Constitutional Liver Dysfunction

A benign familial disorder, transmitted as an autosomal dominant trait. It is characterized by low-grade chronic hyperbilirubinemia with considerable daily fluctuations of the bilirubin level.

Synonym
Gilbert-Lereboullet Syndrome
Unconjugated Benign Bilirubinemia
Familial Nonhemolytic Jaundice
Hyperbilirubinemia, Arias Type
Hyperbilirubinemia 1
Hyperbilirubinemia I
Meulengracht Syndrome
Gilbert's Disease
Gilbert Disease
Gilbert's Syndrome
Constitutional Liver Dysfunction
Gilbert Syndrome

Excerpt	Reference
"Gilbert's syndrome is typically associated with a deficiency in hepatic bilirubin UDP-glucuronosyltransferase activity (B-GTA)."	( Berthelot, P; Dhumeaux, D, 1978)
"Gilbert's Syndrome is a benign familial condition in which unconjugated hyperbilirubinemia occurs in the absence of structural liver disease or hemolysis."	( Dorevitch, A; Durst, R; Jabotinsky-Rubin, K; Kikinzon, L; Tur-Kaspa, R, 1993)
"Gilbert's syndrome is a benign, often familial condition characterized by recurrent but asymptomatic jaundice."	( Casimiro Peytavi, C; Díaz-Rubio, M; García Paredes, J; Larrubia Marfil, JR; Mendoza Hernández, JL, 1997)
"Gilbert's syndrome is a benign, often familial condition characterized by asymptomatic jaundice."	( Chen, YC; Chiou, TJ; Yang, MH; Yu, IT, 2002)
"Gilbert's syndrome is not a factor to be considered when prescribing morphine."	( Darimont, J; Geisslinger, G; Lötsch, J; Schmidt, H; Skarke, C, 2003)
"Gilbert syndrome is caused by defects in the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) gene."	( Ismail, NZ; Ismail, WP; Matsuo, M; Nishio, H; Ramli, N; Talib, NA; Van Rostenberghe, H; Yusoff, NM; Yusoff, S, 2006)
"Gilbert's syndrome is a common inherited disorder, in which genetic defects in uridine diphosphate-glucuronosyltransferase 1A1 lead to deficient glucuronidation of bilirubin and hence hyperbilirubinaemia."	( Jones, G; Lee, P; Seibel, MJ, 2007)
"Gilbert's syndrome is characterized by a functional promoter single nucleotide polymorphism (SNP) of the UDP-glucuronosyltransferase (UGT) 1A1 gene and represents a pharmacogenetic risk factor for irinotecan toxicity, but study data remain controversial."	( Erichsen, TJ; Heinemann, V; Lankisch, TO; Manns, MP; Schulz, C; Strassburg, CP; Zwingers, T, 2008)
"Gilbert's syndrome is characterized by mild unconjugated nonhemolytic hyperbilirubinemia, which does not lead to hepatic inflammation, fibrosis, chronic liver disease or liver failure."	( Strassburg, CP, 2008)
"Gilbert disease is a benign disorder of the bilirubin conjugation, which affects 7-10% of the average population."	( Faragó, B; Melegh, B, 2008)
"Gilbert's syndrome is a frequent genetic conjugation abnormality associated with adverse drug effects."	( Behrens, G; Ehmer, U; Freiberg, N; Kalthoff, S; Lankisch, TO; Manns, MP; Möbius, U; Rockstroh, J; Schmidt, RE; Strassburg, CP; Wehmeier, M, 2009)
"Gilbert's syndrome is the most common hereditary disorder of bilirubin metabolism."	( Mlakar, SJ; Ostanek, B, 2011)
"Gilbert syndrome is an autosomal recessive condition that is a common cause of nonhemolytic unconjugated hyperbilirubinemia, and its prevalence is 3% to 10% in the healthy US population."	( Akyildiz, M; Dayangac, M; Demirbas, T; Piskin, T; Tokat, Y; Yaprak, O; Yuzer, Y, 2012)
"The Gilbert syndrome is a benign form of unconjugated hyperbilirubinemia, mainly associated with alterations in UGT1A1 gene."	( Bronze-da-Rocha, E; Costa, E; de Carvalho, J; Rodrigues, C; Santos, R; Santos-Silva, A; Vieira, E, 2012)
"Gilbert's syndrome is a common metabolic dysfunction characterized by elevated levels of unconjugated bilirubin in the bloodstream."	( Abramov, ME; Chudinov, AV; Fesenko, EE; Heydarov, RN; Mikhailovich, VM; Stepanova, EV; Zasedatelev, AS, 2013)
"Gilbert's syndrome is a congenital disorder characterized by intermittent and non-hemolytic elevation of indirect bilirubin levels due to the deficiency of the enzyme UDP-glucuronyl transferase in the liver and many prospective studies found an inverse relationship between bilirubin levels and cardiovascular events in these patients."	( Arslan, E; Ay, SA; Bulucu, F; Çakar, M; Demirbaş, S; Karaman, M; Kılınç, A; Sağlam, K; Şarlak, H, 2013)
"Gilbert's syndrome is a common familial hyperbilirubinemia that may reduce the risk of various age-related diseases because of the antioxidant properties of bilirubin."	( Horsfall, LJ; Nazareth, I; Pereira, SP; Petersen, I, 2013)
"Gilbert syndrome is characterized by mild unconjugated hyperbilirubinemia."	( Colah, RB; Dabke, PS; Ghosh, KK; Nadkarni, AH, 2014)
"Gilbert's Syndrome is associated with mutation in the Uridine Glucuronosyl Transferase 1A1 (UGT1A1) gene promoter, reducing UGT1A1 activity, which normally conjugates bilirubin allowing its elimination from the blood."	( Bulmer, AC; Kundur, AR; Singh, I, 2015)
"Gilbert's syndrome is a rather common and, in most cases, asymptomatic congenital metabolic aberration with a prevalence of about 5 %."	( Gunsilius, L; Huppertz, LM; Lardi, C; Thierauf-Emberger, A; Weinmann, W, 2015)
"Gilbert's syndrome is a benign condition characterized by asymptomatic sporadic episodes of jaundice, due to a mild unconjugated hyperbilirubinemia caused by a deficiency in bilirubin glucoronidation."	( Arredondo-Saldaña, G; Bosques-Padilla, F; Flores-Villalba, E; Rodriguez-Montalvo, C; Torre-Flores, L; Zertuche-Maldonado, T, 2016)
"Gilbert syndrome is an autosomal recessive condition that is a common cause of isolated unconjugated hyperbilirubinemia, and its prevalence is not negligibly low in the general population."	( Ahn, CS; Ha, TY; Hwang, S; Jung, DH; Kang, WH; Kim, KH; Kim, SH; Kim, WJ; Lee, SG; Moon, DB; Park, GC; Shin, MH; Song, GW; Yoon, YI, 2015)
"Gilbert's syndrome is a common inherited disorder of bilirubin metabolism, characterised by mild, unconjugated hyperbilirubinaemia."	( Evans, AT; Gooley, TA; McCune, JS; McDonald, GB; Ostrow, JD; Schoch, G, 2016)
"Gilbert's syndrome is a relatively common (3-10% prevalence) genetic condition which results in altered hepatic metabolism."	( Cranshaw, T; Paul, MM; Stanbridge, AJ, 2021)
"Gilbert's syndrome is a kind of benign inherited disease of bilirubin binding disorder, mainly due to the homozygous polymorphism A(TA)7TAA in the promoter of the gene for uridine diphosphate -glucuronosyltransferase 1A1 (UGT1A1), which is a TA insertion into the promoter, designated as UGT1A1*28, with UGT activity reduction to 30% of the normal value."	( Sun, FR; Wang, BY; Xiang, GQ, 2021)
"Diagnosis of Gilbert's syndrome is based on the detection of homozygous carriage of an additional TA-repeat in the promoter of the UGT1A1 gene, leading to a decrease in the activity of the UGT enzyme."	( Kokorina, OS; Kondrasheva, EA; Kovaleva, IS; Lapin, SV; Nazarov, VD; Peshkova, NG; Sidorenko, DV; Svatkovskaya, IB; Volnikova, EG, 2022)

