Scrofuloderma

Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.

Synonym
Scrofuloderma
Tuberculosis, Cutaneous
Skin Tuberculosis
Tuberculid

Excerpt	Reference
"Scrofuloderma is tuberculosis of subcutaneous tissue that ulcerates and drains through the overlying skin."	( Connolly, B; Devine, J; Pitcher, JD; Roth, B; Youngberg, RA, 1999)
"Scrofuloderma is a form of colliquative cutaneous tuberculosis resulting from the spread of an underlying focus, generally represented by lymphnodes; osteoarticular tubercular locations or epididimus locations can also lead to ulcerative cutaneous involvement."	( Cavalchini, A; Clapasson, A; Forgione, P; Langella, M; Nunzi, E; Piccirillo, F; Raimondo, U; Vendemmia, S, 2004)
"Scrofuloderma is a frequent manifestation of cutaneous tuberculosis in Indian scenario."	( Gangane, N; Kar, S; Krishnan, A; Preetha, K, 2011)
"Most cases of cutaneous tuberculosis are symptom free, but tuberculous cellulitis is sometimes painful."	( Chishiki, M; Horinosono, H; Kawakubo, Y; Maeshima, H; Sakiyama, M, 2016)
"The diagnosis of cutaneous tuberculosis is challenging and requires the correlation of clinical findings with often inconclusive diagnostic testing."	( Laidler, N, 2017)
"Scrofuloderma is an endogenous form of cutaneous tuberculosis and can present as isolated or coexist with pulmonary and disseminated forms of tuberculosis."	( Tadele, H, 2018)

Excerpt	Reference
"A case of penis tuberculid (papulonecrotic tuberculid of the glans penis) and its treatment with combination of oral rifampicin (RFP) and injection of an extract from tubercle bacilli (T."	( Aoki, M; Kanamori, S; Nakamura, S; Nakayama, K; Onda, S, 1989)
"Recommendations for the treatment of cutaneous tuberculosis are made."	( Ormerod, LP; Yates, VM, 1997)
"We report a case of cutaneous tuberculosis associated with steroid therapy for mixed connective tissue disease."	( Mizutani, F; Saitou, M; Sakao, S; Sasaki, Y; Tada, Y; Yagi, T; Yamagishi, F, 1998)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	387 (70.88)	23.3326
1990's	40 (7.33)	12.5806
2000's	50 (9.16)	18.1394
2010's	57 (10.44)	28.8240
2020's	12 (2.20)	9.53

