Page last updated: 2024-08-05 10:57:37

diarylmethane

Any compound containing two aryl groups connected by a single C atom.

ChEBI ID: 51614

Members (181)

MemberDefinitionRole
(2-amino-5-chlorophenyl)(phenyl)methanone oxime(2-amino-5-chlorophenyl)(phenyl)methanone oxime
(8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-(1-oxo-3,3-diphenylpropyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide(8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-(1-oxo-3,3-diphenylpropyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide
[4-(diphenylmethyl)-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone[4-(diphenylmethyl)-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
[4-(diphenylmethyl)-1-piperazinyl]-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone[4-(diphenylmethyl)-1-piperazinyl]-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone
1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine1-(1,4-dioxan-2-yl)-N-[[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl]-N-methylmethanamine
1-[4-(3-chlorophenyl)-1-piperazinyl]-3-(diphenylmethyl)oxy-2-propanol1-[4-(3-chlorophenyl)-1-piperazinyl]-3-(diphenylmethyl)oxy-2-propanol
1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine
1-ethyl-3-[(1-oxo-2,2-diphenylethyl)amino]thiourea1-ethyl-3-[(1-oxo-2,2-diphenylethyl)amino]thiourea
1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol
1,1-bis(4-hydroxyphenyl)cyclohexaneBisphenol Z
1,1-Bis(4-hydroxyphenyl)ethane1,1-Bis(4-hydroxyphenyl)ethane
1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene
1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane
1,5-anhydro-1-(5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl)-1-thioglucitolluseogliflozin
2-(3,3-diphenylpropylamino)acetamide2-(3,3-diphenylpropylamino)acetamide
2-(5-bromo-3-nitro-1,2,4-triazol-1-yl)-N-(diphenylmethyl)acetamide2-(5-bromo-3-nitro-1,2,4-triazol-1-yl)-N-(diphenylmethyl)acetamide
2-(cyclohexylamino)-N-[(diphenylmethylene)amino]propanamide2-(cyclohexylamino)-N-[(diphenylmethylene)amino]propanamide
2-(phenylmethyl)benzoic acid [2-[4-(difluoromethylthio)anilino]-2-oxoethyl] ester2-(phenylmethyl)benzoic acid [2-[4-(difluoromethylthio)anilino]-2-oxoethyl] ester
2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
2-[[[4-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester2-[[[4-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester
2-[2-[bis(4-methoxyphenyl)methylidene]hydrazinyl]benzoic acid2-[2-[bis(4-methoxyphenyl)methylidene]hydrazinyl]benzoic acid
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
2,2-bis(4-glycidyloxyphenyl)propaneBisphenol A diglycidyl ether
2,2-diphenylacetic acid (2,6-dimethylphenyl) ester2,2-diphenylacetic acid (2,6-dimethylphenyl) ester
2,2-methylenebis(4-chloro-3-methyl-isopropylphenol)biclotymol
2,2'-bisphenol f2,2'-Bisphenol F
2,2'-methylenebis(4-methyl-6-tert-butylphenol)2,2'-Methylenebis(4-methyl-6-tert-butylphenol)
3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanone3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(3-methyl-1-piperidinyl)-1-propanone
3-(2'-aminobenzhydryloxy)tropane2-[(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy-phenylmethyl]aniline
3-(5-chloro-2-hydroxyphenyl)-3-phenyl-N-[(4-propan-2-yloxyphenyl)methyl]propanamide3-(5-chloro-2-hydroxyphenyl)-3-phenyl-N-[(4-propan-2-yloxyphenyl)methyl]propanamide
3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione
3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane
3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acid3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acid
3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane
3-bromo-5-[[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-oxomethyl]-2-pyranone3-bromo-5-[[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-oxomethyl]-2-pyranone
3-hydroxy-2,2-diphenylpropanoic acid3-hydroxy-2,2-diphenylpropanoic acid
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide4-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide
4-[1-(4-hydroxyphenyl)ethenyl]phenol4-[1-(4-hydroxyphenyl)ethenyl]phenol
4-[hydroxy(diphenyl)methyl]-N-(2-phenylethyl)-1-piperidinecarbothioamide4-[hydroxy(diphenyl)methyl]-N-(2-phenylethyl)-1-piperidinecarbothioamide
4-cumylphenolp-Cumylphenol
