A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
| Excerpt | Reference |
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| "Acne vulgaris is a chronic inflammatory skin disease around pilosebaceous unit." | ( Liu, J; Liu, X; Shi, L; Wang, X; Xu, D; Yang, J; Zeng, Q; Zhang, L, 2021) |
| "Acne vulgaris is a chronic, inflammatory skin condition of pilosebaceous units." | ( Gajjar, T; Kumawat, R; Patel, N; Rajaiah Yogesh, H, 2022) |
| "Acne vulgaris is a ubiquitous condition in men and women starting in adolescence." | ( Piszczatoski, CR; Powell, J, 2021) |
| "Acne vulgaris is an inflammatory disease of the pilosebaceous unit of the skin that primarily involves the face and trunk and affects approximately 9% of the population worldwide (approximately 85% of individuals aged 12-24 years, and approximately 50% of patients aged 20-29 years)." | ( Eichenfield, DZ; Eichenfield, LF; Sprague, J, 2021) |
| "Acne vulgaris is classified based on patient age, lesion morphology (comedonal, inflammatory, mixed, nodulocystic), distribution (location on face, trunk, or both), and severity (extent, presence or absence of scarring, postinflammatory erythema, or hyperpigmentation)." | ( Eichenfield, DZ; Eichenfield, LF; Sprague, J, 2021) |
| "Acne vulgaris is a chronic inflammatory disease, which causes scar formation and changed pigmentation." | ( Daye, M; Temiz, SA, 2022) |
| "Acne vulgaris is one of the most common dermatologic complaints." | ( Al Muqarrab, F; Almohssen, A, 2022) |
| "Acne vulgaris is a common chronic inflammatory disease with a multifactorial pathogenesis." | ( Barbieri, JS; Drake, L; Mostaghimi, A; Reyes-Hadsall, S, 2022) |
| "Acne vulgaris is a chronic inflammatory skin disease around pilosebaceous unit." | ( Liu, X; Shi, L; Wang, P; Wang, X; Yan, G; Yang, J; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhou, Z, 2022) |
| "Background: Acne vulgaris is one of the most common skin diseases." | ( Adamski, Z; Bolesławska, I; Dańczak-Pazdrowska, A; Jagielski, P; Kaźmierska, A; Kosewski, G; Polańska, A; Przysławski, J, 2022) |
| "Acne vulgaris is a common dermatologic disease affecting 40 to 50 million individuals in the United States each year." | ( Brahe, C; Park, AM, 2022) |
| "Acne vulgaris is a multifactorial chronic disorder of the pilosebaceous unit." | ( Dash, G; Galadari, H; Gold, M; Goldust, M; Grabbe, S; Kroumpouzos, G; Patil, A, 2022) |
| "Acne vulgaris is a common global skin disease affecting teenagers and adults and exerting serious psychological impacts which includes everlasting scarring, reduced self-image, depression and anxiety." | ( Abdullah, -; Haroon, U; Sultana, A; Tabassum, A; Tajammul, A; Zuberi, MH, 2022) |
| "Acne vulgaris is a chronic inflammatory skin disease." | ( Chan, LP; Chen, CW; Chen, JF; Ho, HH; Huang, YF; Kuo, YW; Liang, CH; Lin, JH; Tsai, SY; Yi, TH, 2022) |
| "Acne vulgaris is a common skin condition that affects adolescents and young adults." | ( Badaruddin, NSF; Bujang, MA; Foo, SY; Lim, TH; Muniandy, P, 2022) |
| "Acne vulgaris is a common skin disease affecting 80-90% of teenagers worldwide." | ( Arya, H; Gautam, HK; Kumar, P; Singh, AP; Singh, V, 2022) |
| "Acne vulgaris is one of the most common dermatological diseases." | ( Chen, F; Gao, L; Huang, X; Jiang, L; Lao, Y; Li, N; Lu, J; Lv, L; Yan, W; Yang, F; Yi, L; Zhang, B, 2023) |
| "Acne vulgaris is caused by dyslipidemia, dyskeratosis and/or abnormal bacterial growth." | ( Hosokawa, M; Kajiyama, A; Kiyozuka, A; Miyaki, M; Ootsuki, R; Takagi, Y, 2023) |
| "Acne vulgaris is a common skin condition that may cause psychosocial distress." | ( Berg, L; Bromham, N; Daly, CH; Dworzynski, K; Healy, E; Mavranezouli, I; Ravenscroft, JC; Welton, NJ; Wilcock, J; Wood, D; Xu, J, 2022) |
| "Acne vulgaris is typically treated with a combination of a topical retinoid plus an antimicrobial agent, as recommended by national and international evidence-based guidelines around the globe." | ( Chavda, R; Dréno, B; Layton, AM; Rocha, M; Troielli, P, 2022) |
| "Acne vulgaris is a common skin disease caused by multifactorial reasons involving excessive sebum secretion and inflammation by Cutibacterium acnes (C." | ( Bang, J; Han, S; Kim, BR; Kim, S; Lee, YD; Shin, JW; Yang, JK, 2023) |
| "Acne vulgaris is the eighth most common disease worldwide and presents with inflammatory and noninflammatory skin lesions along with other dermal abnormalities." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Acne vulgaris is the eighth most common disease worldwide and presents with inflammatory and noninflammatory skin lesions along with other dermal abnormalities." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Acne vulgaris is a troubling skin disease known to have both physiologic and psychological effects on patients." | ( Alajmi, A; Alazemi, M; Jfri, A; Ladha, MA, 2022) |