Drug	Relationship Strength	Studies	Trials
acetone	low	1	0
ammonium hydroxide	low	1	0
quinacrine	low	1	0
benzoic acid	low	1	0
bromide	low	1	0
chlorine	low	1	0
salicylic acid	low	4	0
formaldehyde	low	2	0
glycine	low	1	0
nickel	low	1	0
niacin	low	69	0
4-aminobenzoic acid	low	1	0
pyrazinamide	medium	34	1
pyridoxine	medium	5	1
acetaminophen	low	1	0
alendronate	low	1	0
aspirin	low	1	0
aurintricarboxylic acid	low	1	0
chloroquine	low	1	0
ciprofloxacin	low	2	0
dapsone	low	5	0
gentamicin	low	1	0
isoniazid	medium	178	2
ketoconazole	low	1	0
khellin	low	2	0
loxoprofen	low	1	0
mebendazole	low	1	0
methadone	low	1	0
niclosamide	low	1	0
ofloxacin	low	1	0
aminosalicylic acid	low	21	0
phenacetin	low	1	0
potassium iodide	low	1	0
procarbazine	low	1	0
aurin	low	1	0
sulfadiazine	low	1	0
sulfamethoxazole	low	1	0
sulfanilamide	low	1	0
sulfasalazine	low	3	0
sulfoxone	low	1	0
trimethoprim	low	2	0
usnic acid	low	1	0
prednisolone	low	10	0
thymidine	low	6	0
prednisone	low	7	0
penicillin g	low	1	0
ethinyl estradiol	low	1	0
carbostyril	low	1	0
tyrosine	low	1	0
fluocinolone acetonide	low	1	0
cycloserine	low	6	0
tryptophan	low	1	0
triamcinolone acetonide	low	1	0
methylprednisolone	low	3	0
cyacetacide	low	1	0
fluocortolone	low	1	0
acridines	low	1	0
thiazoles	low	4	0
pyrazines	low	1	0
hydrazine	low	6	0
fluocinonide	low	1	0
cyanoacetic acid	low	2	0
thiazosulfone	low	2	0
fusarium	low	1	0
emetine	low	1	0
nicotinic acid hydrazide	low	1	0
ethambutol	medium	35	1
potassium hydroxide	low	1	0
vancomycin	low	1	0
benzophenoneidum	low	1	0
streptomycin	medium	69	1
dihydrostreptomycin sulfate	low	3	0
bromine	low	1	0
silver nitrate	low	1	0
trolamine salicylate	low	6	0
gallium chloride	low	1	0
ornidazole	low	1	0
fluorides	low	1	0
iodine	low	1	0
phenyl acetate	low	2	0
triamcinolone	low	1	0
etoposide	low	1	0
amikacin	low	1	0
fomesafen	low	1	0
itraconazole	low	4	0
sulfadiazine, trimethoprim drug combination	low	1	0
fluorodeoxyglucose f18	low	2	0
morphazinamide	low	1	0
enrofloxacin	low	1	0
voriconazole	low	1	0
clarithromycin	low	10	0
nsc-172755	low	1	0
cobalt	low	1	0
asiaticoside	low	1	0
methotrexate	low	3	0
moxifloxacin	low	2	0
tetraphenylphosphonium	low	1	0
cortisone	low	8	0
benzofurans	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	3	0
glycogen	low	1	0
glucosamine	low	1	0
elastin	low	2	0
linezolid	low	1	0
ergosterol	low	2	0
retinol	low	3	0
tacrolimus	low	1	0
zithromax	low	1	0
glucosulfone	low	1	0
phenylthiourea	low	1	0
terbinafine	low	1	0
ethionamide	low	2	0
thiocarlide	low	1	0
ovalbumin	low	1	0
17-ketosteroids	low	1	0
vitamin k semiquinone radical	low	1	0
vitamin d 2	low	54	0
amphotericin b	low	2	0
mycolactone	low	1	0
phenylephrine hydrochloride	low	9	0
hydromorphone	low	1	0
antimony	low	1	0
gallium	low	1	0
indolylacryloylglycine	low	1	0
beryllium	low	1	0
phosphorus	low	1	0
thioacetazone	medium	9	1
amoxicillin-potassium clavulanate combination	low	1	0
rifamycins	low	1	0
acid phosphatase	low	2	0
sodium ethylxanthate	low	1	0
glycolipids	low	1	0
interleukin-8	low	1	0
ascorbic acid	low	5	0
tetracycline	low	3	0
oxytetracycline, anhydrous	medium	2	1
minocycline	low	4	0
tigecycline	low	1	0
transforming growth factor beta	low	2	0
lewis x antigen	low	1	0
hyaluronoglucosaminidase	low	2	0
norgestrel	low	1	0
rifampin	medium	74	1
trypan blue	low	2	0
3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin	low	1	0
trifazid	low	1	0
eye	low	4	0

