Osteosclerosis

Synonym
Osteosclerosis

Excerpt	Reference
"The osteosclerosis is due to an effect of estrogens to reduce osteoclast numbers and a lesser inhibitory effect on the bone-forming activity of osteoblasts and osteocytes."	( Capen, CC; Weisbrode, SE, 1977)
"In conclusion, osteosclerosis is the commonest radiological finding in our dialysis patients while secondary hyperparathyroidism is the main histopathological diagnosis in bone biopsy, even in patients with normal skeletal survey."	( al-Swailem, AR; Aswad, S; Huraib, S; Souqqiyeh, MZ, 1993)
"Osteosclerosis is a rare complication of hepatitis C infection, the symptoms of which are controllable with diphosphonate therapy."	( Depczynski, B; Diamond, T, 1996)
"Myelofibrosis and osteosclerosis are prominent features arising in mice overexpressing thrombopoietin (TPO)."	( Chagraoui, H; Giraudier, S; Komura, E; Lassau, N; Smayra, T; Tulliez, M; Vainchenker, W; Wendling, F; Yun, T, 2003)
"Diffuse osteosclerosis is extremely rare and may lead to the diagnosis of multiple myeloma, classically known to present as lytic lesions in the skeleton, with or without diffuse osteoporosis."	( Cotten, A; Duquesnoy, B; Flipo, RM; Gaxatte, C; Guillerm, G; Leroy, X; Mulleman, D, 2004)
"Acquired osteosclerosis is a rare disorder of bone formation but an important consideration in adults with sclerotic bones or elevated bone density results."	( Doran, PM; Hallanger Johnson, JE; Kearns, AE; Khoo, TK; Wermers, RA, 2007)
"Additionally, if osteosclerosis is observed in a patient with LCH, the coexistence of ECD should be considered."	( Bao, Y; Hu, S; Jia, W; Li, Q; Shen, L; Tian, Q; Yin, J; Zhang, F; Zhang, H, 2013)
"Idiopathic osteosclerosis is a localized growth of compact bone with an unknown cause."	( Anvari, M; Azimi, F; Moshfeghi, M, 2014)

Excerpt	Reference
"Furthermore, osteosclerosis affects vertebral bodies, ribs, pelvis, mandible, clavicles, and scapulae."	( Econs, MJ; Hernandez, TP; Hernandez-Cassis, C; Howard, GA; Iglesias Gamarra, A; Iglesias, A; Iglesias, M; Levis, S; Roos, BA; Vogel, CK, 2003)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	287 (58.22)	23.3326
1990's	50 (10.14)	12.5806
2000's	68 (13.79)	18.1394
2010's	73 (14.81)	28.8240
2020's	15 (3.04)	9.53

Drug	Relationship Strength	Studies	Trials
quinacrine	low	1	0
carbamates	low	1	0
salicylic acid	low	2	0
creatine	low	1	0
formaldehyde	low	1	0
glutaric acid	low	1	0
glycine	low	1	0
glycerol	low	1	0
hydrogen carbonate	low	1	0
histamine	low	1	0
methanol	low	1	0
nitrous oxide	low	1	0
phosphoenolpyruvate	low	1	0
uric acid	low	3	0
urea	low	1	0
homovanillic acid	low	1	0
hydroxyindoleacetic acid	low	1	0
acetaminophen	low	1	0
acetazolamide	low	1	0
beta-aminoethyl isothiourea	low	1	0
alendronate	low	7	0
p-aminohippuric acid	low	1	0
azathioprine	low	1	0
busulfan	low	3	0
chlorambucil	low	1	0
cimetidine	low	1	0
pentetic acid	low	1	0
valproic acid	low	1	0
ethacrynic acid	low	1	0
etidronate	low	4	0
etodolac	low	1	0
fentanyl	low	1	0
flutamide	low	1	0
ibuprofen	low	1	0
lidocaine	low	1	0
indomethacin	low	2	0
isoflurane	low	1	0
2-propanol	low	1	0
ketotifen	low	1	0
khellin	low	1	0
metformin	low	1	0
methoxyflurane	low	1	0
metronidazole	low	1	0
niflumic acid	low	3	0
nilutamide	low	1	0
pamidronate	low	9	0
potassium chloride	low	1	0
probenecid	low	1	0
procaine	low	1	0
sodium fluoride	medium	10	1
risedronic acid	low	2	0
sulfamethazine	low	1	0
sulfanilamide	low	1	0
thalidomide	low	4	0
corticosterone	low	1	0
prednisolone	low	8	0
thymidine	low	1	0
hydroxyproline	low	7	0
prednisone	medium	11	1
estrone	low	3	0
penicillin g	low	2	0
triiodothyronine	low	1	0
isoflurophate	low	1	0
chloramphenicol	low	1	0
glutamine	low	1	0
sucrose	low	1	0
edetic acid	low	1	0
leucine	low	2	0
colchicine	low	2	0
ampicillin	low	2	0
mannitol	low	1	0
cytarabine	low	2	0
sulfobromophthalein sodium	low	1	0
valine	low	1	0
threonine	low	1	0
tryptophan	low	1	0
arginine	low	1	0
1,1-difluoroethane	low	1	0
taurocholic acid	low	1	0
methylprednisolone	low	1	0
n-butoxyethanol	low	1	0
tetrafluoroethylene	low	1	0
hexachlorobenzene	low	2	0
quinazolines	low	1	0
pyrazines	low	2	0
chlormadinone acetate	low	1	0
betamethasone	low	1	0
limestone	medium	12	1
reticulin	low	7	0
indican	low	1	0
c.i. 42510	low	1	0
durapatite	low	3	0
hydrofluoric acid	low	1	0
vancomycin	low	1	0
pimozide	low	1	0
carbonates	low	1	0
cladribine	low	1	0
vidarabine	low	1	0
technetium	low	8	0
thorium	low	1	0
titanium	medium	1	1
gadolinium	low	1	0
tricalcium phosphate	low	1	0
silver nitrate	low	1	0
fluorine	medium	4	1
trolamine salicylate	low	20	0
chloropyramine	low	1	0
clodronic acid	medium	2	1
cephalexin	low	1	0
cromolyn sodium	low	1	0
fluorides	medium	50	1
daunorubicin	low	2	0
cetylpyridinium chloride anhydrous	low	1	0
alkenes	low	1	0
calcium oxalate	low	1	0
amoxicillin	low	1	0
gallium citrate	low	1	0
zidovudine	low	1	0
ribavirin	low	1	0
propiconazole	low	3	0
fomesafen	low	1	0
pravastatin	low	2	0
ibandronic acid	low	2	0
fluorophosphate	low	3	0
fluorodeoxyglucose f18	low	3	0
zoledronic acid	low	8	0
pyridinoline	low	1	0
deoxypyridinoline	low	1	0
gefitinib	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
methotrexate	low	1	0
sulbactam	low	2	0
beta-lactams	low	1	0
proline	low	3	0
ertapenem	low	1	0
naproxen	low	2	0
lenalidomide	low	3	0
cortisone	low	2	0
bortezomib	low	2	0
cimadronate	low	1	0
bradykinin	low	1	0
elastin	low	2	0
tartaric acid	low	1	0
tretinoin	low	1	0
retinol	low	6	0
clindamycin	low	1	0
diethylstilbestrol	low	2	0
imidazolidines	low	1	0
cefamandole	low	1	0
melphalan	medium	13	1
dibekacin	low	1	0
sodium bicarbonate	low	1	0
pyrophosphate	low	2	0
propylthiouracil	low	1	0
mercaptopurine	low	1	0
indoxyl glucuronide	low	1	0
lincomycin	low	1	0
estrone sulfate	low	1	0
cystine	low	2	0
nitinol	medium	2	1
ovalbumin	low	1	0
osteoprotegerin	low	11	0
dinoprostone	low	2	0
calcitriol	low	8	0
vitamin k semiquinone radical	low	1	0
vitamin d 2	low	1	0
cholecalciferol	low	4	0
amphotericin b	low	1	0
estradiol-17 beta-glucuronide	low	1	0
