Any member of the class of pyridines that carries at least one methyl substituent.
| Member | Definition | Role |
|---|
| 1-(6-methyl-2-pyridinyl)-3-(2-phenylethyl)thiourea | | 1-(6-methyl-2-pyridinyl)-3-(2-phenylethyl)thiourea |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4. | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| 1-methylpyridinium | | N-methylpyridinium |
| 2-(Hydroxymethyl)-6-methylpyridin-3-ol | | 2-(Hydroxymethyl)-6-methylpyridin-3-ol |
| 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide | A member of the class of quinazolines that is quinazoline substituted by {3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}amino and 3-(2-methoxyacetamido)prop-1-en-1-yl groups at positions 4 and 6, respectively. | 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide |
| 2-methyl-3-hydroxypyridine-5-carboxylic acid | The 5-hydroxy-6-methyl derivative of nicotinic acid. | 5-hydroxy-6-methylpyridine-3-carboxylic acid |
| 2,4-dimethylpyridine | | 2,4-Dimethylpyridine |
| 2,6-lutidine | A member of the class of methylpyridines that is pyridine carrying methyl substituents at positions 2 and 6. | 2,6-dimethylpyridine |
| 3-hydroxy-2-methyl-1-(phenylmethyl)-4-pyridinone | | 3-hydroxy-2-methyl-1-(phenylmethyl)-4-pyridinone |
| 4-deoxypyridoxine | A pyridine ring substituted with methyl groups at positions 2 and 4, a hydroxyl at position 3, and a hydroxymethyl group at position 5. | 4-deoxypyridoxine |
| 5-bromo-N-(5-methyl-2-pyridinyl)-2-thiophenesulfonamide | | 5-bromo-N-(5-methyl-2-pyridinyl)-2-thiophenesulfonamide |
| 5-methyl-7-(trifluoromethyl)-2-thiazolo[4,5-b]pyridinamine | | 5-methyl-7-(trifluoromethyl)-2-thiazolo[4,5-b]pyridinamine |
| 6-methyl-2-(phenylethynyl)pyridine | A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. | 2-methyl-6-(phenylethynyl)pyridine |
| ac 263,222 | A pyridinemonocarboxylic acid that is 5-methylpyridine-3-carboxylic acid which is substituted at position 2 by a 4,5-dihydro-imidazol-2-yl group, which in turn is substituted at positions 4, 4, and 5 by isopropyl, methyl, and oxo groups, respectively. | 5-methyl-2-[4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]pyridine-3-carboxylic acid |
| gamma-collidine | | 2,4,6-Trimethylpyridine |
| gsk2656157 | A pyrrolopyrimidine that is 7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine which has been substituted at position 5 by a 4-fluoro-2,3-dihydro-1H-indol-5-yl group, the nitrogen of which has been acylated by a (6-methylpyridin-2-yl)acetyl group. An orally bioavailable PERK inhibitor. | GSK2656157 |
| latrepirdine | | latrepirdine |
| ly-2157299 | A pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma. | LY-2157299 |
| n'-methyl-2-pyridone-5-carboxamide | A pyridone that is 2-pyridone substituted with a carboxamide group at C-5 and a methyl group at N-1. | N-methyl-6-pyridone-3-carboxamide |
| piericidin a | A member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductase | piericidin A |
| pyridoxal | A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxal |
| pyridoxal phosphate | The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. | pyridoxal 5'-phosphate |
| pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | An arenesulfonic acid that is pyridoxal 5'-phosphate carrying an additional 2,4-disulfophenylazo substituent at position 6. | 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid |
| pyridoxamine phosphate | A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. | pyridoxamine 5'-phosphate |
| pyridoxic acid | A methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine. | 4-pyridoxic acid |
| pyridoxine | A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxine |
| pyrithioxin | | pyritinol |
| pyritinol hydrochloride | | Pyrithioxin dihydrochloride |
| sb-505124 | A member of the class of imidazoles carrying tert-butyl, 1,3-benzodioxol-5-yl and 6-methylpyridin-2-yl substituents at positions 2, 4 and 5 respectively. | SB 505124 |
| sotorasib | A pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRAS(G12C) mutations. | sotorasib |