Protein Targets (1,028)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
DNA-directed RNA polymerase subunit beta	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	15	0	0	15
Genome polyprotein	0	0	1	1
USP1 protein, partial	19	0	0	19
AR protein	36	0	0	36
thyroid stimulating hormone receptor	20	0	0	20
glucocorticoid receptor [Homo sapiens]	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
estrogen nuclear receptor alpha	52	0	0	52
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
Histone H2A.x	13	0	0	13
chromobox protein homolog 1	22	0	0	22
transcriptional regulator ERG isoform 3	4	0	0	4
geminin	31	0	0	31
Polyphenol oxidase 2	0	9	0	12
Cellular tumor antigen p53	22	0	0	22
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
RAR-related orphan receptor gamma	28	0	0	28
ATAD5 protein, partial	14	0	0	14
GLS protein	13	0	0	13
Microtubule-associated protein tau	15	0	0	15
Smad3	11	0	0	11
aldehyde dehydrogenase 1 family, member A1	27	0	0	27
nuclear receptor subfamily 1, group I, member 3	24	0	0	24
progesterone receptor	19	0	0	19
EWS/FLI fusion protein	16	0	0	16
retinoid X nuclear receptor alpha	25	0	0	25
estrogen-related nuclear receptor alpha	39	0	0	39
peroxisome proliferator activated receptor gamma	20	0	0	20
aryl hydrocarbon receptor	13	0	0	13
thyroid hormone receptor beta isoform 2	25	0	0	25
peripheral myelin protein 22	16	0	0	16
cytochrome P450 3A4 isoform 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit pi	15	2	0	17
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	35
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	4	0	6
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	13	0	13
Voltage-dependent calcium channel gamma-2 subunit	11	0	0	11
Bile salt export pump	0	48	0	48
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	18	0	21
Carbonic anhydrase 2	0	18	2	23
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	7	0	10
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 3	0	4	0	6
Cytochrome P450 3A4	0	17	0	19
Cytochrome P450 2D6	0	7	0	8
Cytochrome P450 2C9	0	15	1	17
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	15	2	0	17
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	15	2	0	17
Gamma-aminobutyric acid receptor subunit gamma-2	15	2	0	17
UDP-glucuronosyltransferase 1-6	0	1	0	2
Glutamate receptor 2	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-5	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-3	15	2	0	17
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	6
Carbonic anhydrase 4	0	9	0	11
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	6	0	8
Gamma-aminobutyric acid receptor subunit gamma-1	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-2	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-4	15	2	0	17
Gamma-aminobutyric acid receptor subunit gamma-3	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-6	15	2	0	17
Carbonic anhydrase 5A, mitochondrial	0	6	0	9
Prostaglandin G/H synthase 2	0	5	0	6
Carbonic anhydrase 7	0	4	0	6
Nuclear receptor ROR-gamma	11	0	0	11
Cytochrome P450 2J2	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	15	3	0	18
Gamma-aminobutyric acid receptor subunit beta-3	15	2	0	17
Gamma-aminobutyric acid receptor subunit beta-2	15	2	0	17
Carbonic anhydrase 9	0	6	0	8
GABA theta subunit	15	2	0	17
Canalicular multispecific organic anion transporter 1	0	34	0	35
Carbonic anhydrase 15	0	7	0	9
Carbonic anhydrase 13	0	3	0	4
Gamma-aminobutyric acid receptor subunit epsilon	15	2	0	17
Carbonic anhydrase 14	0	4	0	6
Carbonic anhydrase 5B, mitochondrial	0	4	0	7
toxin B	0	0	0	1
TDP1 protein	30	0	0	30
lamin isoform A-delta10	26	0	0	26
Chain A, Ferritin light chain	7	0	0	7
thioredoxin reductase	19	0	0	19
alpha-galactosidase	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
flap endonuclease 1	11	0	0	11
DNA polymerase iota isoform a (long)	13	0	0	13
DNA topoisomerase 2-alpha	0	2	1	13
Acetylcholinesterase	0	5	0	5
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
histone acetyltransferase KAT2A isoform 1	11	0	0	11
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
thioredoxin glutathione reductase	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	29	0	0	29
microphthalmia-associated transcription factor isoform 9	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	4
Chain A, HADH2 protein	14	0	0	14
Chain B, HADH2 protein	14	0	0	14
Chain A, Cruzipain	8	0	0	8
interleukin 8	11	0	0	11
phosphopantetheinyl transferase	8	0	0	8
farnesoid X nuclear receptor	14	0	0	14
peroxisome proliferator-activated receptor delta	17	0	0	17
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 1	28	0	0	28
Cytochrome P450 2C19	0	7	0	8
Potassium voltage-gated channel subfamily H member 2	0	14	0	16
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	5
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	9	0	0	9
GLI family zinc finger 3	32	0	0	32
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
IDH1	14	0	0	14
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
lethal factor (plasmid)	9	0	0	9
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	4