isotretinoin	low	1	0
phenylephrine hydrochloride	low	3	0
sirolimus	low	1	0
morphine	low	1	0
aluminum	medium	8	1
strontium	low	2	0
arsenic	low	1	0
indium	low	1	0
gallium	low	1	0
indinavir sulfate	low	1	0
sulfur	low	3	0
cysteine	low	2	0
phosphorus	low	30	0
strontium radioisotopes	low	4	0
radium	low	1	0
oxalates	low	2	0
beta-escin	low	1	0
gadolinium dtpa	low	1	0
chlorhexidine	low	1	0
amoxicillin-potassium clavulanate combination	low	3	0
losartan potassium	low	2	0
dihydrotachysterol	low	3	0
acid phosphatase	low	10	0
1,25-dihydroxy-previtamin d(3)	low	1	0
jaw	low	6	0
desmosine	low	1	0
calcitonin	low	1	0
endothelin-1	low	2	0
sodium ethylxanthate	low	1	0
cabozantinib	low	1	0
incb-018424	low	1	0
bms-790052	low	1	0
plx4032	low	1	0
dabrafenib	low	1	0
sofosbuvir	low	1	0
chondroitin	low	1	0
ascorbic acid	low	1	0
tetracycline	low	3	0
transforming growth factor beta	low	10	0
agar	low	1	0
caseins	low	1	0
technetium tc 99m sulfur colloid	low	1	0
cyclosporine	low	1	0
technetium tc 99m medronate	low	13	0
thromboplastin	low	1	0
chondroitin sulfates	low	1	0
exudates	low	1	0
folic acid	low	1	0
allopurinol	low	1	0
phosphorus radioisotopes	low	2	0
leptin	low	1	0

Protein Targets (1,914)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	17	0	0	17
RAR-related orphan receptor gamma	46	0	0	46
GLI family zinc finger 3	53	0	0	53
AR protein	73	0	0	73
aldehyde dehydrogenase 1 family, member A1	37	0	0	37
retinoic acid nuclear receptor alpha variant 1	51	0	0	51
retinoid X nuclear receptor alpha	50	0	0	50
estrogen nuclear receptor alpha	80	0	0	80
peroxisome proliferator-activated receptor delta	36	0	0	36
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	36	0	0	36
activating transcription factor 6	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	19	0	0	19
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform a	23	0	0	23
heat shock protein beta-1	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 1	62	0	0	62
lamin isoform A-delta10	44	0	0	44
Voltage-dependent calcium channel gamma-2 subunit	34	0	0	34
Glutamate receptor 2	34	0	0	34
ATAD5 protein, partial	16	0	0	16
GLS protein	21	0	0	21
Microtubule-associated protein tau	22	0	0	22
Smad3	9	0	0	9
thyroid stimulating hormone receptor	35	0	0	35
nuclear receptor subfamily 1, group I, member 3	39	0	0	39
progesterone receptor	36	0	0	36
EWS/FLI fusion protein	36	0	0	36
estrogen-related nuclear receptor alpha	62	0	0	62
peroxisome proliferator activated receptor gamma	39	0	0	39
aryl hydrocarbon receptor	23	0	0	23
chromobox protein homolog 1	34	0	0	34
thyroid hormone receptor beta isoform 2	50	0	0	50
peripheral myelin protein 22	35	0	0	35
cytochrome P450 3A4 isoform 1	25	0	0	25
Gamma-aminobutyric acid receptor subunit pi	25	1	1	27
ATP-binding cassette sub-family C member 3	0	44	0	44
Multidrug resistance-associated protein 4	0	47	0	51
Solute carrier family 22 member 6	0	18	0	20
Carbonic anhydrase 12	0	9	1	14
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	10	0	11
Bile salt export pump	0	66	0	67
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	23	1	32
Carbonic anhydrase 2	0	24	4	36
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	8	1	12
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 3	0	6	1	11
Cytochrome P450 3A4	0	19	3	26
Cytochrome P450 2D6	0	10	1	12
Cytochrome P450 2C9	0	16	2	20
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	25	1	1	27
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	25	1	1	27
Gamma-aminobutyric acid receptor subunit gamma-2	25	1	1	27
UDP-glucuronosyltransferase 1-6	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	25	1	1	27
Gamma-aminobutyric acid receptor subunit alpha-3	25	1	1	27
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
Carbonic anhydrase 4	0	12	1	16
Prostaglandin G/H synthase 1	0	11	0	11
Carbonic anhydrase 6	0	8	1	12
Gamma-aminobutyric acid receptor subunit gamma-1	25	1	1	27
Gamma-aminobutyric acid receptor subunit alpha-2	25	1	1	27
Gamma-aminobutyric acid receptor subunit alpha-4	25	1	1	27
Gamma-aminobutyric acid receptor subunit gamma-3	25	1	1	27
Gamma-aminobutyric acid receptor subunit alpha-6	25	1	1	27
Carbonic anhydrase 5A, mitochondrial	0	10	1	16
Prostaglandin G/H synthase 2	0	12	3	16
Carbonic anhydrase 7	0	7	1	11
Nuclear receptor ROR-gamma	18	1	1	20
Cytochrome P450 2J2	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	25	2	1	28
Gamma-aminobutyric acid receptor subunit beta-3	25	1	1	27
Gamma-aminobutyric acid receptor subunit beta-2	25	1	1	27
Carbonic anhydrase 9	0	14	2	20
GABA theta subunit	25	1	1	27
Canalicular multispecific organic anion transporter 1	0	44	0	46
Carbonic anhydrase 15	0	8	0	11
Carbonic anhydrase 13	0	6	0	9
Gamma-aminobutyric acid receptor subunit epsilon	25	1	1	27
Carbonic anhydrase 14	0	7	1	12
Carbonic anhydrase 5B, mitochondrial	0	8	1	14
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	22	0	0	22
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	17	0	0	17
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	4	0	4
thioredoxin reductase	31	0	0	31
GALC protein	9	0	0	9
cytochrome P450 family 3 subfamily A polypeptide 4	31	0	0	31
glucocorticoid receptor [Homo sapiens]	52	0	0	52
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	3	0	3
arylsulfatase A	17	0	0	17
Carbonic anhydrase	0	3	0	3
euchromatic histone-lysine N-methyltransferase 2	54	0	0	54
Bloom syndrome protein isoform 1	18	0	0	18
geminin	57	0	0	57
survival motor neuron protein isoform d	25	0	0	25
muscleblind-like protein 1 isoform 1	14	0	0	14
Carbonic anhydrase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 2	0	3	1	4
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	4	0	5
5-hydroxytryptamine receptor 2C	0	3	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	2	0	2
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	14	0	14
Translocator protein	0	1	1	2
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	5	0	6
Serum paraoxonase/arylesterase 1	0	4	0	4
Dipeptidyl peptidase 4	0	2	0	3
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	5	0	6
