nuclear receptor alpha200020
pregnane X nuclear receptor150015
peroxisome proliferator-activated receptor delta100010
peroxisome proliferator activated receptor gamma9009
activating transcription factor 68008
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
Histone H2A.x7007
nuclear factor erythroid 2-related factor 2 isoform 1170017
Dihydrofolate reductase0404
Dihydrofolate reductase0203
Dihydrofolate reductase0102
Cellular tumor antigen p53130013
Dihydrofolate reductase0101
Folylpolyglutamate synthase, mitochondrial0102
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, Beta-lactamase6006
Beta-lactamase 0105
Beta-lactamase 0106
Beta-lactamase 0005
Beta-lactamase 0106
apical membrane antigen 1, AMA14004
Beta-lactamase 0004
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012012
Bile salt export pump0303
Bile salt export pump018018
Beta-lactamase SHV-10106
Beta-lactamase SHV-10207
Cytochrome P450 2C9 0809
Beta-lactamase0106
Kappa-type opioid receptor0005
Solute carrier family 15 member 10707
Solute carrier family 15 member 10202
Cytochrome P450 2J20506
B2 metallo-beta-lactamase 0004
Solute carrier family 15 member 20505
Beta-lactamase 0106
Beta-lactamase 0005
Solute carrier family 15 member 20505
Beta-lactamase 0106
Beta-lactamase 0005
Canalicular multispecific organic anion transporter 1011011
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, Cruzipain5005
interleukin 83003
GLS protein7007
tumor necrosis factor2002
lamin isoform A-delta10110011
Cytochrome P450 1A20202
Cytochrome P450 3A40809
Cytochrome P450 2D60405
Cytochrome P450 2C190405
Nuclear receptor ROR-gamma2002
Potassium voltage-gated channel subfamily H member 209010
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0206
GLI family zinc finger 3190019
Beta-lactamase 0105
Beta-lactamase 0106
Metallo-beta-lactamase type 20005
Metallo-beta-lactamase VIM-11 0004
Metallo-beta-lactamase VIM-20004
Beta-lactamase 0005
Metallo-beta-lactamase0004
Beta-lactamase 0105
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
chromobox protein homolog 19009
DNA polymerase beta3003
Carbonic anhydrase 10203
Carbonic anhydrase 20203
60 kDa heat shock protein, mitochondrial0303
Beta-lactamase OXA-70002
Spike glycoprotein6006
10 kDa heat shock protein, mitochondrial0303
Angiopoietin-1 receptor0011
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130005
Efflux transporter 0003
Beta-lactamase 0105
Beta-lactamase Toho-10004
Beta-lactamase 0003
Class D beta-lactamase0104
60 kDa chaperonin 0303
Metallo-beta-lactamase0003
Beta-lactamase 0105
Beta-lactamase 0002
10 kDa chaperonin 0303
Metallo-b-lactamase 0006
Carbapenem-hydrolyzing beta-lactamase KPC0207
Histamine H3 receptor0004
Beta-lactamase class B VIM-2 0006
Beta-lactamase VIM-1 0005
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase5005
cytochrome P450 family 3 subfamily A polypeptide 49009
IDH18008
nuclear factor erythroid 2-related factor 2 isoform 26006
lethal(3)malignant brain tumor-like protein 1 isoform I2002
lethal factor (plasmid)5005
Polyphenol oxidase 20202
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0617
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
aldehyde dehydrogenase 1 family, member A1100010
caspase-1 isoform alpha precursor2002
Caspase-72002
Inositol monophosphatase 14004
Solute carrier organic anion transporter family member 1B30304
Solute carrier organic anion transporter family member 1B10305
Beta-lactamase 0105
Beta-lactamase 0104
Metallo-beta-lactamase VIM-19 0003
Beta-lactamase 0105
Albumin0033
Beta-lactamase 0002
Beta-lactamase 0105
Metallo-beta-lactamase VIM-20004
Solute carrier family 22 member 60303
Solute carrier family 22 member 70202
BlaVIM-1 0003
Beta-lactamase 0002
Solute carrier family 22 member 80507
Beta-lactamase 0103
Solute carrier family 22 member 110304
Solute carrier family 22 member 80506
Solute carrier family 22 member 70203
endonuclease IV2002
WRN2002
DNA (cytosine-5)-methyltransferase 1 isoform b0101
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Gamma-aminobutyric acid receptor subunit pi4308
Solute carrier family 22 member 80203
Beta-lactamase0103
Beta-lactamase0205
Beta-lactamase OXA-10103
Gamma-aminobutyric acid receptor subunit beta-14308
Gamma-aminobutyric acid receptor subunit delta4308
Gamma-aminobutyric acid receptor subunit gamma-24308
