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retinoic acid
A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified).
ChEBI ID: 26536
Members (3)
| Member | Definition | Role |
|---|
| alitretinoin | A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry. | 9-cis-retinoic acid |
| isotretinoin | A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases. | isotretinoin |
| tretinoin | A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. | all-trans-retinoic acid |
Research
Studies (25,665)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 3,616 (14.09) | 18.7374 |
| 1990's | 7,242 (28.22) | 18.2507 |
| 2000's | 6,804 (26.51) | 29.6817 |
| 2010's | 6,115 (23.83) | 24.3611 |
| 2020's | 1,888 (7.36) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 1,636 (5.73%) | 5.53% |
| Reviews | 2,548 (8.92%) | 6.00% |
| Case Studies | 2,463 (8.62%) | 4.05% |
| Observational | 30 (0.10%) | 0.25% |
| Other | 21,895 (76.63%) | 84.16% |