Page last updated: 2024-08-05 12:17:00

thiazolidines

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ChEBI ID: 35622

Members (8)

MemberDefinitionRole
3-(5-cycloheptylidene-4-oxo-2-sulfanylidene-3-thiazolidinyl)propanoic acid3-(5-cycloheptylidene-4-oxo-2-sulfanylidene-3-thiazolidinyl)propanoic acid
5-cyclopentylidene-2-sulfanylidene-4-thiazolidinone5-cyclopentylidene-2-sulfanylidene-4-thiazolidinone
epalrestatA monocarboxylic acid that is 1,3-thiazolidine which is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used for the treatment of some diabetic complications, including neuropathy.epalrestat
lugduninA thiazolidine-containing homodetic cyclic peptide that is isolated from human nasal bacteria. Exhibits bactericidal activity against many major pathogens including methicillin-resistant Staphylococcus aureus (MRSA).lugdunin
n-nitrosothiazolidineN-nitroso-1,3-thiazolidine
pyochelinA member of the class of thiazolidines that is (4R)-3-methyl-1,3-thiazolidine-4-carboxylic acid which is substituted at position 2 by a (4R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl group. A siderophore that is produced by Pseudomonas aeruginosa (via condensation of salicylic acid and two molecules of cysteine) as a mixture of two easily interconvertible diastereoisomers, pyochelin I (major) and pyochelin II (minor). The enantiomeric compounds, enant-pyochelin, are produced by Pseudomonas fluorescens.pyochelin
thiaclopridA nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen.thiacloprid
yersiniabactinA member of the class of thiazolidines that is (4S)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid which is substituted at position 2 by a (1S)-1-hydroxy-1-{(4R)-2-[(4R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazolidin-4-yl}-2-methylpropan-2-yl group. A siderophore found in the gram-negative bacterium species, Yersinia enterocolitica and Yersinia pestis.yersiniabactin

Research

Studies (807)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199036 (4.46)18.7374
1990's92 (11.40)18.2507
2000's176 (21.81)29.6817
2010's337 (41.76)24.3611
2020's166 (20.57)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials23 (2.73%)5.53%
Reviews37 (4.40%)6.00%
Case Studies5 (0.59%)4.05%
Observational0 (0.00%)0.25%
Other776 (92.27%)84.16%