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	5	0	6
Cytochrome P450 2C19	0	8	1	9
Delta-type opioid receptor	0	7	1	9
Mu-type opioid receptor	0	9	3	15
Carbonic anhydrase	0	9	0	11
Kappa-type opioid receptor	0	5	1	8
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	3	1	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	5
D(2) dopamine receptor	0	3	0	3
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	7	1	8
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	3	1	6
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	3	0	7
Carbonic anhydrase	0	2	0	6
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	4	1	5
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	5
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	7
Carbonic anhydrase 4	0	3	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	7	0	8
Farnesyl pyrophosphate synthase	0	12	0	12
Acetylcholinesterase	0	8	1	9
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	7	0	7
Farnesyl pyrophosphate synthase	0	3	0	3
interleukin 8	18	0	0	18
TDP1 protein	59	0	0	59
estrogen receptor 2 (ER beta)	28	0	0	28
IDH1	22	0	0	22
transcriptional regulator ERG isoform 3	6	0	0	6
ras-related protein Rab-9A	7	0	0	7
Polyphenol oxidase 2	0	3	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	54	0	0	54
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	3	1	4
Xanthine dehydrogenase/oxidase	0	2	0	2
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	2	2
TAR DNA-binding protein 43	13	0	0	13
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	26	0	0	26
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
apical membrane antigen 1, AMA1	8	0	0	8
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	24	0	0	24
urokinase-type plasminogen activator precursor	12	0	0	12
plasminogen precursor	12	0	0	12
urokinase plasminogen activator surface receptor precursor	12	0	0	12
DNA polymerase kappa isoform 1	15	0	0	15
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	1	0	3
Beta-lactamase	0	1	0	3
Solute carrier family 15 member 1	0	7	0	7
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	5	0	6
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, Cruzipain	10	0	0	10
phosphopantetheinyl transferase	23	0	0	23
farnesoid X nuclear receptor	34	0	0	34
vitamin D (1,25- dihydroxyvitamin D3) receptor	39	0	0	39
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	25	0	0	25
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
Aurora kinase B	0	1	6	7
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	9
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Beta-lactamase	0	0	0	2
acid sphingomyelinase	5	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	12	0	0	12
DNA polymerase beta	3	0	0	3
60 kDa heat shock protein, mitochondrial	0	7	0	7
Beta-lactamase OXA-7	0	0	0	1
Spike glycoprotein	23	0	1	24
10 kDa heat shock protein, mitochondrial	0	7	0	7
Angiopoietin-1 receptor	0	1	3	4
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Thiosulfate sulfurtransferase	0	7	0	7
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	7	0	7
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	7	0	7
Metallo-b-lactamase	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	3
Beta-lactamase class B VIM-2	0	0	0	4
Beta-lactamase VIM-1	0	1	0	3
ATP-dependent phosphofructokinase	22	0	0	22
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	11	0	0	11
alpha-galactosidase	8	0	0	8
cytochrome P450 2C19 precursor	13	0	0	13
flap endonuclease 1	11	0	0	11
muscarinic acetylcholine receptor M1	16	0	0	16
lethal factor (plasmid)	16	0	0	16
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	16	0	0	16
thioredoxin glutathione reductase	15	0	0	15
nuclear factor erythroid 2-related factor 2 isoform 2	19	0	0	19
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	1	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	8	1	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	2	0	0	2
cytochrome P450 2D6	19	0	0	19
glucocerebrosidase	7	0	0	7
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	9	7	16
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	8	2	0	10
Myeloperoxidase	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	8	1	0	9
Glutathione hydrolase 1 proenzyme	0	1	0	1
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	4	0	4
Solute carrier family 22 member 20	0	9	0	9
Solute carrier family 22 member 6	0	9	0	10
Sigma non-opioid intracellular receptor 1	0	4	1	5
Sigma non-opioid intracellular receptor 1	0	1	1	2
Chain A, Ferritin light chain	17	0	0	17
SMAD family member 2	12	0	0	12
Fumarate hydratase	15	0	0	15
SMAD family member 3	12	0	0	12
pregnane X nuclear receptor	47	0	0	47
G	28	0	0	28
polyprotein	15	0	0	15
P53	1	0	0	1
thyroid stimulating hormone receptor	15	0	0	15
peripheral myelin protein 22 isoform 1	15	0	0	15
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	12	0	0	12
M-phase phosphoprotein 8	16	0	0	16
Interferon beta	35	0	0	35
HLA class I histocompatibility antigen, B alpha chain	28	0	0	28
Inositol hexakisphosphate kinase 1	28	0	0	28
ATPase family AAA domain-containing protein 5	22	0	0	22
Ataxin-2	27	0	0	27
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	28	0	0	28
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
pregnane X receptor	16	0	0	16
Endolysin	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	15	2	22
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
tyrosine-protein kinase Yes	7	0	0	7
nuclear receptor ROR-gamma isoform 1	19	0	0	19
Estrogen receptor	0	7	2	10
Progesterone receptor	0	1	0	1
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	2	1	3
Androgen receptor	0	9	2	14
Androgen receptor	0	1	0	1
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Progesterone receptor	0	2	0	2
ALK tyrosine kinase receptor	0	1	3	4
PPM1D protein	8	0	0	8
5-hydroxytryptamine receptor 1A	0	5	0	5
Nonstructural protein 5A	0	1	1	2
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
caspase 7, apoptosis-related cysteine protease	11	0	0	11
caspase-3	11	0	0	11
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	3	0	3