Excerpt	Reference
"Subjects with Gilbert's Syndrome have some impairment of lamotrigine elimination but this is unlikely to be clinically important."	( Cohen, AF; Land, G; Peck, AW; Posner, J; Winton, C, 1989)
"Patients with Gilbert's syndrome have deficient UGT*1."	( Cvitkovic, E; Goldwasser, F; Lokiec, F; Mahjoubi, M; Misset, JL; Myara, A; Trivin, F; Wasserman, E, 1997)
"Individuals with Gilbert's syndrome have an enhanced risk for CPT-11 toxicity."	( Cvitkovic, E; Goldwasser, F; Lokiec, F; Mahjoubi, M; Misset, JL; Myara, A; Trivin, F; Wasserman, E, 1997)
"Patients with Gilbert syndrome have an impaired function of the enzyme UGT1A1, responsible for the degradation of 4-OH-estrogens."	( Astolfi, RH; Baracat, EC; Bugano, DD; de Souza, MM; Francisco, AA; Ono-Nita, SK, 2011)
"Patients with Gilbert syndrome have mild unconjugated hyperbilirubinemia."	( Chayama, K; Fujimura, N; Higashi, Y; Idei, N; Iwamoto, Y; Kajikawa, M; Kihara, Y; Maruhashi, T; Matsumoto, T; Mikami, S; Nakashima, A; Noma, K; Soga, J; Takase, B; Tomiyama, H; Yamashina, A, 2012)

Excerpt	Reference
"In 16 patients suffering from Gilbert's syndrome, there was a decrease in the level of serum bilirubin, and increase of D-glucuric-acid output in urine and bromsulphophthalein transport maximum following the treatment of this drug given in 150 mg/day orally for three weeks."	( Gógl, A; Klinger, W; Müller, D; Ruzsa, C; Simon, K; Vezekényi, Z, 1979)
"Nicotinic acid (NA) administration in Gilbert's syndrome (GS) patients promotes an increment of bilirubin and of total iron serum levels, dependent on a defective hepatic bilitranslocase function and on a haemolytic effect of NA."	( Ayala, F; Budillon, G; Gentile, S; Orlando, C; Santoianni, P, 1988)
"It is concluded that in Gilbert's syndrome two weeks of treatment with cimetidine had no effect on liver blood flow or on conjugation mechanisms which were independent of cytochrome P450."	( Deres, M; Kutz, K, 1984)
"We report two patients with uncommon Gilbert's syndrome with severe unconjugated hyperbilirubinemia which was reduced from 200 to 60-90 micromol/L by long-term administration of rifampicin."	( Einarsson, C; Ellis, E; Gumhold, J; Katsika, D; Kylander, C; Lammert, F; Marschall, HU; Nemeth, A; Strassburg, CP; Trauner, M; Wagner, M, 2006)
"This haplotype predisposes to hyperbilirubinemia in ATV treatment and may have an additional role as a pharmacogenomic risk factor for drug therapy."	( Behrens, G; Lankisch, TO; Manns, MP; Moebius, U; Schmidt, RE; Strassburg, CP; Wehmeier, M, 2006)
"In IDV treatment the risk of severe hyperbilirubinemia is associated with genetic variants of the UGT1A3 and UGT1A7 genes in addition to Gilbert's syndrome (UGT1A1*28)."	( Behrens, G; Ehmer, U; Freiberg, N; Kalthoff, S; Lankisch, TO; Manns, MP; Möbius, U; Rockstroh, J; Schmidt, RE; Strassburg, CP; Wehmeier, M, 2009)
"Acute leukemia with coexisting Gilbert's syndrome treated by allogeneic hematopoietic stem cell transplantation (allo-HSCT) is rarely reported."	( Fan, ZP; Jiang, QL; Liu, QF; Meng, FY; Sun, J; Wei, Q; Yu, GP; Zhao, J, 2011)
"Patients with Gilbert's syndrome were defined as having laboratory values before the start of conditioning therapy for unconjugated serum bilirubin concentrations of at least 17·1 μmol/L (≥1 mg/dL), normal conjugated serum bilirubin, and no evidence of hepatitis, cholestasis, or haemolysis."	( Evans, AT; Gooley, TA; McCune, JS; McDonald, GB; Ostrow, JD; Schoch, G, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	194 (41.28)	23.3326
1990's	67 (14.26)	12.5806
2000's	87 (18.51)	18.1394
2010's	95 (20.21)	28.8240
2020's	27 (5.74)	9.53

