Page last updated: 2024-08-05 12:04:14

beta-lactone

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ChEBI ID: 49043

Members (4)

MemberDefinitionRole
beta-butyrolactonebeta-Butyrolactone
marizomibA salinosporamide in which the core (1R)-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione skeleton is substituted at positions 1, 4, and 5 by (1S)-cyclohex-2-en-1-yl(hydroxy)methyl, 2-chloroethyl, and methyl groups, respectively (the 1R,4R,5S diastereoisomer). A potent proteasome inhibitor, it has attracted interest for potential use in the treatment of various cancers.salinosporamide A
orlistatA carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug.orlistat
vittatalactoneVittatalactone

Research

Studies (1,525)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19909 (0.59)18.7374
1990's135 (8.85)18.2507
2000's692 (45.38)29.6817
2010's533 (34.95)24.3611
2020's156 (10.23)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials278 (17.41%)5.53%
Reviews364 (22.79%)6.00%
Case Studies70 (4.38%)4.05%
Observational1 (0.06%)0.25%
Other884 (55.35%)84.16%