| Member | Definition | Role |
|---|
| 1-ethyl-2-benzo[cd]indolone | | 1-ethyl-2-benzo[cd]indolone |
| 2-(1,3-benzodioxol-5-ylmethyl)-3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-3H-isoindol-1-one | | 2-(1,3-benzodioxol-5-ylmethyl)-3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-3H-isoindol-1-one |
| 2-(2-ethoxyphenyl)-5,6-dimethyl-1,3-dihydroisoindole | | 2-(2-ethoxyphenyl)-5,6-dimethyl-1,3-dihydroisoindole |
| 2-(2-furanylmethyl)-3-[[2-(3-pyridinyl)-3H-benzimidazol-5-yl]amino]-3H-isoindol-1-one | | 2-(2-furanylmethyl)-3-[[2-(3-pyridinyl)-3H-benzimidazol-5-yl]amino]-3H-isoindol-1-one |
| 2-(2-methoxyethyl)-7-[oxo-(4-propyl-1-piperazinyl)methyl]-3H-isoindol-1-one | | 2-(2-methoxyethyl)-7-[oxo-(4-propyl-1-piperazinyl)methyl]-3H-isoindol-1-one |
| 2-(2-oxo-1-benzo[cd]indolyl)-N-(2-oxolanylmethyl)acetamide | | 2-(2-oxo-1-benzo[cd]indolyl)-N-(2-oxolanylmethyl)acetamide |
| 2-(4-methylphenyl)-1,9b-dihydropyrazolo[1,5-b]isoindol-5-one | | 2-(4-methylphenyl)-1,9b-dihydropyrazolo[1,5-b]isoindol-5-one |
| 2-(5-chloro-2-pyridinyl)-3-(4-ethoxyanilino)-3H-isoindol-1-one | | 2-(5-chloro-2-pyridinyl)-3-(4-ethoxyanilino)-3H-isoindol-1-one |
| 2-(5H-[1,2,4]triazolo[5,1-a]isoindol-2-yl)ethanethioamide | | 2-(5H-[1,2,4]triazolo[5,1-a]isoindol-2-yl)ethanethioamide |
| 2-amino-7-cyclohexyl-6,8-dioxo-4,5,5a,8a-tetrahydrothieno[2,3-e]isoindole-3-carboxylic acid ethyl ester | | 2-amino-7-cyclohexyl-6,8-dioxo-4,5,5a,8a-tetrahydrothieno[2,3-e]isoindole-3-carboxylic acid ethyl ester |
| 3-(2-ethoxyanilino)-2-(2-furanylmethyl)-3H-isoindol-1-one | | 3-(2-ethoxyanilino)-2-(2-furanylmethyl)-3H-isoindol-1-one |
| 3-(4-ethylphenyl)imino-1-isoindolamine | | 3-(4-ethylphenyl)imino-1-isoindolamine |
| 3-[(5-chloro-2-pyridinyl)amino]-2-(2-pyridinyl)-3H-isoindol-1-one | | 3-[(5-chloro-2-pyridinyl)amino]-2-(2-pyridinyl)-3H-isoindol-1-one |
| 3-[[2-(2-furanylmethyl)-3-oxo-1H-isoindol-1-yl]amino]benzoic acid ethyl ester | | 3-[[2-(2-furanylmethyl)-3-oxo-1H-isoindol-1-yl]amino]benzoic acid ethyl ester |
| 4-(dimethylsulfamoyl)-N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamide | | 4-(dimethylsulfamoyl)-N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamide |
| 4-[[[(1-ethyl-2-oxo-6-benzo[cd]indolyl)amino]-oxomethyl]amino]benzoic acid ethyl ester | | 4-[[[(1-ethyl-2-oxo-6-benzo[cd]indolyl)amino]-oxomethyl]amino]benzoic acid ethyl ester |
| 4-[[[2-(4-methoxyphenyl)-3-oxo-1H-isoindol-4-yl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester | | 4-[[[2-(4-methoxyphenyl)-3-oxo-1H-isoindol-4-yl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester |
| 4-[[3-oxo-2-(3-pyridinyl)-1H-isoindol-1-yl]amino]benzoic acid ethyl ester | | 4-[[3-oxo-2-(3-pyridinyl)-1H-isoindol-1-yl]amino]benzoic acid ethyl ester |
| 4-[3-oxo-1-(3,4,5-trimethoxyanilino)-1H-isoindol-2-yl]-1-piperidinecarboxylic acid ethyl ester | | 4-[3-oxo-1-(3,4,5-trimethoxyanilino)-1H-isoindol-2-yl]-1-piperidinecarboxylic acid ethyl ester |