Drug	Relationship Strength	Studies	Trials
aminolevulinic acid	low	2	0
carbon monoxide	medium	4	1
choline	low	1	0
glycine	low	2	0
methanol	low	1	0
inositol	low	1	0
niacin	low	14	0
4-nitrophenol	low	1	0
pyridoxine	low	1	0
taurine	low	2	0
uric acid	low	3	0
xanthine	low	1	0
phenytoin	low	2	0
acetaminophen	low	8	0
theophylline	low	1	0
antipyrine	medium	6	1
aspirin	low	2	0
azathioprine	low	1	0
busulfan	low	2	0
caffeine	low	2	0
chlordiazepoxide	low	1	0
cimetidine	low	2	0
clofibrate	low	2	0
clofibric acid	low	1	0
debrisoquin	low	2	0
diazepam	low	1	0
droperidol	low	1	0
ethosuximide	low	1	0
etodolac	low	1	0
fentanyl	low	1	0
flavoxate	low	1	0
fluphenazine	low	1	0
fluorouracil	low	3	0
gemfibrozil	low	1	0
glutethimide	low	4	0
indomethacin	low	2	0
iohexol	low	1	0
iopanoic acid	low	1	0
iopromide	low	1	0
lamotrigine	low	2	0
lorazepam	medium	2	1
mebendazole	low	1	0
nitroglycerin	low	1	0
oxazepam	low	1	0
phenobarbital	medium	41	3
phenylbutazone	low	1	0
pirenzepine	low	1	0
propafenone	low	1	0
risperidone	low	1	0
sulfamethazine	low	2	0
sulfamethoxypyridazine	low	1	0
sulfobromophthalein	low	24	0
thiotepa	low	1	0
tolbutamide	low	1	0
prednisolone	low	1	0
thyroxine	low	2	0
spironolactone	low	1	0
penicillamine	low	1	0
prednisone	low	1	0
aspartic acid	low	2	0
lysine	low	1	0
ethinyl estradiol	low	1	0
aminopyrine	low	3	0
uridine	low	3	0
uridine diphosphate	low	2	0
tyrosine	low	1	0
methionine	low	1	0
diethyl sulfate	low	1	0
norethynodrel	low	1	0
cytarabine	low	1	0
mestranol	low	1	0
methandrostenolone	low	1	0
arginine	low	1	0
1-naphthol	low	1	0
cyclohexanol	low	1	0
pyrroles	low	3	0
thiophenes	low	1	0
framycetin	medium	1	1
meglumine	low	1	0
uridine diphosphate glucose	low	1	0
2-naphthol	low	1	0
quinazolines	medium	2	1
indazoles	low	3	0
thiazoles	low	1	0
pyrazines	low	1	0
ethynodiol diacetate	low	1	0
chenodeoxycholic acid	medium	3	1
glycocholic acid	low	3	0
malondialdehyde	low	1	0
lithium carbonate	low	1	0
deoxycytidine	low	1	0
uridine diphosphate xylose	low	1	0
platinum	medium	1	1
technetium	low	1	0
camptothecin	medium	8	1
tricalcium phosphate	low	1	0
urobilinogen	low	1	0
ursodeoxycholic acid	low	2	0
glucaric acid	low	2	0
ribavirin	low	2	0
bezafibrate	low	1	0
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	low	1	0
epirubicin	low	2	0
flumecinol	medium	3	1
lovastatin	low	2	0
simvastatin	low	1	0
pravastatin	low	1	0
duloxetine hydrochloride	low	1	0
irinotecan	medium	8	1
ziprasidone	low	1	0
capecitabine	low	1	0
colestipol	low	1	0
venlafaxine hydrochloride	low	1	0
n-acetylaspartic acid	low	1	0
tribuzone	low	1	0
diazobenzenesulfonic acid	low	1	0
coproporphyrin i	low	1	0
acetaminophen glucuronide	low	1	0
nicotine	low	1	0
homocysteine	low	2	0
glucuronic acid	low	2	0
zinc coproporphyrin iii	low	1	0
n(6)-carboxymethyllysine	low	1	0
tamsulosin	low	1	0
atazanavir sulfate	low	3	0
technetium tc 99m pentetate	low	1	0
4-nitrobenzene diazonium tetrafluoroborate	low	1	0
lapatinib	medium	2	1
lenalidomide	low	1	0
deoxycholic acid	low	1	0
bortezomib	low	1	0
quinidine	low	1	0
tibolone	low	1	0
melphalan	low	1	0
dipyrone	low	1	0
s 1033	low	1	0
digoxin	low	1	0
bilirubin	medium	343	6
hymecromone	low	2	0
bilirubin diglucuronide	low	3	0
tranilast	medium	1	1
isotretinoin	low	5	0
morphine	low	1	0
acipimox	low	1	0
su 11248	low	1	0
indinavir sulfate	low	1	0
cysteine	low	1	0
rifamycin sv	low	3	0
bilirubin ditaurine	low	1	0
desvenlafaxine succinate	low	1	0
mocetinostat	low	1	0
dikalm	low	1	0
pazopanib	low	3	0
indocyanine green	low	10	0
rifamycins	low	4	0
acid phosphatase	low	1	0
oligonucleotides	low	1	0
vx-770	low	1	0
sodium salicylate	low	1	0
ethyl glucuronide	low	1	0
s-adenosylmethionine	medium	1	1
heme	low	11	0
novobiocin	low	2	0
tetracycline	low	1	0
nitrophenols	low	2	0
vitamin b 12	low	2	0
cyclosporine	low	1	0
exudates	low	1	0
levoleucovorin	low	1	0
deoxyguanosine	low	1	0
guanine	low	1	0
folic acid	low	1	0
rifampin	medium	15	1
clozapine	low	1	0
didanosine	low	1	0
olanzapine	low	1	0
allopurinol	low	2	0
8-hydroxy-2'-deoxyguanosine	low	1	0
cholestyramine resin	medium	1	1