| "Acne vulgaris is the eighth most common disease worldwide and presents with inflammatory and noninflammatory skin lesions along with other dermal abnormalities." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Acne vulgaris is a troubling skin disease known to have both physiologic and psychological effects on patients." | ( Alajmi, A; Alazemi, M; Jfri, A; Ladha, MA, 2022) |
| "Acne vulgaris is a common chronic inflammatory skin disease, which is considered one of the diseases of civilization due to the significant influence of environmental factors on the severity and frequency of these lesions." | ( Borzyszkowska, D; Brodowska, A; Cymbaluk-Płoska, A; Kozłowski, M; Malczyk-Matysiak, K; Niedzielska, M; Przepiera, A; Sowińska-Przepiera, E, 2022) |
| "Severe acne vulgaris is a common chronic inflammatory skin disease worldwide." | ( Liu, P; Liu, X; Wang, P; Wang, X; Wu, Y; Xu, D; Yan, G; Zeng, Q; Zhang, G; Zhang, H; Zhang, L, 2023) |
| "Acne vulgaris is associated with insulin resistance and elevated insulin-like growth factor-1 (IGF-1)." | ( De, D; Dutta, P; Handa, S; Kamboj, P; Kaushik, A; Pal, A; Saikia, UN, 2023) |
| "Acne vulgaris is a common chronic inflammatory disorder of the pilosebaceous unit." | ( Abd-Rabboh, MMA; Hussein, TM; Taha, AAA; Tawfik, NTA, 2023) |
| "Acne vulgaris is a common skin disease that is more common in young population and it can be associated with some sequels after resolving the lesions." | ( Abouie, A; Bazargan, AS; Gheisari, M; Mirahmadi, S; Taheri, A; Ziaeifar, E, 2023) |
| "Acne vulgaris is the most common skin condition in the US, affecting up to 50 million Americans." | ( Baldwin, H; Draelos, Z; Farberg, A; Frey, C; Hartman, C; Lain, E; Meltzer, R, 2023) |
| "Acne vulgaris is a very prevalent dermatological condition, especially among adolescents and young adults up to 25 years old, classifying it as juvenile acne." | ( Fernandes, T; Magina, S, 2023) |
| "Acne vulgaris is challenging to treat for several individuals." | ( Ahmed, NA; Hamdino, M; Hammoda, TM, 2023) |
| "Acne vulgaris is a chronic inflammatory disease that frequently occurs in adolescence." | ( Bennardo, L; Cannarozzo, G; Chester, J; Del Duca, E; Farnetani, F; Manfredini, M; Nisticò, SP; Pellacani, G; Petrini, N; Sannino, M; Schipani, G; Tamburi, F, 2021) |
| "Acne vulgaris is a common disease which affects about 85% of the population." | ( Janani, SK; Karthika, C; Sureshkumar, R; Upadhyayula, SSN; Vasanthi, C, 2019) |
| "Acne vulgaris is the most prevalent chronic skin disease in the United States, affecting nearly 50 million people per year, mostly adolescents and young adults." | ( Broussard, A; Marshall, MD; Oge', LK, 2019) |
| "Acne vulgaris is a chronic disfiguring inflammatory disease of adolescents and adults affecting up to 90% of the population around the world." | ( Abdelmaksoud, A; Galadari, H; Goldust, M; Grabbe, S; Gupta, M; Karagaiah, P; Kassir, M; Katsambas, A; Lotti, T; Sonthalia, S; Wollina, U, 2020) |
| "Acne vulgaris is the most common skin disease treated by dermatologists." | ( Landis, MN, 2020) |
| "Acne vulgaris is an extraordinarily common skin condition in adolescents." | ( Cohen, BA; Habeshian, KA, 2020) |
| "Acne vulgaris is a chronic inflammatory disease of the sebaceous glands that occurs in adolescent men and women." | ( Kou, L; Ren, J; Tao, Y; Yang, B; Yu, N, 2020) |
| "Acne vulgaris is a chronic inflammatory skin disease that mostly develops during adolescence and continues throughout adulthood." | ( Akyol, M; Guner, RY; Kozan, A, 2020) |
| "Acne vulgaris is a common skin disease in adolescents known to be associated with oxidative stress." | ( Abusoglu, S; Akyurek, F; Ataseven, A; Kurku, H; Saylam Kurtipek, G; Tunçez Akyürek, F; Unlu, A, 2020) |
| "Acne vulgaris is a common inflammatory skin disease that affects the pilosebaceous glands." | ( El-Halaby, AR; Gheida, SF; Hassan, GFR; Ibrahim, ZA; Mohammed, DA, 2022) |
| "Acne vulgaris is a chronic inflammatory disease affecting the pilosebaceous unit." | ( Atilla, S; Ozdemir, S; Pancar, GS; Sarac, N, 2022) |
| "Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions." | ( Annunziata, MC; Cinelli, E; Donnarumma, M; Fabbrocini, G; Milani, M; Villani, A, 2020) |
| "Acne vulgaris is a chronic inflammatory disease affecting the pilosebaceous unit." | ( Karaosmanoğlu, N; Mülkoğlu, C, 2020) |
