tetracycline and Pneumonia

A 74-year-old woman presented with a 2-day history of cough, dyspnea and wheezing following aspiration of a tetracycline tablet. She developed a left lower lobe pneumonitis, and bronchoscopy revealed left main bronchus narrowing and exudate. The course of this patient is discussed in reference to the available literature on toxic aspirations.

Topics: Aged; Bronchi; Bronchoscopy; Female; Foreign Bodies; Humans; Inhalation; Pneumonia; Tetracycline

Chlamydia pneumoniae is the third strain of Chlamydia and transmission is presumed to be by droplet spread from symptomatic patients. The authors show a literature scientific review on subject-matter emphasizing several sporadic and epidemic case of illness in every age, first months excepted. The described cases are few and therefore clinical characteristics are shadowy. Certain clinical features are suggesting of severe pneumonia with fever and pharyngitis without exudate. In the childhood and in the adolescence the clinical evolution is favourable. Tetracyclines or erythromycin is recommended for therapy.

Topics: Age Factors; Child; Child, Preschool; Chlamydophila pneumoniae; Erythromycin; Fever; Fluorescent Antibody Technique; Humans; Infant; Infant, Newborn; Lung; Pharyngitis; Pneumonia; Tetracycline

Chlamydia pneumoniae, strain TWAR is a newly recognized third species of Chlamydia. It is an important cause of pneumonia, bronchitis, sinusitis, and other acute respiratory infections. It is a human pathogen transmitted by the respiratory route. Successful antibiotic treatment with tetracycline or erythromycin requires high dosage and a prolonged course.

Topics: Chlamydia Infections; Chlamydophila pneumoniae; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythromycin; Humans; Pneumonia; Tetracycline

The different patterns of pneumonia are classified and show the various manifestations of the disease, indicating the necessary specific diagnostic procedures. Only by description and recognition of the possible pathogenic agents, an adequate therapy can be initiated as described in the last chapter.

Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Biopsy; Cefoxitin; Cephalosporins; Clindamycin; Cross Infection; Erythromycin; Humans; Legionnaires' Disease; Lung; Metronidazole; Penicillin G; Pneumonia; Radiography, Thoracic; Serologic Tests; Sputum; Tetracycline

Topics: Clinical Laboratory Techniques; Cross Infection; Disease Outbreaks; England; Erythromycin; Humans; Legionella; Legionnaires' Disease; Pneumonia; Prognosis; Rifampin; Risk; Tetracycline; United States

Following the discovery of Legionella pneumophila as the cause of an epidemic of pneumonia at an American Legion Convention in Philadelphia, a group of related bacteria were recognized as additional human pathogens. This newly established bacteria genus, Legionella, includes the agents of Legionnaires' Disease, Pittsburgh pneumonia and several related infections. A number of researches have been performed in the past few years about these bacteria; many of these data are here summarized to give an idea of the most important characteristics of Legionella and of the diseases they cause.

Topics: Antibody Formation; Bacterial Infections; Disease Outbreaks; Erythromycin; Humans; Legionella; Legionnaires' Disease; Phenotype; Pneumonia; Postoperative Complications; Rifampin; Serotyping; Tetracycline

Nongonococcal urethritis is a venereal disease whose incidence is almost double that of gonorrhea. Despite this, the diagnosis, origin, treatment, and complications of nongonococcal urethritis remain unclear. Although some cases are undoubtedly caused by infection with Chlamydia trachomatis, the origin of many cases is uncertain. Treatment is recommended to shorten symptoms and prevent complications. This review presents the current status of this confusing disease.

Topics: Adolescent; Adult; Epididymitis; Female; Gonorrhea; Humans; Infant; Male; Mycoplasma Infections; Neisseria gonorrhoeae; Pelvic Inflammatory Disease; Pneumonia; Sexually Transmitted Diseases; Tetracycline; Trachoma; Urethritis

Legionella pneumophila infections frequently manifest themselves as a multisystem disease with acute pneumonia. Certain clinical and laboratory features are helpful in diagnosis but none are pathognomonic. Diagnosis frequently must be made clinically and erythromycin given presumptively because of the delay in seroconversion but culture and direct fluorescent antibody testing are quite useful for rapid diagnosis. Epidemiologic and laboratory investigations will undoubtedly yield considerable information about this fascinating bacterial disease.

Topics: Air Conditioning; Bacteria; Cross Infection; Disease Outbreaks; Erythromycin; Humans; Legionnaires' Disease; Pneumonia; Rifampin; Tetracycline; United States

It were Liebow et al. (1965) who, for the first time, described the desquamative interstitial pneumonia (DIP) as one clinical and morphological unit. The etiopathology of this disease is still unknown and there exist many controversial opinions as to its role within the interstitial pneumonias. For the clinical-physician the DIP represents a difficult problem because there seems to be no uniform appearance to this disease. So a lung-biopsy is the unique way to make a definitive diagnosis. The following description represents a case of DIP observed at our hospital. At the same time we tried to give a review of our present knowledge concerning the morphology, course and therapy of this disease. We think it should be note that the DIP was accompanied by an extreme peripheral eosinophilia. To our knowledge this is the first time such a phenomenon is described. In the course of the treatment with steroids the eosinophilia disappeared parallel to the normalization of the radiographic findings.

Topics: Adrenal Cortex Hormones; Adult; Alveolitis, Extrinsic Allergic; Collagen Diseases; Diagnosis, Differential; Eosinophilia; Female; Histiocytosis, Langerhans-Cell; Humans; Isoniazid; Lung; Pneumonia; Pulmonary Eosinophilia; Radiography; Rifampin; Tetracycline

Topics: Chlamydia Infections; Chlamydophila psittaci; Humans; Meningococcal Infections; Mycoplasma Infections; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Pneumonia, Staphylococcal; Pneumonia, Viral; Tetracycline

A review of the medical literature and two case reports of M. pneumoniae infections with exanthems are presented. Erythematous maculopapular and vesicular exanthems were most common. The duration of rash was more than seven days in the majority of instances, and most patients had associated pneumonia. A striking difference in prevalence and clinical symptomatology by sex was noted; 16 of 20 patients analyzed were males, and they frequently dad severe mucocutaneous syndromes. In contrast, severe conjunctivitis, generalized ulcerative stomatitis, and vesicular or bullous exanthems were not seen in females. Clinicians should suspect infection with M. pneumoniae in patients with exanthem and pneumonia, although other etiologic possibilities should also be considered.

Topics: Adolescent; Adult; Child; Child, Preschool; Complement Fixation Tests; Exanthema; Female; Humans; Male; Measles Vaccine; Mycoplasma Infections; Pneumonia; Radiography; Tetracycline

Topics: Adolescent; Adult; Aminosalicylic Acids; Bronchitis; Child; Child, Preschool; Erythromycin; Female; Haemophilus Infections; Herpesviridae Infections; Humans; Infant; Isoniazid; Male; Mycoplasma Infections; Penicillins; Pneumococcal Infections; Pneumonia; Pneumonia, Pneumocystis; Pneumonia, Staphylococcal; Pneumonia, Viral; Radiography; Respiratory Tract Infections; Skin Tests; Streptococcal Infections; Tetracycline; Tuberculosis, Pulmonary

Topics: Abortion, Spontaneous; Antibodies; Bacteriuria; Chickenpox; Chromosome Aberrations; Chromosome Disorders; Congenital Abnormalities; Coxsackievirus Infections; Cytomegalovirus; Female; Fetal Death; Fetal Diseases; Hepatitis; Herpesviridae Infections; Hormones; Humans; Influenza, Human; Maternal-Fetal Exchange; Measles; Mumps; Obstetric Labor, Premature; Pneumonia; Poliomyelitis; Pregnancy; Pregnancy Complications, Infectious; Rubella; Smallpox; Smallpox Vaccine; Syphilis; Tetracycline; Toxoplasmosis; Toxoplasmosis, Congenital

In adults hospitalized with community-acquired pneumonia (CAP) after >48 h of outpatient beta-lactam monotherapy, coverage of atypical pathogens is recommended based on expert opinion.. In a post-hoc analysis of a large study of CAP treatment we included patients who received beta-lactam monotherapy for >48 h before hospitalization. Length of hospital stay (LOS), 30-day mortality, and number of treatment escalations were compared for those that continued beta-lactam monotherapy and those that received atypical coverage at admission.. Of 179 patients (median age 66 years (IQR 50-78), 100 (56%) male), 131 (73%) received additional atypical coverage at admission. These patients were younger, had less comorbidities, and longer symptom duration, compared to those that continued beta-lactam monotherapy. In crude analysis, median (IQR) LOS was 6 (4-8) and 6 (4-9) days, mortality was 2% and 4%, and treatment escalations occurred in 8 (17%) and 11 (8%) patients without and with atypical coverage, respectively. Adjusted effect ratios for absence of atypical coverage on LOS, mortality, and treatment escalation were 0.77 (95% CI 0.61-0.97), 0.37 (0.04-3.67), and 2.75 (0.94-8.09), respectively.. In adults hospitalized with CAP after >48 h of outpatient beta-lactam monotherapy, not starting antibiotics with atypical coverage was associated with a trend towards more treatment escalations, without evidence of increased LOS or mortality.

Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Community-Acquired Infections; Drug Therapy, Combination; Female; Fluoroquinolones; Hospitalization; Humans; Length of Stay; Macrolides; Male; Middle Aged; Netherlands; Outcome Assessment, Health Care; Pneumonia; Tetracycline; Treatment Outcome

The results from the comparative clinical studies on the effectiveness of tetraolean and tetracycline are summed up about 1672 patients with acute and exacerbated infections of the respiratory organs (1036 patient, treated by ten teams, working on the theme given in advance "Comparative clinical studies between tetraolean and tetracyclin in acute pneumonia", 164 patients with postgrippe viral-bacterial pneumonia, treated during the grippe epidemy 1972/1973 and 445 patient treated at the Therapeutic Clinic, Sofia during 1967-1972). The total results reveal that, according to the adopted objective indices, the therapeutic effect of tetraolean is with a statistically significant superiority over tetracyclin. The beneficial results obtained in the treatment of 14 patients with endocarditis lenta are also reported. The mechanisms of that superior effect, defined as "clinical synergism" are discussed.

Topics: Acute Disease; Bulgaria; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Endocarditis, Subacute Bacterial; Humans; Influenza, Human; Lung Diseases; Oleandomycin; Pneumonia; Tetracycline

Topics: Adenoviridae; Adenoviridae Infections; Bacterial Infections; Clinical Trials as Topic; Humans; Influenza, Human; Lung; Minocycline; Neisseria meningitidis; Orthomyxoviridae; Paramyxoviridae Infections; Pneumonia; Pneumonia, Viral; Respiratory System; Respirovirus; Sputum; Tetracycline; Trachea

Topics: Administration, Oral; Adolescent; Adult; Antigens, Bacterial; Clindamycin; Clinical Trials as Topic; Fever; Hospitalization; Humans; Length of Stay; Lung; Male; Mycoplasma Infections; Placebos; Pneumonia; Radiography; Tetracycline

Topics: Ampicillin; Anti-Bacterial Agents; Bronchitis; Child; Chloramphenicol; Clinical Trials as Topic; Dyspnea; Female; Glycine; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Male; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Adolescent; Adult; Aged; Biliary Tract Diseases; Clinical Trials as Topic; Endocarditis, Bacterial; Female; Humans; Male; Middle Aged; Pneumonia; Pyelonephritis; Tetracycline

Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Resistance, Microbial; Erythromycin; Female; Humans; Male; Middle Aged; Pneumonia; Pyelonephritis; Tetracycline

Topics: Adolescent; Ampicillin; Child; Child, Preschool; Female; Humans; Indians, North American; Infant; Inuit; Male; Penicillin V; Pneumonia; Pneumonia, Viral; Tetracycline

Topics: Adult; Antibody Formation; Bacterial Vaccines; Clinical Trials as Topic; Erythromycin; Evaluation Studies as Topic; Humans; Male; Mycoplasma; Placebos; Pneumonia; Respiratory Tract Diseases; Tetracycline

Inhalation of dust containing silica particles is associated with severe pulmonary inflammation and lung injury leading to chronic silicosis including fibrotic remodeling of the lung. Silicosis represents a major global health problem causing more than 45.000 deaths per year. The inflammasome-caspase-1 pathway contributes to the development of silica-induced inflammation and fibrosis via IL-1β and IL-18 production. Recent studies indicate that tetracycline can be used to treat inflammatory diseases mediated by IL-1β and IL-18. Therefore, we hypothesized that tetracycline reduces silica-induced lung injury and lung fibrosis resulting from chronic silicosis via limiting IL-1β and IL-18 driven inflammation.. To investigate whether tetracycline is a therapeutic option to block inflammasome-caspase-1 driven inflammation in silicosis, we incubated macrophages with silica alone or combined with tetracycline. The in vivo effect of tetracycline was determined after intratracheal administration of silica into the mouse lung.. Tetracycline selectively blocks IL-1β production and pyroptotic cell death via inhibition of caspase-1 in macrophages exposed to silica particles. Consistent, treatment of silica-instilled mice with tetracycline significantly reduced pulmonary caspase-1 activation as well as IL-1β and IL-18 production, thereby ameliorating pulmonary inflammation and lung injury. Furthermore, prolonged tetracycline administration in a model of chronic silicosis reduced lung damage and fibrotic remodeling.. These findings suggest that tetracycline inhibits caspase-1-dependent production of IL-1β in response to silica in vitro and in vivo. The results were consistent with tetracycline reducing silica-induced pulmonary inflammation and chronic silicosis in terms of lung injury and fibrosis. Thus, tetracycline could be effective in the treatment of patients with silicosis as well as other diseases involving silicotic inflammation.

Topics: Animals; Caspase 1; Caspase Inhibitors; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Pneumonia; Protein Synthesis Inhibitors; Pulmonary Fibrosis; Silicon Dioxide; Tetracycline

Mycoplasma pneumoniae is a leading causative pathogen of pneumonia among pediatric patients, and its accurate diagnosis may aid in the selection of appropriate antimicrobial agents. We established a rapid reporting system of a polymerase chain reaction (PCR) examination for M. pneumoniae that enables physicians to obtain test results approximately 90 minutes after ordering the test. In this study, we evaluated the impact of this system on antimicrobial prescriptions for pediatric pneumonia patients after its implementation from May 2016 to April 2017. In total, we identified 375 pediatric pneumonia patients, and the results of the rapid PCR examinations for Mycoplasma pneumoniae were reported immediately in 90.7% of patients (340/375), with physicians able to use these results to decide on patients' management before the prescription of antimicrobial agents. Of the 375 pediatric pneumoniae patients, M. pneumoniae was detected in 223 (59.5%). Among the 223 M. pneumoniae-positive pneumonia cases, antimicrobial agents for atypical pathogens (macrolides, tetracyclines or quinolones) were prescribed in 97.3% (217/223) at the initial evaluation, and their prescription rates increased to 99.1% (221/223) during management. In contrast, antimicrobial agents for atypical pathogens were prescribed only in 10.5% of 152 M. pneumoniae-negative pneumonia cases at the initial evaluations, and only 1 additional case was prescribed clarithromycin for persistent symptoms during management. In conclusion, we show that molecular technology could be applicable in the field of point-of-care testing in infectious disease, and its implementation will ensure the correct antimicrobial prescription for pediatric pneumonia patients.

Topics: Adolescent; Anti-Bacterial Agents; Child; Drug Prescriptions; Female; Humans; Macrolides; Male; Mycoplasma pneumoniae; Pathology, Molecular; Pneumonia; Point-of-Care Systems; Quinolones; Tetracycline; Time Factors

To assess the high-resolution computed tomography appearances of drug-associated organizing pneumonia (OP).. Nine patients with clinical and biopsy proven drug-associated OP were included in the study. High-resolution computed tomography exams were retrospectively reviewed by 2 observers for the presence, extent, and distribution of parenchymal abnormalities.. The commonest findings consisted of air space consolidation (n = 8) and ground-glass opacification (n = 7). The air space consolidation was bilateral and asymmetric in 7 patients, symmetric in 1 patient and in all cases involved mainly the peribronchial or subpleural regions or both. The ground-glass opacities were predominantly bilateral and asymmetric in 6 patients and unilateral in 1 patient. They had a patchy distribution in 4 patients, were diffuse in 2 patients, and subpleural in 1 patient.. Drug-associated OP most commonly presents with bilateral, asymmetrical air space consolidation in a predominantly peribronchial and subpleural distribution.

Topics: Adult; Aged; Aged, 80 and over; Female; Heterocyclic Compounds; Humans; Lung; Male; Middle Aged; Nitrogen Mustard Compounds; Observer Variation; Pneumonia; Retrospective Studies; Tetracycline; Tomography, X-Ray Computed

Three patients with a chlamydial respiratory tract infection showed significant titre rises for the three chlamydial micro-immunofluorescence tests, performed with Chlamydia pneumoniae, C. psittaci and C. trachomatis. Such cross-reactions procure an inaccurate discrimination between the various Chlamydia species which remains speculative anyhow when only a positive serological profile against one chlamydial subspecies is performed. We consider that using the serologic assay as proof for past sexually transmitted C. trachomatis infection falls outside the limits of prudent interpretation of laboratory tests.

Topics: Aged; Animals; Anti-Bacterial Agents; Bird Diseases; Chlamydia; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Chlamydophila psittaci; Complement Fixation Tests; Erythromycin; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Parakeets; Pneumonia; Tetracycline

Chlamydia pneumoniae is emerging as a significant cause of respiratory disease, including pneumonia and bronchitis, in humans. In this recently completed study of infection due to C. pneumoniae in patients presenting with pneumonia to SUNY Health Science Center at Brooklyn, we identified two individuals for whom cultures were positive on multiple occasions over a 1-year period. To determine the frequency of persistent respiratory infection with C. pneumoniae, follow-up specimens were obtained from nine individuals with culture-documented C. pneumoniae infection. Five of these individuals had persistent infection: four had a flulike illness characterized by pharyngitis, and one had bronchitis with prominent bronchospasm. All five individuals appeared to have acute C. pneumoniae infection as determined by results of serologic tests (titers of IgM antibody for all individuals were greater than or equal to 1:16). For three patients, cultures remained positive for 11 months despite therapy with 10- to 21-day courses of tetracycline or doxycycline. These observations suggest that persistent infection with C. pneumoniae may follow acute infection and may persist for many months. Infection with C. pneumoniae may be very difficult to eradicate with use of currently available antibiotics even if there is a clinical response to therapy.

Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Chlamydia Infections; Chlamydophila pneumoniae; Chronic Disease; Doxycycline; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Pneumonia; Tetracycline

Patients with pneumonia not responding to treatment with betalactam drugs and patients where an "atypical" etiology is suspected from the beginning, are often given erythromycin to cover mycoplasma and legionella. Erythromycin has also been effective for Chlamydia pneumoniae. If, however, ornithosis is suspected the recommended drug has been tetracycline. Since we noted that several patients had a favourable course on erythromycin despite a final serological diagnosis of ornithosis, we retrospectively studied patients admitted with acute lower respiratory tract infection and a 4-fold titer rise to C. psittaci. We found 35 patients treated with a betalactam drug (n = 12), tetracycline (n = 2), or erythromycin (n = 5) alone, or with a betalactam, which because of non-responsiveness was followed by either tetracycline (n = 4) or erythromycin (n = 12). The data were analysed with survival analysis by a Cox' regression model. There was a significant (p less than 0.001) effect of treatment on the time to defervescence, mainly due to a difference between the erythromycin treated group and the betalactam treated group. We found erythromycin to be at least as effective as tetracycline for treating C. psittaci pneumonia. Since erythromycin has to be used to cover legionella in patients with severe pneumonia when an atypical etiology cannot be excluded, it is an important conclusion that this drug seems to cover C. psittaci as well.

Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Erythromycin; Fever; Humans; Lactams; Pneumonia; Psittacosis; Retrospective Studies; Tetracycline; Time Factors

Topics: Adult; Antigens, Bacterial; Chlamydia Infections; Chlamydophila psittaci; Complement Fixation Tests; Doxycycline; Erythromycin; Female; Humans; Minocycline; Pneumonia; Psittacosis; Tetracycline

A novel bacterium, Protomonas extorquens was isolated from sputum, pleural effusion and ascitis in four cases of pulmonary infection by buffered charcoal yeast extract agar (B-CYE) which was generally used for Legionella spp. Three cases were so-called immunocompromised hosts (2 malignant diseases, 1 renal failure), and they died from underlying diseases. Protomonas extorquens was newly named by Komagata in 1984, which was characterized by production of pink pigment, growth in methanol medium and positive production of oxidase and catalase. This organism is ordinarily isolated from soil and dead leaves. This is the first report for isolation of P. extorquens from clinical specimens in Japan and it seems to have a significant role in immunocompromised hosts.

Topics: Adult; Aged; Aged, 80 and over; Catalase; Culture Media; Drug Resistance, Microbial; Female; Gentamicins; Humans; Male; Methanol; Middle Aged; Oxidoreductases; Pigments, Biological; Pneumonia; Pseudomonas; Pseudomonas Infections; Tetracycline

Pneumonia is one of several clinical syndromes that results from inhalation of Coxiella burnetii. This microorganism, the etiologic agent of "Q" (query) fever, infects a wide range of animals and insects. Cattle, sheep, goats, and cats are the reservoirs whereby this agent is spread to humans. High concentrations of C burnetii are present in the placenta and at parturition, the organism is shed into the environment to be inhaled by humans. Following an incubation period that ranges from four to 30 days (mean 14 days), fever, headache, malaise, and cough ensue. The clinical presentation of pneumonia may range from a mild to a severe illness--the latter with the clinical picture of rapidly progressive pneumonia. There are no characteristic features of Q fever pneumonia but the severe headache and the epidemiological history should serve as clues. Treatment with tetracycline or rifampin for two weeks usually results in cure. Many cases of Q fever pneumonia remit without antibiotic therapy. The diagnosis is usually confirmed serologically using a complement fixation or microimmunofluorescence test.

Topics: Animals; Coxiella; Humans; Pneumonia; Q Fever; Radiography; Tetracycline; Zoonoses

Topics: Chlamydia; Chlamydia Infections; Humans; Pneumonia; Tetracycline

Topics: Acute Disease; Chlamydophila psittaci; Diagnosis, Differential; Humans; Male; Middle Aged; Pneumonia; Psittacosis; Radiography; Tetracycline

While the term "atypical pneumonia" has been in use for many years, it cannot in fact be defined. However, there is a persuasive reason to retain the clinical use of the term, and that is to provide a guide for the clinician in the choice of empirical antibiotic therapy for patients with acute pneumonia. Atypical pneumonia, then, is a descriptive term for a common clinical syndrome. Provided certain clinicoepidemiological groups are excluded, the most common infectious causes of this syndrome are Mycoplasma pneumoniae, Chlamydia psittaci, Coxiella burneti, and Legionella species, but it should be stressed that the syndrome may occasionally be produced by other infectious and non-infectious diseases. Conversely, the atypical pneumonia syndrome occupies only one part of the clinical spectrum of disease that is caused by these organisms. This becomes important when one is selecting antibiotic therapy for patients with other respiratory syndromes, especially those with life-threatening disease. The antimicrobial therapy of the three common causes of atypical pneumonia is discussed in detail.

Topics: Anti-Bacterial Agents; Erythromycin; Humans; Legionnaires' Disease; Pneumonia; Pneumonia, Mycoplasma; Psittacosis; Rifampin; Tetracycline

Two patients were admitted directly to our Intensive Care Unit in acute respiratory failure due to pneumonia with septicaemic shock, renal and hepatic impairment. Sputum and blood cultures failed to grow any organisms and despite broad spectrum antibiotic therapy for 7 days, neither patient improved. Diagnosis of the rare pneumonic form of psittacosis was made following a raised titre. After treatment with tetracyclines, both patients made a rapid recovery. Retrospective direct questioning revealed that they had close contact with psitacine birds.

Topics: Diagnosis, Differential; Humans; Male; Middle Aged; Multiple Organ Failure; Pneumonia; Psittacosis; Serologic Tests; Tetracycline

Topics: Humans; Legionellosis; Male; Middle Aged; Pneumonia; Spain; Tetracycline

The medical records of 94 patients with pneumonia who were not admitted to hospital were reviewed and compared with those of 25 patients admitted to hospital for treatment of pneumonia. In all, 93% of the outpatients in whom follow-up could be obtained did not require modification of treatment. This included patients older than 50 years of age without important underlying illness, patients with leukocyte counts of more than 14,000 per mu and patients with multilobular pneumonia. A properly obtained Gram-stained sputum specimen showing a predominant organism was the best method for determining the antimicrobial regimen. If sputum cannot be obtained for Gram's staining, erythromycin should be the drug of choice for patients younger than 40 years and ampicillin or erythromycin should be given to those patients older than 40 years who are managed outside of the hospital. Patients who are critically ill with tachypnea or hypoxia and those with severe underlying illness and pneumonia should be admitted to hospital.

Topics: Adult; Age Factors; Ambulatory Care; Ampicillin; Erythromycin; Female; Hospitalization; Humans; Leukocyte Count; Male; Middle Aged; Penicillins; Pneumonia; Risk; Tetracycline

Topics: Adult; Animals; California; Cats; Child; Female; Humans; Occupational Diseases; Plague; Pneumonia; Pregnancy; Tetracycline; Veterinary Medicine; Zoonoses

Topics: Adult; Animals; Cats; Child; Female; Humans; Occupational Diseases; Plague; Pneumonia; Pregnancy; Tetracycline; Veterinary Medicine; Zoonoses

Topics: Acute Kidney Injury; Adult; Drug Therapy, Combination; Female; Humans; Pneumonia; Sulfalene; Sulfanilamides; Tetracycline

Chlamydiae are obligate intracellular parasites, bacteria with a peculiar biology. They belong to the genus Chlamydia which includes two species: C. psittaci and C. trachomatis. A wide range of hosts, including birds, mammals and man can be infected by chlamydiae. The diseases chlamydiae can produce include psittacosis, lymphogranuloma venereum, trachoma, inclusion conjunctivitis, urethritis, cervicitis, pelvic inflammatory disease, and neonatal pneumonia. The diagnosis of chlamydial infection may be made by visualization of the organism in direct smears, isolation of the agent in cell culture, or by demonstrating a significant rise in antibody titer. Chlamydial infection may be treated with tetracycline, erythromycin, or sulfonamides.

Topics: Adult; Arthritis, Reactive; Child; Chlamydia Infections; Conjunctivitis, Inclusion; Epididymitis; Erythromycin; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lymphogranuloma Venereum; Male; Pelvic Inflammatory Disease; Pneumonia; Sexually Transmitted Diseases; Tetracycline; Trachoma; Urethritis; Uterine Cervicitis

Topics: Diagnosis, Differential; Erythromycin; Humans; Mycobacterium tuberculosis; Penicillins; Pneumonia; Tetracycline; Tuberculosis, Pulmonary

Topics: Ampicillin; Cephalothin; Gentamicins; Humans; Penicillins; Pneumonia; Tetracycline

An explosive, common-source outbreak of pneumonia caused by a previously unrecognized bacterium affected primarily persons attending an American Legion convention in Philadelphia in July, 1976. Twenty-nine of 182 cases were fatal. Spread of the bacterium appeared to be air borne. The source of the bacterium was not found, but epidemiologic analysis suggested that exposure may have occurred in the lobby of the headquarters hotel or in the area immediately surrounding the hotel. Person-to-person spread seemed not to have occurred. Many hotel employees appeared to be immune, suggesting that the agent may have been present in the vicinity, perhaps intermittently, for two or more years.

Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibodies, Bacterial; Bacteria; Child; Child, Preschool; Epidemiologic Methods; Erythromycin; Female; Fluorescent Antibody Technique; Humans; Legionnaires' Disease; Male; Middle Aged; Pennsylvania; Pneumonia; Risk; Tetracycline

Topics: Adolescent; Adult; Child; Disease Outbreaks; England; Erythromycin; Female; Humans; Male; Mycoplasma Infections; Oxytetracycline; Pneumonia; Pregnancy; Pregnancy Complications, Infectious; Recurrence; Tetracycline

During the winter months 1974/75 we were able to observe a number of unusual respiratory tract infections particularly in children over 6 years of age which appeared as pneumonias. Characteristic clinical findings included a dry, hacky cough, refractive to the usual antitussives, starting 1--2 weeks prior to admission, fever up to 104, malaise, headache, anorexia, shortness of breath and cyanosis. Several Pts were treated prior to admission with a number of antibiotics and failed to respond. Laboratory findings showed a peripheral polymorphonuclear leucocytosis with toxic granulations of neutrophiles. A sedimentation rate above 40 in the first hour occurred in most Pts. X Ray of the lung revealed a characteristic mottled appearance with patchy infiltrations, atelectasis and nodular densities. Frequently a shift of the mediastinum towards the infiltrate was seen. One of the hallmarks on physical examination was the discrepancy between the severity of the clinical illness and the paucity of physical findings. Decreased breath sounds over affected lung areas were often the only findings on auscultation; find rales, rhonchi or dullness on percussion were less often heard. The combination of a typical history, physical examination, laboratory tests and X Ray findings enabled us to make a presumptive clinical diagnosis of Mycoplasma pneumonia before serologic test results were available and to start with the appropriate antibiotic (Erythromycin, Tetracycline) early in the course of the disease. Complement fixation tests with a titer of 1 : 20 and a fourfold rise over the next two weeks or an initial titer of 1 : 80 and above were considered significant for acute disease.