Protein Targets (1,852)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Luciferase	22	0	0	22
RAR-related orphan receptor gamma	44	0	0	44
GLI family zinc finger 3	46	0	0	46
AR protein	68	0	0	68
estrogen receptor 2 (ER beta)	32	0	0	32
nuclear receptor subfamily 1, group I, member 3	48	0	0	48
progesterone receptor	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	50	0	0	50
estrogen-related nuclear receptor alpha	58	0	0	58
farnesoid X nuclear receptor	26	0	0	26
pregnane X nuclear receptor	47	0	0	47
estrogen nuclear receptor alpha	72	0	0	72
peroxisome proliferator activated receptor gamma	31	0	0	31
aryl hydrocarbon receptor	23	0	0	23
Histone H2A.x	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 1	48	0	0	48
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
DNA repair and recombination protein RadA	0	0	3	3
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Cytochrome P450 1A2	0	6	0	7
Cytochrome P450 2A6	0	5	1	6
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Glutamate receptor 2	27	0	0	27
Cytochrome P450 2A5	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	6	1	10
MAP kinase-activated protein kinase 2	0	1	4	5
retinoid X nuclear receptor alpha	39	0	0	39
peroxisome proliferator-activated receptor delta	31	0	0	31
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	30	0	0	30
v-jun sarcoma virus 17 oncogene homolog (avian)	27	0	0	27
thyroid hormone receptor beta isoform 2	49	0	0	49
Cellular tumor antigen p53	44	0	0	44
Sulfotransferase 1A1	0	0	0	2
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	2	1	5
Sulfotransferase 2A1	0	0	0	1
Chain A, Sulfotransferase 1A1	0	1	0	1
Chain A, Sulfotransferase 1A1	0	1	0	1
acetylcholinesterase	18	0	0	18
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	20	0	0	20
histone deacetylase 9 isoform 3	4	0	0	4
Endolysin	0	0	1	1
UDP-glucuronosyltransferase 1A4	0	2	1	7
Chain A, Beta-lactamase	13	0	0	13
GLS protein	17	0	0	17
euchromatic histone-lysine N-methyltransferase 2	40	0	0	40
geminin	49	0	0	49
Polyphenol oxidase 2	0	4	0	5
Acetylcholinesterase	0	8	0	8
Prostaglandin G/H synthase 1	0	6	0	6
Sodium-dependent dopamine transporter	0	7	0	7
Prostaglandin G/H synthase 2	0	11	5	17
Xanthine dehydrogenase/oxidase	0	4	0	4
Dehydrogenase/reductase SDR family member 9	0	2	0	2
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
ATAD5 protein, partial	13	0	0	13
Microtubule-associated protein tau	22	0	0	22
Smad3	10	0	0	10
aldehyde dehydrogenase 1 family, member A1	31	0	0	31
thyroid stimulating hormone receptor	21	0	0	21
EWS/FLI fusion protein	41	0	0	41
chromobox protein homolog 1	28	0	0	28
peripheral myelin protein 22	21	0	0	21
cytochrome P450 3A4 isoform 1	21	0	0	21
Gamma-aminobutyric acid receptor subunit pi	21	6	1	28
ATP-binding cassette sub-family C member 3	0	47	0	47
Multidrug resistance-associated protein 4	0	48	0	49
Solute carrier family 22 member 6	0	8	0	8
Carbonic anhydrase 12	0	4	0	5
UDP-glucuronosyltransferase 1A9	0	0	1	2
Bile salt export pump	0	12	0	12
Bile salt export pump	0	69	0	70
Cytochrome P450 2B1	0	2	0	3
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	7	0	9
Carbonic anhydrase 2	0	7	0	9
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 3	0	3	0	4
Cytochrome P450 3A4	0	20	1	24
Cytochrome P450 2D6	0	11	0	12
Cytochrome P450 2C9	0	13	1	15
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	21	6	1	28
Gamma-aminobutyric acid receptor subunit delta	21	6	1	28
Gamma-aminobutyric acid receptor subunit gamma-2	21	6	1	28
UDP-glucuronosyltransferase 1-6	0	2	1	4
Gamma-aminobutyric acid receptor subunit alpha-5	21	6	1	28
Gamma-aminobutyric acid receptor subunit alpha-3	21	6	1	28
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase 6	0	3	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	21	6	1	28
Gamma-aminobutyric acid receptor subunit alpha-2	21	6	1	28
Gamma-aminobutyric acid receptor subunit alpha-4	21	6	1	28
Gamma-aminobutyric acid receptor subunit gamma-3	21	6	1	28
Gamma-aminobutyric acid receptor subunit alpha-6	21	6	1	28
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
Carbonic anhydrase 7	0	3	0	4
Nuclear receptor ROR-gamma	12	1	1	14
Cytochrome P450 2J2	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	21	7	1	29
Gamma-aminobutyric acid receptor subunit beta-3	21	6	1	28
Gamma-aminobutyric acid receptor subunit beta-2	21	6	1	28
Carbonic anhydrase 9	0	5	0	6
GABA theta subunit	21	6	1	28
Canalicular multispecific organic anion transporter 1	0	45	0	45
Carbonic anhydrase 15	0	3	0	4
Carbonic anhydrase 13	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	21	6	1	28
Carbonic anhydrase 14	0	3	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
toxin B	0	0	0	1
cellular tumor antigen p53 isoform a	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Guanine nucleotide-binding protein G	5	0	0	5
Inositol monophosphatase 1	12	0	0	12
Fumarate hydratase	17	0	0	17
polyprotein	17	0	0	17
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Hydroxycarboxylic acid receptor 2	0	2	2	4
interleukin 8	14	0	0	14
TDP1 protein	59	0	0	59
glucocorticoid receptor [Homo sapiens]	52	0	0	52
IDH1	14	0	0	14
Bloom syndrome protein isoform 1	12	0	0	12
transcriptional regulator ERG isoform 3	5	0	0	5
ras-related protein Rab-9A	5	0	0	5
survival motor neuron protein isoform d	19	0	0	19
lamin isoform A-delta10	38	0	0	38
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	7	5	14
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	5
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	14	0	0	14
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Chain A, Ferritin light chain	11	0	0	11
thioredoxin reductase	25	0	0	25
15-lipoxygenase, partial	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	40	0	0	40
G	31	0	0	31
vitamin D (1,25- dihydroxyvitamin D3) receptor	31	0	0	31
activating transcription factor 6	15	0	0	15
thyroid hormone receptor beta isoform a	14	0	0	14
Interferon beta	41	0	0	41
HLA class I histocompatibility antigen, B alpha chain	31	0	0	31
Nicotinate phosphoribosyltransferase	0	5	0	5
Inositol hexakisphosphate kinase 1	31	0	0	31
cytochrome P450 2C9, partial	31	0	0	31
ORF73	0	0	1	1
USP1 protein, partial	19	0	0	19
67.9K protein	14	0	0	14
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	17
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	17	0	0	17
NFKB1 protein, partial	6	0	0	6
alpha-galactosidase	7	0	0	7
cytochrome P450 2C19 precursor	9	0	0	9
flap endonuclease 1	6	0	0	6
DNA polymerase iota isoform a (long)	12	0	0	12
muscarinic acetylcholine receptor M1	16	0	0	16
lethal factor (plasmid)	13	0	0	13
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
ATP-dependent phosphofructokinase	18	0	0	18
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
arylsulfatase A	14	0	0	14
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	5
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	5
Glutamate receptor ionotropic, NMDA 2B	0	3	1	5
Glutamate receptor ionotropic, NMDA 2C	0	3	1	5
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	1	5
Glutamate receptor ionotropic, NMDA 3B	0	3	1	5
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	5
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	25	0	0	25
glucocerebrosidase	9	0	0	9
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
DNA polymerase kappa isoform 1	10	0	0	10
Prostaglandin-H2 D-isomerase	0	2	0	2
Epidermal growth factor receptor	0	8	4	12
Fatty acid-binding protein, liver	0	7	1	8
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	8	0	11
Adenosine receptor A2a	0	6	0	11
Substance-P receptor	0	2	0	2
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	8	1	9
Sigma non-opioid intracellular receptor 1	0	3	1	4
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
thioredoxin glutathione reductase	8	0	0	8
P53	1	0	0	1
thyroid stimulating hormone receptor	13	0	0	13
peripheral myelin protein 22 isoform 1	13	0	0	13
hemoglobin subunit beta	4	0	0	4
heat shock protein beta-1	13	0	0	13
M-phase phosphoprotein 8	9	0	0	9
muscleblind-like protein 1 isoform 1	7	0	0	7
ATPase family AAA domain-containing protein 5	15	0	0	15
Ataxin-2	19	0	0	19
Protein-arginine deiminase type-4	0	2	0	2
D(1A) dopamine receptor	8	0	0	8
Glutamate receptor ionotropic, NMDA 2D	0	0	2	2
Glutamate receptor ionotropic, NMDA 3B	0	0	2	2
5-hydroxytryptamine receptor 4	0	12	2	14
Muscarinic acetylcholine receptor M1	0	6	2	8
Muscarinic acetylcholine receptor M3	0	6	2	8
Muscarinic acetylcholine receptor M4	0	7	2	9
Muscarinic acetylcholine receptor M5	0	6	2	8
Muscarinic acetylcholine receptor M2	0	6	2	8
Fatty acid-binding protein, intestinal	0	2	0	2
Peroxisome proliferator-activated receptor alpha	0	0	3	3
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	7	7
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Peroxisome proliferator-activated receptor delta	0	0	2	2
Glutamate receptor ionotropic, NMDA 1	0	0	2	2
Peroxisome proliferator-activated receptor alpha	0	0	4	4
Glutamate receptor ionotropic, NMDA 2A	0	0	2	2
Glutamate receptor ionotropic, NMDA 2B	0	0	2	2
Glutamate receptor ionotropic, NMDA 2C	0	0	2	2