Gamma-aminobutyric acid receptor subunit alpha-54308
Gamma-aminobutyric acid receptor subunit alpha-34308
Gamma-aminobutyric acid receptor subunit gamma-14308
Gamma-aminobutyric acid receptor subunit alpha-24308
Gamma-aminobutyric acid receptor subunit alpha-44308
Gamma-aminobutyric acid receptor subunit gamma-34308
Gamma-aminobutyric acid receptor subunit alpha-64308
Beta-lactamase TEM0305
Gamma-aminobutyric acid receptor subunit alpha-14308
Gamma-aminobutyric acid receptor subunit beta-34308
Gamma-aminobutyric acid receptor subunit beta-24308
Beta-lactamase 0003
GABA theta subunit4308
Gamma-aminobutyric acid receptor subunit epsilon4308
phosphoglycerate kinase2002
Chain A, Ferritin light chain3003
caspase 7, apoptosis-related cysteine protease3003
estrogen receptor 2 (ER beta)9009
progesterone receptor110011
67.9K protein4004
caspase-33003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
thyrotropin-releasing hormone receptor2002
v-jun sarcoma virus 17 oncogene homolog (avian)100010
mitogen-activated protein kinase 15005
nuclear receptor ROR-gamma isoform 15005
Voltage-dependent calcium channel gamma-2 subunit5005
Glutamate receptor 25005
Caspase-20011
ATPase family AAA domain-containing protein 55005
EWS/FLI fusion protein8008
G6006
cytochrome P450 2D65005
aryl hydrocarbon receptor8008
streptokinase A precursor0055
Dihydroxyacetone phosphate acyltransferase0002
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 6006
30S ribosomal protein S60314
30S ribosomal protein S70314
50S ribosomal protein L150314
50S ribosomal protein L100314
50S ribosomal protein L110314
50S ribosomal protein L7/L120314
50S ribosomal protein L190314
50S ribosomal protein L10314
50S ribosomal protein L200314
50S ribosomal protein L270314
50S ribosomal protein L280314
50S ribosomal protein L290314
50S ribosomal protein L310314
50S ribosomal protein L31 type B0314
50S ribosomal protein L320314
50S ribosomal protein L330314
50S ribosomal protein L340314
50S ribosomal protein L350314
50S ribosomal protein L360314
30S ribosomal protein S100314
30S ribosomal protein S110314
30S ribosomal protein S120314
30S ribosomal protein S130314
30S ribosomal protein S160314
30S ribosomal protein S180314
30S ribosomal protein S190314
30S ribosomal protein S200314
30S ribosomal protein S20314
30S ribosomal protein S30314
30S ribosomal protein S40314
30S ribosomal protein S50314
30S ribosomal protein S80314
30S ribosomal protein S90314
50S ribosomal protein L130314
50S ribosomal protein L140314
50S ribosomal protein L160314
50S ribosomal protein L230314
30S ribosomal protein S150314
50S ribosomal protein L170314
50S ribosomal protein L210314
50S ribosomal protein L300314
50S ribosomal protein L60314
30S ribosomal protein S140314
30S ribosomal protein S170314
30S ribosomal protein S10314
50S ribosomal protein L180314
50S ribosomal protein L20314
50S ribosomal protein L30314
50S ribosomal protein L240314
50S ribosomal protein L40314
50S ribosomal protein L220314
50S ribosomal protein L50314
30S ribosomal protein S210314
50S ribosomal protein L250314
50S ribosomal protein L36 20314
Inositol hexakisphosphate kinase 16006
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial6006
Carbonic anhydrase 40102
Carbonic anhydrase0102
Carbonic anhydrase 150102
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120202
Protein-arginine deiminase type-40505
thyroid stimulating hormone receptor3003
alpha-galactosidase1001
cytochrome P450 2C19 precursor3003
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 85005
Solute carrier family 22 member 10101
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0202
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10517
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10303
Histamine H2 receptor0606
Histamine H1 receptor0123
Histamine H2 receptor2215
Potassium-transporting ATPase subunit beta0101
Aldehyde oxidase0202
Solute carrier family 22 member 10202
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10404
Histamine H4 receptor0213
Solute carrier family 22 member 20202
Solute carrier family 22 member 40101
cytochrome P450 2C9 precursor2002
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0205
DNA gyrase subunit B0205
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA topoisomerase 2-alpha0104
