A ketone of formula RC(=O)CH3 (R =/= H).
| Member | Definition | Role |
|---|
| 1-hydroxy-1-phenyl-2-propanone | A secondary alpha-hydroxy ketone that is benzene which is substituted by a 1-hydroxy-2-oxopropyl group at position 1. | 1-hydroxy-1-phenylpropan-2-one |
| 1-phenyl-2-propanone | A propanone that is propan-2-one substituted by a phenyl group at position 1. | phenylacetone |
| 2-acetyl-1-pyrroline | A pyrroline that is 1-pyrroline in which the hydrogen at position 2 is replaced by an acetyl group. It is an aroma and flavour compound present in jasmine rice and basmati rice. It is responsible for the 'popcorn' aroma in a large variety of cereal and food products. It is one of the key odourants of the crust of bread and considered to be responsible for the cracker-like odour properties. In bread, it is primarily generated during baking but amounts are influenced by ingredient composition and fermentation conditions. | 2-acetyl-1-pyrroline |
| 2-acetylfuran | A furan carrying an acetyl substituent at the 2-position. Used in the production of the antibiotic cefuroxime (CHEBI:3515). | 2-acetylfuran |
| 2-acetylpyrrole | A pyrrole carrying an acetyl substituent at the 2-position. | 2-acetylpyrrole |
| 2-amino-4-oxo-6-acetyl-7,8-dihydro-3h,9h-pyrimidodiazepine | A member of the class of pyrimidodiazepine 3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one bearing amino and acetyl substituents at positions 2 and 6 respectively. | 6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one |
| 2-heptanone | A dialkyl ketone with methyl and pentyl as the alkyl groups. | heptan-2-one |
| 2-nonanone | A methyl ketone that is nonane in which the methylene hydrogens at position 2 are replaced by an oxo group. | nonan-2-one |
| 2-octanone | A methyl ketone that is octane substituted by an oxo group at position 2. | 2-octanone |
| 2-pentanone | A pentanone carrying an oxo substituent at position 2. | pentan-2-one |
| 2-tridecanone | A methyl ketone that is tridecane in which the methylene hydrogens at position 2 are replaced by an oxo group. | tridecan-2-one |
| 2,3-pentanedione | An alpha-diketone that is pentane substituted at the 2- and 3-positions by oxo groups. | pentane-2,3-dione |
| 2,4-diacetylphloroglucinol | A benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups. | 2,4-diacetylphloroglucinol |
| 2,4,6-trihydroxyacetophenone | A benzenetriol that is acetophenone in which the hydrogens at positions 2, 4, and 6 on the phenyl group are replaced by hydroxy groups. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of acidic glycans and glycopeptides. | 2',4',6'-trihydroxyacetophenone |
| 2,5-hexanedione | A diketone that is hexane substituted by oxo groups at positions 2 and 5. It is a toxic metabolite of hexane and of 2-hexanone | 2,5-hexanedione |
| 3-buten-2-one | A methyl ketone that is butan-2-one with an unsaturation at position 3. | buten-2-one |
| 4-methyl-4-sulfanylpentan-2-one | An alkylthiol that is 4-methylpentan-2-one substituted at position 4 by a mercapto group. | 4-mercapto-4-methylpentan-2-one |
| acenocoumarol | A hydroxycoumarin that is warfarin in which the hydrogen at position 4 of the phenyl substituent is replaced by a nitro group. | acenocoumarol |
| acepromazine | A member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. | acepromazine |
| acetoin | A methyl ketone that is butan-2-one substituted by a hydroxy group at position 3. | acetoin |
| acetol | A propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group. | hydroxyacetone |
| acetone | A methyl ketone that consists of propane bearing an oxo group at C2. | acetone |
| acetovanillone | An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3. | apocynin |
| alpha-ionone | | alpha-ionone |
| alpha-irone | A methyl ketone that is alpha-ionone in which a hydrogen at position 5 of the cyclohex-2-en-1-yl ring is substituted by a methyl group. | alpha-irone |
| aminoacetone | A propanone consisting of acetone having an amino group at the 1-position. | aminoacetone |
| amrubicin | A synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol. | amrubicin |
| cblc137 | A member of the class of carbazoles that is 9H-carbazole which is substituted by acetyl groups at positions 3 and 6, and by a 2-isopropylethyl group on the nitrogen atom (position 9). It is a modulator of histone chaperone FACT (FAcilitates Chromatin Transcription) - interaction of CBL0137 with the FACT complex results in simultaneous NF-kappa beta suppression, Heat Shock Transcription Factor 1 (HSF1) suppression and p53 activation - and shows antitumour effects in animal models of various cancers. | CBL0137 |
| cercosporamide | A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. | cercosporamide |
| hp 873 | A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia. | iloperidone |
| kebuzone | A pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group. | kebuzone |
| knipholone | An anthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 4 and 6, a methyl group at position 2 and a 3-acetyl-2,6-dihydroxy-4-methoxyphenyl group at position 1. It exhibits antioxidant, cytotoxic and antiplasmodial activities. | knipholone |
| methylethyl ketone | A dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position C-2. | butan-2-one |
| mono(2-ethyl-5-oxohexyl)phthalate | A phthalic acid monoester obtained by formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of 2-ethyl-5-oxohexan-1-ol. | mono(2-ethyl-5-oxohexyl) phthalate |
| nabumetone | A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs. | nabumetone |
| pinacolone | A methyl ketone that is butane substituted by an oxo group at position 2 and two methyl groups at position 3. | 3,3-dimethylbutan-2-one |
| platanic acid | A pentacyclic triterpenoid that is 30-norlupan-28-oic acid substituted by a 3beta-hydroxy and an oxo group at position 20. It is isolated from the leaves of Syzygium claviflorum and exhibits anti-HIV activity. | platanic acid |
| raspberry ketone | A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics. | raspberry ketone |
| rottlerin | A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis. | rottlerin |
| undecan-2-one | A dialkyl ketone with methyl and nonyl as the two alkyl groups. | undecan-2-one |
| usnic acid | A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b. | usnic acid |
| warfarin | A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one |
| zingerone | A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger. | zingerone |