Page last updated: 2024-08-05 14:55:45

avicide

A substance used to destroy bird pests (class Aves).

ChEBI ID: 33289

Members (13)

MemberDefinitionClass
3-chloro-4-methylanilineA monochloroaniline that is p-toluidine in which one of the hydrogens that is meta to the amino group is replaced by a chlorine.3-chloro-p-toluidine
4-aminopyridineAn aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.4-aminopyridine
bay 93820isocarbophos
carbofurancarbofuran
coumaphoscoumaphos
dicrotophosdicrotophos
fensulfothionfensulfothion
fenthionAn organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities.fenthion
methamidophosAn organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate.methamidophos
methiocarbA carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid.methiocarb
monocrotophosAn alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate.monocrotophos
parathionparathion
strychnineA monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.strychnine

Research

Studies (12,376)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19905,200 (42.02)18.7374
1990's2,477 (20.01)18.2507
2000's2,464 (19.91)29.6817
2010's1,857 (15.00)24.3611
2020's378 (3.05)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials160 (1.20%)5.53%
Reviews334 (2.50%)6.00%
Case Studies406 (3.04%)4.05%
Observational12 (0.09%)0.25%
Other12,450 (93.17%)84.16%

Protein Targets (125)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency31.622811
acetylcholinesteraseHomo sapiens (human)Potency30.8404446
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency32.505215
AR proteinHomo sapiens (human)Potency26.3717830
aryl hydrocarbon receptorHomo sapiens (human)Potency26.4240327
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency0.756911
Cellular tumor antigen p53Homo sapiens (human)Potency13.476013
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency25.118911
Chain A, CruzipainTrypanosoma cruziPotency3.355222
Chain A, Ferritin light chainEquus caballus (horse)Potency35.481311
Chain A, HADH2 proteinHomo sapiens (human)Potency33.191313
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency65.941113
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency666.272213
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency39.810711
Chain B, HADH2 proteinHomo sapiens (human)Potency33.191313
chromobox protein homolog 1Homo sapiens (human)Potency68.338224
cytochrome P450 2C9, partialHomo sapiens (human)Potency5.404012
cytochrome P450 2D6Homo sapiens (human)Potency27.194412
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency0.063111
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency8.4372210
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency18.213213
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency19.547611
DNA dC->dU-editing enzyme APOBEC-3F isoform aHomo sapiens (human)Potency2.818411
estrogen nuclear receptor alphaHomo sapiens (human)Potency31.60951225
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency44.362626
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency25.2670614
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency22.345412
farnesoid X nuclear receptorHomo sapiens (human)Potency72.201035
GVesicular stomatitis virusPotency5.404012
GABA theta subunitRattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency8.437215
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency8.437215
gemininHomo sapiens (human)Potency16.119312
GLI family zinc finger 3Homo sapiens (human)Potency17.090029
glp-1 receptor, partialHomo sapiens (human)Potency22.387211
glucocerebrosidaseHomo sapiens (human)Potency0.631011
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency22.458133
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency28.258313
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency0.410911
Guanine nucleotide-binding protein GHomo sapiens (human)Potency50.118711
heat shock protein beta-1Homo sapiens (human)Potency42.109612
histone deacetylase 9 isoform 3Homo sapiens (human)Potency12.869022
Histone H2A.xCricetulus griseus (Chinese hamster)Potency87.577825
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency5.404012
IDH1Homo sapiens (human)Potency29.092911
importin subunit beta-1 isoform 1Homo sapiens (human)Potency44.768022
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency5.404014
Interferon betaHomo sapiens (human)Potency5.404012
lamin isoform A-delta10Homo sapiens (human)Potency5.005813
lethal factor (plasmid)Bacillus anthracis str. A2012Potency5.227612
LuciferasePhotinus pyralis (common eastern firefly)Potency46.640327
Microtubule-associated protein tauHomo sapiens (human)Potency8.912511
mitogen-activated protein kinase 1Homo sapiens (human)Potency5.001022
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency48.3042411
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency20.596211
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency49.397911
Nuclear receptor ROR-gammaHomo sapiens (human)Potency1.188311
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency26.6617339
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency12.019023
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency108.415744
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency29.466035
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency27.247615
pregnane X nuclear receptorHomo sapiens (human)Potency42.1774322
pregnane X receptorRattus norvegicus (Norway rat)Potency47.607815
progesterone receptorHomo sapiens (human)Potency9.808219
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency28.183811
RAR-related orphan receptor gammaMus musculus (house mouse)Potency26.9784212
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency19.6741316
retinoid X nuclear receptor alphaHomo sapiens (human)Potency38.421448
SMAD family member 2Homo sapiens (human)Potency15.132425
SMAD family member 3Homo sapiens (human)Potency15.132425
snurportin-1Homo sapiens (human)Potency44.768022
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency21.679412
survival motor neuron protein isoform dHomo sapiens (human)Potency1.000012
TAR DNA-binding protein 43Homo sapiens (human)Potency19.952611
TDP1 proteinHomo sapiens (human)Potency13.723223
thioredoxin reductaseRattus norvegicus (Norway rat)Potency89.125122
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency55.331413
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency25.560126
thyroid stimulating hormone receptorHomo sapiens (human)Potency24.3456723
transcriptional regulator ERG isoform 3Homo sapiens (human)Potency2.818411
USP1 protein, partialHomo sapiens (human)Potency14.125411
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency51.867611
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency12.864136
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency28.258313

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AcetylcholinesteraseRattus norvegicus (Norway rat)IC50500.000012
Carbonic anhydrase 1Homo sapiens (human)Ki61.700011
Carbonic anhydrase 12Homo sapiens (human)Ki9.520011
Carbonic anhydrase 13Homo sapiens (human)Ki4.230011
Carbonic anhydrase 14Homo sapiens (human)Ki4.140011
Carbonic anhydrase 2Homo sapiens (human)Ki200.000011
Carbonic anhydrase 3Homo sapiens (human)Ki4.620011
Carbonic anhydrase 4Homo sapiens (human)Ki5.480011
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki5.090011
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Ki3.410011
Carbonic anhydrase 6Homo sapiens (human)Ki2.230011
Carbonic anhydrase 7Homo sapiens (human)Ki4.680011
Carbonic anhydrase 9Homo sapiens (human)Ki6.410011
Glycine receptor subunit alpha-1Homo sapiens (human)IC500.18431420
Glycine receptor subunit alpha-1Homo sapiens (human)Ki0.050333
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)Ki0.012011
Glycine receptor subunit betaHomo sapiens (human)IC500.287169
Potassium voltage-gated channel subfamily A member 1Homo sapiens (human)IC5089.000011
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC504,382.580022
Pteridine reductase 1Leishmania majorIC501,900.000011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Potassium channel subfamily K member 2Homo sapiens (human)EC502,750.000011
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)Kd195.000011
Taste receptor type 2 member 10Homo sapiens (human)EC5022.500022
Taste receptor type 2 member 46Homo sapiens (human)EC500.690011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Gamma-aminobutyric acid receptor subunit rho-1Homo sapiens (human)Kb69.000011
Gamma-aminobutyric acid receptor subunit rho-2Homo sapiens (human)Kb69.000011
Gamma-aminobutyric acid receptor subunit rho-3Homo sapiens (human)Kb69.000011
Taste receptor type 2 member 10Homo sapiens (human)Activity1.550022