Topics: Adolescent; Child; Child, Preschool; Erythromycin; Female; Humans; Male; Mycoplasma Infections; Otitis Media; Pneumonia; Rhinitis; Serologic Tests; Sinusitis; Tetracycline; Tonsillitis

Fifty patients who had pneumonia, lung abscess, or empyema, and whose specimens had a fetid odor, were presumed to be suffering from anerobic lung infection and were treated with clindamycin either orally (33 patients) or parenterally (17). Forty-six patients showed marked improvement or recovered; two also underwent lung resection, and thoracotomy was performed in 10. There were three outright treatment failures, and superinfection occurred in one patient. A review of the literature suggests that clindamycin and penicillin (in substantial dosage) are equally effective in treatment of anaerobic lung infection. Transtracheal aspiration is not deemed necessary if the patient is expectorating fetid sputum.

Topics: Adolescent; Adult; Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Chloramphenicol; Clindamycin; Diagnosis, Differential; Drug Evaluation; Empyema; Female; Humans; Lung Abscess; Male; Middle Aged; Penicillins; Pneumonia; Suction; Tetracycline

Topics: Humans; Meningitis; Mycoplasma Infections; Myelitis; Pneumonia; Tetracycline

Topics: Acute Disease; Erythromycin; Humans; Methacycline; Penicillins; Pneumonia; Streptomycin; Tetracycline

Topics: Adolescent; Adult; Female; Humans; Male; Mycoplasma Infections; Penicillins; Pneumonia; Tetracycline

Between August 1974 and October 1975 78 patients with mycoplasma-pneumonia-infection were admitted to the 3 pediatric clinics of Hannover. Their clinical and radiological findings were studied. 20 patients with serological diagnosis of additional viral infection were not included in this study. The clinical diagnosis was confirmed by complement fixation test. The commonest symptoms were fever, coughing and abnormal auscultatory findings over the lungs. Chest roentgenograms showed three different patterns of infiltration: 1. Disseminated, non homogenous bronchial lines and mottled shadows often with swollen hilar lymphnodes in 46% of all patients.--2. Homogenous, extensive, opaque infiltrates in 29% of all patients.--3. Perivascular and peribronchial infiltrates at the hilus with or without swollen lymphnodes in 21% of all patients.--This means that in half of the patients abnormal signs in chestroentgenogram (type 2 and 3) were present, which formerly were described as "atypical pneumonia."--4. There were no radiological symptoms in 4% of the patients.--Those who were treated with tetracyclin or erythromycin became afebrile within 1--3 days, in those who didn't get antibiotics at all or were treated with other antibiotics fever lasted longer.

Topics: Adolescent; Auscultation; Child; Child, Preschool; Complement Fixation Tests; Cough; Erythromycin; Female; Humans; Infant; Male; Mycoplasma Infections; Pneumonia; Radiography; Tetracycline

Topics: Antibodies, Bacterial; Complement Fixation Tests; Diagnosis, Differential; Erythromycin; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Tetracycline

A case of community-acquired pneumonia with Acinetobacter calcoacetium var. anitratus (Herellea vaginicola) is presented. Initial leukopenia and spare leukocytes in the sputum, followed by prolonged leukocytosis and fever, were unusual features of this case. The clinical significance and current antimicrobial drug therapy of acinetobacter infections are discussed.

Topics: Acinetobacter; Carbenicillin; Gentamicins; Humans; Male; Middle Aged; Pneumonia; Sepsis; Sputum; Tetracycline

Topics: Chloramphenicol; Doxycycline; Erythromycin; Humans; Leg; Lincomycin; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Penicillin Resistance; Penicillins; Pneumonia; Sepsis; Streptococcus pneumoniae; Tetracycline; Thrombophlebitis

Three cases of pneumonia caused by Neisseria meningitidis group Y are reported. From the results of these cases, the following conclusions were made. N. meningitidis probably can cause serious infection without preceding blood stream invasion. Primary meningococcal pneumonia is not rare; it has no distinctive clinical presentation; and it may not be recognized by routine expectorated sputum cultures. In addition, it may be associated with recent influenzal and adenoviral infections. Lastly, meningococci of the serogroup Y are capable of causing serious disease. Antimicrobial susceptibility studies showed that all three group Y isolates were sensitive to sulfadiazine and rifampin as well as to penicillin, ampicillin, erythromycin, and chloramphenicol.

Topics: Adenoviridae Infections; Adolescent; Adult; Female; Humans; Influenza, Human; Male; Meningococcal Infections; Microbial Sensitivity Tests; Neisseria meningitidis; Penicillin G Procaine; Penicillin Resistance; Pneumonia; Radiography; Tetracycline

A 31-year-old, previously healthy woman contracted Mycoplasma pneumoniae infection, proved by isolation and serologic titer rise. She was inadequately treated, and before complete recovery, she became ill with Haemophilus influenzae pneumonia and bacteremia.

Topics: Adult; Ampicillin; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Mycoplasma Infections; Penicillin G; Penicillin V; Pneumonia; Sepsis; Tetracycline

Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Arthritis, Infectious; Cattle; Cattle Diseases; Cystitis; Diarrhea; Escherichia coli Infections; Female; Foot Diseases; Fusobacterium Infections; Liver Abscess; Mastitis, Bovine; Meningitis; Osteomyelitis; Pasteurella Infections; Pneumonia; Respiratory Tract Infections; Salmonella Infections, Animal; Sheep; Sheep Diseases; Streptococcal Infections; Sulfonamides; Tetracycline; Uterine Diseases

Topics: Amputation, Surgical; Fingers; Gangrene; Humans; Injections, Intramuscular; Male; Malpractice; Ontario; Penicillin G Benzathine; Pneumonia; Tetracycline; Thumb

Topics: Acute Disease; Aminophylline; Anti-Bacterial Agents; Blood Coagulation; Body Temperature; Chronic Disease; Erythromycin; Furosemide; Heparin; Humans; Nikethamide; Nystatin; Oleandomycin; Penicillins; Peptide Hydrolases; Physical Therapy Modalities; Plasma Substitutes; Pneumonia; Pneumonia, Staphylococcal; Streptomycin; Strophanthins; Sulfadimethoxine; Sulfanilamides; Tetracycline; Vitamins

Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Resistance, Microbial; Drug Therapy, Combination; Endocarditis, Bacterial; Kanamycin; Microbial Sensitivity Tests; Pneumonia; Streptomycin; Tetracycline; Time Factors; Wounds and Injuries

The effect of intramuscular chimotripsin on the levels of methicillin and tetracycline administered respectively intramuscularly and orally was studied in patients with chronic pneumonia and in experimental rats. It was found that the dose of chimotripsin providing higher methicillin blood levels was many times lower than the enzyme doses providing analogous indices for the blood serum and organs of the rats. When the patients were treated with tetracycline and chimotripsin, increased blood levels of the antibiotic were observed. Administration of chimotripsin to the rats had no effect on tetracycline pharmacokinetics in the animals.

Topics: Animals; Anti-Bacterial Agents; Biological Availability; Chronic Disease; Chymotrypsin; Drug Interactions; Humans; Kinetics; Methicillin; Pneumonia; Rats; Tetracycline; Time Factors

Topics: Adenoviridae; Bacteria; Bacterial Infections; Cephalothin; Cytomegalovirus; Gentamicins; Haemophilus influenzae; Herpesvirus 3, Human; Humans; Klebsiella pneumoniae; Measles virus; Mycoplasma; Mycoplasma Infections; Orthomyxoviridae; Penicillins; Pneumonia; Pneumonia, Viral; Respiratory Syncytial Viruses; Respirovirus; Sputum; Staining and Labeling; Staphylococcus; Streptococcus pneumoniae; Tetracycline

Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteriological Techniques; Erythromycin; Female; Humans; Male; Middle Aged; Penicillins; Pneumococcal Infections; Pneumonia; Sepsis; Streptococcus pneumoniae; Tetracycline; United States

Topics: Anti-Bacterial Agents; Australia; Carrier State; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Pneumonia; Serotyping; Streptococcus pneumoniae; Tetracycline

Topics: Animals; Bovine Virus Diarrhea-Mucosal Disease; Cattle; Cattle Diseases; Clostridium Infections; Haemophilus Infections; Immunization; Infectious Bovine Rhinotracheitis; Paramyxoviridae Infections; Pasteurella Infections; Penicillins; Pneumonia; Respiratory Tract Infections; Stress, Physiological; Tetracycline

Topics: Adolescent; Child; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Tetracycline; Urinary Tract Infections

Topics: Acute Disease; Adult; Aminophylline; Anti-Infective Agents; Body Temperature; Camphor; Ephedrine; Erythromycin; Female; Humans; Male; Middle Aged; Nikethamide; Oleandomycin; Penicillins; Pneumonia; Sputum; Streptomycin; Sulfanilamides; Tetracycline