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	1	1	2
Chymotrypsinogen A	0	2	0	2
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	6	7
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	2	0	2
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	4	0	4
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	3	0	3
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Angiotensin-converting enzyme	0	2	0	3
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	1	3	4
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
15-lipoxygenase, partial	12	0	0	12
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Matrix metalloproteinase-9	0	4	0	4
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Bone morphogenetic protein receptor type-1B	0	0	6	6
Membrane-associated progesterone receptor component 1	0	0	3	3
Cell division cycle 7-related protein kinase	0	0	5	5
Serine/threonine-protein kinase PLK4	0	0	6	6
ATP-dependent RNA helicase DDX3X	0	0	6	6
Pyridoxal kinase	0	0	6	6
Citron Rho-interacting kinase	0	0	6	6
Serine/threonine-protein kinase Chk1	0	0	6	6
Aurora kinase A	0	0	6	6
Cyclin-G-associated kinase	0	2	6	8
Ephrin type-B receptor 6	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 3	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 2	0	1	6	7
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	6	6
Dynamin-like 120 kDa protein, mitochondrial	0	0	6	6
Tyrosine-protein kinase JAK2	0	2	7	9
Eukaryotic translation initiation factor 5B	0	0	4	4
Rho-associated protein kinase 2	0	0	6	6
Serine/threonine-protein kinase ULK1	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	6	6
Ribosomal protein S6 kinase alpha-5	0	0	6	6
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	6	6
Ribosomal protein S6 kinase alpha-4	0	0	6	6
Serine/threonine-protein kinase 16	0	0	6	6
Serine/threonine-protein kinase 10	0	0	6	6
Serine/threonine-protein kinase D3	0	0	6	6
Structural maintenance of chromosomes protein 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 6	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	6	6
Serine/threonine-protein kinase LATS1	0	0	6	6
Serine/threonine-protein kinase PAK 4	0	0	6	6
Tyrosine-protein kinase ABL1	0	2	7	10
High affinity nerve growth factor receptor	0	1	6	7
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	5	5
ADP/ATP translocase 2	0	0	6	6
Protein kinase C beta type	0	1	6	7
Insulin receptor	0	1	6	7
Tyrosine-protein kinase Lck	0	0	6	6
Tyrosine-protein kinase Fyn	0	2	6	8
Cyclin-dependent kinase 1	0	0	6	6
Glycogen phosphorylase, liver form	0	0	6	6
Acyl-CoA desaturase 1	0	2	0	2
Tyrosine-protein kinase Fes/Fps	0	0	6	6
Adenine phosphoribosyltransferase	0	0	5	5
Tyrosine-protein kinase Yes	0	0	6	6
Tyrosine-protein kinase Lyn	0	0	6	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	6	9
Insulin-like growth factor 1 receptor	0	1	6	7
Signal recognition particle receptor subunit alpha	0	0	4	4
Cytochrome c1, heme protein, mitochondrial	0	0	6	6
Hepatocyte growth factor receptor	0	1	6	8
Tyrosine-protein kinase HCK	0	1	6	7
Platelet-derived growth factor receptor beta	0	0	6	6
Serine/threonine-protein kinase A-Raf	0	2	6	8
Mast/stem cell growth factor receptor Kit	0	1	2	3
Glycogen phosphorylase, brain form	0	0	6	6
Breakpoint cluster region protein	0	0	6	7
Serine/threonine-protein kinase pim-1	0	1	6	7
Fibroblast growth factor receptor 1	0	2	6	8
Cyclin-dependent kinase 4	0	0	6	6
ADP/ATP translocase 3	0	0	6	6
Inosine-5'-monophosphate dehydrogenase 2	0	0	6	6
Proto-oncogene tyrosine-protein kinase Src	0	3	6	9
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Serine/threonine-protein kinase B-raf	0	3	8	13
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	6	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	6	6
Platelet-derived growth factor receptor alpha	0	1	2	3
Tyrosine-protein kinase Fer	0	0	6	6
Protein kinase C alpha type	0	0	6	6
cAMP-dependent protein kinase catalytic subunit alpha	0	0	6	6
Vascular endothelial growth factor receptor 1	0	1	2	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	6	6
Casein kinase II subunit alpha'	0	0	6	6
Ras-related protein Rab-6A	0	0	5	5
Multifunctional protein ADE2	0	0	6	6
cAMP-dependent protein kinase catalytic subunit gamma	0	0	4	4
cAMP-dependent protein kinase catalytic subunit beta	0	0	6	6
Ferrochelatase, mitochondrial	0	0	7	7
Ribosomal protein S6 kinase beta-1	0	0	6	6
Tyrosine-protein kinase JAK1	0	2	7	9
Cyclin-dependent kinase 2	0	0	7	7
Beta-adrenergic receptor kinase 1	0	0	6	6
Probable ATP-dependent RNA helicase DDX6	0	0	6	6
Mitogen-activated protein kinase 3	0	0	6	6
MAP/microtubule affinity-regulating kinase 3	0	0	6	6
Deoxycytidine kinase	0	0	6	8
Mitogen-activated protein kinase 1	0	2	6	8
Ephrin type-A receptor 2	0	0	6	6
Ephrin type-B receptor 2	0	0	6	6
Non-receptor tyrosine-protein kinase TYK2	0	2	7	9
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	6	6
Wee1-like protein kinase	0	0	6	6
Heme oxygenase 2	0	0	6	6
Tyrosine-protein kinase receptor UFO	0	1	2	3
S-adenosylmethionine synthase isoform type-2	0	0	6	6
DnaJ homolog subfamily A member 1	0	0	6	6
RAC-alpha serine/threonine-protein kinase	0	0	6	6
RAC-beta serine/threonine-protein kinase	0	0	6	6
Kinesin-1 heavy chain	0	2	0	2
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	6	6
Myosin-10	0	0	5	5
Vascular endothelial growth factor receptor 3	0	1	2	3
Vascular endothelial growth factor receptor 2	0	4	2	7
Dual specificity mitogen-activated protein kinase kinase 2	0	2	6	8
Receptor-type tyrosine-protein kinase FLT3	0	1	6	7
Bone morphogenetic protein receptor type-1A	0	0	6	6
Activin receptor type-1B	0	0	6	6
TGF-beta receptor type-1	0	1	6	7
TGF-beta receptor type-2	0	0	6	6
Electron transfer flavoprotein subunit beta	0	0	6	6
Tyrosine-protein kinase CSK	0	0	6	6
Glycine--tRNA ligase	0	0	6	6
Protein kinase C iota type	0	0	6	6
Exosome RNA helicase MTR4	0	0	6	6
Tyrosine-protein kinase Tec	0	0	6	6
Tyrosine-protein kinase ABL2	0	0	6	6
Tyrosine-protein kinase FRK	0	0	6	6
Tyrosine-protein kinase SYK	0	0	6	6