Glutamate receptor ionotropic, NMDA 3A	0	0	2	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, Cruzipain	8	0	0	8
vitamin D3 receptor isoform VDRA	12	0	0	12
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	11	0	13
Solute carrier organic anion transporter family member 1B1	0	14	0	18
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
PPM1D protein	13	0	0	13
caspase 7, apoptosis-related cysteine protease	9	0	0	9
caspase-3	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	5	0	5
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	1	0	2
Chymotrypsinogen A	0	1	0	1
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Proteasome subunit beta type-1	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	4	5
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	6	0	6
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	6	0	6
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	5	0	5
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
apical membrane antigen 1, AMA1	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
DNA polymerase beta	4	0	0	4
nuclear receptor ROR-gamma isoform 1	16	0	0	16
Potassium channel subfamily K member 2	0	2	4	6
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Cholinesterase	0	3	0	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	4	2	6
Adenosine receptor A3	0	9	0	9
Replicase polyprotein 1ab	0	6	2	8
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	2	0	4
Adenosine receptor A2b	0	4	0	6
Adenosine receptor A1	0	6	2	12
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	2	4	6
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	4	7
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	2	3
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	2	0	2
Muscarinic acetylcholine receptor	0	1	0	2
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	1	7
Guanine deaminase	0	3	0	4
DNA topoisomerase	0	1	0	1
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
regulator of G-protein signaling 4	13	0	0	13
putative alpha-glucosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	6	0	0	6
huntingtin isoform 2	4	0	0	4
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
relaxin receptor 1 isoform 1	1	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	1	5	6
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	1	1	7
DNA topoisomerase 2-alpha	0	2	4	6
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	17	1	18
Type-2 restriction enzyme HindIII	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Histone deacetylase 4	0	3	0	3
Ribonuclease pancreatic	0	2	0	2
DNA topoisomerase 2-beta	0	0	4	5
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	2	0	2
Histone deacetylase 7	0	3	0	3
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	3	0	3
Liver carboxylesterase 1	0	0	0	2
Alpha-2A adrenergic receptor	0	12	2	14
Vitamin D3 receptor	0	3	3	6
Alpha-2B adrenergic receptor	0	13	1	14
Alpha-2C adrenergic receptor	0	14	1	15
Retinoic acid receptor RXR-alpha	0	1	1	2
Ileal sodium/bile acid cotransporter	0	3	0	3
Bile acid receptor	0	0	1	1
G-protein coupled bile acid receptor 1	0	0	4	4
Bile acid receptor	0	1	3	4
glp-1 receptor, partial	11	0	0	11
potassium voltage-gated channel subfamily H member 2 isoform d	20	0	0	20
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	2	6
Translocator protein	0	4	2	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	1	5
5-hydroxytryptamine receptor 1A	0	16	1	17
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-3	0	4	1	5
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	1	5
Histamine H1 receptor	0	14	3	20
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	6	0	8
Solute carrier family 22 member 1	0	11	0	14
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	2	5	2	10
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	2	5	2	10
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	4	3	8
Solute carrier family 22 member 1	0	7	0	9
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Solute carrier family 22 member 2	0	6	0	7
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
ATP-dependent translocase ABCB1	0	14	2	22
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Histamine H2 receptor	0	8	0	8
Histamine H1 receptor	0	3	2	5
Histamine H2 receptor	10	2	1	13
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	2	0	2
Solute carrier family 22 member 6	0	4	0	5
Multidrug and toxin extrusion protein 2	0	5	0	5
Solute carrier family 22 member 8	0	6	0	8
Multidrug and toxin extrusion protein 1	0	9	0	9
Histamine H4 receptor	0	2	1	3
Solute carrier family 22 member 11	0	2	0	3
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	3	0	4
GALC protein	7	0	0	7
cytochrome P450 2D6 isoform 1	10	0	0	10
5-hydroxytryptamine receptor 3E	0	4	0	4
hypoxia-inducible factor 1 alpha subunit	16	0	0	16
Beta-1 adrenergic receptor	0	1	0	1
Adenylate cyclase type 1	0	1	0	1
cytochrome P450 2C9 precursor	8	0	0	8
mitogen-activated protein kinase 1	8	0	0	8
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	4	0	4
Albumin	0	0	4	4
Aldo-keto reductase family 1 member B1	0	13	0	13
Muscarinic acetylcholine receptor M2	0	10	1	11
Muscarinic acetylcholine receptor M4	0	14	1	15
5-hydroxytryptamine receptor 1A	0	7	3	10
5-hydroxytryptamine receptor 2C	0	6	0	6
Muscarinic acetylcholine receptor M5	0	10	0	10
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M1	0	9	3	13
Angiotensin-converting enzyme	0	11	0	11
D(2) dopamine receptor	0	14	0	18
5-hydroxytryptamine receptor 2A	0	7	0	7
Alpha-1B adrenergic receptor	0	13	1	14
Beta-1 adrenergic receptor	0	2	0	2
D	0	5	0	5
D(3) dopamine receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	6	2	8
D(2) dopamine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	11	1	12
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	11	0	12
D(4) dopamine receptor	0	9	0	11
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	5	2	7
Alpha-2A adrenergic receptor	0	5	2	7
Alpha-1D adrenergic receptor	0	8	1	9
Sodium-dependent noradrenaline transporter	0	14	0	14
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Alpha-1D adrenergic receptor	0	14	1	15
D(1B) dopamine receptor	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	14	0	17
5-hydroxytryptamine receptor 2C	0	13	1	14
5-hydroxytryptamine receptor 1B	0	10	0	10
5-hydroxytryptamine receptor 1D	0	2	0	2
D(4) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	6	1	7
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	15	0	15
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	2	0	2
Cytochrome P450 2C19	0	5	0	6
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 7	0	5	0	5
Alpha-1A adrenergic receptor	0	8	2	10
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	7	2	9
D(3) dopamine receptor	0	13	0	15
5-hydroxytryptamine receptor 3A	0	1	0	1
Adenylate cyclase type 8	0	1	0	1
Alpha-1A adrenergic receptor	0	14	1	15
5-hydroxytryptamine receptor 3A	0	4	0	4
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	10	0	11
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	7	0	7
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Spike glycoprotein	25	1	2	28
D(2) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	7	0	7
Calmodulin	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Sodium-dependent dopamine transporter	0	10	0	10
5-hydroxytryptamine receptor 2B	0	2	0	2
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	27	0	27
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	11	0	11
Transporter	0	4	0	4
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	11	0	11
5-hydroxytryptamine receptor 3D	0	4	0	4
Adenylyl cyclase 7	0	1	0	1
5-hydroxytryptamine receptor 3C	0	4	0	4
D	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Transporter	0	4	1	6
Histamine H3 receptor	0	3	0	3
endonuclease IV	3	0	0	3
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	3
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	4	7
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	2	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
Cytochrome P450 2D4	0	2	0	2
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	1
Reverse transcriptase/RNaseH	0	1	1	2
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Gamma-aminobutyric acid	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	8	13
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Translocator protein	0	1	0	1
Translocator protein	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	10	0	0	10
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	4	0	7
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
N-acetyltransferase Eis	0	1	0	1
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
Alpha-synuclein	3	2	0	5
Genome polyprotein	0	1	0	1
Tyrosine-protein kinase Fyn	0	2	4	6
UDP-glucuronosyltransferase 2B7	0	2	1	4
pregnane X receptor	7	0	0	7
Vpr	3	0	0	3
Estrogen receptor	0	10	2	12
Glucocorticoid receptor	0	8	4	17
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Androgen receptor	0	15	0	16
Glycine receptor subunit beta	0	8	0	8
Cytochrome P450 2B6	0	2	1	3
Glycine receptor subunit alpha-2	0	8	0	8