Topics: Aged; Ampicillin; Bone Marrow; Bone Marrow Cells; Carbamates; Cephaloridine; Cyclophosphamide; Cytarabine; Daunorubicin; Environmental Exposure; Humans; Imines; Insecticides; Leukemia, Erythroblastic, Acute; Lysosomes; Macrophages; Male; Microscopy, Electron; Mitochondria; Pneumonia; Prednisone; Sulfides; Tetracycline; Thioguanine; Vincristine

Topics: Adolescent; Adult; Aged; Agglutination Tests; Agglutinins; Antibodies, Bacterial; Autoantibodies; Cold Temperature; Complement Fixation Tests; Erythromycin; Female; Humans; Immunologic Techniques; Male; Mercaptoethanol; Middle Aged; Mycoplasma; Mycoplasma Infections; Pneumonia; Prospective Studies; Tetracycline; Time Factors

Topics: Acute Kidney Injury; Adult; Blood Coagulation Tests; Bronchopneumonia; Cytoplasm; Diagnosis, Differential; Disseminated Intravascular Coagulation; Female; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Necrosis; Pneumonia; Pregnancy; Respiratory Insufficiency; Seizures; Tetracycline; Time Factors; Twins; Uric Acid

Topics: Androgen Antagonists; Antibiotics, Antineoplastic; Bleomycin; Coumarins; Cyproterone; Endocarditis; Humans; Male; Neoplasms; Paraphilic Disorders; Pneumonia; Pregnadienes; Structure-Activity Relationship; Tetracycline; Urinary Tract Infections; Vitiligo

Topics: Anti-Bacterial Agents; Bacteria; Candidiasis; Cross Infection; Enterobacter; Female; Haemophilus influenzae; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Mutation; Mycoplasma Infections; Oxytetracycline; Penicillin Resistance; Penicillins; Pneumonia; Staphylococcal Infections; Staphylococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Streptomycin; Tetracycline

Topics: Carrier State; Cross Infection; Demeclocycline; Doxycycline; Drug Resistance, Microbial; Humans; Lincomycin; Microbial Sensitivity Tests; Minocycline; Pneumococcal Infections; Pneumonia; Streptococcus pneumoniae; Tetracycline

Topics: Child; Chronic Disease; Health Resorts; Humans; Penicillin G Benzathine; Physical Therapy Modalities; Pneumonia; Russia; Tetracycline

The effects of oral chemotherapy and stay in hospital on the antibiotic resistance patterns of faecal coliform flora were studied. The coliform flora of 64% of 25 patients who were not receiving antibiotics was sensitive to all drugs tested. Hospitalization alone did not affect this proportion. The administration of tetracycline or ampicillin to patients, whether at home or in hospital, significantly increased the percentage of resistant bowel coliforms. Tetracycline showed a significantly greater effect than ampicillin. There was no significant increase in the percentage of patients with resistant flora after treatment with amoxycillin.

Topics: Amines; Ampicillin; Bacteria; Bronchitis; Chloramphenicol; Feces; Hospitalization; Humans; Intestines; Kanamycin; Penicillin Resistance; Penicillins; Pneumonia; Sulfonamides; Tetracycline

Topics: Adult; Aged; Ampicillin; Bacteroides; Bacteroides Infections; Cephalothin; Chloramphenicol; Drug Evaluation; Empyema; Erythromycin; Female; Gentamicins; Humans; Kanamycin; Lincomycin; Male; Microbial Sensitivity Tests; Penicillin G; Peptococcus; Peptostreptococcus; Pneumonia; Sepsis; Tetracycline

Topics: Bacteriological Techniques; Culture Media; Drug Resistance, Microbial; Erythromycin; Fermentation; Humans; Hungary; Mycoplasma; Mycoplasma Infections; Oleandomycin; Pneumonia; Sputum; Tetracycline

Topics: Anti-Infective Agents; Asthma; Bronchiectasis; Bronchitis; Bronchopneumonia; Chloramphenicol; Drug Combinations; Enteritis; Folic Acid Antagonists; Humans; Intestinal Diseases; Lung Diseases; Microbial Sensitivity Tests; Pneumonia; Pyrimidines; Respiratory Tract Infections; Sulfamethoxazole; Tetracycline; Trimethoprim

Topics: Adolescent; Adult; Child; Diagnosis, Differential; Erythromycin; Humans; Immunologic Deficiency Syndromes; Male; Mycoplasma; Mycoplasma Infections; Pharynx; Pneumonia; Radiography; Tetracycline

Topics: Aged; Ampicillin; Cross Infection; Female; Humans; Klebsiella; Klebsiella Infections; Male; Pneumonia; Respiratory Tract Infections; Sputum; Tetracycline

Topics: Administration, Oral; Adult; Bronchiectasis; Bronchitis; Chloramphenicol; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Optic Neuritis; Pneumonia; Respiratory Tract Infections; Retrospective Studies; Tetracycline

Topics: Aged; Alkaline Phosphatase; Anemia; Blood Transfusion; Bone Marrow; Busulfan; Cytarabine; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Leukocytes; Male; Middle Aged; Pneumonia; Purpura; Radiography; Sepsis; Splenomegaly; Staphylococcal Infections; Tetracycline; Thioguanine

Topics: Administration, Oral; Bronchitis; Child; Child, Preschool; Dosage Forms; Female; Humans; Impetigo; Infant; Lymphadenitis; Male; Microbial Sensitivity Tests; Pneumonia; Respiratory Tract Infections; Staphylococcus; Tetracycline; Tonsillitis; Whooping Cough

Topics: Acute Disease; Acute Kidney Injury; Adult; Chronic Disease; Creatinine; Diet Therapy; Dietary Proteins; Female; Fever; Gastrointestinal Hemorrhage; Humans; Kidney Failure, Chronic; Lupus Erythematosus, Systemic; Male; Middle Aged; Peritoneal Dialysis; Pneumonia; Prednisone; Tetracycline; Urea; Uremia

Topics: Arthritis, Rheumatoid; Complement Fixation Tests; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Sputum; Tetracycline; Urethritis

Topics: Adult; Aged; Bronchitis; Cholangitis; Chronic Disease; Drug Combinations; Female; Hepatitis; Humans; Male; Middle Aged; Oleandomycin; Pneumonia; Pyelonephritis; Tetracycline

Topics: Adolescent; Adult; Aged; Chlamydia; Female; Humans; Male; Middle Aged; Pneumonia; Psittacosis; Tetracycline

Topics: Arthritis; Erythromycin; Humans; Mycoplasma Infections; Pneumonia; Serologic Tests; Switzerland; Tetracycline; Urethritis

Topics: Aged; Blood Sedimentation; Body Temperature; Chloramphenicol; Erythromycin; Female; Humans; Middle Aged; Penicillins; Pneumonia; Prednisolone; Streptomycin; Sulfonamides; Tetracycline

Topics: Adult; Encephalitis; Humans; Male; Mycoplasma; Mycoplasma Infections; Pneumonia; Prognosis; Radiography; Tetracycline

Topics: Adolescent; Adult; Age Factors; Aged; Antibodies; Antibodies, Antinuclear; Blood Sedimentation; Child; Cold Temperature; Complement Fixation Tests; Coombs Test; Disease Outbreaks; Finland; Fluorescent Antibody Technique; Humans; Mycoplasma; Mycoplasma Infections; Otitis; Pharynx; Pneumonia; Precipitins; Seasons; Stevens-Johnson Syndrome; Tetracycline; Tonsillitis; Urticaria

Topics: Abdomen; Anti-Bacterial Agents; Appendicitis; Chloramphenicol; Chronic Disease; Erythromycin; Erythromycin Ethylsuccinate; Escherichia coli; Exudates and Transudates; Herniorrhaphy; Humans; Neomycin; Penicillin Resistance; Penicillins; Pneumonia; Postoperative Complications; Staphylococcal Infections; Staphylococcus; Streptomycin; Surgical Wound Infection; Tetracycline

Topics: Adolescent; Adult; Chloramphenicol; Erythromycin; Female; Humans; Male; Middle Aged; Mycoplasma Infections; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Aged; Cephalosporins; Chloramphenicol; Digitalis Glycosides; Erythromycin; Female; Humans; Infections; Oxygen Inhalation Therapy; Penicillins; Pneumococcal Infections; Pneumonia; Respiratory Insufficiency; Streptococcal Infections; Tetracycline

Topics: Adult; Antibodies; Antibody Formation; Chronic Disease; Erythromycin; Female; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Radiography, Thoracic; Tetracycline; Time Factors

Topics: Adult; Anemia, Hemolytic; Female; Humans; Mycoplasma Infections; Myocarditis; Pleural Effusion; Pneumonia; Tetracycline

Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Bronchiectasis; Bronchitis; Cephaloridine; Chloramphenicol; Chronic Disease; Cloxacillin; Erythromycin; Humans; Lactose; Methicillin; Oxytetracycline; Penicillin G; Penicillin Resistance; Pneumonia; Pneumonia, Staphylococcal; Pneumonia, Viral; Streptomycin; Tetracycline

Topics: Aged; Ampicillin; Chronic Disease; Drug Synergism; Haemophilus influenzae; Humans; Lung Diseases, Obstructive; Male; Nystatin; Pneumonia; Sputum; Sulfonamides; Tetracycline; Trimethoprim

Topics: Alpha-Globulins; Diagnosis, Differential; Female; Fluorescence; Humans; Lung Neoplasms; Male; Methods; Pleural Effusion; Pneumonia; Sputum; Tetracycline

Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Bacteria; Chloramphenicol; Chlortetracycline; Depression, Chemical; Enterococcus faecalis; Erythromycin; Erythromycin Ethylsuccinate; Female; Furazolidone; Humans; Male; Middle Aged; Neomycin; Nitrofurantoin; Oleandomycin; Oxytetracycline; Penicillin G; Penicillin Resistance; Penicillins; Pneumonia; Polymyxins; Ristocetin; Staphylococcus; Streptococcus; Streptomycin; Tetracycline; Urine

Topics: Cholecystitis; Humans; Pancreatitis; Pneumonia; Tetracycline

Topics: Age Factors; Ampicillin; Asthma; Child; Female; Humans; Hypersensitivity; Male; Penicillins; Pneumonia; Radiography; Respiratory Hypersensitivity; Sex Factors; Sinusitis; Tetracycline

Topics: Abdomen; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bronchiectasis; Child; Cholecystitis; Female; Humans; Injections, Intravenous; Lung Abscess; Lung Diseases; Male; Middle Aged; Morpholines; Myocarditis; Oleandomycin; Osteomyelitis; Pancreatitis; Peritonitis; Pneumonia; Tetracycline; Thoracic Surgery; Thorax

Topics: Adult; Aged; California; Cephalothin; Child; Female; Genes; Genetics, Microbial; Hemadsorption Inhibition Tests; Hemagglutination Inhibition Tests; Hematocrit; Humans; Influenza, Human; Leukocyte Count; Male; Middle Aged; Orthomyxoviridae; Pneumonia; Pregnancy; Pregnancy Complications, Infectious; Radiography; Tetracycline; Virus Replication

Topics: Ampicillin; Anti-Bacterial Agents; Bronchitis; Cephalosporins; Humans; Penicillin G; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Adult; Aged; Bronchitis; Empyema; Female; Humans; Male; Middle Aged; Pleurisy; Pneumonia; Tetracycline; Urinary Tract Infections

Topics: Adolescent; Child; Child, Preschool; Erythromycin; Female; Follow-Up Studies; Humans; Male; Mycoplasma Infections; Pneumonia; Population Surveillance; Seasons; Tetracycline; Urban Population; Washington

Topics: Adult; Animals; Cat Diseases; Cats; Chlamydia; Chlamydia Infections; Conjunctiva; Conjunctivitis; Humans; Keratoconjunctivitis; Male; Pneumonia; Tetracycline; Zoonoses

Topics: Adult; Aged; Body Temperature; Female; Humans; Injections, Intramuscular; Leukocyte Count; Lung; Lung Abscess; Male; Middle Aged; Penicillin V; Pneumonia; Radiography; Respiratory Tract Infections; Tetracycline; Tonsillitis

Topics: Adult; Bronchiectasis; Bronchitis; Endocarditis; Female; Gallbladder Diseases; Humans; Injections, Intramuscular; Liver; Liver Function Tests; Lung Abscess; Male; Middle Aged; Penicillin Resistance; Penicillin V; Pneumonia; Pyelonephritis; Respiratory Tract Infections; Sepsis; Tetracycline; Tonsillitis

Topics: Abscess; Adolescent; Bronchitis; Child; Child, Preschool; Female; Humans; Infant; Male; Measles; Penicillin V; Pharyngeal Diseases; Pneumonia; Respiratory Tract Infections; Stomatitis; Tetracycline

Topics: Adolescent; Adult; Bronchitis; Cholecystitis; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Penicillin Resistance; Penicillin V; Pneumonia; Pyelonephritis; Respiratory Tract Infections; Staphylococcus; Tetracycline; Tonsillitis

Topics: Adult; Cystitis; Female; Gallbladder Diseases; Humans; Injections, Intramuscular; Lung Abscess; Male; Middle Aged; Penicillin Resistance; Penicillin V; Peritonsillar Abscess; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Adult; Aged; Bronchiectasis; Female; Gallbladder Diseases; Humans; Injections, Intramuscular; Leukocyte Count; Lung Abscess; Male; Middle Aged; Penicillin Resistance; Penicillin V; Pneumonia; Pyelonephritis; Respiratory Tract Infections; Tetracycline

Topics: Adolescent; Bronchitis; Child; Child, Preschool; Coagulase; Female; Humans; Male; Mycoplasma Infections; Penicillin V; Pharyngitis; Pneumonia; Pyoderma; Staphylococcus; Suppuration; Tetracycline; Tonsillitis

Topics: Humans; Mycoplasma; Mycoplasma Infections; Penicillin Resistance; Penicillins; Pneumonia; Radiography; Tetracycline

Topics: Adolescent; Age Factors; Child; Drug Resistance, Microbial; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Mycoplasma Infections; Pneumonia; Staphylococcus; Tetracycline

Topics: Adult; Aged; Anti-Bacterial Agents; Chloramphenicol; Dysentery, Bacillary; Enterocolitis, Pseudomembranous; Erythromycin; Humans; Intestines; Male; Middle Aged; Nalidixic Acid; Nystatin; Penicillins; Pneumonia; Proteus Infections; Rheumatic Heart Disease; Staphylococcal Infections; Streptomycin; Tetracycline

Topics: Acute Disease; Adult; Chronic Disease; Female; Humans; Male; Middle Aged; Pneumonia; Tetracycline

Topics: Adult; Animals; Cat Diseases; Cats; Chlamydia; Chlamydia Infections; Conjunctiva; Conjunctivitis; Drug Resistance, Microbial; Humans; Male; Pneumonia; Tetracycline; Zoonoses

Topics: Adult; Cephalothin; Humans; Male; Mycoplasma; Mycoplasma Infections; Pneumonia; Polyradiculopathy; Respiratory Insufficiency; Tetracycline

Topics: Adolescent; Adult; Aged; Asthma; Bronchitis; Child; Child, Preschool; Chronic Disease; Female; Humans; Male; Middle Aged; Pneumonia; Tablets; Tetracycline

Topics: Bronchography; Caffeine; Child, Preschool; Female; Humans; Infant; Leukocytosis; Lymphocytosis; Male; Oxygen Inhalation Therapy; Oxytetracycline; Penicillins; Petroleum; Pneumonia; Promethazine; Pulmonary Emphysema; Tachycardia; Tetracycline

Topics: Anti-Bacterial Agents; Bronchitis; Child; Chloramphenicol; Diphtheria; Erythromycin; Humans; Infection Control; Infections; Influenza, Human; Measles; Penicillins; Pneumonia; Scarlet Fever; Sulfonamides; Tetracycline; Tonsillitis; Whooping Cough

Topics: Acute Disease; Anti-Bacterial Agents; Bronchiolitis, Viral; Bronchitis; Chronic Disease; Cross Infection; Humans; Laryngitis; Penicillin Resistance; Penicillins; Pharyngitis; Pneumonia; Respiratory Tract Infections; Tetracycline; Tracheitis

Topics: Bronchitis; Child; Dental Enamel; Erythromycin; Humans; Iatrogenic Disease; Otitis Media; Penicillins; Pneumonia; Tetracycline

Topics: Adult; Aged; Agglutination Tests; Animals; Antibodies; Coxiella; Disease Reservoirs; Disease Vectors; Dust; Female; Humans; Male; Pneumonia; Q Fever; Tetracycline; Texas

Topics: Acute Disease; Anti-Bacterial Agents; Bronchitis; Child; Child, Preschool; Chloramphenicol; Chronic Disease; Communicable Diseases; Diarrhea, Infantile; Enteritis; Humans; Hypersensitivity; Meningitis; Pneumonia; Pyelonephritis; Sepsis; Skin Diseases; Staphylococcal Infections; Tetracycline; Tooth Diseases; Tooth, Deciduous; Vomiting; Whooping Cough

Topics: Adolescent; Adult; Aged; Bronchitis; Female; Humans; Male; Middle Aged; Pneumonia; Respiratory Therapy; Tetracycline

Topics: Child; Child, Preschool; Cholecystitis; Humans; Infant; Pneumonia; Rolitetracycline; Staphylococcal Infections; Tetracycline

Topics: Adult; Child; Child, Preschool; Female; Humans; Male; Mycoplasma Infections; Penicillins; Pneumonia; Tetracycline

Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Bronchitis; Female; Humans; Male; Middle Aged; Pneumonia; Tetracycline; Urinary Tract Infections

Topics: Adult; Culture Media; Drug Resistance, Microbial; Erythromycin; Humans; Male; Mycoplasma; Pneumonia; Sputum; Tetracycline

Topics: Ecology; Erythromycin; Humans; Military Personnel; Mycoplasma; Pneumonia; Serologic Tests; Tetracycline; Vaccination

Topics: Adult; Aged; Chloramphenicol; Chlortetracycline; Complement Fixation Tests; Diagnosis, Differential; Disease Reservoirs; Female; Humans; Male; Middle Aged; Penicillin G; Pneumonia; Procaine; Psittacosis; Radiography, Thoracic; Tetracycline

Topics: Erythromycin; Humans; Mycoplasma; Pneumonia; Tetracycline

Topics: Adolescent; Adult; Anti-Bacterial Agents; Chloramphenicol; Female; Humans; Hydrocortisone; Leukocyte Count; Male; Meningoencephalitis; Methicillin; Mycoplasma; Penicillin G; Pneumonia; Serologic Tests; Tetracycline

Topics: Asthma; Blood Protein Disorders; Bronchiectasis; Bronchitis; Child; Child, Preschool; Dermatitis, Seborrheic; Eczema; Female; gamma-Globulins; Humans; Infant; Infant, Newborn; Malabsorption Syndromes; Male; Methacycline; Otitis Media; Pneumonia; Pyelonephritis; Respiratory Tract Infections; Tetracycline; Tonsillectomy

Topics: Adrenocorticotropic Hormone; Aged; Anemia, Hemolytic; Antibiosis; Dexamethasone; Female; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Serum Albumin; Tetracycline; Thromboembolism

