| Excerpt | Reference |
|---|
| "Congenital afibrinogenemia is a rare hereditary disorder which has been described in only 150 families." | ( Gitel, S; Levi, Y; Martinowitz, U; Ra'anani, P; Varon, D, 1991) |
| "Congenital afibrinogenemia is a rare disorder with unusual clinical manifestations." | ( al-Mondhiry, H; Ehmann, WC, 1994) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of detectable fibrinogen." | ( Antonarakis, SE; Honsberger, A; Morris, MA; Neerman-Arbez, M, 1999) |
| "Congenital afibrinogenemia is a rare autosomal recessive hemostatic disorder leading to unclottable global coagulation tests." | ( Furlan, M; Lämmle, B; Peter, K, 1999) |
| "Congenital afibrinogenaemia is an autosomal recessive disorder characterised by the complete absence of detectable fibrinogen." | ( Antonarakis, SE; Honsberger, A; Morris, MA; Neerman-Arbez, M, 1999) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen." | ( Asselta, R; Duga, S; Malcovati, M; Mannucci, PM; Santagostino, E; Simonic, T; Tenchini, ML; Zeinali, S, 2000) |
| "Congenital afibrinogenemia is a rare, autosomal, recessive disorder characterized by the complete absence of detectable fibrinogen." | ( Antonarakis, SE; Bridel, C; Claeyssens, S; d'Oiron, R; de Moerloose, P; Di Michele, D; Dieval, J; Dreyfus, M; Honsberger, A; Laubriat-Bianchin, M; Morris, MA; Neerman-Arbez, M; Peerlinck, K; Rossier, C; Schönbörner, A, 2000) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of plasma fibrinogen and by a bleeding tendency ranging from mild to moderately severe." | ( Asselta, R; Duga, S; Giangrande, PL; Malcovati, M; Mannucci, PM; Santagostino, E; Simonic, T; Tenchini, ML, 2000) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by a hemorrhagic diathesis of variable severity." | ( Colaizzo, D; De Lucia, D; Di Minno, G; Fortina, P; Grandone, E; Lupone, MR; Margaglione, M; Perricone, C; Santacroce, R; Seripa, D; Vecchione, G, 2000) |
| "Congenital afibrinogenemia is an autosomal recessive disorder characterized by the complete absence of detectable fibrinogen." | ( Antonarakis, SE; Arnuti, B; Biron, C; Borg, JY; d'Oiron, R; de Moerloose, P; Eber, S; Honsberger, A; Meili, E; Morris, MA; Neerman-Arbez, M; Parlier, G; Peter-Salonen, K; Ripoll, L; Staeger, P; Vervel, C, 2001) |
| "Congenital afibrinogenemia is a rare coagulation disorder with autosomal recessive inheritance, characterized by the complete absence or extremely reduced levels of fibrinogen in patients' plasma and platelets." | ( Asselta, R; Duga, S; Malcovati, M; Mannucci, PM; Peyvandi, F; Piseddu, G; Santagostino, E; Spena, S; Targhetta, R; Tenchini, ML, 2001) |
| "Congenital afibrinogenemia is a rare coagulation disorder whose molecular basis is still poorly characterized." | ( Asselta, R; Duga, S; Malcovati, M; Mannucci, PM; Peyvandi, F; Spena, S; Tenchini, ML, 2002) |
| "Congenital afibrinogenemia is a rare inherited coagulopathy, characterized by very low or unmeasurable plasma levels of immunoreactive fibrinogen." | ( Asselta, R; Duga, S; Malcovati, M; Peyvandi, F; Spena, S; Tenchini, ML, 2002) |
