Any hydroxy steroid carrying a hydroxy group at position 3.
| Member | Definition | Role |
|---|
| 1,3,5,(10),16-estratetraen-3-ol | A 3-hydroxy steroid that is obtained by formal dehydration at the 17-position of estradiol. | 16-estratetraen-3-ol |
| 11 beta-hydroxyandrosterone | | 3alpha,11beta-Dihydroxy-5alpha-androstane-17-one |
| 11-beta-chloromethyl-estradiol | | 11beta-Chloromethylestradiol |
| 11-hydroxyandrostenedione | | 11-Hydroxyandrostenedione |
| 11-ketoetiocholanolone | | 11-Ketoetiocholanolone |
| 16-ketoestrone | | 16-Ketoestrone |
| 17-desoxyestradiol | A 3-hydroxy steroid resulting from deoxygenation at position 17 of estradiol or estrone. | estra-1,3,5(10)-trien-3-ol |
| 17-methylestradiol | | 17alpha-Methylestradiol |
| 2-methoxyestradiol | A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2. | 2-methoxy-17beta-estradiol |
| 2-methoxyestrone | A 17-oxo steroid that is estrone in which the hydrogen at position 2 has been replaced by a methoxy group. | 2-methoxyestrone |
| 3beta-hydroxy-17-(1h-benzimidazole-1-yl)androsta-5,16-diene | | Galeterone |
| 4-androstene-3,17-diol | | 4-Androstenediol |
| 4-hydroxyestrone | A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4. | 4-hydroxyestrone |
| 4-methoxyestradiol | A 17beta-hydroxy steroid that is 17beta-estradiol in which the hydrogen at position 4 has been replaced by a methoxy group. | 4-methoxy-17beta-estradiol |
| 5-androstene-3,16,17-triol | | 5-Androstenetriol |
| alfatradiol | An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer). | 17alpha-estradiol |
| altrenogest | | Altrenogest |
| androstan-3-ol | | 5alpha-Androstan-3beta-ol |
| androstane-3,17-diol | | androstane-3,17-diol |
| bolasterone | | Bolasterone |
| calusterone | | calusterone |
| clostebol | | clostebol |
| d-4-chloro-17 beta-hydroxy-3-oxo-17 alpha-methylandrosta-1,4-diene | | 4-Chloromethandienone |
| dimethisterone | | Dimethisterone |
| equilenin | A 3-hydroxy steroid that is estrone which carries two double bonds at positions 6 and 8. It is found in the urine of pregnant mare's and extensively used for estrogen replacement therapy in postmenopausal women. | equilenin |
| equilin | | equilin |
| estetrol | A 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. | estetrol |
| estradiol 17-sulfate | A steroid sulfate obtained by the formal condensation of sulfuric acid with the 17-hydroxy group of 17beta-estradiol. | 17beta-estradiol 17-sulfate |
| estradiol-17 beta-glucuronide | A steroid glucosiduronic acid that consists of 17beta-estradiol having a beta-glucuronyl residue attached at position 17 via a glycosidic linkage. | 17beta-estradiol 17-glucosiduronic acid |
| estriol | A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer). | estriol |
| estriol-16 alpha-glucuronide | A steroid glucosiduronic acid that is estriol in which the phenolic hydrogen has been replaced by a beta-D-glucuronyl residue. | estriol 16-O-(beta-D-glucuronide) |
| estrone | A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17. | estrone |
| ethinyl estradiol | A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. | 17alpha-ethynylestradiol |
| fulvestrant | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. | fulvestrant |
| ici 164384 | A 3-hydroxy steroid that is 17beta-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines. | ICI-164384 |
| methandriol | | Methandriol |
| methenolone | | methenolone |
| moxestrol | | Moxestrol |
| pregna-4,17-diene-3,16-dione | | E-Guggulsterone |
| quinbolone | | quinbolone |
| ru 58668 | A 17beta-hydroxy steroid that is 17beta-estradiol in the the hydrogen at the 11beta position has been replaced by a p-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl group. RU 58668 is a pure anti-estrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). | RU 58668 |
| stenbolone | | Stenbolone |
| stigmastanol | A 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group. | stigmastanol |
| testosterone | | 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
| tetrahydrogestrinone | | Tetrahydrogestrinone |
| tipredane | | Tipredane |
| trilostane | An epoxy steroid that is 3,17beta-dihydroxy-5alpha-androst-2-ene-2-carbonitrile in which the oxygen of the epoxy group is joined to the 4alpha and 5 alpha positions. | trilostane |