Topics: Anti-Bacterial Agents; Bacteria; Chloramphenicol; Chlortetracycline; Erythromycin; Erythromycin Ethylsuccinate; Escherichia coli; Klebsiella; Neomycin; Oleandomycin; Oxytetracycline; Penicillin Resistance; Penicillins; Pneumonia; Proteus; Pseudomonas; Saccharomyces; Sputum; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Streptomycin; Tetracycline

Topics: Bronchitis; Cephalothin; Child; Child, Preschool; Chloramphenicol; Empyema; Epiglottis; Erythromycin; Escherichia coli; Haemophilus Infections; Haemophilus influenzae; Histoplasma; Humans; Infant; Klebsiella; Laryngeal Diseases; Methicillin; Mycobacterium tuberculosis; Otitis Media; Penicillins; Pneumonia; Pseudomonas; Respiratory Tract Infections; Sinusitis; Staphylococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Streptomycin; Tetracycline

Topics: Adult; Ascorbic Acid; Chronic Disease; Escherichia coli Infections; Female; Humans; Infections; Lung Diseases; Male; Middle Aged; Osteomyelitis; Peritonitis; Pleural Diseases; Pneumonia; Staphylococcal Infections; Streptococcal Infections; Suppuration; Surgical Wound Infection; Tetracycline; Thiamine

Topics: Adult; Animals; Bone and Bones; Bone Neoplasms; Chondrosarcoma; Fluorescence; Humans; Infection Control; L Forms; Male; Mice; Pancreatitis; Pericarditis; Pneumonia; Postoperative Complications; Rabbits; Tetracycline

Topics: Adult; Agglutination; Child; Child, Preschool; Complement Fixation Tests; Female; Fluorescent Antibody Technique; Humans; Male; Mycobacterium; Mycobacterium Infections; Ohio; Pneumonia; Population Surveillance; Respiratory Tract Infections; Tetracycline

Topics: Anti-Bacterial Agents; Drug Synergism; Erythromycin; Humans; Infant; Neomycin; Oleandomycin; Otitis; Pneumonia; Sepsis; Staphylococcal Infections; Tetracycline

Topics: Child; Child, Preschool; Complement Fixation Tests; Diagnosis, Differential; Female; Humans; Mycoplasma; Mycoplasma Infections; Pneumonia; Radiography; Tetracycline

Topics: Acute Disease; Acute Kidney Injury; Adult; Enterocolitis, Pseudomembranous; Erythromycin; Humans; Isotonic Solutions; Male; Nephrosis; Pneumonia; Tetracycline; Ultrasonics

Topics: Adolescent; Adult; Child; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pneumonia; Tetracycline; USSR

Topics: Adult; Diagnosis, Differential; Humans; Kanamycin; Male; Melioidosis; Military Medicine; Pneumonia; Prognosis; Radiography; Tetracycline; Tuberculosis, Pulmonary; Vietnam

Topics: Child; Child, Preschool; Communicable Diseases; Humans; Infant; Infant, Newborn; Methacycline; Pneumonia; Stomatitis; Tetracycline; Tooth Discoloration

Topics: Catheterization; Child; Child, Preschool; Chloramphenicol; Empyema; Erythromycin; Humans; Infant; Infant, Newborn; Kanamycin; Mortality; Novobiocin; Penicillin Resistance; Penicillins; Pneumonia; Pneumothorax; Radiography, Thoracic; Staphylococcal Infections; Streptomycin; Tetracycline

Topics: Adolescent; Adult; Bronchiectasis; Female; Humans; India; Lung Abscess; Male; Methacycline; Middle Aged; Pneumonia; Tetracycline

Topics: Adult; Bronchitis; Humans; Male; Middle Aged; Mycoplasma; Pharyngitis; Pneumonia; Tetracycline

Topics: Aged; Drug Resistance, Microbial; Female; Humans; Pneumococcal Infections; Pneumonia; Tetracycline

Topics: Animals; Brucellosis, Bovine; Cattle; Humans; Male; Middle Aged; Pneumonia; Prednisone; Tetracycline

Topics: Adolescent; Adult; Carrier State; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Mycoplasma; Pneumonia; Tetracycline

Topics: Anti-Bacterial Agents; Humans; Lymphangitis; Oleandomycin; Osteomyelitis; Peritonitis; Pneumonia; Postoperative Complications; Staphylococcal Infections; Tetracycline; Wound Infection

Topics: Adolescent; Anti-Bacterial Agents; Blood Cells; Blood Sedimentation; Chloramphenicol; Clinical Laboratory Techniques; Diagnosis; Drug Therapy; Erythromycin; Geriatrics; Mortality; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Radiography, Thoracic; Spiramycin; Sputum; Tetracycline

Topics: Anti-Bacterial Agents; Black People; Diagnosis, Differential; Drug Therapy; Epidemiology; Humans; Penicillins; Pneumonia; Psittacosis; Radiography, Thoracic; South Africa; Tetracycline

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Drug Therapy; Oleandomycin; Pneumonia; Tetracycline

Topics: Aerosols; Child; Drug Therapy; Humans; Infant; Pneumonia; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Infections; Tetracycline; Water

Topics: Anti-Bacterial Agents; Humans; Oleandomycin; Pneumonia; Tetracycline

Topics: Anti-Bacterial Agents; Bronchitis; Common Cold; Culture Media; Glucocorticoids; Humans; Influenza Vaccines; Influenza, Human; Penicillins; Pneumonia; Respiratory Tract Infections; Sputum; Tetracycline

Topics: Drug Resistance; Drug Resistance, Microbial; Humans; Pneumococcal Infections; Pneumonia; Pneumonia, Pneumococcal; Tetracycline

Topics: Betainfluenzavirus; Child; Chloramphenicol; Croup; Diphenhydramine; Hemagglutination Inhibition Tests; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Immune Sera; Infant; Influenza B virus; Laryngitis; Orthomyxoviridae; Oxygen Inhalation Therapy; Pneumonia; Pneumonia, Viral; Radiography; Seasons; Tetracycline

Topics: Anti-Bacterial Agents; Candidiasis; Candidiasis, Oral; Deglutition Disorders; Diagnosis; Esophagitis; Humans; Nystatin; Pneumonia; Prednisolone; Radiography; Sulfonamides; Tetracycline

Topics: Anti-Bacterial Agents; Bronchitis; Chloramphenicol; Erythromycin; Haemophilus influenzae; Novobiocin; Penicillins; Pneumococcal Infections; Pneumonia; Scotland; Staphylococcal Infections; Statistics as Topic; Streptomycin; Tetracycline; Virus Diseases

Topics: Antitussive Agents; Bronchial Diseases; Bronchitis; Bronchopneumonia; Hemopneumothorax; Humans; Influenza, Human; Lung Diseases; Oxadiazoles; Pleurisy; Pneumonia; Pneumonia, Viral; Respiratory Tract Infections; Tetracycline

Topics: Anti-Bacterial Agents; Humans; Nystatin; Phosphates; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Abscess; Anti-Bacterial Agents; Bacitracin; Bronchial Fistula; Chloramphenicol; Empyema; Erythromycin; Humans; Kanamycin; Novobiocin; Penicillins; Pleural Effusion; Pneumonia; Pneumonia, Staphylococcal; Pneumothorax; Sepsis; Staphylococcal Infections; Tetracycline; Vancomycin

Topics: Birds; Child; Chlamydia; Chlamydophila psittaci; Complement Fixation Tests; Epidemiology; Fever; Humans; Influenza, Human; Lymphogranuloma Venereum; Penicillins; Pneumonia; Psittacosis; Scotland; Sulfonamides; Tetracycline

Topics: Bacteremia; Bacteriological Techniques; Chloramphenicol; Drug Therapy; Erythromycin; Immunization, Passive; Klebsiella; Leukocyte Count; New York; Penicillins; Pneumococcal Infections; Pneumonia; Pneumonia, Pneumococcal; Sepsis; Statistics as Topic; Streptococcal Infections; Streptomycin; Tetracycline

Topics: Abscess; Air Microbiology; Antisepsis; Bacteriological Techniques; Bacteriophage Typing; Burns; Chloramphenicol; Drug Resistance; Drug Resistance, Microbial; Empyema; Enteritis; Epidemiology; Osteomyelitis; Penicillins; Pneumonia; Postoperative Complications; Pressure Ulcer; Pyelonephritis; Sepsis; Staphylococcal Infections; Staphylococcus; Staphylococcus Phages; Tetracycline; Toxicology; Wound Infection

Topics: Adolescent; Animals; Anti-Bacterial Agents; Cellulitis; Child; Endocarditis; Erythromycin; Female; Furunculosis; Fusidic Acid; Geriatrics; Humans; Infant; Meningitis; Osteomyelitis; Penicillins; Pneumonia; Pregnancy; Puerperal Infection; Pyelonephritis; Staphylococcal Infections; Streptomycin; Sulfonamides; Tetracycline; Wound Infection

Topics: Aminosalicylic Acid; Aminosalicylic Acids; Child; Diagnosis, Differential; Humans; Isoniazid; Lipids; Paraffin; Penicillins; Pneumonia; Pneumonia, Lipid; Prednisolone; Radiography, Thoracic; Tetracycline; Toxicology; Tuberculosis; Tuberculosis, Pulmonary

Topics: Adolescent; Aerosols; Anti-Bacterial Agents; Candidiasis; Child; Chloramphenicol; Drug Therapy; Erythromycin; Follow-Up Studies; Humans; Infant; Kanamycin; Leukopenia; Methicillin; Neomycin; Novobiocin; Oxygen Inhalation Therapy; Penicillins; Pneumonia; Pneumonia, Staphylococcal; Radiography, Thoracic; Staphylococcal Infections; Tetracycline; Toxicology