| "Congenital afibrinogenemia is a rare autosomal recessive disease caused by markedly reduced or absent synthesis of fibrinogen." | ( Rabesiaka, F; Rakotoarimanana, DR; Rakotomalala, S; Ramialiharisoa, A; Rasamoelisoa, JM; Tovone, XG, 1999) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of detectable fibrinogen." | ( Abu-Libdeh, B; Bouchardy, I; Morris, MA; Neerman-Arbez, M; Vu, D, 2003) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by complete absence of detectable fibrinogen." | ( Bolton-Maggs, PH; de Moerloose, P; Morris, MA; Neerman-Arbez, M; Parr, JR; Vu, D, 2003) |
| "Congenital afibrinogenaemia is a rare autosomal recessive coagulation disorder." | ( Bai, X; Dong, N; Ruan, C; Wang, Z; Wu, S, 2005) |
| "Congenital afibrinogenemia is a rare bleeding disorder characterized by the absence in circulation of fibrinogen, a hexamer composed of two sets of three polypeptides (Aalpha, Bbeta and gamma)." | ( Caille, D; de Moerloose, P; Di Sanza, C; Meda, P; Neerman-Arbez, M; Scheib, H; Vu, D, 2005) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder, characterized by the complete absence or extremely reduced level of fibrinogen." | ( Dai, J; Fang, Y; Fu, QH; Wang, HL; Wang, WB; Wang, XF; Wang, ZY; Xie, S; Zhou, RF, 2005) |
| "Congenital afibrinogenaemia is a rare autosomal recessive disorder, characterized by the complete absence or extremely reduced level of fibrinogen (Fg)." | ( Cai, XH; Dai, BT; Dai, J; Fang, Y; Fu, QH; Wang, HL; Wang, XF; Wang, ZY; Xie, F, 2006) |
| "Congenital afibrinogenaemia is a rare bleeding disorder characterized by absence of fibrinogen and varying bleeding tendency." | ( Dolan, G; Garipidou, V; Hill, M; Lefkou, E; Perifanis, V; Rizopoulou, D; Tziomalos, K; Vakalopoulou, S; Zafiriadou, E, 2006) |
| "Congenital afibrinogenemia is characterized by the complete absence of fibrinogen, the precursor of the major protein constituent of the blood clot, fibrin." | ( de Moerloose, P; Neerman-Arbez, M, 2007) |
| "Congenital afibrinogenemia is a rare coagulopathy characterized by extremely low levels of functional and immunoreactive fibrinogen in plasma, associated with a hemorrhagic phenotype of variable severity." | ( Asselta, R; Duga, S; Peyvandi, F; Platé, M; Tenchini, ML, 2007) |
| "Fibrinogen deficiency is a cause for massive haemorrhage whose management in emergency situations is the subject of debate." | ( Bueno, SR; Cuenca, LG; Danés, AF; Mendarte Barrenechea, L; Ronsano, JBM, 2008) |
| "Congenital afibrinogenemia is characterized by the absence of fibrinogen, a hexamer composed of two copies of three polypeptides, Aalpha." | ( Di Sanza, C; Neerman-Arbez, M; Vu, D, 2008) |
| "Congenital afibrinogenemia is a rare disorder characterized by the absence in circulating fibrinogen, a hexamer composed of two sets of three polypeptides (Aalpha, Bbeta and gamma)." | ( de Mazancourt, P; Dinc, A; Erdem, H; Horellou, MH; Pay, S; Samama, MM; Simsek, I, 2008) |
| "Congenital hypofibrinogenemia is a rare condition." | ( Anderson, BJ; Clarson, M; Mundy, JA; Sanders, LH; Shehatha, J, 2009) |
| "Congenital afibrinogenemia is a rare coagulation disorder attributed to over forty mutations found either in homozygosity or in compound heterozygosity, the majority localized in FGA encoding the fibrinogen Aalpha-chain." | ( Abdel Wahab, M; de Moerloose, P; Fish, RJ; Neerman-Arbez, M, 2010) |
| "Congenital afibrinogenemia is a very rare inherited coagulation disorder, characterized by virtual absence of plasma fibrinogen (factor I)." | ( Hariharan, G; Parapurath, R; Ramachandran, S, 2010) |
