The class of beta-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6.
ChEBI ID: 46633
| Member | Definition | Role |
|---|---|---|
| 3-[5-(Dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | 3-[5-(Dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | |
| antibiotic ps 6 | PS-6 | |
| bo 2727 | BO 2727 | |
| doripenem | doripenem | |
| imipenem | imipenem hydrate | |
| imipenem, anhydrous | A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup. | imipenem zwitterion; imipenem |
| l 084 | tebipenem pivoxil | |
| ljc 10627 | A carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents respectively. | biapenem |
| oa 6129a | OA-6129 A | |
| ps 5 | PS-5 | |
| thienamycin | Thienamycin |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 767 (15.32) | 18.7374 |
| 1990's | 1,116 (22.30) | 18.2507 |
| 2000's | 1,288 (25.73) | 29.6817 |
| 2010's | 1,381 (27.59) | 24.3611 |
| 2020's | 453 (9.05) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 458 (8.31%) | 5.53% |
| Reviews | 242 (4.39%) | 6.00% |
| Case Studies | 547 (9.92%) | 4.05% |
| Observational | 22 (0.40%) | 0.25% |
| Other | 4,243 (76.98%) | 84.16% |