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0203
DNA gyrase subunit A0203
Enoyl-[acyl-carrier-protein] reductase [NADH]0002
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
5-hydroxytryptamine receptor 3E0101
Luciferase3003
ATAD5 protein, partial3003
Fumarate hydratase2002
polyprotein2002
Beta-1 adrenergic receptor 0101
glucocerebrosidase2002
bromodomain adjacent to zinc finger domain 2B5005
Adenylate cyclase type 1 0101
cytochrome P450 2D6 isoform 11001
peripheral myelin protein 22 isoform 13003
potassium voltage-gated channel subfamily H member 2 isoform d2002
atrial natriuretic peptide receptor 2 precursor1001
short transient receptor potential channel 6 isoform 10011
transient receptor potential cation channel subfamily V member 11001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 40404
5-hydroxytryptamine receptor 3B0101
Albumin0011
Aldo-keto reductase family 1 member B10606
Muscarinic acetylcholine receptor M20718
Muscarinic acetylcholine receptor M40617
Muscarinic acetylcholine receptor M10314
Muscarinic acetylcholine receptor M30314
Muscarinic acetylcholine receptor M40314
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M50314
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0606
Calmodulin-10101
Beta-2 adrenergic receptor0202
Muscarinic acetylcholine receptor M20314
Muscarinic acetylcholine receptor M10617
Angiotensin-converting enzyme0202
D(2) dopamine receptor0205
Alpha-1B adrenergic receptor0516
Beta-1 adrenergic receptor0101
Alpha-2C adrenergic receptor0606
D0202
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0213
D(2) dopamine receptor0202
Muscarinic acetylcholine receptor M30617
Endothelin receptor type B0101
D(1A) dopamine receptor0203
D(4) dopamine receptor0204
D(1B) dopamine receptor0102
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0213
UDP-glucuronosyltransferase 1A40002
Alpha-2A adrenergic receptor0213
Alpha-1D adrenergic receptor0314
Sodium-dependent noradrenaline transporter 0606
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 3A0101
Endothelin receptor type B0101
Adenosine receptor A10101
Alpha-1D adrenergic receptor0404
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2A0608
5-hydroxytryptamine receptor 2C0415
D(4) dopamine receptor0202
Histamine H1 receptor0202
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0226
Alpha-1B adrenergic receptor0101
D(3) dopamine receptor0608
Adenylate cyclase type 80101
5-hydroxytryptamine receptor 2B0415
Alpha-1A adrenergic receptor0516
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60405
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0101
D(2) dopamine receptor0202
Calmodulin 0011
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 0303
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Transporter0101
Cholecystokinin receptor type A0101
5-hydroxytryptamine receptor 1A0101
Nuclear receptor subfamily 3 group C member 3 0202
5-hydroxytryptamine receptor 3D0101
Adenylyl cyclase 7 0101
5-hydroxytryptamine receptor 3C0101
D0202
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10303
Transporter0101
Histamine H3 receptor0101
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor010318
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-1010010
Corticosteroid-binding globulin0202
Glycine receptor subunit beta010010
Glycine receptor subunit alpha-2010010
Glycine receptor subunit alpha-3010010
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 432002
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
Chain A, DigA160011
Chain A, DigA160011
PAX80001
glp-1 receptor, partial3003
Smad33003
thyroid stimulating hormone receptor5005
NPC intracellular cholesterol transporter 1 precursor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
ras-related protein Rab-9A2002
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-20101
Solute carrier organic anion transporter family member 4C10202
Rap guanine nucleotide exchange factor 41001
ClpP1001
Glycoprotein hormones alpha chain1001
chaperonin-containing TCP-1 beta subunit homolog1001
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Epidermal growth factor receptor0101
Estrogen receptor0617
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Fyn0101
Adenosine receptor A30202
Beta-3 adrenergic receptor0202
Substance-K receptor0202
Prostaglandin G/H synthase 10101