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 3	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	6	6
Casein kinase I isoform alpha	0	1	6	7
Casein kinase I isoform delta	0	0	6	6
MAP kinase-activated protein kinase 2	0	0	6	6
Elongation factor Tu, mitochondrial	0	0	6	6
Cysteine--tRNA ligase, cytoplasmic	0	0	6	6
Casein kinase I isoform epsilon	0	0	6	6
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	6	6
Dual specificity protein kinase CLK1	0	0	6	6
Dual specificity protein kinase CLK2	0	0	6	6
Dual specificity protein kinase CLK3	0	0	5	5
Glycogen synthase kinase-3 alpha	0	0	6	6
Glycogen synthase kinase-3 beta	0	0	6	6
Cyclin-dependent kinase 7	0	0	6	6
Cyclin-dependent kinase 9	0	0	6	6
Ras-related protein Rab-27A	0	0	6	6
Interleukin-1 receptor-associated kinase 1	0	0	6	6
Ribosomal protein S6 kinase alpha-3	0	0	6	6
Serine/threonine-protein kinase Nek2	0	0	6	6
Serine/threonine-protein kinase Nek3	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 6	0	1	6	7
Serine/threonine-protein kinase PLK1	0	0	6	6
LIM domain kinase 1	0	0	6	6
LIM domain kinase 2	0	0	6	6
Mitogen-activated protein kinase 10	0	0	6	6
Tyrosine--tRNA ligase, cytoplasmic	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
Ephrin type-B receptor 3	0	0	6	6
Ephrin type-A receptor 5	0	0	6	6
Ephrin type-B receptor 4	0	1	6	7
Ephrin type-A receptor 4	0	0	6	6
Adenylate kinase 2, mitochondrial	0	0	6	6
Adenosine kinase	0	0	6	6
Ras-related protein Rab-10	0	0	6	6
Actin-related protein 3	0	0	6	6
Actin-related protein 2	0	0	6	6
GTP-binding nuclear protein Ran	0	0	6	6
Casein kinase I isoform gamma-2	0	0	6	6
Cyclin-dependent kinase 3	0	0	5	5
Cyclin-dependent kinase 6	0	0	6	6
Cyclin-dependent-like kinase 5	0	0	6	6
Cyclin-dependent kinase 16	0	0	6	6
Cyclin-dependent kinase 17	0	0	6	6
ATP-dependent 6-phosphofructokinase, platelet type	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 1	0	2	6	8
DNA topoisomerase 2-beta	0	0	6	6
Protein kinase C theta type	0	0	6	6
Activin receptor type-1	0	0	6	6
Macrophage-stimulating protein receptor	0	1	6	7
Focal adhesion kinase 1	0	0	6	6
Protein kinase C zeta type	0	0	4	4
Protein kinase C delta type	0	0	6	6
Tyrosine-protein kinase BTK	0	0	6	6
Activated CDC42 kinase 1	0	0	6	6
Epithelial discoidin domain-containing receptor 1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	6	6
Serine/threonine-protein kinase 4	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase 7	0	0	6	6
Serine/threonine-protein kinase PAK 2	0	0	6	6
Serine/threonine-protein kinase 3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 1	0	0	6	6
Integrin-linked protein kinase	0	0	6	6
Rho-associated protein kinase 1	0	0	6	6
Non-receptor tyrosine-protein kinase TNK1	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	6	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	6	6
Activin receptor type-2B	0	0	6	6
Bone morphogenetic protein receptor type-2	0	0	6	6
Protein-tyrosine kinase 6	0	0	6	6
cGMP-dependent protein kinase 1	0	0	6	6
Cyclin-dependent kinase 13	0	0	6	6
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	6	6
Protein-tyrosine kinase 2-beta	0	0	6	6
Maternal embryonic leucine zipper kinase	0	0	6	6
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	6	6
Peroxisomal acyl-coenzyme A oxidase 1	0	0	6	6
Ephrin type-A receptor 7	0	0	4	4
Delta(24)-sterol reductase	0	0	6	6
Ribosomal protein S6 kinase alpha-1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	0	6	6
Mitogen-activated protein kinase 11	0	0	6	6
Serine/threonine-protein kinase STK11	0	0	6	6
Coiled-coil domain-containing protein 6	0	2	0	2
Serine/threonine-protein kinase N1	0	0	6	6
Serine/threonine-protein kinase N2	0	0	6	6
Mitogen-activated protein kinase 14	0	2	6	8
Calcium/calmodulin-dependent protein kinase type IV	0	0	6	6
Mitogen-activated protein kinase kinase kinase 11	0	0	6	6
Discoidin domain-containing receptor 2	0	0	6	6
AP2-associated protein kinase 1	0	1	6	7
Myosin light chain kinase 3	0	0	6	6
Putative heat shock protein HSP 90-beta 2	0	0	6	6
Rab-like protein 3	0	0	3	3
Serine/threonine-protein kinase MRCK alpha	0	0	6	6
Serine/threonine-protein kinase MRCK gamma	0	0	6	6
Acyl-CoA dehydrogenase family member 10	0	0	6	6
Serine/threonine-protein kinase ULK3	0	0	6	6
Uncharacterized protein FLJ45252	0	0	6	6
Acyl-CoA dehydrogenase family member 11	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	6	6
Serine/threonine-protein kinase MARK2	0	0	6	6
ATP-dependent RNA helicase DHX30	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	6	6
Myosin-14	0	0	6	6
AarF domain-containing protein kinase 1	0	0	6	6
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	6	6
MAP kinase-activated protein kinase 5	0	0	6	6
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	5	5
Atypical kinase COQ8A, mitochondrial	0	0	6	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	6	6
Mitogen-activated protein kinase 15	0	0	6	6
Serine/threonine-protein kinase Nek9	0	0	6	6
Serine/threonine-protein kinase Nek7	0	0	4	4
ATP-dependent RNA helicase DDX1	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	6	6
MAP/microtubule affinity-regulating kinase 4	0	0	6	6
Serine/threonine-protein kinase Nek1	0	0	6	6
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	6	6
EKC/KEOPS complex subunit TP53RK	0	0	6	6
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	6	6
Mitogen-activated protein kinase kinase kinase 5	0	0	6	6
Mitogen-activated protein kinase kinase kinase 3	0	0	6	6
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	6	6
Nucleolar GTP-binding protein 1	0	0	6	6
Serine/threonine-protein kinase D2	0	0	6	6
NUAK family SNF1-like kinase 2	0	0	5	5
RNA cytidine acetyltransferase	0	0	6	6
Serine/threonine-protein kinase SIK2	0	0	6	6
STE20-like serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO3	0	0	6	6
dCTP pyrophosphatase 1	0	0	6	6
Dual specificity protein kinase CLK4	0	0	6	6
Casein kinase I isoform gamma-1	0	0	6	6
Serine/threonine-protein kinase PAK 6	0	0	4	4
Phenylalanine--tRNA ligase beta subunit	0	0	6	6
