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buffer
Any substance or mixture of substances that, in solution (typically aqueous), resists change in pH upon addition of small amounts of acid or base.
ChEBI ID: 35225
Members (9)
Member | Definition | Class |
1,3-bis(tris(hydroxymethyl)methylamino)propane | A water-soluble buffer substance used for the preparation of the biochemical and biological buffer solutions; pKa = 6.8 at 20 degreeC. | bis-tris propane |
ammonium acetate | An ammonium salt obtained by reaction of ammonia with acetic acid. A deliquescent white crystalline solid, it has a relatively low melting point (114degreeC) for a salt. Used as a food acidity regulator, although no longer approved for this purpose in the EU. | ammonium acetate |
ammonium citrate | A citrate salt in which all three carboxy groups are deprotonated and associated with ammonium ions as counter-cations. | triammonium citrate |
bistris | A buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 degreeC. | bis-tris |
diisopropanolamine | A secondary amino compound that is diethanolamine substituted by methyl groups at positions 1 and 1'. It is a versatile chemical used in a variety of personal care, cosmetic and industrial products. | diisopropanolamine |
formic acid, sodium salt | An organic sodium salt which is the monosodium salt of formic acid. | sodium formate |
potassium bicarbonate | A potassium salt that is the monopotassium salt of carbonic acid. It has fungicidal properties and is used in organic farming for the control of powdery mildew and apple scab. | potassium hydrogencarbonate |
triethanolamine | A tertiary amino compound that is ammonia in which each of the hydrogens is substituted by a 2-hydroxyethyl group. | triethanolamine |
tromethamine | A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC. | tris |
Research
Studies (4,593)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 2,078 (45.24) | 18.7374 |
1990's | 850 (18.51) | 18.2507 |
2000's | 734 (15.98) | 29.6817 |
2010's | 757 (16.48) | 24.3611 |
2020's | 174 (3.79) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 323 (6.58%) | 5.53% |
Reviews | 127 (2.59%) | 6.00% |
Case Studies | 116 (2.36%) | 4.05% |
Observational | 2 (0.04%) | 0.25% |
Other | 4,344 (88.44%) | 84.16% |
Protein Targets (26)
Potency Measurements
Inhibition Measurements