| "Acne vulgaris is a chronic, inflammatory, skin condition that involves the pilosebaceous follicles and is influenced by a variety of factors including genetics, androgen-stimulation of sebaceous glands with abnormal keratinization, colonization with Cutibacterium acnes (previously called Propionibacterium acnes), and pathological immune response to inflammation." | ( Azmeh, R; Cabral, MD; Dickson, CA; Greydanus, DE; Patel, DR, 2021) |
| "Acne vulgaris is one of the most common dermatologic disorders affects people of all races and ethnicities and has many adverse effects on the quality of life." | ( Goodarzi, A; Mardani, N; Mozafarpoor, S; Nikkhah, F, 2021) |
| "Acne vulgaris is a chronic inflammatory skin disease." | ( Jaturapisanukul, K; Kamanamool, N; Kanokrungsee, S; Puttarak, P; Rachpirom, M; Rojhirunsakool, S; Udompataikul, M, 2021) |
| "Acne vulgaris is the most common dermatological disorder worldwide, causing significant physical and psychological morbidity." | ( Aschoff, R; Haase, R; Kuske, M; Möller, S, 2021) |
| "Acne vulgaris is a common skin disease that manifests clinically as comedones, papules, nodules, and cysts." | ( Brownell, L; E, Y; Geen, S; Lee, WL, 2021) |
| "Acne vulgaris is a common condition." | ( Chen, L; Chen, Q; Li, W; Tang, J; Wang, C; Yang, J; Zhang, C; Zhang, S; Zhang, X, 2021) |
| "Acne vulgaris is a chronic inflammatory cutaneous disease." | ( Liu, J; Liu, X; Shi, L; Wang, X; Xu, D; Yang, J; Zeng, Q; Zhang, L, 2021) |
| "Acne vulgaris is the most common skin condition worldwide, and it is associated with substantial psychological comorbidity." | ( Emmerich, VK; Feldman, SR; Purvis, CG, 2021) |
| "Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit." | ( Douglas, SC; Hall, JM; Rao, A, 2021) |
| "Acne vulgaris is a common skin condition affecting the pilosebaceous unit of the skin characterized by the presence of comedones, papules, pustules, nodules, and cysts, which might result in permanent scars." | ( Calvisi, L, 2021) |
| "Acne vulgaris is a prevalent skin disease lacking effective and well-tolerated treatment." | ( Cao, K; Chen, G; Hou, X; Hu, T; Ju, Q; Li, X; Mo, X; Pan, Z; Wang, L; Wei, Z; Wu, Q; Ye, F; Zouboulis, CC, 2021) |
| "Acne vulgaris is a global disease with increasing prevalence in adolescents." | ( Nguyen, HL; Tollefson, MM, 2017) |
| "Acne vulgaris is a disease of pilosebaceous units with multifactorial pathogenesis, including hyperkeratinization, increased sebum secretion, and inflammation." | ( Flach, CR; Li, WH; Mendelsohn, R; Parsa, R; Southall, MD; Zhang, Q, 2017) |
| "Acne vulgaris is a common cosmetic problem that is frequently associated with psychosocial disturbances as well as increased oxidative stress." | ( Awad, SM; Ezzat, GM; Mohamed, NA; Morsy, H; Noaman, MM; Sayed, AA, 2018) |
| "Acne vulgaris is a multifactorial disorder which is ideally treated with combination therapy with topical retinoids and antibiotics." | ( Ashique Rahman, MA; Hota, D; Maiti, R; Parida, S; Sirka, CS; Srinivasan, A, 2017) |
| "Acne vulgaris is a common skin defect, usually occurring during adolescence, but often it can persist in adults leaving permanent face scarring." | ( Bassino, E; Gasparri, F; Munaron, L, 2018) |
| "Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages." | ( Cervantes, J; Eber, AE; Keri, JE; Nascimento, VM; Nouri, K; Perper, M, 2018) |
| "Acne vulgaris is a prevalent skin disorder impairing both physical and psychosocial health." | ( Li, C; Liu, P; Xu, X; Zhang, X; Zhao, Z; Zheng, Y, 2017) |
| "Acne vulgaris is a common inflammatory skin disease." | ( Aly, SS; El Taieb, MA; El-Hamd, MA; Ibrahim, HM, 2019) |
| "Acne vulgaris is a chronic inflammatory skin disease that manifests as open and closed comedones as well as inflammatory papules, pustules, and nodules localized on face and trunk." | ( Bianchi, L; Cannizzaro, MV; Dattola, A; Del Duca, E; Garofalo, V, 2018) |
| "Acne vulgaris is one of the most common dermatological problems, and its therapeutic options include topical and systemic retinoids and antibiotics." | ( Choi, SH; Kim, KH; Seo, JW, 2018) |
| "Acne vulgaris is a chronic inflammatory skin disease, commonly treated with topical or systemic drugs, according to the severity of the condition." | ( Bianchi, L; Campione, E; Cannizzaro, MV; Dattola, A; Del Duca, E; Garofalo, V; Milani, M; Serini, SM; Ventura, A, 2019) |
| "Acne vulgaris is a common dermatologic disorder which results in psychological consequences." | ( Ahmadvand, A; Mahjub, R; Mehrpooya, M; Mohammadi, Y; Yasrebifar, F; Yazdanfar, A, 2018) |
| "Acne vulgaris is a common inflammatory skin condition which is treated using Tretinoin (TRE), a widely used retinoid." | ( Ahmad Nasrollahi, S; Dinarvand, R; Farboud, ES; Firooz, A; Hassanzadeh, H; Mirrahimi, B; Nassiri Kashani, M; Sabouri, M; Samadi, A, 2018) |