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Glycine receptor subunit alpha-3	0	8	0	8
Mu-type opioid receptor	0	8	2	11
Kappa-type opioid receptor	0	8	1	10
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Estrogen receptor beta	0	4	2	6
neuropeptide S receptor isoform A	4	0	0	4
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 3	0	0	1	3
Potassium voltage-gated channel subfamily KQT member 2	0	0	1	3
UDP-glucuronosyltransferase 2B11	0	0	1	1
UDP-glucuronosyltransferase 2B17	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 2	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 3	0	0	1	1
Sodium channel protein type 2 subunit alpha	0	2	1	3
UDP-glucuronosyltransferase 2B4	0	0	1	1
UDP-glucuronosyltransferase 2A1	0	0	1	1
UDP-glucuronosyltransferase 2A2	0	0	1	1
UDP-glucuronosyltransferase 1A3	0	0	1	2
UDP-glucuronosyltransferase 1A5	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	2	1	3
UDP-glucuronosyltransferase 2B15	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 4	0	0	1	1
UDP-glucuronosyltransferase 2A3	0	0	1	1
UDP-glucuronosyltransferase 2B28	0	0	1	1
UDP-glucuronosyltransferase 1A7	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 5	0	0	1	2
Potassium voltage-gated channel subfamily KQT member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Delta-type opioid receptor	0	4	0	5
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	2	10
Kappa-type opioid receptor	0	3	1	5
Delta-type opioid receptor	0	6	1	8
Kappa-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	3	1	6
Mu-type opioid receptor	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	5	0	5
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	4	0	0	4
Solute carrier family 22 member 8	0	0	0	1
Amyloid-beta precursor protein	1	2	0	3
Aromatase	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Transmembrane protease serine 2	0	1	2	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	4	6
Procathepsin L	0	2	2	4
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Beta-3 adrenergic receptor	0	4	0	4
Substance-K receptor	0	6	0	6
Trypanothione reductase	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	4	0	4
Angiotensin-converting enzyme 2	0	1	2	3
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	1	0	0	1
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	1	3
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	2
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Transthyretin	0	1	1	3
Cytochrome P450 2C8	0	2	0	2
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Proton-coupled amino acid transporter 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	1	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Sodium/bile acid cotransporter	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	5
Bile salt export pump	0	0	0	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	2	0	2
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Acetylcholinesterase	0	2	0	2
Genome polyprotein	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	2	0	2
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Oleandomycin glycosyltransferase	0	0	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Cyclin-dependent kinase 1	0	1	4	5
Heat shock protein HSP 90-alpha	0	0	3	3
G2/mitotic-specific cyclin-B1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	0	1	1
Cyclin-A2	0	1	0	1
Cyclin-dependent kinase 2	0	3	4	7
RAC-alpha serine/threonine-protein kinase	0	2	4	6
Cyclin-A1	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Solute carrier family 22 member 3	0	3	0	3
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Thromboxane-A synthase	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Protease	0	2	1	5
Protease	0	2	1	3
Protease	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	6	0	0	6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	7	0	8
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	4	2	6
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	1	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 7	0	1	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	2
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	4	0	6
DNA gyrase subunit B	0	4	1	6
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	4	0	5
DNA gyrase subunit A	0	4	0	5
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
DNA polymerase eta isoform 1	2	0	0	2
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	4	5
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	1	5	6
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	2	0	4
Potassium voltage-gated channel subfamily KQT member 1	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	8	0	8
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	1	0	1
Chain A, Epidermal growth factor receptor	0	1	0	1
Leukotriene C4 synthase	0	0	4	4
tyrosine-protein kinase Yes	3	0	0	3
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	4	4
Membrane-associated progesterone receptor component 1	0	0	4	4
Cell division cycle 7-related protein kinase	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	4	5
Serine/threonine-protein kinase PLK4	0	1	4	5
Serine/threonine-protein kinase 25	0	0	4	4
ATP-dependent RNA helicase DDX3X	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	4	4
Pyridoxal kinase	0	0	4	5
Citron Rho-interacting kinase	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 7	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	4	4
Peripheral plasma membrane protein CASK	0	0	4	4
Aurora kinase A	0	1	4	5
Cyclin-G-associated kinase	0	0	4	4
Serine/threonine-protein kinase DCLK1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	4	4
Muscle, skeletal receptor tyrosine-protein kinase	0	0	4	4
Ephrin type-B receptor 6	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
Mitogen-activated protein kinase 13	0	0	4	4
3-phosphoinositide-dependent protein kinase 1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 13	0	0	4	4
Death-associated protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 2	0	0	4	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
NUAK family SNF1-like kinase 1	0	1	4	5
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	4	4
Tyrosine-protein kinase JAK2	0	0	4	4
Eukaryotic translation initiation factor 5B	0	0	3	3
Rho-associated protein kinase 2	0	0	4	4
Serine/threonine-protein kinase ULK1	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	4	4
Ribosomal protein S6 kinase alpha-5	0	0	4	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	4	4
Serine/threonine-protein kinase 16	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	4	4
Serine/threonine-protein kinase PAK 3	0	0	4	4
Cyclin-dependent kinase-like 5	0	0	4	4
Serine/threonine-protein kinase 17B	0	0	4	4
Serine/threonine-protein kinase 10	0	0	4	4
Serine/threonine-protein kinase D3	0	0	4	4
Cyclin-dependent kinase 14	0	0	4	4
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	4	4
Serine/threonine-protein kinase LATS1	0	0	4	4
Serine/threonine-protein kinase PAK 4	0	2	4	6
Serine/threonine-protein kinase Chk2	0	1	4	5
Tyrosine-protein kinase ABL1	0	7	5	13
RAF proto-oncogene serine/threonine-protein kinase	0	2	4	6
High affinity nerve growth factor receptor	0	0	4	4
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	3	3
ADP/ATP translocase 2	0	0	4	4
Protein kinase C beta type	0	0	4	4
Insulin receptor	0	2	4	6
Tyrosine-protein kinase Lck	0	3	4	7
Glycogen phosphorylase, liver form	0	0	4	4
Tyrosine-protein kinase Fes/Fps	0	0	4	4
Macrophage colony-stimulating factor 1 receptor	0	3	4	7
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	4	4
Tyrosine-protein kinase Lyn	0	1	4	5
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	4	5
Insulin-like growth factor 1 receptor	0	1	4	5
Signal recognition particle receptor subunit alpha	0	0	4	4
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	1	4	5
Tyrosine-protein kinase HCK	0	2	4	6
Proto-oncogene tyrosine-protein kinase ROS	0	0	4	4
Platelet-derived growth factor receptor beta	0	6	4	10
Tyrosine-protein kinase Fgr	0	0	4	4
Wee1-like protein kinase 2	0	0	4	4
Uncharacterized serine/threonine-protein kinase SBK3	0	0	4	4
Serine/threonine-protein kinase A-Raf	0	0	4	4
Mast/stem cell growth factor receptor Kit	0	6	4	10
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	2	5	8
Serine/threonine-protein kinase pim-1	0	0	4	4
Fibroblast growth factor receptor 1	0	2	4	6
Myosin light chain kinase, smooth muscle	0	0	3	3
Cyclin-dependent kinase 4	0	0	4	4
ADP/ATP translocase 3	0	0	4	4
Inosine-5'-monophosphate dehydrogenase 2	0	0	4	4
Proto-oncogene tyrosine-protein kinase Src	0	5	4	9
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Insulin receptor-related protein	0	0	4	4
Serine/threonine-protein kinase B-raf	0	0	4	4
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	4	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	4	5
Platelet-derived growth factor receptor alpha	0	5	4	9
Tyrosine-protein kinase Fer	0	0	4	4
Protein kinase C alpha type	0	0	4	4
cAMP-dependent protein kinase catalytic subunit alpha	0	0	4	4
Vascular endothelial growth factor receptor 1	0	3	4	7
