Any member of a group of vitamers that belong to the chemical structural class called flavins that exhibit biological activity against vitamin B2 deficiency. Symptoms associated with vitamin B2 deficiency include glossitis, seborrhea, angular stomaitis, cheilosis and photophobia. The vitamers include riboflavin and its phosphate derivatives (and includes their salt, ionised and hydrate forms).
ChEBI ID: 176838
| Member | Definition | Role |
|---|---|---|
| flavin mononucleotide | A flavin mononucleotide that is riboflavin (vitamin B2) in which the primary hydroxy group has been converted to its dihydrogen phosphate ester. | FMN |
| flavin-adenine dinucleotide | A flavin adenine dinucleotide in which the substituent at position 10 of the flavin nucleus is a 5'-adenosyldiphosphoribityl group. | FAD |
| riboflavin | D-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. | riboflavin |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5,115 (39.86) | 18.7374 |
| 1990's | 1,382 (10.77) | 18.2507 |
| 2000's | 1,997 (15.56) | 29.6817 |
| 2010's | 3,096 (24.12) | 24.3611 |
| 2020's | 1,244 (9.69) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 403 (2.85%) | 5.53% |
| Reviews | 722 (5.10%) | 6.00% |
| Case Studies | 353 (2.49%) | 4.05% |
| Observational | 34 (0.24%) | 0.25% |
| Other | 12,638 (89.31%) | 84.16% |