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
BMP-2-inducible protein kinase	0	0	6	6
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	6	6
SAFB-like transcription modulator	0	1	0	1
Interleukin-1 receptor-associated kinase 4	0	0	6	6
Mitogen-activated protein kinase kinase kinase 20	0	1	6	7
Cyclin-dependent kinase 12	0	0	6	6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	5	5
Serine/threonine-protein kinase 26	0	0	6	6
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	0	6	6
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	7
Serine/threonine-protein kinase TBK1	0	0	6	6
Septin-9	0	0	6	6
Ribosomal protein S6 kinase alpha-6	0	0	6	6
TRAF2 and NCK-interacting protein kinase	0	0	6	6
Serine/threonine-protein kinase TAO2	0	0	6	6
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
Serine/threonine-protein kinase ICK	0	0	6	6
RAC-gamma serine/threonine-protein kinase	0	0	6	6
Serine/threonine-protein kinase SIK3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 2	0	0	6	6
Thyroid hormone receptor-associated protein 3	0	0	6	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	6	6
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	6	6
Receptor-interacting serine/threonine-protein kinase 3	0	1	6	7
Serine/threonine-protein kinase MRCK beta	0	0	6	6
Interleukin-1 receptor-associated kinase 3	0	0	6	6
Serine/threonine-protein kinase 24	0	0	5	5
Casein kinase I isoform gamma-3	0	0	6	6
Mitogen-activated protein kinase kinase kinase 4	0	0	6	6
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
USP1 protein, partial	28	0	0	28
mitogen-activated protein kinase 1	17	0	0	17
Vitamin D-binding protein	0	0	1	1
Vitamin D3 receptor	0	2	3	9
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	3	5
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Solute carrier family 22 member 6	0	15	0	22
Solute carrier family 22 member 7	0	3	0	7
Solute carrier family 22 member 8	0	14	0	22
Solute carrier family 22 member 11	0	6	0	11
Solute carrier family 22 member 8	0	12	0	18
Solute carrier family 22 member 7	0	4	0	7
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
67.9K protein	19	0	0	19
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	7	0	0	7
thyrotropin-releasing hormone receptor	2	0	0	2
Caspase-2	0	0	1	1
Inositol monophosphatase 1	6	0	0	6
Luciferase	19	0	0	19
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	8	0	13
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
PAX8	0	0	0	2
glp-1 receptor, partial	11	0	0	11
PINK1	1	0	0	1
Parkin	5	0	0	5
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
cytochrome P450 2D6 isoform 1	9	0	0	9
hepatocyte nuclear factor 4-alpha isoform 2	0	2	0	2
cytochrome P450 2C9 precursor	9	0	0	9
perilipin-5	0	3	0	3
perilipin-1	0	3	0	3
huntingtin isoform 2	6	0	0	6
importin subunit beta-1 isoform 1	6	0	0	6
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
protein AF-9 isoform a	0	0	0	1
snurportin-1	6	0	0	6
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
bcl-2-related protein A1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	3	0	3
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	7	0	10
Solute carrier family 22 member 1	0	9	0	11
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	0	0	10
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	5	0	6
Glutathione reductase, mitochondrial	0	3	0	4
72 kDa type IV collagenase	0	5	0	5
Trypanothione reductase	0	3	0	3
Alpha-synuclein	6	4	0	10
Histamine H2 receptor	18	2	2	22
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	4	0	4
Rap guanine nucleotide exchange factor 4	3	0	0	3
Multidrug and toxin extrusion protein 1	0	8	0	8
Spermine oxidase	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
neuropeptide S receptor isoform A	10	0	0	10
60 kDa chaperonin	0	5	0	5
Glycine receptor subunit alpha-1	0	0	3	3
Glutamine synthetase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
ATP-dependent translocase ABCB1	0	11	2	18
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Histamine H2 receptor	0	7	2	9
Histamine H1 receptor	0	1	5	6
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	3	0	3
Solute carrier family 22 member 1	0	8	0	10
Histamine H4 receptor	0	3	2	5
Solute carrier family 22 member 2	0	7	0	8
Solute carrier family 22 member 4	0	1	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Adenosine receptor A3	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	2	0	2
Stromelysin-1	0	3	1	4
Macrophage metalloelastase	0	1	0	1
endonuclease IV	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
Tubulin alpha-1A chain	0	2	2	5
Tubulin beta chain	0	2	2	4
Plasma kallikrein	0	0	0	3
Tubulin beta-4A chain	0	3	3	8
Tubulin beta chain	0	3	3	8
Tubulin alpha-3C chain	0	3	3	8
Tubulin alpha-1B chain	0	3	3	8
Tubulin alpha-4A chain	0	3	3	8
Tubulin beta-4B chain	0	3	3	8
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	4	3	9
Tubulin beta-2A chain	0	3	3	8
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	3	8
Tubulin beta-2B chain	0	2	1	5
Tubulin alpha-3E chain	0	3	3	8
Tubulin alpha-1A chain	0	3	3	8
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	3	3	8
Tubulin beta-6 chain	0	3	3	8
Tubulin beta-2B chain	0	3	3	8
Tubulin beta-1 chain	0	3	3	8
nonstructural protein 1	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	0	2	2	4
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	7	0	12
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
dopamine D1 receptor	3	0	0	3
regulator of G-protein signaling 4	12	0	0	12
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	5	0	6
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	2	2	4
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	5	0	9
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	3	0	5
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	2
Deoxynucleoside kinase	0	1	0	1
Pirin	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	1	4	5
Cyclin-dependent kinase-like 5	0	0	4	4
GTPase KRas	0	2	0	2
RAF proto-oncogene serine/threonine-protein kinase	0	2	3	7
Tyrosine-protein kinase Fgr	0	0	5	5