| "Congenital hypofibrinogenemia is a rare autosomal bleeding disorder, either recessive or dominant, characterized by a low fibrinogen plasma level." | ( Dyr, JE; Hrachovinová, I; Kotlín, R; Kvasnicka, J; Malý, M; Oravec, M; Reicheltová, Z; Riedel, T; Salaj, P; Suttnar, J, 2010) |
| "Congenital afibrinogenemia is a rare autosomal recessive coagulation disorder characterized essentially by bleeding symptoms, but miscarriages and, paradoxically, thromboembolic events can also occur." | ( Aboukhamis, I; Chamaa, S; de Moerloose, P; Farho, J; Fort, A; Levrat, E; Neerman-Arbez, M; Reber, G, 2011) |
| "Congenital afibrinogenemia is characterized by the complete absence of fibrinogen, the precursor of the major protein constituent of the blood clot, fibrin." | ( Alson, OR; de Moerloose, P; Neerman-Arbez, M; Tirefort, Y, 2012) |
| "Congenital fibrinogen deficiency is a rare bleeding disorder, affecting either the quantity (afibrinogenemia, hypofibrinogenemia) or quality (dysfibrinogenemia) of circulating fibrinogen." | ( Peyvandi, F, 2012) |
| "Congenital hypofibrinogenemia is a rare disorder caused by heterozygous mutations in one of the three fibrinogen genes--fibrinogen α-chain (FGA), fibrinogen β-chain (FGB) and fibrinogen γ-chain (FGG)--which code for the Aα, Bβ and γ chains, respectively." | ( Jin, Y; Wang, M; Xie, H; Xu, P; Yang, L; Zhu, L, 2013) |
| "Congenital fibrinogen deficiency is an extremely rare (1:1 000 000) hereditary bleeding disorder caused by defects in genes coding for fibrinogen Aα-, Bβ- and γ-chains, respectively." | ( Abraham, A; Arora, N; Chandy, M; David, S; Devi, GS; George, B; Jayandharan, GR; Mathews, V; Nair, SC; Shenbagapriya, P; Srivastava, A; Sumitha, E; Viswabandya, A, 2013) |
| "Congenital afibrinogenaemia is a rare autosomal recessive disorder caused by various mutations within the fibrinogen genes FGA, FGB and FGG." | ( Bai, X; Cao, L; Ruan, C; Wang, Z; Yu, Z; Zhang, J; Zhang, W; Zhao, X, 2013) |
| "Congenital hypofibrinogenemia is a rare disorder caused by heterozygous mutations in the fibrinogen genes." | ( Ding, H; Hao, X; Wang, M; Wang, Y; Xie, H; Xie, Y; Zhao, M; Zhu, L, 2014) |
| "Congenital afibrinogenemia is a rare inherited autosomal recessive disorder in which a mutation in one of three genes coding for the fibrinogen polypeptide chains Aα, Bβ and γ results in the absence of a functional coagulation protein." | ( Banz, V; Candinas, D; Demarmels Biasiutti, F; Fort, A; Furer, C; Keogh, A; Kühni-Boghenbor, K; Lämmle, B; Neerman-Arbez, M; Stoffel, MH; Stroka, D; Vu, D, 2014) |
| "Although congenital afibrinogenemia is a rare autosomal recessive bleeding disorder, it can be more frequently encountered in countries where consanguineous marriages are common." | ( Işik, B; Karakukcu, M; Mutlu, FT; Ozdemir, MA; Patiroglu, T; Unal, E; Yilmaz, E, 2015) |
| "In particular, congenital afibrinogenemia is inherited as an autosomal recessive mode and is usually determined by homozygous or compound heterozygous mutations affecting any of the three fibrinogen genes (FGA, FGB and FGG), resulting in the complete absence or extremely reduced amount of fibrinogen." | ( Amri, Y; de Moerloose, P; Hadj Fredj, S; Toumi, Nel H, 2016) |
