Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 7.3842 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 41.2752 | 2 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 19.0323 | 2 | 6 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.5696 | 1 | 5 |
| AR protein | Homo sapiens (human) | Potency | 35.4591 | 9 | 34 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 41.2800 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 12.7583 | 1 | 6 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 18.4396 | 2 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 15.8529 | 1 | 7 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 23.3442 | 2 | 6 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 7.5686 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 14.5829 | 1 | 6 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 17.7828 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.4501 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 68.4501 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 34.0364 | 2 | 9 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 17.4982 | 2 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 18.2563 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 28.7968 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 25.5154 | 2 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 16.5311 | 2 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 165.6674 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 27.7281 | 1 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 16.5311 | 2 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 40.9955 | 2 | 5 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 13.1416 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 6.4329 | 1 | 10 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 13.0403 | 1 | 12 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 12.9249 | 2 | 16 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 16.2094 | 2 | 9 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 29.3225 | 1 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 5.7816 | 3 | 16 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 16.2304 | 1 | 5 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 3.8832 | 1 | 2 |
| endonuclease IV | Escherichia coli | Potency | 15.7142 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 36.1677 | 11 | 46 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 19.9318 | 2 | 5 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 24.8454 | 9 | 32 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 24.1477 | 2 | 11 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 21.0388 | 4 | 11 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 20.2992 | 4 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 11.8464 | 1 | 4 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 34.4220 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 13.1416 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 12.9249 | 1 | 8 |
| geminin | Homo sapiens (human) | Potency | 15.4056 | 4 | 11 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 15.8666 | 2 | 15 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 13.1684 | 2 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 7.8280 | 2 | 5 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 18.4970 | 4 | 11 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 44.0372 | 1 | 3 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 11.5821 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 38.4406 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 37.9125 | 2 | 3 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 15.5215 | 1 | 18 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 4.2460 | 1 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 13.1416 | 1 | 2 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 32.0272 | 2 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 29.1548 | 2 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 7.9433 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 25.4996 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 28.1252 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 13.1416 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 7.9434 | 1 | 4 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 13.1416 | 1 | 2 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 7.6262 | 1 | 9 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 14.2191 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 27.5858 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 7.3438 | 1 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 3.9756 | 1 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 2.7697 | 2 | 12 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 20.8114 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 10.2869 | 2 | 6 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 4.4668 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 58.0479 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 37.9296 | 4 | 9 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 25.9290 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 42.2395 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 26.1596 | 1 | 4 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 37.5780 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 34.4818 | 3 | 12 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 28.2479 | 2 | 3 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 13.6274 | 1 | 6 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 37.3046 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 18.7781 | 5 | 10 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 25.0019 | 4 | 10 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 70.5246 | 3 | 3 |
| polyprotein | Zika virus | Potency | 34.4220 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 15.5215 | 1 | 9 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 8.8985 | 1 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.3838 | 3 | 8 |
| progesterone receptor | Homo sapiens (human) | Potency | 9.1797 | 2 | 5 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 25.7607 | 2 | 9 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 58.0479 | 1 | 2 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 7.0898 | 1 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 33.5320 | 3 | 7 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 18.4183 | 4 | 9 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 19.9029 | 4 | 13 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 21.0521 | 2 | 6 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 21.0521 | 2 | 6 |
| snurportin-1 | Homo sapiens (human) | Potency | 28.1252 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 25.1091 | 1 | 4 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 5.8654 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.9609 | 2 | 19 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 89.1251 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 30.4088 | 2 | 6 |