DNA topoisomerase 2-alpha	0	0	4	5
Ephrin type-A receptor 1	0	0	5	5
Serine/threonine-protein kinase receptor R3	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	2	2
Heat shock factor protein 1	0	2	0	2
Tyrosine-protein kinase Mer	0	1	5	6
Receptor-interacting serine/threonine-protein kinase 1	0	1	2	3
Cyclin-dependent kinase 10	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	4	4
MAP kinase-activated protein kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	4	4
Serine/threonine-protein kinase N3	0	0	5	5
Dual serine/threonine and tyrosine protein kinase	0	1	2	3
Misshapen-like kinase 1	0	0	4	4
PAS domain-containing serine/threonine-protein kinase	0	0	4	4
Dual specificity testis-specific protein kinase 2	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	4	4
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Transthyretin	0	1	1	3
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	5	0	10
Reverse transcriptase/RNaseH	0	2	2	7
serine/threonine-protein kinase PLK1	4	0	0	4
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
5-hydroxytryptamine receptor 4	0	4	0	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	5	0	5
Beta-1 adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	7	1	8
Adenosine receptor A3	0	7	0	7
Muscarinic acetylcholine receptor M1	0	6	0	6
D(2) dopamine receptor	0	4	1	5
Alpha-1B adrenergic receptor	0	9	0	9
Alpha-2C adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M3	0	6	0	6
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	4	0	4
Thromboxane-A synthase	0	3	0	3
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	4	0	4
Adenosine receptor A1	0	5	0	5
Sodium-dependent serotonin transporter	0	4	0	4
Mu-type opioid receptor	0	7	2	10
D(3) dopamine receptor	0	7	0	7
Vasopressin V1a receptor	0	2	0	2
Delta-type opioid receptor	0	9	1	11
Kappa-type opioid receptor	0	7	1	9
5-hydroxytryptamine receptor 2B	0	10	0	10
Alpha-1A adrenergic receptor	0	9	0	9
5-hydroxytryptamine receptor 6	0	7	0	7
Estrogen-related receptor gamma	0	0	1	1
Sodium-dependent dopamine transporter	0	2	0	2
UDP-glucose 4-epimerase	0	2	0	2
Estrogen receptor beta	0	5	2	8
Cysteinyl leukotriene receptor 1	0	2	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	6
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	5
Eyes absent homolog 2	0	2	0	2
Amyloid-beta precursor protein	0	3	0	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	5	0	10
ATP-binding cassette sub-family C member 3	0	1	0	4
Solute carrier family 22 member 8	0	2	0	5
Solute carrier organic anion transporter family member 1A3	0	4	0	9
ATP-binding cassette sub-family C member 10	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	5	0	9
ATP-binding cassette sub-family C member 11	0	0	0	2
Multidrug resistance associated protein	0	2	0	6
Solute carrier organic anion transporter family member 1C1	0	5	0	5
Solute carrier organic anion transporter family member 1A1	0	0	0	3
Solute carrier organic anion transporter family member 1B1	0	11	0	17
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Rap guanine nucleotide exchange factor 3	5	0	0	5
Aromatase	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Cytochrome P450 1B1	0	2	0	2
Ghrelin O-acyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	2
Solute carrier organic anion transporter family member 2B1	0	4	0	8
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	4
Estrogen receptor	0	0	0	2
Sodium/bile acid cotransporter	0	1	0	4
Solute carrier organic anion transporter family member 1A2	0	0	0	4
Solute carrier organic anion transporter family member	0	0	0	2
Chain A, GLUTATHIONE TRANSFERASE A1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain B, Glutathione S-transferase P1-1	0	1	0	1
Nrf2	1	0	0	1
WRN	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
Hematopoietic prostaglandin D synthase	0	1	0	1
Glutathione S-transferase A1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	2	1	3
Guanine nucleotide-binding protein G	4	0	0	4
Glutathione S-transferase omega-1	0	1	0	1
14 kDa phosphohistidine phosphatase	0	2	0	2
large T antigen	0	1	0	1
Dihydrofolate reductase	0	8	0	9
Amine oxidase [flavin-containing] A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Kappa-type opioid receptor	0	4	1	6
Histamine H1 receptor	0	5	2	7
Mu-type opioid receptor	0	3	1	6
D(1A) dopamine receptor	5	0	0	5
Cocaine esterase	0	2	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Leukotriene C4 synthase	0	0	2	2
epidermal growth factor receptor isoform a precursor	1	1	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	2	3
Serine/threonine-protein kinase 25	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Mitogen-activated protein kinase 13	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
NUAK family SNF1-like kinase 1	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Cyclin-dependent kinase 14	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	2	2
Serine/threonine-protein kinase Chk2	0	0	2	2
Receptor tyrosine-protein kinase erbB-2	0	2	2	4
Cytochrome P450 2E1	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	0	2	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	1	2	3
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
Sodium-dependent dopamine transporter	0	4	0	4
Protein kinase C eta type	0	0	2	2
Cruzipain	0	1	0	1
Activin receptor type-2A	0	0	2	2
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Leukocyte tyrosine kinase receptor	0	0	2	2
Mitogen-activated protein kinase 4	0	0	2	2
G protein-coupled receptor kinase 4	0	0	2	2
Type-1 angiotensin II receptor	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	2	3
Serine/threonine-protein kinase mTOR	0	2	3	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase TXK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	3	3
Tyrosine-protein kinase ZAP-70	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	2	3
Cyclin-dependent kinase 8	0	0	2	2
Tyrosine-protein kinase Blk	0	0	2	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	3	2	5
Death-associated protein kinase 1	0	0	2	2