Alpha-2B adrenergic receptor	0	7	1	8
Spike glycoprotein	9	2	2	13
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	6	0	0	6
glucocerebrosidase	1	0	0	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Bloom syndrome protein isoform 1	9	0	0	9
DNA polymerase kappa isoform 1	8	0	0	8
muscarinic acetylcholine receptor M1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	5	1	6
Sigma non-opioid intracellular receptor 1	0	1	1	2
PAX8	0	0	0	1
glp-1 receptor, partial	10	0	0	10
BRCA1	1	0	0	1
15-lipoxygenase, partial	7	0	0	7
Microphthalmia-associated transcription factor	0	0	0	1
regulator of G-protein signaling 4	8	0	0	8
nonstructural protein 1	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
P53	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
cellular tumor antigen p53 isoform a	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
ras-related protein Rab-9A	5	0	0	5
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
nuclear receptor ROR-gamma isoform 1	9	0	0	9
survival motor neuron protein isoform d	8	0	0	8
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Glycoprotein hormones alpha chain	2	0	0	2
Microtubule-associated protein tau	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	0	1	1
Histamine H2 receptor	10	0	0	10
Solute carrier organic anion transporter family member 1B3	0	10	0	12
Solute carrier organic anion transporter family member 1B1	0	10	0	11
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Chain A, Beta-lactamase	9	0	0	9
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Luciferase	12	0	0	12
endonuclease IV	5	0	0	5
RGS12	1	0	0	1
ClpP	2	0	0	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Thrombopoietin	2	0	0	2
DNA polymerase III, partial	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
nonstructural protein 1	5	0	0	5
cytochrome P450 2D6 isoform 1	4	0	0	4
galactokinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
peripheral myelin protein 22 isoform 1	5	0	0	5
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
cytochrome P450 2C19 precursor	6	0	0	6
cytochrome P450 2C9 precursor	7	0	0	7
runt-related transcription factor 1 isoform AML1b	1	0	0	1
thyroid hormone receptor beta isoform a	6	0	0	6
glucokinase regulatory protein	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
DNA polymerase beta	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
eyes absent homolog 2 isoform a	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase eta isoform 1	3	0	0	3
M-phase phosphoprotein 8	7	0	0	7
pyruvate kinase PKM isoform b	2	0	0	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	0	2
Myc proto-oncogene protein	0	1	0	1
Complement component C9	0	1	0	1
Ornithine decarboxylase	2	0	0	2
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	4	0	4
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Cruzipain	0	1	0	1
DNA-(apurinic or apyrimidinic site) endonuclease	0	1	0	1
DNA-3-methyladenine glycosylase	0	1	0	1
Ribonuclease T	0	0	0	1
Cystathionine gamma-lyase	0	3	1	5
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	3	0	3
Cystathionine beta-synthase	0	1	0	1
Alpha-synuclein	2	3	0	5
Kappa-type opioid receptor	0	1	0	2
DNA repair protein RAD52 homolog	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 3	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	4	0	4
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Inositol monophosphatase 1	2	0	0	2
Cell death-related nuclease 4	0	0	0	1
Thiosulfate sulfurtransferase	0	4	0	4
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Cystathionine gamma-lyase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
DNA polymerase iota	0	1	0	1
DNA polymerase eta	0	1	0	1
Cysteine protease ATG4B	0	1	0	1
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
large T antigen	0	1	0	1
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase	0	1	0	1
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase	0	1	0	1
estrogen receptor 2 (ER beta)	13	0	0	13
D-amino-acid oxidase	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	4	1	0	5
Neuronal acetylcholine receptor subunit beta-2	4	1	0	5
D-amino-acid oxidase	0	3	1	4
Metabotropic glutamate receptor 5	0	0	1	1
Alpha-glucosidase MAL12	0	1	0	1
Monocarboxylate transporter 1	0	0	0	1
Beta-lactamase	0	1	1	3
D-aspartate oxidase	0	2	0	2
Serine racemase	0	2	0	2
pregnane X receptor	6	0	0	6
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
caspase 7, apoptosis-related cysteine protease	3	0	0	3
pregnane X nuclear receptor	28	0	0	28
caspase-3	3	0	0	3
thyrotropin-releasing hormone receptor	2	0	0	2
hemoglobin subunit beta	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
mitogen-activated protein kinase 1	8	0	0	8
Carbonic anhydrase	0	5	0	7
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
PPM1D protein	7	0	0	7
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	2	2	4
Replicase polyprotein 1ab	0	2	3	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	2	2	4
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Interferon beta	19	0	0	19
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	2	2
Amyloid-beta precursor protein	0	3	0	3