| "Introduction: Acne vulgaris is more common in females than males and is challenging to treat." | ( Alvandi, N; Bai, Z; Baldwin, H; Harper, J; Kircik, L; Tanghetti, E, 2018) |
| "Introduction: Acne vulgaris is more common in females than males and is challenging to treat." | ( Alvandi, N; Bai, Z; Baldwin, H; Harper, J; Kircik, L; Tanghetti, E, 2018) |
| "Introduction: Acne vulgaris is more common in females than males and is challenging to treat." | ( Alvandi, N; Bai, Z; Baldwin, H; Harper, J; Kircik, L; Tanghetti, E, 2018) |
| "Acne vulgaris is a prevalent cutaneous disease characterized by a multifactorial pathogenic process including hyperseborrhea, inflammation, over-keratinization of follicular keratinocytes and Propionibacterium acnes (P acnes) overgrowth." | ( Cong, T; Du, D; He, G; Jiang, X; Li, X; Lu, J; Wen, X, 2019) |
| "Acne vulgaris is one of the most common chronic diseases worldwide with the high prevalence ratio of about 80-85% in patients who are in puberty period." | ( Aslan, M; Çalamak, S; Eroğlu, İ; Gultekinoglu, M; Kart, D; Ulubayram, K; Yaman, Ü, 2020) |
| "Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit." | ( Akin Belli, A; Alatas, ET; Dogan, G; Kalayci, M; Kara Polat, A, 2019) |
| "Acne vulgaris is one of the most common skin disorders." | ( Hasibur, MR; Meraj, Z, 2013) |
| "Acne vulgaris is a chronic inflammatory disease that usually requires systemic treatment for severe forms." | ( Boyraz, N; Mustak, PK, 2013) |
| "Moderate to severe acne vulgaris is often treated with a combination of an oral antibiotic, topical antibiotic/retinoid, and benzoyl peroxide (BP), but data are limited on the efficacy of this and other combination regimens that incorporate both oral and topical therapies." | ( Del Rosso, J; Dover, JS; Draelos, Z; Gold, M; Lin, X; Shamban, A; Stein, L; Swinyer, L; Thiboutot, D; Webster, G; Zaenglein, AL, 2013) |
| "Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting Propionibacterium acnes has a significant role in its pathogenesis." | ( Agak, GW; Elashoff, D; Garbán, HJ; Kim, J; Kim, MH; Krutzik, SR; Nobe, J; Qin, M; Tristan, GR, 2014) |
| "Acne vulgaris is a common condition in adolescence and also for many women of childbearing age." | ( Meredith, FM; Ormerod, AD, 2013) |
| "Acne vulgaris is a commonly seen dermatologic condition that plagues millions and can be very psychosocially disabling." | ( English, JC; Prevost, N, 2013) |
| "Acne vulgaris is a chronic skin disorder leading to inflammation as a result of the production of reactive oxygen species due to the active involvement of Propionibacterium acnes (P." | ( Hussein, A; Kishore, N; Lall, N; Sharma, R, 2013) |
| "Acne vulgaris is a pervasive inflammatory disorder of the skin, with multiple etiologies and treatment options." | ( Keck, L; Shariff, A; Zlotoff, B, 2014) |
| "Acne vulgaris is a common skin disease in which abnormal desquamation, excess sebum production, proliferation of Propionibacterium acnes, and production of proinflammatory mediators all contribute to the pathogenesis of the disease." | ( Harvey, A; Huynh, TT, 2014) |
| "Acne vulgaris is the most common skin disease, causing significant psychosocial problems such as anxiety and depression similar to a chronic illness for those afflicted." | ( Debbab, A; Eger, A; Genov, M; Hollaus, R; Hundsberger, H; Kreiseder, B; Nagl, M; Pretsch, A; Pretsch, D; Proksch, P; Schwendinger, K; Wiederstein, M; Wiesner, C; Zinssmeister, D, 2014) |
| "Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults." | ( Maleki, N; Rostami Mogaddam, M; Safavi Ardabili, N; Soflaee, M, 2014) |
| "Acne vulgaris is a disorder of the pilosebaceous unit of the skin, and the underlying mechanism is still obscure." | ( Furukawa, F; Kaminaka, C; Kanazawa, N; Kuramoto, T; Yamamoto, Y; Yoshimasu, T, 2014) |
| "Acne vulgaris is the most common disease of the adolescence age (70-94%)." | ( Capizzi, R; De Waure, C; Fossati, B; Frascione, P; Guerriero, C; Masini, F; Ricci, F, 2014) |
| "Acne vulgaris is a common chronic disease, and evidence-based clinical practice guidelines (CPGs) can provide credible treatment information." | ( Fernando, D; Kawala, C; Tan, JK, 2014) |
| "Acne vulgaris is a common condition which remains challenging to treat in some cases." | ( Al-Niaimi, F; Momen, S, 2015) |
| "Acne vulgaris is a nearly universal cutaneous disease characterized by multifactorial pathogenic processes." | ( Kim, YI; Kwon, HH; Lee, YS; Min, S; Park, JY; Park, SY; Suh, DH; Thiboutot, DM; Yoon, JY, 2015) |
| "Acne vulgaris is one of the most common skin diseases in adolescents." | ( Liu, Y; Ma, Y; Ren, J; Wang, Q; Xiang, L, 2015) |
