| "Local toxic effects were seen in wounds treated with 0." | ( Hallmans, G, 1978) |
| "The necessity for treating minor injuries and abrasions is stressed." | ( Rutter, JF, 1977) |
| "The effect of trauma (femur fracture) on protein synthesis in rats given four different parenterally administered nutrient formulations ("diets") was investigated." | ( Leskiw, MJ; Oram-Smith, JC; Stein, TP; Wallace, HW, 1977) |
| "When in doubt, access to a Trauma Registry (computerized) can be exceedingly valuable to assist in selecting the most effective treatment for a given clinical problem." | ( Baker, RJ, 1975) |
| "In order to clarify the effect of trauma and treatment as stresses on myocardia, we examined histological changes of myocardia in victims who received various kinds of traumata and treatments." | ( Ogura, Y; Wakasugi, C; Yoshida, K, 1992) |
| "Seven patients with trauma to eight digits and one toe went untreated for arterial stasis, with subsequent development of posttraumatic changes in skin coloration." | ( Fukui, A; Inada, Y; Maeda, M; Mine, T; Mizumoto, S; Tamai, S, 1992) |
| "Tissue trauma in irradiated hosts significantly increases mortality from bacterial infections and makes antimicrobial treatments more difficult than when individuals are subjected to trauma or radiation alone." | ( Brook, I; Elliott, TB; Ledney, GD; Madonna, GS; Moore, MM, 1992) |
| "Most of these wounds have a physiologic basis and are treated according to basic wound-healing principles." | ( Cohen, M; Dolezal, RF; Marschall, MA; Marschall, SF, 1991) |
| "Nine cases of traumatic aortic tear treated during 1986-1987 were reviewed." | ( Eddy, AC; Pavlin, DJ; Pavlin, EG; Van Norman, GA, 1991) |
| "Eighteen trauma patients were prospectively randomized to PEP (n = 9) or PRO (n = 9) enteral diets administered via nasoduodenal tubes (within 1-2 days of injury)." | ( Ditesheim, JA; Meredith, JW; Zaloga, GP, 1990) |
| "In a multicenter study, a total of 100 wounds in 94 patients were treated with Iruxol ointment over a period of 3 weeks." | ( Paul, E, 1990) |
| "A multiple trauma patient failed treatment with ceftazidime and amikacin for bacteremia and meningitis due to a Klebsiella pneumoniae strain that produced a novel, plasmid-mediated beta-lactamase." | ( Howell, AW; Jorgensen, JH; Longfield, RN; Smith, CE; Tillman, BS, 1990) |
| "Topical application of TGF-beta to wounds of rats treated with doxorubicin increases collagen mRNA levels to normal or supranormal levels." | ( Bernstein, E; Buresh, C; Director, E; Kasid, A; Norton, JA; Salomon, GD, 1990) |
| "Study of 208 consecutively treated injuries to carpenters in northwestern Vermont revealed an annual injury rate of 13." | ( Payne, SR; Skelly, JM; Waller, JA, 1989) |
| "Twelve patients with traumatic shock caused by a mechanical trauma were treated with narcanti within 6 h after trauma with a single dose 0." | ( Shirokov, DM; Tarelkina, MN; Tsibin, IuN, 1989) |
| "After administration of trauma (leg fracture), a statistically significant difference (P less than 0." | ( Audhya, T; Hollander, CS; Kanie, N; Nakane, T, 1985) |
| "By Day 14, the pair fed animals had wounds similar to those of controls but the Adriamycin-treated animals remained significantly weaker than the other groups." | ( Gamelli, RL; Greenhalgh, DG, 1988) |
| "At 7 days, the wounds treated with the petrolatum-containing dressings had more contraction than wounds dressed with cotton nonadherent film dressings and wounds dressed with rayon/polyethylene dressings." | ( Hughes, KS; Lee, AH; McGuire, JA; Swaim, SF, 1987) |