| "Congenital fibrinogen deficiency is an autosomal recessive or dominant disorder in which quantitative (afibrinogenaemia or hypofibrinogenaemia) or qualitative (dysfibrinogenaemia) defects in the fibrinogen Aa, Bb or c protein chains that lead to reduced functional fibrinogen." | ( Li, CQ; Wang, DX; Wei, XY, 2018) |
| "Congenital hypofibrinogenemia is a type of hereditary disease characterized by impaired fibrinogen synthesis and/or secretion induced by mutations in the fibrinogen gene." | ( Cheng, P; Deng, D; Deng, X; Liao, L; Lin, F; Luo, M; Wei, A; Xiang, L; Yan, J; Zhou, W, 2018) |
| "Acquired fibrinogen deficiency is a major determinant of severe bleeding in different clinical conditions, including cardiac surgery, trauma, postpartum hemorrhage, liver surgery, and transplantation." | ( Baryshnikova, E; Di Dedda, U; Ranucci, M, 2020) |
| "Congenital afibrinogenemia is characterized by the absence of fibrinogen." | ( Akbas, Y; Aydin Köker, S; Coban, Y; Kara, TT; Köker, A; Neerman-Arbez, M; Ö Tunçer, G, 2020) |
| "Congenital afibrinogenemia is a rare coagulation disease." | ( Akbas, Y; Aydin Köker, S; Coban, Y; Kara, TT; Köker, A; Neerman-Arbez, M; Ö Tunçer, G, 2020) |
| "Congenital fibrinogen deficiency is an ultra-rare disorder in which patients can experience severe and/or frequent bleeding episodes (BEs)." | ( Almomen, A; D'Souza, F; De Angulo, GR; Djambas Khayat, C; Hoorfar, H; Karimi, M; Kavakli, K; Knaub, S; Lissitchkov, T; Madan, B; Peyvandi, F; Ross, C; Schwartz, BA; Solomon, C; Subramanian, K; Viswabandya, A; Zozulya, N, 2020) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen." | ( Akar, N; Özkan, DT; Sarper, N, 2020) |
| "Congenital afibrinogenemia is a rare disorder characterized by a lack of detectable fibrinogen." | ( Conneely, S; Hsieh, E; Lee-Kim, Y; Miller, J; Nicholas, S; Teruya, J, 2021) |
| "Congenital fibrinogen deficiency is one of the rare inherited coagulation disorders." | ( Akyol, Ş; Erdoğmuş, NA; Karakükçü, M; Özcan, A; Patıroğlu, T; Samur, B; Ünal, E, 2020) |
| "Congenital afibrinogenemia is a severe bleeding disorder, sometimes manifesting as thrombosis and/or pregnancy complications." | ( Iwaniec, T; Neerman-Arbez, M; Undas, A; Vilar, R; Wypasek, E; Zdziarska, J, 2021) |
| "Congenital afibrinogenemia is a rare autosomal recessive disorder that is caused by defects in the fibrinogen." | ( Amini, M; Masoodifard, M; Mojbafan, M; Nojehdeh, ST; Zeinali, S, 2021) |
| "Congenital fibrinogen deficiency is an inherited disorder due to genetic mutations with diverse presentations arising from reduced fibrinogen levels (hypofibrinogenemia), absence of fibrinogen in circulation (afibrinogenemia), abnormal functioning (dysfibrinogenemia) or both reduced levels and abnormal functioning (hypodysfibrinogenemia) of fibrinogen." | ( Byreddy, P; John, MJ; Makkar, M; Modak, K, 2021) |
| "Congenital afibrinogenemia is the most severe congenital fibrinogen disorder, characterized by undetectable fibrinogen in circulation." | ( Casini, A; Di Sanza, C; Guipponi, M; Malbora, B; Masclaux, F; Menegatti, M; Neerman-Arbez, M; Özbek, N; Peyvandi, F; Sloan-Béna, F, 2022) |
| "Congenital afibrinogenemia is an autosomal recessive inherited disorder that can cause thrombotic as well as hemorrhagic events." | ( Araki, Y; Goto, S; Hattori, M; Izumi, T; Matsushita, T; Nishihori, M; Saito, R; Suzuki, N; Tamura, S; Uda, K; Yokoyama, K, 2022) |