| "Acne vulgaris is a chronic inflammatory disease involving the pilosebaceous unit of the skin." | ( Alkan, S; Kalem, A; Kayiran, N; Kilinc, EO; Kimyon, G; Kirtak, N; Kisacik, B; Onat, AM; Pehlivan, Y; Zengin, O, 2015) |
| "Acne vulgaris is one of the most common diseases of the youth." | ( Aksoy, H; Aydin, T; Borlu, M; Cinar, E; Çinar, L; Ergin, C; Karadag, MA; Kartal, D, 2016) |
| "Acne vulgaris is a common condition that occurs in all skin types." | ( Agbai, ON; Al-Jamal, M; Chaffins, M; Devpura, S; Hamzavi, IH; Isedeh, P; Kohli, I; Lim, HW; Mahan, M; Matsui, MS; Vanderover, G, 2016) |
| "Acne vulgaris is a disease of the sebaceous follicle which affects up to 90% of adolescent patients." | ( Capizzi, R; De Waure, C; Fossati, B; Frascione, P; Guerriero, C; Masini, F; Ricci, F, 2016) |
| "Acne vulgaris is a common, chronic skin disease that requires long-term therapy." | ( Kircik, LH, 2016) |
| "Acne vulgaris is a widely prevalent chronic skin disease." | ( Hassoun, LA; Ornelas, JN; Sivamani, RK, 2016) |
| "Acne vulgaris is a puberty-onset chronic inflammatory disease of the pilosebaceous unit." | ( Kükner, Ş; Polat, M, 2017) |
| "Mild-to-moderate acne vulgaris is treated with a range of mono- and combination therapies; however, clinical evidence is still required to optimize treatment recommendations." | ( Hennig, M; Ress, C; Schaller, M; Sebastian, M; Seidel, D, 2016) |
| "Acne vulgaris is an extremely common skin condition." | ( Ibrahim, SM; Moftah, NH; Wahba, NH, 2016) |
| "Acne vulgaris is one of the most common diseases of the youth." | ( Aksoy, H; Aydin, T; Borlu, M; Cinar, E; Cinar, SL; Ferahbas, A; İmamoğlu, H; Kartal, D; Öz, L, 2017) |
| "Acne vulgaris is a chronic inflammatory disease characterized by non-inflammatory and inflammatory lesions that can cause scarring." | ( Bagatin, E; Gonçalves, RG; Guadanhim, LR, 2016) |
| "Acne vulgaris is a multifactorial skin disease associated with the colonization of Propionibacterium acnes." | ( Ghosh, S; Gupta, T; Kaur, SP; Sadhasivam, S; Saini, S; Sardana, K; Sengupta, S; Sinha, M, 2016) |
| "Acne vulgaris is a common and distressing condition that typically presents in adolescents and young adults." | ( Ditre, CM; Rattanaumpawan, P; Tangjaturonrusamee, C, 2016) |
| "Acne vulgaris is a very common skin disorder affecting human beings." | ( Amah, HC; Anyanwu, CJ; Ikaraoha, CI; Mbadiwe, NC; Nwadike, CN; Odekhian, J, 2017) |
| "Acne vulgaris is a chronic inflammatory disease affecting the pilosebaceous unit in the skin." | ( Aksu Arıca, D; Bahadır, S; Baykal Şahin, H; Baykal Selçuk, L; Yaylı, S, 2017) |
| "Acne vulgaris is a common skin problem affecting nearly 90% of adolescents and its development is associated with a colonization of Propionibacterium acnes (P." | ( Im, BN; Jeong, S; Kim, MK; Lee, J; Na, K; Park, H; Yang, SG, 2016) |
| "Acne vulgaris is a very common chronic inflammatory disorder, yet its pathogenesis is not clearly understood." | ( Askari, N; Faghihzadeh, S; Ghazanfari, T; Khodashenas, Z; Mohammad Hassan, Z; Shams, J; Soroush, MR; Vaez Mahdavi, MR; Yaraee, R, 2017) |
| "Acne vulgaris is one of the commonest dermatological diseases and its pathogenesis is multifactorial." | ( Abdel Fattah, NS; Ebrahim, AA; El Okda, ES; Shaheen, MA, 2008) |
| "Acne vulgaris is a common disorder that affects more than 17 million individuals in the United States." | ( Friedlander, SF; Tom, WL, 2008) |
| "Acne vulgaris is a common skin condition, one that is associated with significant psychological disability." | ( Kim, K; Logan, AC; Rubin, MG, 2008) |
| "Acne vulgaris is a widely prevalent skin disorder primarily treated with retinoids, which have been shown to cause skin irritation." | ( Cargill, DI; Quiring, J; Slade, HB; Vogelson, CT; Webster, G, 2009) |
| "Acne vulgaris is a multifactorial inflammatory disease of the sebaceous follicles of the face and torso that frequently occurs in adolescence." | ( Gabazza, EC; Kakeda, M; Kitagawa, H; Kurokawa, I; Mizutani, H; Sugisaki, H; Tanaka, K; Watanabe, K; Yamanaka, K, 2009) |
| "Acne vulgaris is a disease of the pilosebaceous unit characterized by the development of inflammatory and/or non-inflammatory lesions that may progress to scars." | ( Leheta, TM, 2009) |
| "Acne vulgaris is a multifactorial disease affecting a majority of the adolescent population." | ( Abulnaja, KO, 2009) |
| "Acne vulgaris is a chronic inflammatory disorder of the sebaceous follicles." | ( Batteux, F; Chéreau, C; Dupin, N; Grange, PA; Nicco, C; Raingeaud, J; Weill, B, 2009) |
| "Acne vulgaris is a common skin disorder that affects most individuals at some point in their lives." | ( Burkhart, CN; James, KA; Morrell, DS, 2009) |