4-oxo-3-[(1-oxo-2,2-diphenylethyl)amino]-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl ester4-oxo-3-[(1-oxo-2,2-diphenylethyl)amino]-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl ester
4,4'-bisphenol fA bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.bisphenol F
4,4'-methylene bis(2-methylaniline)4,4'-Methylene bis(2-methylaniline)
5-[4-(diphenylmethyl)-1-piperazinyl]-2-(2-methoxyphenyl)-4-oxazolecarbonitrile5-[4-(diphenylmethyl)-1-piperazinyl]-2-(2-methoxyphenyl)-4-oxazolecarbonitrile
adiphenine2,2-diphenylacetic acid 2-(diethylamino)ethyl ester
adrafiniladrafinil
ae0047Vatanidipine hydrochloride
aminopentamide4-(dimethylamino)-2,2-diphenylpentanamide
amn082A diamine that is ethane-1,2-diamine in which both amino groups are substituted by diphenylmethyl groups. It is an allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7).N,N'-bis(diphenylmethyl)ethane-1,2-diamine
amperozideA member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs.amperozide
amphenone bAmphenone B
aurinAurin
azacyclonoldiphenyl(4-piperidinyl)methanol
b 844-39Niguldipine
beclobratebeclobrate
benactyzine2-hydroxy-2,2-diphenylacetic acid 2-(diethylamino)ethyl ester
benproperine1-[1-[2-(phenylmethyl)phenoxy]propan-2-yl]piperidine
benzomethaminebenzomethamine
benztropine(1R,5S)-3-(diphenylmethyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane
bifemelaneN-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine
bisacodylBisacodyl
bisphenol a-glycidyl methacrylateBisphenol A glycidylmethacrylate
bisphenol f diglycidyl etherAn aromatic ether that is bisphenol F where the hydrogens of both hydroxy groups have been replaced by a oxiran-2-ylmethyl group.bisphenol F diglycidyl ether
budipinebudipine
butinolinebutinoline
bw 373u864-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enyl-1-piperazinyl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
captodiaminecaptodiame
carebastinecarebastine
cetirizine dihydrochlorideCetirizine hydrochloride
cgk 7332,2-diphenyl-N-[2,2,2-trichloro-1-[[(4-fluoro-3-nitroanilino)-sulfanylidenemethyl]amino]ethyl]acetamide
chlorcyclizine1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine
chlorfenetholChlorfenethol
chlorobenzilateChlorobenzilate
chlorophacinoneChlorophacinone
chlorphenoxaminechlorphenoxamine
ci 9661-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
cifenlinecibenzoline
cinnarizinecinnarizine
clidinium2-hydroxy-2,2-diphenylacetic acid (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) ester
clofedanolA diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain.clofedanol
clofoctol2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
cloperastine1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine
cloperastine hydrochlorideCloperastine hydrochloride
cogentin3-(diphenylmethyl)oxy-8-methyl-8-azabicyclo[3.2.1]octane
denaverinedenaverine
dexniguldipine(4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-[3-(4,4-diphenyl-1-piperidinyl)propyl] ester O3-methyl ester
dichlorophenDichlorophen
DifeterolDifeterol
dimenhydrinate8-chloro-1,3-dimethyl-7H-purine-2,6-dione 2-(diphenylmethyl)oxy-N,N-dimethylethanamine
dimenoxadoldimenoxadol
dioxadroldioxadrol
diphenadioneDiphenadione
diphenamidDiphenamid
diphenandiphenan
diphenidol hydrochlorideDifenidol hydrochloride
diphenylmethaneA diarylmethane that is methane substituted by two phenyl groups.diphenylmethane
dipipanonedipipanone
dpi 201-1064-[3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-1H-indole-2-carbonitrile
droprenylaminedroprenilamine
embramineembramine
emeproniumemepronium
epicainideEpicainide
fendiline3,3-diphenyl-N-(1-phenylethyl)-1-propanamine
fenpiverinium4-(1-methyl-1-piperidin-1-iumyl)-2,2-diphenylbutanamide
fesoterodinefesoterodine
flumecinolflumecinol
flunarizineflunarizine
flunarizine hydrochlorideFlunarizine hydrochloride
fluspirilene8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
gc 1 compoundSobetirome
gilutensin hydrochlorideEtifelmine hydrochloride
gw 3965GW 3965
homochlorocyclizine1-[(4-chlorophenyl)-phenylmethyl]-4-methyl-1,4-diazepane
imidafenacinimidafenacin
isomethadoneisomethadone
isopropamide iodideIsopropamide
isopropamide iodideIsopropamide iodide
lercanidipinelercanidipine
lercanidipine hydrochlorideLercanidipine hydrochloride