| 4-[4-[[[1-(2-methylpropyl)-3-pyrrolidinyl]methylamino]-oxomethyl]-3-oxo-1H-isoindol-2-yl]-1-piperidinecarboxylic acid ethyl ester | | 4-[4-[[[1-(2-methylpropyl)-3-pyrrolidinyl]methylamino]-oxomethyl]-3-oxo-1H-isoindol-2-yl]-1-piperidinecarboxylic acid ethyl ester |
| 6,7-dimethoxy-2-(2-thiazolyl)-3H-isoindol-1-one | | 6,7-dimethoxy-2-(2-thiazolyl)-3H-isoindol-1-one |
| at 13387 | A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor. | onalespib |
| captafol | A dicarboximide that captan in which the trichloromethyl group is replaced by a 1,1,2,2-tetrachloroethyl group. A broad-spectrum fungicide used to control diseases in fruit and potatoes, it is no longer approved for use in the European Community. | captafol |
| captan | A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. | captan |
| chlorisondamine | | chlorisondamine |
| chlorthalidone | | chlorthalidone |
| cinidon-ethyl | A carboxylic ester and organochlorine compound that is the ethyl ester of cinidon. | cinidon ethyl |
| dialifor | | Dialifor |
| garenoxacin | A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by a cyclopropyl group at position 1, an oxo group at position 4, a (1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl group at position 7, and a difluoromethoxy group at position 8. | garenoxacin |
| indobufen | | indobufen |
| indoprofen | A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein. | indoprofen |
| lenalidomide | A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. | lenalidomide |
| LSM-17324 | | LSM-17324 |
| LSM-17343 | | LSM-17343 |
| LSM-19437 | | LSM-19437 |
| LSM-20631 | | LSM-20631 |
| LSM-25805 | | LSM-25805 |
| LSM-28383 | | LSM-28383 |
| LSM-32057 | | LSM-32057 |
| LSM-4844 | | LSM-4844 |
| N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamide | | N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamide |
| N-(2-furanylmethyl)-3-(2-furanylmethylimino)-1-isoindolamine | | N-(2-furanylmethyl)-3-(2-furanylmethylimino)-1-isoindolamine |
| N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-4-carboxamide | | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-4-carboxamide |
| N-[[1,3-dioxo-2-(phenylmethyl)-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]-4-methoxybenzamide | | N-[[1,3-dioxo-2-(phenylmethyl)-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]-4-methoxybenzamide |
| N-Benzylphthalimide | | N-Benzylphthalimide |
| N-cycloheptyl-1-hydroxy-3-oxo-2-propyl-1H-isoindole-5-carboxamide | | N-cycloheptyl-1-hydroxy-3-oxo-2-propyl-1H-isoindole-5-carboxamide |
| phthalimidine | A member of the class of isoindoles that is 2,3-dihydro-1H-isoindole in which the hydrogens at positon 1 are replaced by an oxo group. | isoindolin-1-one |
| pomalidomide | An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. | pomalidomide |
| rs 45041-190 | | 4-chloro-2-(4,5-dihydro-1H-imidazol-2-yl)-1,3-dihydroisoindole |