| "Acne vulgaris is a multifactorial inflammatory skin disease." | ( Marcinkiewicz, J, 2009) |
| "Acne vulgaris is one of the common dermatological diseases and its pathogenesis is multifactorial." | ( Altinyazar, C; Armutcu, F; Cinar, S; Koca, R; Sarici, G; Tekin, NS, 2010) |
| "Acne vulgaris is a common problem, particularly among adolescents, which is usually resistant to monotherapy." | ( Ajami, M; Babakoohi, S; Firooz, A; Habibey, R; Nassiri-Kashani, M; Pazoki-Toroudi, H; Rahshenas, M; Shizarpour, M; Tabatabaie, H, 2010) |
| "Acne vulgaris is the most common skin disease and can pose a substantial therapeutic challenge." | ( Karsai, S; Raulin, C; Schmitt, L, 2010) |
| "Acne vulgaris is the most common dermatologic disorder in the United States." | ( Gold, LS, 2010) |
| "Acne vulgaris is a multifactorial disease of the pilosebaceous unit, resulting from abnormalities in sebum production, follicular epithelial desquamation, bacterial proliferation and inflammation." | ( Friedman, A; Kircik, L, 2010) |
| "Acne vulgaris is a common chronic skin disease affecting roughly 15 percent of the general population and up to 85 percent of adolescents and young adults." | ( Eichenfield, LF; Graeber, M; Hwa, J; Jarratt, M; Kempers, S; Liu, Y; Manna, V; Schlessinger, J, 2010) |
| "Acne vulgaris is the most common dermatological disorder in adolescence and young adults." | ( Babaeinejad, S; Fouladi, RF; Khodaeiani, E, 2011) |
| "The pathogenesis of acne vulgaris is multifactorial and entails the interplay of hormonal, microbial and immunological events." | ( El-Akhras, MA; Fathy, A; Ismael, NA; Mohamed, RW, 2009) |
| "Acne vulgaris is a common disease in adolescents, and early treatment may minimize its physical and psychological effects." | ( Dirschka, T; Eichenfield, LE; Graeber, M; Jorizzo, JL; Kerrouche, N; Lynde, C; Taub, AF, 2010) |
| "Acne vulgaris is a complex, chronic, and common skin disorder of pilosebaceous units." | ( Ayala, F; Battimiello, V; De Rosa, G; De Vita, V; Fabbrocini, G; Fardella, N; Ilardi, G; La Rotonda, MI; Longobardi, A; Mazzella, M; Pastore, F; Siano, M; Staibano, S; Vecchione, ML, 2011) |
| "Acne vulgaris is a disorder of the pilosebaceous unit in which the androgens contribute to its onset and persistence." | ( Celasco, G; Moro, L; Naumescu, E; Tiplica, GS; Trifu, V; Zalupca, L, 2011) |
| "Acne vulgaris is a chronic and frequently recurring disease." | ( Bucko, A; Dhuin, JC; Fowler, J; Jarratt, M; Kempers, S; Kerrouche, N; Kunynetz, R; Poulin, Y; Sanchez, NP, 2011) |
| "Acne vulgaris is a skin disease affecting pilosebaceous glands in which Propionibacterium acnes (P." | ( Ariès, MF; Castex-Rizzi, N; Dréno, B; Isard, O; Khammari, A; Knol, AC; Lévêque, M; Nguyen, JM, 2011) |
| "Acne vulgaris is common in young adolescents." | ( Lucky, AW; Sugarman, J, 2011) |
| "Acne vulgaris is a very common inflammatory skin disease originating from the pilosebaceous unit." | ( Mempel, M; Schnopp, C, 2011) |
| "Acne vulgaris is common throughout the world and often perceived by both patients and clinicians as an inconsequential disease of adolescence." | ( Abad-Casintahan, F; Chow, SKW; Goh, CL; Kang, S; Kubba, R; Miyachi, Y; Noppakun, N; See, J; Suh, DH; Yang, LC, 2011) |
| "Acne vulgaris is a common dermatological disorder." | ( Ding, HL; Huang, Z; Wang, HW; Wang, XL, 2011) |
| "Acne vulgaris is a common skin disease with a large quality of life impact, characterized by comedones, inflammatory lesions, secondary dyspigmentation, and scarring." | ( Hillebrand, GG; Kimball, AB; Maglione, J; Miyamoto, K; Perkins, AC, 2012) |
| "The pathogenesis of acne vulgaris is multifactorial involving infection of the pilosebaceous unit with Propionibacterium acnes and a cytokine-mediated inflammatory response." | ( Conlon, JM; Lukic, M; Popovic, S; Urbán, E, 2012) |
| "Acne vulgaris is characteristic of excess sebum production and the induction of inflammatory reactions, for example, the augmentation of cytokine, prostaglandin (PG) and matrix metalloproteinase (MMP) production in sebaceous glands and pilosebaceous units." | ( Ito, A; Noguchi, N; Sasatsu, M; Sato, T; Shirane, T, 2012) |
| "Acne vulgaris is the one of the most common skin diseases." | ( Akkaya, VB; Erturan, İ; Naziroğlu, M, 2012) |
| "Acne vulgaris is the most common disease of the pilosebaceous unit." | ( Choi, DK; Hwang, YL; Im, M; Kim, CD; Kim, SY; Lee, JH; Lee, Y; Seo, YJ; Sohn, KC; Zouboulis, CC, 2012) |
| "Acne vulgaris is a common reason why adult women present to dermatologists and can be a clinical challenge to treat." | ( Kamangar, F; Shinkai, K, 2012) |
| "Acne vulgaris is one of the most commonly seen diseases among the youth." | ( Joy, JM; Rasheed, A; Reddy, BS; Roja, C; Shama, SN, 2012) |