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	4	4
Casein kinase II subunit alpha'	0	0	4	4
Ras-related protein Rab-6A	0	0	3	3
Serine/threonine-protein kinase MAK	0	0	4	4
Cytochrome P450 3A5	0	1	0	1
Cyclin-dependent kinase 11B	0	0	4	4
Ephrin type-A receptor 1	0	0	4	4
Fibroblast growth factor receptor 2	0	1	4	5
Receptor tyrosine-protein kinase erbB-3	0	0	4	4
Multifunctional protein ADE2	0	0	4	4
Fibroblast growth factor receptor 4	0	0	4	4
Fibroblast growth factor receptor 3	0	0	4	4
cAMP-dependent protein kinase catalytic subunit gamma	0	0	4	4
cAMP-dependent protein kinase catalytic subunit beta	0	0	4	4
Ferrochelatase, mitochondrial	0	0	4	4
Ribosomal protein S6 kinase beta-1	0	0	4	4
Tyrosine-protein kinase JAK1	0	0	4	4
Protein kinase C eta type	0	0	4	4
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	4	4
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Activin receptor type-2A	0	0	4	4
Mitogen-activated protein kinase 3	0	0	4	4
MAP/microtubule affinity-regulating kinase 3	0	0	4	4
Ephrin type-A receptor 2	0	1	4	5
Ephrin type-A receptor 3	0	0	4	4
Ephrin type-A receptor 8	0	0	4	4
Ephrin type-B receptor 2	0	0	4	4
Leukocyte tyrosine kinase receptor	0	0	4	4
Non-receptor tyrosine-protein kinase TYK2	0	0	4	4
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	4	4
Wee1-like protein kinase	0	0	4	4
Heme oxygenase 2	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	1	4	5
Mitogen-activated protein kinase 4	0	0	4	4
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-beta serine/threonine-protein kinase	0	0	4	4
G protein-coupled receptor kinase 4	0	0	4	4
Dual specificity protein kinase TTK	0	0	4	4
DNA replication licensing factor MCM4	0	0	4	4
Myosin-10	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	4	4
Vascular endothelial growth factor receptor 3	0	3	4	7
Vascular endothelial growth factor receptor 2	0	6	4	10
Dual specificity mitogen-activated protein kinase kinase 2	0	0	4	4
Receptor-type tyrosine-protein kinase FLT3	0	2	4	7
Bone morphogenetic protein receptor type-1A	0	0	4	4
Activin receptor type-1B	0	0	4	4
TGF-beta receptor type-1	0	0	4	4
Serine/threonine-protein kinase receptor R3	0	0	4	4
TGF-beta receptor type-2	0	0	4	4
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	4	4
Glycine--tRNA ligase	0	0	4	4
Protein kinase C iota type	0	0	4	4
Exosome RNA helicase MTR4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	4	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	4	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	4	4
Tyrosine-protein kinase Tec	0	0	4	4
Tyrosine-protein kinase TXK	0	0	4	4
Tyrosine-protein kinase ABL2	0	0	4	4
Tyrosine-protein kinase FRK	0	0	4	4
G protein-coupled receptor kinase 6	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	4	4
Tyrosine-protein kinase SYK	0	0	4	4
Mitogen-activated protein kinase 8	0	0	4	4
Mitogen-activated protein kinase 9	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	4	4
Casein kinase I isoform alpha	0	1	4	5
Casein kinase I isoform delta	0	0	4	4
Cyclin-dependent kinase 8	0	0	4	4
Elongation factor Tu, mitochondrial	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	4	4
Casein kinase I isoform epsilon	0	0	4	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	0	4	4
Dual specificity protein kinase CLK2	0	0	4	4
Dual specificity protein kinase CLK3	0	0	4	4
Glycogen synthase kinase-3 alpha	0	0	4	4
Glycogen synthase kinase-3 beta	0	0	4	4
Cyclin-dependent kinase 7	0	0	4	4
Cyclin-dependent kinase 9	0	0	4	4
Ras-related protein Rab-27A	0	0	4	4
Tyrosine-protein kinase Blk	0	1	4	5
Interleukin-1 receptor-associated kinase 1	0	0	4	4
Ribosomal protein S6 kinase alpha-3	0	1	4	5
Cytoplasmic tyrosine-protein kinase BMX	0	0	4	4
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	4	4
Serine/threonine-protein kinase Nek2	0	1	4	5
Serine/threonine-protein kinase Nek3	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	4	4
Tyrosine-protein kinase JAK3	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase PLK1	0	3	4	7
Death-associated protein kinase 1	0	0	4	4
LIM domain kinase 1	0	0	4	4
LIM domain kinase 2	0	0	4	4
Mitogen-activated protein kinase 12	0	0	4	4
Mitogen-activated protein kinase 10	0	0	4	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	4	4
5'-AMP-activated protein kinase subunit gamma-1	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	4	5
Ephrin type-B receptor 3	0	0	4	4
Ephrin type-A receptor 5	0	0	4	4
Ephrin type-B receptor 4	0	1	4	5
Ephrin type-B receptor 1	0	0	4	4
Ephrin type-A receptor 4	0	0	4	4
Adenylate kinase 2, mitochondrial	0	0	4	4
Adenosine kinase	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	4	4
Serine/threonine-protein kinase SIK1	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 4	0	0	4	4
Ras-related protein Rab-10	0	0	4	4
Cell division control protein 2 homolog	0	0	4	4
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
Calcium-dependent protein kinase 1	0	0	4	4
GTP-binding nuclear protein Ran	0	0	4	4
Tubulin alpha-1A chain	0	0	3	3
Casein kinase II subunit alpha	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	4	4
SRSF protein kinase 2	0	0	4	4
Casein kinase I isoform gamma-2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 9	0	0	4	4
Serine/threonine-protein kinase PknB	0	0	4	4
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	4	4
Cyclin-dependent kinase 6	0	0	4	4
Cyclin-dependent-like kinase 5	0	0	4	4
Cyclin-dependent kinase 16	0	0	4	4
Cyclin-dependent kinase 17	0	0	4	4
ATP-dependent 6-phosphofructokinase, platelet type	0	0	4	4
Protein kinase C epsilon type	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 1	0	0	4	4
Angiopoietin-1 receptor	0	1	4	5
Mitogen-activated protein kinase kinase kinase 10	0	0	4	4
Protein kinase C theta type	0	0	4	4
Activin receptor type-1	0	0	4	4
Macrophage-stimulating protein receptor	0	0	4	4
Focal adhesion kinase 1	0	1	4	5
Protein kinase C zeta type	0	0	3	3
Protein kinase C delta type	0	0	4	4
Tyrosine-protein kinase BTK	0	0	4	4
Tyrosine-protein kinase receptor TYRO3	0	0	4	4
Cyclin-dependent kinase 18	0	0	4	4
Activated CDC42 kinase 1	0	0	4	4
Epithelial discoidin domain-containing receptor 1	0	2	4	6
Tyrosine-protein kinase ITK/TSK	0	0	4	4
Myotonin-protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	4	4
Tyrosine-protein kinase Mer	0	0	4	4
Serine/threonine-protein kinase 4	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	4	5
Serine/threonine-protein kinase PAK 1	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase 7	0	0	4	4
Serine/threonine-protein kinase PAK 2	0	0	4	4
Serine/threonine-protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 1	0	0	4	4
cGMP-dependent protein kinase 2	0	0	4	4
Integrin-linked protein kinase	0	0	4	4
Rho-associated protein kinase 1	0	0	4	4
Non-receptor tyrosine-protein kinase TNK1	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 1	0	1	4	5
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	4	4
Activin receptor type-2B	0	0	4	4
Bone morphogenetic protein receptor type-2	0	0	4	4
Protein-tyrosine kinase 6	0	0	4	4
cGMP-dependent protein kinase 1	0	0	4	4
Cyclin-dependent kinase 13	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	4	4
Protein-tyrosine kinase 2-beta	0	0	4	4
Maternal embryonic leucine zipper kinase	0	0	4	4
Structural maintenance of chromosomes protein 1A	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	3	3
Cyclin-dependent kinase 10	0	0	2	2
Serine/threonine-protein kinase D1	0	0	4	4
Serine/threonine-protein kinase 38	0	0	4	4
Receptor tyrosine-protein kinase erbB-4	0	1	4	5
Ribosomal protein S6 kinase alpha-2	0	0	4	4
Ephrin type-A receptor 7	0	0	4	4
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	1	4	5
Dual specificity testis-specific protein kinase 1	0	0	4	4
Myosin light chain kinase, smooth muscle	0	0	4	4
Mitogen-activated protein kinase 11	0	0	4	4
Serine/threonine-protein kinase STK11	0	0	4	4
Rhodopsin kinase GRK1	0	0	4	4
NT-3 growth factor receptor	0	0	4	4
Serine/threonine-protein kinase N1	0	0	4	4
Serine/threonine-protein kinase N2	0	0	4	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	4	4
Mitogen-activated protein kinase kinase kinase 11	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	4	4
Mitogen-activated protein kinase 6	0	0	4	4
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	4	4
Discoidin domain-containing receptor 2	0	3	4	7
AP2-associated protein kinase 1	0	1	4	5
Myosin light chain kinase 3	0	0	4	4
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 19	0	0	4	4
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	0	4	4
Rab-like protein 3	0	0	4	4
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	4	5
Serine/threonine-protein kinase MRCK alpha	0	0	4	4
Serine/threonine-protein kinase MRCK gamma	0	0	4	4
Serine/threonine-protein kinase Nek5	0	0	4	4
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	4	4
Dual serine/threonine and tyrosine protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 15	0	0	4	4
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	4	4