Mitogen-activated protein kinase 12	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	3
Ephrin type-B receptor 1	0	0	2	2
Beta-secretase 1	0	1	0	1
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Cell division control protein 2 homolog	0	0	2	2
Calcium-dependent protein kinase 1	0	0	2	2
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Synaptic vesicular amine transporter	0	1	0	1
Protein kinase C epsilon type	0	1	2	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Serine/threonine-protein kinase PAK 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Serine/threonine-protein kinase D1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Cyclin-dependent kinase 15	0	0	2	2
SRSF protein kinase 1	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	2	2
Serine/threonine-protein kinase PLK2	0	0	2	2
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	2	2
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
SRSF protein kinase 3	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	3
Amino acid transporter	0	3	0	3
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	6
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	5
Glutamate receptor ionotropic, NMDA 2C	0	2	1	5
Large neutral amino acids transporter small subunit 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	2	1	5
Glutamate receptor ionotropic, NMDA 3B	0	2	1	5
Serine racemase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	1	5
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Histamine H3 receptor	0	1	2	3
ClpP	2	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	3	0	3
Acid-sensing ion channel 3	0	1	0	1
Albumin	0	3	5	10
Albumin	0	0	1	1
Cholinesterase	0	2	0	2
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	7
UDP-glucuronosyltransferase 2B7	0	2	0	5
Prostaglandin G/H synthase 1	0	2	0	2
Caspase-1	0	2	0	3
Prostaglandin G/H synthase 2	0	4	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	3
Aldo-keto reductase family 1 member C3	0	4	0	4
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Prostaglandin G/H synthase 1	0	4	0	6
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Oxysterols receptor LXR-beta	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Replicase polyprotein 1ab	0	3	1	4
Gag-Pol polyprotein	0	2	0	2
Alpha-1D adrenergic receptor	0	4	0	4
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Protease	0	3	2	7
Protease	0	2	1	3
Protease	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Procathepsin L	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Interleukin-8	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	0	1	1
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	4	0	4
Muscarinic acetylcholine receptor M5	0	4	0	4
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	1	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cereblon isoform 4	0	4	0	4
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Protein cereblon	0	5	2	10
Zinc finger protein Aiolos	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Phospholipase A-2-activating protein	0	2	0	2
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	1	3
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Proton-coupled folate transporter	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Lanosterol 14-alpha demethylase	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Hormone-sensitive lipase	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
pyruvate kinase PKM isoform b	1	0	0	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Ornithine decarboxylase	1	0	0	2
Transcription factor SOX-18	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Transcriptional enhancer factor TEF-3	0	1	1	2
Neuropeptide FF receptor 2	0	0	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Integrin alpha-V	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Beta-tubulin	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	3	0	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain A, phosphoenolpyruvate carboxykinase, cytosolic	0	1	0	1
Chain A, Phosphoenolpyruvate Carboxykinase, Cytosolic	0	1	0	1
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	0	1	0	1
DNA polymerase III, partial	1	0	0	1
XBP1	0	1	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Serine/threonine-protein kinase ATR	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Glutamate 5-kinase	0	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
N	0	1	0	1
NPYLR7B	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
NS5	0	0	2	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Transmembrane protease serine 2	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
Butyrophilin subfamily 3 member A1	0	0	2	3
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	2	0	2
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
RNA-directed RNA polymerase	0	1	2	4
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Protein argonaute-2	0	0	1	1
Ileal sodium/bile acid cotransporter	0	2	0	3
Sodium/bile acid cotransporter	0	2	0	3
Chain A, Prostatic Acid Phosphatase	0	1	0	1
Sodium/bile acid cotransporter	0	0	0	1
Ileal sodium/bile acid cotransporter	0	0	0	1
Ileal sodium/bile acid cotransporter	0	0	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4A1	0	0	0	2
Solute carrier organic anion transporter family member 2B1	0	0	0	1
Bile salt export pump	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	3
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	2	0	4
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	1	0	3
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Thyroid hormone receptor alpha	0	2	2	4
Thyroid hormone receptor beta	0	2	2	4
Proliferating cell nuclear antigen	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
pyruvate kinase PKM isoform a	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (493)

Protein Targets (1,914)

Osteosclerosis

Synonyms(1)

Research Excerpts

Overview

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Research

Studies (493)

Drugs Studied (253)

Protein Targets (1,914)