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	2	4
Muscarinic acetylcholine receptor M2	0	8	0	8
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	12	0	12
Replicase polyprotein 1a	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Replicase polyprotein 1ab	0	3	2	5
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	4	2	6
Muscarinic acetylcholine receptor M1	0	5	0	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	7	0	7
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Ataxin-2	16	0	0	16
Angiotensin-converting enzyme 2	0	2	2	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	5	0	9
DNA gyrase subunit B	0	5	0	9
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	5	0	7
DNA gyrase subunit A	0	5	0	7
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
streptokinase A precursor	0	0	6	6
ATP-dependent translocase ABCB1	0	9	2	13
dopamine D1 receptor	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
heat shock protein beta-1	10	0	0	10
Glucocorticoid receptor	0	18	2	25
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	18	0	18
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	18	0	18
Glycine receptor subunit alpha-2	0	18	0	18
Glycine receptor subunit alpha-3	0	18	0	18
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Multidrug and toxin extrusion protein 1	0	4	0	4
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	2	8
Glutamate receptor ionotropic, NMDA 2A	0	3	2	8
Glutamate receptor ionotropic, NMDA 2B	0	3	2	8
Glutamate receptor ionotropic, NMDA 2C	0	3	2	8
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	3	2	8
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	3	2	8
Glutamate receptor ionotropic, NMDA 3A	0	3	2	8
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
G	13	0	0	13
67.9K protein	9	0	0	9
muscleblind-like protein 1 isoform 1	5	0	0	5
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Dihydrofolate reductase	0	6	0	7
5-hydroxytryptamine receptor 6	0	1	0	1
Inositol hexakisphosphate kinase 1	13	0	0	13
cytochrome P450 2C9, partial	13	0	0	13
NS5	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
Parkin	2	0	0	2
activating transcription factor 6	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	2
Dihydroorotate dehydrogenase	0	1	0	1
ATPase family AAA domain-containing protein 5	13	0	0	13
Endothelial PAS domain-containing protein 1	0	1	0	2
Nitric oxide synthase, inducible	0	1	0	1
Pantothenate synthetase	0	2	0	2
Fumarate hydratase	6	0	0	6
polyprotein	6	0	0	6
thyroid stimulating hormone receptor	12	0	0	12
lysosomal alpha-glucosidase preproprotein	4	0	0	4
Vpr	2	0	0	2
Solute carrier family 22 member 2	0	1	0	1
Estrogen receptor	0	4	1	5
Aldo-keto reductase family 1 member B1	0	10	0	10
Adenosine receptor A3	0	2	0	2
Androgen receptor	0	7	0	7
Alpha-1B adrenergic receptor	0	4	0	4
Cytochrome P450 2B6	0	3	1	4
Sodium-dependent noradrenaline transporter	0	10	1	11
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Sodium-dependent serotonin transporter	0	6	1	7
Mu-type opioid receptor	0	5	1	6
Kappa-type opioid receptor	0	4	1	5
Alpha-1A adrenergic receptor	0	4	0	4
Sulfotransferase 1A1	0	2	1	4
Sodium-dependent dopamine transporter	0	6	1	7
Aldehyde oxidase	0	2	0	2
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Estrogen receptor beta	0	3	1	4
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	3	0	3
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 3	0	0	0	1
Delta-type opioid receptor	0	4	0	4
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Endonuclease 8-like 1	0	1	0	1
GALC protein	5	0	0	5
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Aromatase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	2
Substance-K receptor	0	2	0	2
Thromboxane-A synthase	0	2	0	2
Histamine H2 receptor	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Lanosterol 14-alpha demethylase	0	3	1	4
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
30S ribosomal protein S6	0	3	0	3
30S ribosomal protein S7	0	3	0	3
50S ribosomal protein L15	0	3	0	3
Estrogen receptor	0	0	1	1
50S ribosomal protein L10	0	3	0	3
50S ribosomal protein L11	0	3	0	3
50S ribosomal protein L7/L12	0	3	0	3
50S ribosomal protein L19	0	3	0	3
50S ribosomal protein L1	0	3	0	3
50S ribosomal protein L20	0	3	0	3
50S ribosomal protein L27	0	3	0	3
50S ribosomal protein L28	0	3	0	3
50S ribosomal protein L29	0	3	0	3
50S ribosomal protein L31	0	3	0	3
50S ribosomal protein L31 type B	0	3	0	3
50S ribosomal protein L32	0	3	0	3
50S ribosomal protein L33	0	3	0	3
50S ribosomal protein L34	0	3	0	3
50S ribosomal protein L35	0	3	0	3
50S ribosomal protein L36	0	3	0	3
30S ribosomal protein S10	0	3	0	3
30S ribosomal protein S11	0	3	0	3
30S ribosomal protein S12	0	3	0	3
30S ribosomal protein S13	0	3	0	3
30S ribosomal protein S16	0	3	0	3
30S ribosomal protein S18	0	3	0	3
30S ribosomal protein S19	0	3	0	3
30S ribosomal protein S20	0	3	0	3
30S ribosomal protein S2	0	3	0	3
30S ribosomal protein S3	0	3	0	3
30S ribosomal protein S4	0	3	0	3
30S ribosomal protein S5	0	3	0	3
30S ribosomal protein S8	0	3	0	3
30S ribosomal protein S9	0	3	0	3
