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beta-diketone
A diketone in which the two keto groups are separated by a single carbon atom.
ChEBI ID: 67265
Members (28)
| Member | Definition | Role |
|---|---|---|
| 1,3-cyclohexanedione | A cyclohexanedione carrying oxo substituents at positions 1 and 3. | cyclohexane-1,3-dione |
| 1,3-indandione | A member of the class of indanones that is indane in which the hydrogens at positions 2 and 4 have been replaced by oxo groups. | 1,3-indandione |
| 2-[(4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethylcyclohexane-1,3-dione | 2-[(4,4-dimethyl-2,6-dioxocyclohexyl)methyl]-5,5-dimethylcyclohexane-1,3-dione | |
| 2,2'-methylenebis(1,3-cyclohexanedione) | 2-[(2,6-dioxocyclohexyl)methyl]cyclohexane-1,3-dione | |
| 3-methyl-2,4-nonanedione | 3-Methyl-2,4-nonanedione | |
| 4-(3-methyl-5-isoxazolyl)-5-phenylcyclohexane-1,3-dione | 4-(3-methyl-5-isoxazolyl)-5-phenylcyclohexane-1,3-dione | |
| 5-(2-furanyl)cyclohexane-1,3-dione | 5-(2-furanyl)cyclohexane-1,3-dione | |
| acetylacetone | A beta-diketone that is pentane in which the hydrogens at positions 2 and 4 are replaced by oxo groups. | acetylacetone |
| acetylpyruvic acid | A dioxo monocarboxylic acid that is pentanoic acid carrying two oxo groups at positions 2 and 4. | acetylpyruvic acid |
| alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile) | A beta-diketone and nitrile resulting from the the degradation of the isoxazole ring of isoxaflutole. The active herbicide of the proherbicide isoxaflutole. | 2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione |
| anisindione | A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position. | anisindione |
| berkeleydione | A meroterpenoid found in Penicillium rubrum. It has been shown to exhibit inhibitory activity against caspase-1. | berkeleydione |
| berkeleytrione | A meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1. | berkeleytrione |
| bisdemethoxycurcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups. | bisdemethoxycurcumin |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| demethoxycurcumin | A beta-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior. | demethoxycurcumin |
| dibenzoylmethane | A beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects. | dibenzoylmethane |
| fumarylacetoacetate | 4-fumarylacetoacetic acid | |
| gingerdione | [6]-Gingerdione | |
| maleylpyruvate | 3-maleylpyruvic acid | |
| mitorubrin | An azaphilone that is 7,8-dihydro-6H-2-benzopyran substituted by a methyl group at position 7, oxo groups at positions 6 and 8, a propenyl group at position 3 and a (2,4-dihydroxy-6-methylbenzoyl)oxy group at position 7. | mitorubrin |
| ninhydrin | A member of the class of indanones that is indane-1,3-dione bearing two additional hydroxy substituents at position 2. | ninhydrin |
| phenindione | phenindione | |
| quinophthalone | A quinoline derivative with a 1,3-dioxoindan-2-yl substituent at C-2. | quinoline yellow |
| succinylacetoacetate | An alpha,omega-dicarboxylic acid that is suberic acid which oxo groups replace the hydrogens at positions 3 and 5. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia. | 3,5-dioxooctanedioic acid |
| succinylacetone | A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia. | 4,6-dioxoheptanoic acid |
| tetrahydrocurcumin | A beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds. | tetrahydrocurcumin |
| tetrahydroxycurcumin | A beta-diketone that is curcumin in which the two methoxy groups have been replaced by hydroxy groups. It is a metabolite of curcumin. | tetrahydroxycurcumin |
Research
Studies (18,139)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,168 (6.44) | 18.7374 |
| 1990's | 515 (2.84) | 18.2507 |
| 2000's | 2,661 (14.67) | 29.6817 |
| 2010's | 9,081 (50.06) | 24.3611 |
| 2020's | 4,714 (25.99) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 664 (3.42%) | 5.53% |
| Reviews | 1,824 (9.40%) | 6.00% |
| Case Studies | 231 (1.19%) | 4.05% |
| Observational | 9 (0.05%) | 0.25% |
| Other | 16,673 (85.94%) | 84.16% |