| "Acne vulgaris is a highly prevalent skin disorder characterized by hyperseborrhea, inflammation, and Propionibacterium acnes overgrowth." | ( Kwon, HH; Min, SU; Suh, DH; Thiboutot, DM; Yoon, JY, 2013) |
| "Acne vulgaris is one of the most common skin disorders, and oral isotretinoin has widely been used as a treatment for severe and resistant cases in recent years." | ( Javanbakht, AM; Pour, HM; Tarrahic, MJ, 2012) |
| "Acne vulgaris is one of the most common dermatological diseases, and its pathogenesis is multifactorial." | ( Ergul, KB; Filiz, A; Neslihan, D; Perihan, O, 2012) |
| "Acne vulgaris is a multifactorial skin disorder of unknown etiology." | ( Al Robaee, AA; Al-Shobaili, HA; Alzolibani, AA; Meki, AR; Rasheed, Z, 2013) |
| "Acne vulgaris is a common dermatologic disease that most frequently affects adolescents and young adults." | ( Green, L; Gwazdauskas, J; Kircik, LH, 2013) |
| "Acne vulgaris is the most common dermatologic disorder seen in American black patients (ie, African Americans and African Caribbeans, Fitzgerald skin types IV through VI)." | ( Czernielewski, J; Mizzi, F; Poncet, M, 2002) |
| "Acne vulgaris is a very common disorder, affecting virtually every adolescent at some point in time." | ( Tan, HH, 2003) |
| "Acne vulgaris is a common skin disease affecting all ages." | ( Swanson, JK, 2003) |
| "Acne vulgaris is a common skin disorder among children and young adults that carries enormous financial and psychosocial impact." | ( Smolinski, KN; Yan, AC, 2004) |
| "Acne vulgaris is a chronic inflammatory disease involving colonization of Propionibacterium acnes (P." | ( Kikuchi, M; Kitagaki, H; Kitazawa, T; Kuwahara, K; Tsukamoto, T, 2005) |
| "Acne vulgaris is a common inflammatory disorder of the skin." | ( Aytug, A; Kus, S; Yucelten, D, 2005) |
| Excerpt | Reference |
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| "Retinoids are first-line therapy in the treatment of acne vulgaris." | ( Feldman, SR; Mohney, LA; Singh, R, 2022) |
| "Various treatments for acne vulgaris exist, but little is known about their comparative effectiveness in relation to acne severity." | ( Arnold, S; Berg, L; Bromham, N; Daly, CH; Deshpande, S; Dworzynski, K; Fou, L; Healy, E; Mavranezouli, I; Phillippo, DM; Rafiq, M; Ravenscroft, JC; Welton, NJ; Wilcock, J; Wood, D; Xu, J, 2022) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Oral vitamin A is efficacious for the treatment of acne vulgaris, although the available studies have limited controls and outcomes." | ( Cook, MK; Feldman, SR; Perche, PO, 2022) |
| "Existing treatments of acne vulgaris may be complicated or elicit undesirable side effects." | ( Kim, JY; Lee, HJ; Lee, WJ; Park, KD, 2020) |
| "Isotretinoin is widely used in the treatment of acne vulgaris for more than 30 years (1)." | ( Alataş, ET; Alataş, ÖD, 2020) |
| "The first-line treatments for acne vulgaris are topical and oral medications, mainly antibiotics and retinoids." | ( Artzi, O; Friedman, O; Hilerowicz, Y; Koren, A; Mehrabi, JN; Salameh, F; Ziv, R; Zur, E, 2020) |
| "Chemical peels have been used for treatment of acne vulgaris with inadequate clinical evidence." | ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "Adapalene is used for treatment of acne vulgaris, a common dermatological disease." | ( Amani, A; Ehsani, A; Eslami Farsani, V; Jafarzadeh Kohneloo, A; Mehdizade Rayeni, N; Moghimi, HR; Najafi-Taher, R, 2022) |
| "The ongoing search for effective treatment of Acne vulgaris is concentrated, i." | ( Dryś, A; Golonka, I; Greber, KE; Junka, A; Musiał, W; Oleksy-Wawrzyniak, M; Paleczny, J; Sawicki, W, 2021) |
| "Isotretinoin is used in the treatment of severe acne vulgaris (AV), but has controversially been associated with depression and suicide." | ( Frittelli, V; Gunnarsson, R; Rea, S; Tucker, S, 2018) |
| "Isotretinoin has revolutionized the treatment of severe acne vulgaris, a condition which if left untreated may result in significant socio-psychological implications for those affected." | ( Driscoll, T; Kovitwanichkanont, T, 2018) |
| "The Guidelines for the Treatment of Acne Vulgaris of the Japanese Dermatological Association was first published in Japanese in 2008 and revised in 2016 and 2017." | ( Akamatsu, H; Furukawa, F; Furumura, M; Hayashi, N; Iwatsuki, K; Kaminaka, C; Kawashima, M; Kobayashi, M; Kono, T; Kurokawa, I; Miyachi, Y; Shimada-Omori, R; Tanioka, M; Yamamoto, Y; Yamasaki, K; Yamasaki, O, 2018) |
| "Oral antibiotics are well established treatments for acne vulgaris but are associated with undesirable side effects." | ( Bonati, LM; Dover, JS, 2019) |