50S ribosomal protein L13	0	3	0	3
50S ribosomal protein L14	0	3	0	3
50S ribosomal protein L16	0	3	0	3
50S ribosomal protein L23	0	3	0	3
30S ribosomal protein S15	0	3	0	3
50S ribosomal protein L17	0	3	0	3
50S ribosomal protein L21	0	3	0	3
50S ribosomal protein L30	0	3	0	3
50S ribosomal protein L6	0	3	0	3
30S ribosomal protein S14	0	3	0	3
30S ribosomal protein S17	0	3	0	3
30S ribosomal protein S1	0	3	0	3
50S ribosomal protein L18	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
50S ribosomal protein L2	0	3	0	3
50S ribosomal protein L3	0	3	0	3
50S ribosomal protein L24	0	3	0	3
50S ribosomal protein L4	0	3	0	3
50S ribosomal protein L22	0	3	0	3
50S ribosomal protein L5	0	3	0	3
30S ribosomal protein S21	0	3	0	3
50S ribosomal protein L25	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
50S ribosomal protein L36 2	0	3	0	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	1	1
Renin	0	1	0	1
arylsulfatase A	7	0	0	7
huntingtin isoform 2	3	0	0	3
histone deacetylase 9 isoform 3	4	0	0	4
Tyrosine-protein kinase ABL1	0	3	1	4
Methionine aminopeptidase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	3	0	3
Vascular endothelial growth factor receptor 2	0	2	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Calmodulin-domain protein kinase 1	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(4) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	3	0	3
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	6	0	7
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Thymidylate synthase	0	2	0	3
5-hydroxytryptamine receptor 2C	0	2	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	4	2	6
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Multidrug resistance-associated protein 1	0	0	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	3
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Solute carrier family 22 member 8	0	2	0	4
Dihydrofolate reductase	0	2	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	2
Protein-arginine deiminase type-4	0	9	0	9
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Albumin	0	1	4	5
Stromelysin-1	0	3	1	4
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Cholesteryl ester transfer protein	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
Hydroxycarboxylic acid receptor 2	0	1	1	2
TSHR protein	1	0	0	1
PINK1	1	0	0	1
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
D(1A) dopamine receptor	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Aurora kinase A	0	2	0	2
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase Lyn	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Mitogen-activated protein kinase 1	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Mitogen-activated protein kinase 8	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
D(1A) dopamine receptor	3	0	0	3
Guanine nucleotide-binding protein G	2	0	0	2
Angiopoietin-1 receptor	0	1	0	1
Anoctamin-1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Rap guanine nucleotide exchange factor 3	4	0	0	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase VIM-1	0	0	0	1
Cytochrome P450 1A2	0	0	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Arylacetamide deacetylase	0	1	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain A, PROTEIN (CATECHOL OXIDASE)	0	1	0	1
Tyrosinase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Pyridoxal kinase	0	0	0	1
N	0	1	0	1
NPYLR7B	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	2	0	2
tumor susceptibility gene 101 protein	1	0	0	1
Glutathione reductase, mitochondrial	0	1	0	1
Major prion protein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	2	0	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	4	0	4
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Cholinesterase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	5	0	5
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Caspase-1	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier organic anion transporter family member 1A2	0	2	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
D(4) dopamine receptor	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 5	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Transporter	0	2	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protease	0	1	1	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 4	0	1	0	1
Protein argonaute-2	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
C-8 sterol isomerase	0	1	0	1
Squalene monooxygenase	0	1	0	1
Squalene monooxygenase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, Multidrug-efflux Transporter 1 Regulator Bmrr	0	0	1	1
Hydrolase, alpha/beta hydrolase fold family	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase, cytosolic	0	2	0	4
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
NFKB1 protein, partial	2	0	0	2
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Vitamin D3 receptor	0	0	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (546)

Protein Targets (1,028)

Scrofuloderma

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (546)

Drugs Studied (175)

Protein Targets (1,028)