tetracycline has been researched along with flomoxef* in 1 studies
1 other study(ies) available for tetracycline and flomoxef
| Article | Year |
|---|---|
Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model.
The availability of a silkworm larva infection model to evaluate the therapeutic effectiveness of antibiotics was examined. The 50% effective doses (ED50) of D-cycloserine against the Staphylococcus aureus ddlA mutant-mediated killing of larvae were remarkably lower than those against the parental strain-mediated killing of larvae. Changes in MICs and ED50 of other antibiotics were negligible, suggesting that these alterations are d-cycloserine selective. Therefore, this model is useful for selecting desired compounds based on their therapeutic effectiveness during antibiotic development. Topics: Animals; Anti-Bacterial Agents; Bombyx; Cephalosporins; Chloramphenicol; Cycloserine; Inhibitory Concentration 50; Larva; Microbial Sensitivity Tests; Staphylococcus aureus; Tetracycline; Vancomycin | 2009 |