levocetirizine2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid
levomethadyl acetate hydrochlorideLevomethadyl acetate hydrochloride
lidoflazine2-[4-[4,4-bis(4-fluorophenyl)butyl]-1-piperazinyl]-N-(2,6-dimethylphenyl)acetamide
lifarizinelifarizine
lomerizine1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine
lu 208075ambrisentan
mandrax2-Methyl-3-(2-methylphenyl)-3,4-dihydroquinazolin-4-one [2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride
manidipinemanidipine
meclizineMeclizine
mepenzolate2-hydroxy-2,2-diphenylacetic acid (1,1-dimethyl-3-piperidin-1-iumyl) ester
mepenzolate bromideMepenzolate bromide
methadoneA ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.6-(dimethylamino)-4,4-diphenylheptan-3-one
methadyl acetateacetylmethadol
methylene bis(methylanthranilate)2-amino-5-[(4-amino-3-methoxycarbonylphenyl)methyl]benzoic acid methyl ester
mitotaneMitotane
ML-210An N-acylpiperazine that is piperazine substituted by 5-methyl-4-nitro-1,2-oxazole-3-carbonyl and bis(4-chlorophenyl)methyl groups at positions 1 and 4, respectively. It is a glutathione peroxidase 4 (GPX4) inhibitor which induces ferroptosis in cancer cells expressing the RAS oncogene.ML-210
N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamideN-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide
N-(4-fluorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamideN-(4-fluorophenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamide
n-(4,4-diphenyl-3-butenyl)nipecotic acid1-(4,4-diphenylbut-3-enyl)-3-piperidinecarboxylic acid
N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamideN-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide
N-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamideN-[2-[tert-butyl(methyl)amino]ethyl]-N-methyl-2,2-diphenylacetamide
N-[4-[oxo-[(1-oxo-2,2-diphenylethyl)hydrazo]methyl]phenyl]propanamideN-[4-[oxo-[(1-oxo-2,2-diphenylethyl)hydrazo]methyl]phenyl]propanamide
N-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamideN-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamide
n,n,n',n'-tetramethyl-4,4'-methylenedianiline4,4'-Methylenebis(N,N-dimethylaniline)
niguldipine(4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-[3-(4,4-diphenyl-1-piperidinyl)propyl] ester O3-methyl ester
no 7111-[2-[(diphenylmethylene)amino]oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
normethadonenormethadone
o,p'-ddt1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
octocryleneoctocrylene
oxatomideA member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.oxatomide
paracymethadolNoracymethadol
pd 123177PD 123177
penfluridol1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
pf 04971729Ertugliflozin
phenyltoloxaminephenyltoloxamine
pipenzolate2-hydroxy-2,2-diphenylacetic acid (1-ethyl-1-methyl-3-piperidin-1-iumyl) ester
piperidolate2,2-diphenylacetic acid (1-ethyl-3-piperidinyl) ester
piperidolate hydrochloridePiperidolate hydrochloride
pipoxolanpipoxolan
pipradrolpipradrol
pnu 200577Desfesoterodine
poldinepoldine
prenylaminePrenylamine
proadifen2,2-diphenylpentanoic acid 2-(diethylamino)ethyl ester
progabideprogabide
propinoxpargeverine
propiverinePropiverine
propiverine hydrochloridePropiverine hydrochloride
quifenadinequifenadine
r 590226-[2-[4-[(4-fluorophenyl)-phenylmethylidene]-1-piperidinyl]ethyl]-7-methyl-5-thiazolo[3,2-a]pyrimidinone
r 599493-[2-[4-[bis(4-fluorophenyl)methylidene]-1-piperidinyl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
setastinesetastine
tas 3013-[bis(4-methoxyphenyl)methylidene]-1H-indol-2-one
terfenadineTerfenadine
terfenadineFexofenadine hydrochloride
terodilineterodiline
tesmilifeneN,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine
thiphenamiltifenamil
tofenacintofenacin
uk 78282UK 78282
zamifenacin(3R)-1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(diphenylmethyl)oxypiperidine

Research

Studies (31,033)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199010,021 (32.29)18.7374
1990's5,504 (17.74)18.2507
2000's6,454 (20.80)29.6817
2010's6,851 (22.08)24.3611
2020's2,203 (7.10)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials4,414 (12.11%)5.53%
Reviews2,219 (6.09%)6.00%
Case Studies1,987 (5.45%)4.05%
Observational129 (0.35%)0.25%
Other27,701 (76.00%)84.16%