| "The success rates of conventional treatments to acne vulgaris are limited because of intolerance and resistance." | ( Mei, X; Piao, Y; Shi, W, 2013) |
| "Despite many advances in the treatments of acne vulgaris the best option is still controversial as the pathogenesis of acne is rather complex, necessitating various combination therapies." | ( El-Latif, AA; Elsaie, ML; Elshahed, AR; Hassan, FA; Mohamed, AG, 2014) |
| "Topical tretinoin has been a standard treatment for acne vulgaris for more than 4 decades." | ( Kircik, LH, 2014) |
| "The biggest hurdle in the treatment of acne vulgaris is patient non-compliance that is due in large part to poor tolerability to common acne medications." | ( Bhatia, AC; Jimenez, F, 2014) |
| "Main topical treatments for acne vulgaris are retinoids, benzoyl peroxide and antibiotics in mono or combination therapy." | ( Capizzi, R; De Waure, C; Fossati, B; Frascione, P; Guerriero, C; Masini, F; Ricci, F, 2014) |
| "The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed." | ( Rolfe, HM, 2014) |
| "Topical dapsone gel, 5% is approved for treatment of acne vulgaris but has not been studied specifically in women with skin of color (SOC; Fitzpatrick skin types IV, V, or VI)." | ( Alexis, AF; Burgess, C; Callender, VD; Gallagher, CJ; Herzog, JL; Roberts, WE; Schweiger, ES; Stockton, TC, 2016) |
| "It is a very effective agent in a treatment of acne vulgaris; however, multiple side effects related to therapy with retinoids preclude the use of isotretinoin in less severe acne vulgaris." | ( Bergler-Czop, B; Brzezińska-Wcisło, L; Miziołek, B; Stańkowska, A, 2017) |
| "The current options for the treatment of acne vulgaris present many mechanisms of action." | ( Azulay-Abulafia, L; Castro, LC; Costa, Ad; Follador, I; Mulinari-Brenner, F; Sittart, JA, 2015) |
| "New topical treatments for acne vulgaris are needed for patients who have tolerance problems with current treatments." | ( Bissonnette, R; Bolduc, C; Maari, C; Nigen, S; Provost, N; Rougier, A; Seité, S, 2009) |
| "The potential of oral dapsone to treat acne vulgaris is well established, but the risks of serious side effects have made it an undesirable drug for use in the relatively healthy acne population." | ( Pickert, A; Raimer, S, 2009) |
| "Combination therapy for the topical treatment of acne vulgaris using benzoyl peroxide (BPO) and an antibiotic is more efficacious and better tolerated than treatment with either component alone." | ( Dhawan, SS, 2009) |
| "Isotretinoin is an effective treatment for acne vulgaris." | ( Akin, KO; Ertugrul, DT; Karadag, AS; Tutal, E, 2010) |
| "An alternative approach in the treatment of acne vulgaris is photodynamic therapy (PDT) that uses light and aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) production to eradicate Propionibacterium acnes found in acne lesions." | ( Barolet, D; Boucher, A, 2010) |
| "The first-line treatments for acne vulgaris are conventional topical and/or oral medications." | ( Anderson, RR; Lopes, JD; Sakamoto, FH, 2010) |
| "Topical treatment of acne vulgaris on the back is challenging largely due to the extensive broad surface with difficult to reach areas." | ( Leyden, JJ, 2010) |
| "Whereas the standard approach to the treatment of acne vulgaris has involved both systemic and topical antibiotics and topical agents such as benzoyl peroxide, problems exist due to side effects, drug resistance and lack of compliance." | ( Flint, C; Smalley, H; Wainwright, M, 2011) |
| "IPL serves a useful role in the treatment of acne vulgaris and could reduce treatment costs and pill burden." | ( Annie Malathy, P; Gomathi, N; Mohanan, S; Parveen, B, 2012) |
| "Systemic isotretinoin effectively treats all forms of acne vulgaris." | ( Sinclair, W, 2012) |
| "Dapsone 5% gel for the topical treatment for acne vulgaris was recently introduced in Canada." | ( Tan, J, 2012) |
| "Topical retinoids are highly effective treatments for acne vulgaris." | ( Berger, RS; Grossman, RM; Jorizzo, JL; Kim, YH; Martin, AG; Nighland, M; Nyirady, J; Pandya, AG; Schulz, KK; Strauss, JS, 2001) |
| "Minocycline is an effective treatment of acne vulgaris, especially for inflammatory forms." | ( Bamberg, C; Gross, G; Laskowski, J; Zimmermann, R, 2003) |
| "The effectiveness of treatment for acne vulgaris cannot be determined due to the small sample populations involved in the trials." | ( Farquhar, C; Jepson, R; Lee, O; Toomath, R, 2003) |
| "While isotretinoin, used to treat acne vulgaris, has not been demonstrated to be associated with depression or suicide, the possibility of a relatively rare idiosyncratic adverse effect remains." | ( Magin, P; Pond, D; Smith, W, 2005) |