Page last updated: 2024-08-05 11:18:58
organic heterohexacyclic compound
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ChEBI ID: 51914
Members (12)
| Member | Definition | Role |
|---|---|---|
| alpha-solanine | A glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol]. | solanine |
| bielschowskysin | A diterpenoid that is isolated from Pseudopterogorgia kallos and exhibits antimalarial and anticancer activity. | bielschowskysin |
| corynoline | A benzophenanthridine alkaloid that is chelidonine substituted by a methyl group at position 13. Isolated from the aerial parts of Corydalis incisa, it acts as an acetylcholinesterase inhibitor and also exhibits antineoplastic and hepatoprotective activity. | corynoline |
| fumitremorgin a | An organic heterohexacyclic compound that is a mycotoxic indole alkaloid obtained by prenylation of the 10-hydroxy group of verruculogen. | fumitremorgin A |
| go 6976 | Goe 6976 | |
| lactonamycin | An organic heterohexacyclic compound isolated from the culture broth of Streptomyces rishiriensis. It is an antibiotic with antibacterial activity. | lactonamycin |
| limonin | limonin | |
| paxilline | An indole diterpene alkaloid with formula C27H33NO4 isolated from Penicillium paxilli. It is a potent inhibitor of large conductance Ca2(+)- and voltage-activated K(+) (BK)-type channels. | paxilline |
| quinine | An Aspidosperma alkaloid with molecular formula C21H24N2O3 found in the roots of Madagascar periwinkle (Catharanthus roseus, formerly known as Vinca rosea). | lochnericine |
| rebeccamycin | An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens. | rebeccamycin |
| rifaximin | A semisynthetic member of the class of rifamycins and non-systemic gastrointestinal site-specific broad spectrum antibiotic. Used in the treatment of traveller's diarrhoea, hepatic encephalopathy and irritable bowel syndrome. | rifaximin |
| verruculogen | An organic heterohexacyclic compound that is a mycotoxic indole alkaloid isolated from Penicillium and Aspergillus species. | verruculogen |
Research
Studies (2,907)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 33 (1.14) | 18.7374 |
| 1990's | 421 (14.48) | 18.2507 |
| 2000's | 1,243 (42.76) | 29.6817 |
| 2010's | 1,008 (34.67) | 24.3611 |
| 2020's | 202 (6.95) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 10 (0.33%) | 5.53% |
| Reviews | 96 (3.20%) | 6.00% |
| Case Studies | 2 (0.07%) | 4.05% |
| Observational | 1 (0.03%) | 0.25% |
| Other | 2,892 (96.37%) | 84.16% |