A member of the class of imidazoles that is 1,3-dihydroimidazole-2-thione and its derivatives by substitution.
Member | Definition | Role |
3-(2-methoxyphenyl)-4-phenyl-1H-imidazole-2-thione | | 3-(2-methoxyphenyl)-4-phenyl-1H-imidazole-2-thione |
3,5-bis(4-methoxyphenyl)-1H-imidazole-2-thione | | 3,5-bis(4-methoxyphenyl)-1H-imidazole-2-thione |
4-(4-chlorophenyl)-3-(phenylmethyl)-1H-imidazole-2-thione | | 4-(4-chlorophenyl)-3-(phenylmethyl)-1H-imidazole-2-thione |
4-(4-chlorophenyl)-3-phenyl-1H-imidazole-2-thione | | 4-(4-chlorophenyl)-3-phenyl-1H-imidazole-2-thione |
4-(4-methylphenyl)-3-phenyl-1H-imidazole-2-thione | | 4-(4-methylphenyl)-3-phenyl-1H-imidazole-2-thione |
4,5-dimethyl-3-(2-oxolanylmethyl)-1H-imidazole-2-thione | | 4,5-dimethyl-3-(2-oxolanylmethyl)-1H-imidazole-2-thione |
5-(3-nitrophenyl)-3-phenyl-1H-imidazole-2-thione | | 5-(3-nitrophenyl)-3-phenyl-1H-imidazole-2-thione |
5-(3,4-dimethoxyphenyl)-3-(4-ethoxyphenyl)-1H-imidazole-2-thione | | 5-(3,4-dimethoxyphenyl)-3-(4-ethoxyphenyl)-1H-imidazole-2-thione |
5-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-imidazole-2-thione | | 5-(3,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-1H-imidazole-2-thione |
5-(4-nitrophenyl)-3-phenyl-1H-imidazole-2-thione | | 5-(4-nitrophenyl)-3-phenyl-1H-imidazole-2-thione |
carbimazole | A member of the class of imidazoles that is methimazole in which the nitrogen bearing a hydrogen is converted into its ethoxycarbonyl derivative. A prodrug for methimazol, carbimazole is used for the treatment of hyperthyroidism. | carbimazole |
ergothioneine | A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a thioxo group. | ergothioneine thione form; ergothioneine |
methimazole | A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen. | methimazole |
nepicastat | A member of the class of 1,3-dihydroimidazole-2-thiones that is 1,3-dihydro-2H-imidazole-2-thione in which one of the nitrogens is substituted by a 5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl group while the carbon adjacent to it is substituted by an aminomethyl group (the S enantiomer). It is a potent and selective inhibitor of both bovine and human dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. | nepicastat |