C-8 sterol isomerase0101
Alpha-synuclein1102
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
Rap guanine nucleotide exchange factor 35005
60 kDa chaperonin0202
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 1B10101
Lanosterol 14-alpha demethylase0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 1 0416
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0416
Glutamate receptor ionotropic, NMDA 2B0416
Glutamate receptor ionotropic, NMDA 2C0417
Large neutral amino acids transporter small subunit 10404
Glutamate receptor ionotropic, NMDA 2D0416
Proton-coupled amino acid transporter 10303
Glutamate receptor ionotropic, NMDA 3B0416
Serine racemase0101
Olfactory receptor 51E20022
Glutamate receptor ionotropic, NMDA 3A0416
Sodium- and chloride-dependent glycine transporter 20101
Glutaminyl-peptide cyclotransferase0101
Multidrug transporter MdfA0202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
PPM1D protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
nonstructural protein 11001
nuclear receptor subfamily 1, group I, member 22002
muscleblind-like protein 1 isoform 12002
Nuclear receptor subfamily 1 group I member 20022
Androgen receptor0506
Nuclear receptor subfamily 1 group I member 20011
STE240001
CAAX prenyl protease0001
histone acetyltransferase KAT2A isoform 14004
Trypsin0001
Valosin-containing protein0101
lysosomal alpha-glucosidase preproprotein1001
transcriptional regulator ERG isoform 31001
microphthalmia-associated transcription factor isoform 90101
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Serum paraoxonase/arylesterase 10101
Beta-lactamase 0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0102
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10012
Cytochrome P450 2B60303
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
luciferase0001
Fatty acid-binding protein, liver0101
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0416
Androgen receptor0415
Glutamine synthetase0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0314
N0101
NPYLR7B0022
cystic fibrosis transmembrane conductance regulator0101
serine/threonine-protein kinase mTOR isoform 11001
tumor susceptibility gene 101 protein1001
Glutathione reductase, mitochondrial0101
Riboflavin-binding protein0224
Major prion protein0011
Major prion protein0101
Histidine-rich protein PFHRP-II0101
DNA-directed RNA polymerase subunit alpha0101
DNA-directed RNA polymerase subunit omega0101
DNA-directed RNA polymerase subunit beta'0101
DNA-directed RNA polymerase subunit beta0101
Replicase polyprotein 1ab0101
Phospholipase A2, membrane associated0101
Phospholipase A2, membrane associated0101
Acidic phospholipase A2 20101
Acetylcholinesterase0101
Trypanothione reductase0202
D(1A) dopamine receptor1001
Aldehyde oxidase 10101
Cholinesterase0101
Cyclic GMP-AMP synthase0101
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
nuclear factor NF-kappa-B p105 subunit isoform 11001
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Vpr1001
GALC protein1001
Sodium- and chloride-dependent taurine transporter0101
Beta-lactamase 0101
B2 bradykinin receptor0101
Beta-lactamase0101
Beta-lactamase0101
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
Metallo-beta-lactamase L1 type 30101
Beta-lactamase 0101
Beta-lactamase 0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10202
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
Taste receptor type 2 member 380001
Solute carrier organic anion transporter family member 2A10001
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Carbonic anhydrase 120001
Plasma kallikrein0001
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Carbonic anhydrase 60001
Substance-P receptor0101
Carbonic anhydrase 5A, mitochondrial0001
Carbonic anhydrase 70001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 130001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
Urease subunit alpha0101
Urease subunit beta0101
Sterol 14-alpha-demethylase0011
14-alpha sterol demethylase 0011
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Lanosterol 14-alpha demethylase0011
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Sterol 14-alpha demethylase0011
14-alpha sterol demethylase 0011
14-alpha sterol demethylase 0011
Cholesterol 24-hydroxylase0213
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]