| Thrombopoietin | Homo sapiens (human) | Potency | 16.7004 | 2 | 8 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 26.9177 | 3 | 19 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 35.6201 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 18.3774 | 5 | 13 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 28.3424 | 1 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 15.5257 | 2 | 12 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 18.7765 | 5 | 9 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 52.9309 | 1 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 44.0372 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 0.3981 | 2 | 2 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 1.2930 | 2 | 8 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 2.3822 | 3 | 5 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.7813 | 4 | 6 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 1.2930 | 2 | 8 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 1.3411 | 5 | 7 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | IC50 | 0.3802 | 2 | 2 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Ki | 0.6603 | 3 | 3 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Ki | 0.6603 | 3 | 3 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 0.0458 | 4 | 7 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 0.8256 | 3 | 7 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.0667 | 16 | 23 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.0509 | 7 | 7 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.0558 | 1 | 4 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.8256 | 3 | 7 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.0356 | 1 | 4 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 0.0673 | 5 | 5 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 0.0069 | 2 | 5 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.8256 | 3 | 7 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.0176 | 7 | 12 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 0.0563 | 6 | 6 |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | Ki | 0.1600 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | IC50 | 1.4125 | 2 | 2 |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | IC50 | 1.4125 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 3A | Mus musculus (house mouse) | Ki | 0.2520 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Ki | 0.1855 | 2 | 2 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | IC50 | 1.4125 | 2 | 2 |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | IC50 | 1.4125 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 3B | Mus musculus (house mouse) | Ki | 0.2520 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Ki | 0.1855 | 2 | 2 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | IC50 | 1.4125 | 2 | 2 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | IC50 | 1.4125 | 2 | 2 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | IC50 | 1.4125 | 2 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0067 | 1 | 4 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.0035 | 1 | 4 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 0.2138 | 1 | 4 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 1.3173 | 4 | 9 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 30.2667 | 1 | 6 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 0.1148 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | Ki | 2.8313 | 5 | 7 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | IC50 | 1.1216 | 1 | 5 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.1547 | 3 | 3 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 0.5820 | 1 | 5 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 0.5768 | 1 | 5 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 0.4074 | 2 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0901 | 3 | 6 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1040 | 4 | 5 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1811 | 3 | 3 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1040 | 4 | 5 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.1918 | 1 | 4 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2700 | 2 | 2 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.0942 | 1 | 4 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1040 | 4 | 5 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 0.2735 | 3 | 9 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.1176 | 2 | 3 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.1842 | 2 | 5 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.2873 | 2 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.0891 | 2 | 8 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.1176 | 2 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.0814 | 1 | 4 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.2873 | 2 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 0.3701 | 4 | 10 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.1176 | 2 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.1059 | 2 | 5 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 3.2873 | 2 | 3 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 14.4000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | Ki | 300.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 280.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 370.0000 | 2 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 0.3380 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 22.7195 | 1 | 2 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 18.6136 | 1 | 2 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | Ki | 0.5000 | 1 | 3 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 3.2092 | 10 | 10 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 5.4160 | 5 | 5 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 10.9650 | 2 | 2 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0270 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 146.6033 | 5 | 21 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 16.9009 | 3 | 3 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 124.9250 | 1 | 8 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | Ki | 295.0000 | 1 | 1 |
| Chromaffin granule amine transporter | Homo sapiens (human) | IC50 | 0.0500 | 2 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 0.0079 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.0079 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | Ki | 49.9000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 2 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 204.0000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 1.9000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 14.2000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 19.3000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 2.7256 | 7 | 8 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 2 |
| D | Rattus norvegicus (Norway rat) | IC50 | 3.3176 | 2 | 3 |
| D | Rattus norvegicus (Norway rat) | Ki | 1.4200 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 0.4572 | 1 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.2006 | 2 | 5 |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 1 | 1 |
| D(1B) dopamine receptor | Homo sapiens (human) | Ki | 0.1700 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 3.1556 | 4 | 5 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 2.6354 | 3 | 3 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.7044 | 4 | 5 |