Topics: Acidosis; Cesarean Section; Fatty Liver; Female; Hematemesis; Humans; Hypoproteinemia; Hypotension; Hysterectomy; Jaundice; Liver Diseases; Melena; Oxytetracycline; Pathology; Placenta Previa; Pneumonia; Postpartum Hemorrhage; Postpartum Period; Pregnancy; Pregnancy Complications; Tetracycline; Toxicology

Topics: Agar; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloramphenicol; Drug Resistance, Microbial; Erythrocytes; Erythromycin; Guinea Pigs; Hemolysin Proteins; Horses; Humans; In Vitro Techniques; Mycoplasma; Mycoplasma pneumoniae; Penicillin V; Penicillins; Pneumonia; Pneumonia, Viral; Research; Tetracycline

Topics: Amphotericin B; Candidiasis; Geriatrics; Humans; Lung Diseases, Fungal; Nystatin; Organic Chemicals; Pneumonia; Radiography, Thoracic; Tetracycline

Topics: Aerosols; Anti-Bacterial Agents; Humans; Lung Abscess; Oxygen Inhalation Therapy; Pneumonia; Pneumonia, Staphylococcal; Pregnancy; Respiration, Artificial; Staphylococcal Infections; Tetracycline

Topics: Adenoviridae; Adenoviridae Infections; Diagnosis; Drug Therapy; Enterovirus; Enterovirus B, Human; Epidemiology; Geriatrics; Mycoplasma; Orthomyxoviridae; Pneumonia; Pneumonia, Viral; Poxviridae; Respiratory Tract Infections; Rhinovirus; Tetracycline

Topics: Adolescent; Anti-Bacterial Agents; Antibody Formation; Drug Resistance; Drug Resistance, Microbial; Hemolysis; Humans; Kanamycin; Microbiology; Mycoplasma; Mycoplasma pneumoniae; Penicillins; Pneumonia; Pneumonia, Bacterial; Pneumonia, Viral; Sulfonamides; Tetracycline

Topics: Adolescent; Anemia, Hemolytic; Erythema Multiforme; Humans; Infections; Mycoplasma; Mycoplasma Infections; Pneumonia; Pneumonia, Mycoplasma; Pneumonia, Viral; Prednisone; Radiography, Thoracic; Tetracycline

Topics: Anti-Bacterial Agents; Biomedical Research; Bronchiectasis; Bronchitis; Bronchitis, Chronic; Drug Tolerance; Lymecycline; Pneumonia; Pneumonia, Pneumococcal; Sputum; Statistics as Topic; Tetracycline; Toxicology

Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Chloramphenicol; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Erythromycin; Incidence; Klebsiella; Penicillins; Pneumonia; Streptomycin; Tetracycline

Topics: Aerosols; Anti-Bacterial Agents; Bacitracin; Bacteriological Techniques; Bronchitis; Chloramphenicol; Diagnosis; Drug Therapy; Humans; Neomycin; Penicillins; Pharyngitis; Pneumonia; Respiratory Tract Infections; Streptomycin; Sulfonamides; Tetracycline; Tracheitis; Virus Diseases

Topics: Anti-Bacterial Agents; Drug Therapy; Erythromycin; Humans; Lung Diseases; Lung Diseases, Fungal; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Pneumonia, Rickettsial; Pneumonia, Viral; Streptomycin; Tetracycline; Tuberculosis

Topics: Air Conditioning; Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Escherichia coli; Haemophilus influenzae; Humans; Influenza, Human; Nose; Pharynx; Pneumonia; Pneumonia, Viral; Pseudomonas aeruginosa; Staphylococcus; Sterilization; Streptococcus pneumoniae; Tetracycline

Topics: Anti-Bacterial Agents; Erythromycin; Humans; Penicillins; Peptide Hydrolases; Pneumonia; Pneumonia, Pneumococcal; Tetracycline

Topics: Anti-Bacterial Agents; Child; Complement Fixation Tests; Diagnosis, Differential; Humans; Pneumonia; Protein Synthesis Inhibitors; Psittacosis; Tetracycline

Topics: Anti-Bacterial Agents; Bordetella pertussis; Bronchitis; Child; Erythromycin; Humans; Penicillins; Pertussis Vaccine; Pneumonia; Protein Synthesis Inhibitors; Tetracycline; Whooping Cough

Topics: Anti-Bacterial Agents; Child; Chlorpromazine; Erythromycin; gamma-Globulins; Infant; Infant, Newborn; Oxytetracycline; Penicillins; Pneumococcal Infections; Pneumonia; Pneumonia, Viral; Staphylococcal Infections; Streptomycin; Tetracycline

Topics: Animals; Anti-Bacterial Agents; Bronchitis; Bronchopneumonia; Endocarditis; Endocarditis, Bacterial; Furunculosis; Humans; Lung Abscess; Plants, Medicinal; Pneumonia; Pyelitis; Pyelocystitis; Sepsis; Tetracycline

Topics: Asthma; Bronchiectasis; Bronchitis; Humans; Novobiocin; Pneumonia; Respiratory Tract Infections; Tetracycline

Topics: Adenoviridae Infections; Anti-Bacterial Agents; Bronchopneumonia; Child; Cortisone; Erythromycin; Humans; Infant; Influenza, Human; Penicillins; Plasma Cells; Pneumonia; Pneumonia, Pneumocystis; Pneumonia, Rickettsial; Pneumonia, Viral; Psittacosis; Pulmonary Fibrosis; Q Fever; Streptomycin; Tetracycline

Topics: Anti-Bacterial Agents; Drug Resistance; Drug Resistance, Microbial; Escherichia coli Infections; Penicillins; Pneumonia; Postoperative Complications; Staphylococcal Infections; Streptomycin; Tetracycline

Topics: Anti-Bacterial Agents; Drug Therapy; Epidemiology; Erythromycin; Humans; Immunization, Passive; Influenza, Human; Penicillins; Pneumonia; Sulfathiazoles; Tetracycline; USSR

Topics: Anti-Bacterial Agents; Bacillus; Biomedical Research; Brucellosis; Chloramphenicol; Chlortetracycline; Communicable Diseases; Cycloserine; Diphtheria; Dysentery; Dysentery, Bacillary; Erythromycin; Escherichia coli Infections; Humans; Influenza, Human; Liver Extracts; Methicillin; Penicillins; Pneumonia; Research; Staphylococcal Infections; Streptomycin; Syphilis; Tetracycline; Trachoma; Tuberculosis; USSR

Topics: Anti-Bacterial Agents; Chloramphenicol; Humans; Klebsiella; Klebsiella Infections; Pneumonia; Streptomycin; Tetracycline

Topics: Anti-Bacterial Agents; Biomedical Research; Methylprednisolone; Pneumonia; Pneumonia, Pneumococcal; Prednisolone; Research Design; Tetracycline

Topics: Anti-Bacterial Agents; Bronchopneumonia; Kidney Diseases; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Sulfonamides; Tetracycline

Topics: Animals; Chlamydia; Chlamydophila psittaci; Chlortetracycline; Goats; Pneumonia; Psittacosis; Tetracycline; Virus Diseases; Viruses

Topics: Anti-Bacterial Agents; Bacillus; Humans; Pneumonia; Protein Synthesis Inhibitors; Streptomycin; Sulfanilamide; Sulfanilamides; Sulfonamides; Tetracycline

Over 50 per cent of all staphylococcic infections are hospital-acquired. In 92 per cent of hospital-acquired infection, the organism is resistant to penicillin, and in 74 per cent to tetracycline.Chloramphenicol, bacitracin, novobiocin and erythromycin are the drugs of choice for therapy. There was good correlation between clinical response and antibiotic therapy selected on the basis of results of organism sensitivity tests done by the agar diffusion technique.Cross-resistance among the tetracyclines averaged 94 per cent. Erythromycin and magnamycin showed similar pattern. Mortality in infants less than two months old was 7.8 per cent as compared with 1.1 per cent in older children. Death was related either to pneumonia or to septicemia in the ten fatalities recorded in this series.

Topics: Anti-Bacterial Agents; Bacitracin; Child; Chloramphenicol; Erythromycin; Humans; Infant; Micrococcus; Novobiocin; Penicillins; Pneumonia; Sepsis; Tetracycline; Tetracyclines

Topics: Anti-Bacterial Agents; Child; Humans; Infant; Pneumonia; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Fever; Hospitalization; Humans; Pneumonia; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Chlortetracycline; Erythromycin; Humans; Mycoplasma Infections; Oxytetracycline; Pneumonia; Pneumonia, Mycoplasma; Tetracycline

Topics: Anti-Bacterial Agents; Bacillus; Chloramphenicol; Communicable Diseases; Humans; Pneumonia; Respiratory Tract Infections; Streptomycin; Tetracycline

Topics: Anti-Bacterial Agents; Penicillins; Pneumonia; Pneumonia, Pneumococcal; Tetracycline

Topics: Anti-Bacterial Agents; Humans; Penicillins; Pneumonia; Tetracycline

Topics: Anti-Bacterial Agents; Lung Diseases; Micrococcus; Pneumonia; Tetracycline; Urinary Tract Infections

Topics: Anti-Bacterial Agents; Child; Humans; Infant; Pneumonia; Pneumonia, Bacterial; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Pneumonia; Pneumonia, Pneumococcal; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Bacteriology; Klebsiella; Klebsiella Infections; Pneumonia; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Pneumonia; Tetracycline

Topics: Animals; Goats; Pneumonia; Pneumonia, Mycoplasma; Protein Synthesis Inhibitors; Respiratory Tract Infections; Tetracycline