Serine/threonine-protein kinase MARK2	0	0	4	4
ATP-dependent RNA helicase DHX30	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	4	4
STE20-related kinase adapter protein alpha	0	0	4	4
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	4	4
Serine/threonine-protein kinase 32C	0	0	4	4
Serine/threonine-protein kinase pim-3	0	0	4	4
ATP-dependent RNA helicase DDX42	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	4	4
Myosin light chain kinase family member 4	0	0	4	4
Homeodomain-interacting protein kinase 1	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1D	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	4	4
MAP kinase-activated protein kinase 5	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	4	4
Serine/threonine-protein kinase NIM1	0	0	4	4
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	4	4
Misshapen-like kinase 1	0	0	4	4
Serine/threonine-protein kinase DCLK2	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	4	4
Casein kinase I isoform alpha-like	0	0	4	4
Homeodomain-interacting protein kinase 4	0	0	4	4
Myosin-IIIa	0	0	4	4
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	4	4
Serine/threonine-protein kinase Nek11	0	0	4	4
Atypical kinase COQ8A, mitochondrial	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	4	4
Mitogen-activated protein kinase 15	0	0	4	4
Serine/threonine-protein kinase Nek9	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	4	4
Serine/threonine-protein kinase 35	0	0	4	4
Serine/threonine-protein kinase Nek7	0	0	4	4
Rhodopsin kinase GRK7	0	0	4	4
Serine/threonine-protein kinase 32A	0	0	4	4
Myosin-IIIb	0	0	4	4
ATP-dependent RNA helicase DDX1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	4	4
Cyclin-dependent kinase-like 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	4	4
Serine/threonine-protein kinase Sgk3	0	0	4	4
Atypical kinase COQ8B, mitochondrial	0	0	4	4
Aurora kinase B	0	1	4	5
MAP/microtubule affinity-regulating kinase 4	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Serine/threonine-protein kinase Nek1	0	0	4	4
Cyclin-dependent kinase 15	0	0	4	4
PAS domain-containing serine/threonine-protein kinase	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	4	4
EKC/KEOPS complex subunit TP53RK	0	0	4	4
SRSF protein kinase 1	0	0	4	4
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 5	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	4	4
Mitogen-activated protein kinase kinase kinase 3	0	0	4	4
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO2	0	0	4	4
Cyclin-dependent kinase 19	0	0	4	4
Transient receptor potential cation channel subfamily M member 6	0	0	4	4
Testis-specific serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase 33	0	0	4	4
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	4	4
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	0	4	4
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	4	4
STE20-like serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO3	0	0	4	4
Homeodomain-interacting protein kinase 2	0	0	4	4
Tyrosine-protein kinase Srms	0	0	4	4
Homeodomain-interacting protein kinase 3	0	0	4	4
Serine/threonine-protein kinase PLK3	0	1	4	5
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	4	4
Serine/threonine-protein kinase Nek6	0	0	4	4
Casein kinase I isoform gamma-1	0	0	4	4
Serine/threonine-protein kinase PAK 6	0	1	4	5
SNF-related serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase LATS2	0	0	4	4
Serine/threonine-protein kinase 36	0	0	4	4
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
Isoleucine--tRNA ligase, mitochondrial	0	0	4	4
BMP-2-inducible protein kinase	0	0	4	4
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	4	4
Mitogen-activated protein kinase kinase kinase 20	0	0	4	4
Cyclin-dependent kinase 12	0	0	4	4
Serine/threonine-protein kinase PLK2	0	1	4	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase MARK1	0	0	4	4
Serine/threonine-protein kinase pim-2	0	0	4	4
Serine/threonine-protein kinase PAK 5	0	1	4	5
Serine/threonine-protein kinase 26	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	4	4
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	4	4
Alpha-1A adrenergic receptor	0	1	0	1
Serine/threonine-protein kinase NLK	0	0	4	4
Phosphatidylinositol 4-kinase beta	0	0	4	4
Serine/threonine-protein kinase 17A	0	0	4	4
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	4	4
Ephrin type-A receptor 6	0	0	4	4
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	4
Serine/threonine-protein kinase TBK1	0	1	4	5
Septin-9	0	0	4	4
Death-associated protein kinase 2	0	0	4	4
Ribosomal protein S6 kinase alpha-6	0	0	4	4
TRAF2 and NCK-interacting protein kinase	0	0	4	4
Serine/threonine-protein kinase tousled-like 1	0	0	4	4
Serine/threonine-protein kinase TAO2	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
ALK tyrosine kinase receptor	0	1	4	5
SRSF protein kinase 3	0	0	4	4
Serine/threonine-protein kinase ICK	0	0	4	4
Cyclin-dependent kinase 11A	0	0	4	4
Aurora kinase C	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	4	4
RAC-gamma serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase 38-like	0	0	4	4
Microtubule-associated serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase SIK3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 2	0	0	4	4
Thyroid hormone receptor-associated protein 3	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 3	0	0	4	4
Serine/threonine-protein kinase MRCK beta	0	0	4	4
Interleukin-1 receptor-associated kinase 3	0	0	4	4
Serine/threonine-protein kinase 24	0	0	4	4
Casein kinase I isoform gamma-3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 4	0	0	4	4
Cereblon isoform 4	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	3
DNA damage-binding protein 1	0	1	0	1
Protein cereblon	0	4	1	7
Zinc finger protein Aiolos	0	0	1	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
bcl-2-related protein A1	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Insulin receptor	0	3	0	3
Integrin alpha-L	0	1	1	2
Lanosterol 14-alpha demethylase	0	4	0	4
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Methionine aminopeptidase	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Calmodulin-domain protein kinase 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Chain A, Gyrase	0	0	1	1
Genome polyprotein	0	1	1	2
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90-beta	0	1	2	4
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
Cell division inhibitor SulA	0	0	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA topoisomerase	0	1	0	1
Microtubule-associated proteins 1A/1B light chain 3B	0	2	1	3
Microtubule-associated proteins 1A/1B light chain 3A	0	2	1	3
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
streptokinase A precursor	0	0	1	1
Trypsin	0	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Receptor protein-tyrosine kinase	0	1	0	1
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Dihydrofolate reductase	0	1	0	1
dopamine D1 receptor	2	0	0	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Solute carrier family 22 member 7	0	1	0	2
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	4	1	6
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Potassium channel subfamily K member 3	0	1	0	1
ATP-binding cassette sub-family C member 9	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
NS5	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	2	0	3
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
photoreceptor-specific nuclear receptor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Protein delta homolog 1	0	1	1	2
Serine/threonine-protein kinase ULK3	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Hematopoietic prostaglandin D synthase	0	2	0	2
Alpha-1A adrenergic receptor	0	1	1	2
Tryptophan 5-hydroxylase 1	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
MSH	0	0	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Cytidine Deaminase	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Equilibrative nucleoside transporter 2	0	2	0	2
Equilibrative nucleoside transporter 1	0	2	0	2
Uridine-cytidine kinase 1	0	0	0	1
Solute carrier family 28 member 3	0	2	0	2
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	0	1	0	1
Seminal ribonuclease	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	0	0	1
Ribonucleoside-diphosphate reductase subunit M2	0	0	0	1
P2Y purinoceptor 2	0	0	2	2
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
UDP-galactopyranose mutase	0	0	1	1
P2Y purinoceptor 6	0	0	2	2
P2Y purinoceptor 14	0	0	2	2
UDP-galactopyranose mutase	0	0	1	1
P2Y purinoceptor 6	0	0	1	1
Ribonucleoside-diphosphate reductase subunit M2 B	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Cytochrome P450 2E1	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Constitutional Liver Dysfunction

Synonyms(12)

Research Excerpts

Overview

Context

Treatment

Research

Studies (470)

Protein Targets (1,852)

Constitutional Liver Dysfunction

Synonyms(12)

Research Excerpts

Overview

Context

Treatment

Research

Studies (470)

Drugs Studied (203)

Protein Targets (1,852)