| D(2) dopamine receptor | Mus musculus (house mouse) | Ki | 0.7260 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.7895 | 3 | 4 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 1.6552 | 3 | 5 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.6432 | 3 | 5 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 1.5240 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | IC50 | 3.3113 | 2 | 2 |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.0340 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 160.0000 | 1 | 1 |
| Endothelin receptor type B | Homo sapiens (human) | Ki | 0.0631 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Ki | 0.0631 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 0.1148 | 1 | 1 |
| Fatty acid-binding protein, heart | Homo sapiens (human) | IC50 | 0.3670 | 1 | 1 |
| G-protein coupled receptor | Apis mellifera (honey bee) | IC50 | 73.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | IC50 | 60.0000 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 0.0309 | 3 | 6 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0002 | 1 | 10 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.0043 | 4 | 7 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.8480 | 1 | 5 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 1.3573 | 1 | 3 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 1.3350 | 1 | 3 |
| Histamine H3 receptor | Homo sapiens (human) | Ki | 3.0000 | 2 | 2 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | Ki | 5.0000 | 1 | 1 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 5.0120 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Krueppel-like factor 10 | Homo sapiens (human) | IC50 | 100.0000 | 2 | 2 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Ki | 0.5240 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | Ki | 0.5240 | 1 | 1 |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 4.1520 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 2.0430 | 2 | 2 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 0.6770 | 1 | 4 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 4 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 0.1632 | 1 | 4 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 61.3985 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.0323 | 1 | 4 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.3670 | 1 | 4 |
| Muscarinic acetylcholine receptor M2 | Sus scrofa (pig) | Ki | 0.2344 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 0.8458 | 1 | 4 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 0.1794 | 1 | 4 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.9758 | 1 | 4 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.1359 | 1 | 4 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 0.3028 | 1 | 4 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 0.6200 | 2 | 5 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 0.2177 | 1 | 4 |
| Nociceptin receptor | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 22.7195 | 1 | 2 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 18.6136 | 1 | 2 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 435.3333 | 2 | 3 |
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | IC50 | 22.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 5.7276 | 20 | 37 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 18.6136 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 2.7000 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | Ki | 0.1600 | 1 | 2 |
| Quinolone resistance protein NorA | Staphylococcus aureus | IC50 | 8.5429 | 7 | 7 |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | Ki | 2.1070 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 1.0437 | 2 | 3 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 4.6315 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.3430 | 1 | 1 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 8.9000 | 3 | 3 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 6.6800 | 4 | 4 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 11.8000 | 2 | 2 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 7.9000 | 4 | 4 |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | IC50 | 170.4120 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 389.0225 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 269.5765 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 250.0945 | 1 | 2 |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | IC50 | 0.2000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 1.4296 | 51 | 78 |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | Ki | 5.4250 | 2 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 24.4135 | 27 | 43 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 5.6016 | 53 | 61 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.7590 | 36 | 47 |
| Sodium-dependent noradrenaline transporter | Mus musculus (house mouse) | Ki | 0.0140 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.6643 | 57 | 76 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.9278 | 50 | 63 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.5453 | 59 | 73 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 1.6598 | 21 | 25 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.3240 | 56 | 67 |
| Sodium-dependent serotonin transporter | Mus musculus (house mouse) | Ki | 0.0235 | 2 | 2 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.4495 | 23 | 34 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 16.7500 | 2 | 2 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 11.4000 | 1 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 33.3843 | 4 | 7 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 5.3600 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 9.9500 | 2 | 2 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 16.0000 | 1 | 1 |
| Solute carrier family 22 member 3 | Rattus norvegicus (Norway rat) | IC50 | 68.0000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 28.0000 | 1 | 2 |
| Solute carrier family 22 member 4 | Rattus norvegicus (Norway rat) | IC50 | 80.0000 | 1 | 1 |
| Sphingomyelin phosphodiesterase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Sulfotransferase 1A1 | Homo sapiens (human) | Ki | 80.0000 | 1 | 2 |
| Sulfotransferase 2A1 | Homo sapiens (human) | Ki | 80.0000 | 1 | 2 |
| Synaptic vesicular amine transporter | Homo sapiens (human) | IC50 | 0.0147 | 3 | 3 |
| Synaptic vesicular amine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0177 | 1 | 10 |
| Synaptic vesicular amine transporter | Bos taurus (cattle) | Ki | 0.0010 | 1 | 1 |
| Synaptic vesicular amine transporter | Homo sapiens (human) | Ki | 0.3484 | 3 | 3 |
| Transporter | Rattus norvegicus (Norway rat) | IC50 | 3.3909 | 18 | 21 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 1.4482 | 21 | 30 |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | Ki | 0.1735 | 2 | 3 |
| Type-1 angiotensin II receptor | Bos taurus (cattle) | IC50 | 0.1800 | 1 | 1 |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2100 | 1 | 1 |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | Ki | 0.5000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 8.3000 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 9.9500 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 9.9500 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 9.9500 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 9.9500 | 2 | 2 |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | IC50 | 16.4000 | 1 | 5 |