| "Experimental wounds were subjected to laser treatment every other day for 2 months; control wounds remained untreated." | ( Abergel, RP; Castel, JC; Dwyer, RM; Lyons, RF; Uitto, J; White, RA, 1987) |
| "Thirty-three trauma patients presenting with hypoxemia and normo- or hypocarbia were treated with continuous positive airway pressure (CPAP) via a snug-fitting face mask." | ( Branson, RD; DeHaven, CB; Hurst, JM, 1985) |
| "The records of 197 consecutive multiple trauma patients were reviewed to define the infectious complications of corticosteroids used to treat brain and spinal cord injury." | ( Armitage, JM; DeMaria, EJ; Gann, DS; Kenney, PR; Reichman, W, 1985) |
| "This increased resistance to a lethal trauma in rats conditioned by drummings with concurrent administration of propranolol was confirmed in another lot of rats." | ( Asoh, T; Shirasaka, C; Takeuchi, Y; Tsuji, H, 1983) |
| "15 polytraumatized patients were treated within 5 posttraumatic days with reduced calorie and normal amino-acid supply (17 kcal/kg BW as carbohydrates and 1." | ( Behrendt, W, 1983) |
| "This might be useful for posttraumatic lung treatment." | ( Bahrami, S; Gasser, H; Redl, H; Strohmaier, W, 1984) |
| "These results suggest that in acutely traumatized patients: 1) T3 declines rapidly and remains depressed throughout the illness; 2) continued fall of T4 to subnormal levels is associated with a poor prognosis; and 3) steroid therapy alone cannot explain the acute changes observed in hormone levels." | ( Caplan, ES; Connor, TB; Phillips, RH; Valente, WA; Wiswell, JG, 1984) |
| "In eight polytraumatized ventilated surgical patients studies on substrate utilization and energy expenditure were performed for six days following trauma, while receiving our routinely administered parenteral diet containing 1 g amino acids/kg/d and 6." | ( Grünert, A; Lotz, P; Schmitz, JE, 1981) |
| "The shortest healing time was seen in wounds treated with plastic foil when the contralateral wound was treated with zinc tape." | ( Hallmans, G; Söderberg, T, 1982) |
| "Protective effects were not seen in traumatic shock rats treated with the non-NO-donating parent compound N-acetylpenicillamine." | ( Christopher, TA; Lefer, AM; Ma, XL, 1994) |
| "These findings led us to conclude that trauma caused hemolysis and that the administration of 4,000 U haptoglobin did not improve either the severity of hemolysis or the deteriorated renal tubular function caused by massive transfusion." | ( Gando, S; Tedo, I, 1994) |
| "The study included 35 trauma/general surgery patients (16 in the open suction group, 19 in the closed suction group) who were treated with a total of 276 suctioning procedures (127 open, 149 closed)." | ( Johnson, KL; Johnson, SB; Kearney, PA; MacMillan, NL; McClain, RE; Niblett, JB, 1994) |
| "ethanol therapy were CNS trauma, liver disease, and pancreatitis." | ( Collier, MS; Craft, PP; Cunningham, PR; Foil, MB; Long-Snyder, BM; Patselas, PC, 1994) |
| "Malodor associated with each of 13 wounds was decreased following the initial treatment with topical metronidazole." | ( Poteete, V, 1993) |
| "Patients with severe trauma and illness were treated at our critical care medical center." | ( Iwaki, H; Kitagishi, H; Mantani, Y; Maruyama, J; Maruyama, K; Matsushima, T; Nakaji, M; Sakata, I; Takahashi, H; Yoshinobu, H, 1993) |
| "We reviewed the course of 70 trauma ICU patients treated over a 28-month period." | ( Brathwaite, CE; Mure, AJ; O'Malley, KF; Ross, SE; Spence, RK, 1993) |
| "Seven patients with posttraumatic headaches refractory to other medical treatment were treated with sumatriptan, 6 mg subcutaneously, at the peak of a headache." | ( Gawel, MJ; Jacobs, H; Rothbart, P, 1993) |
| "Of 520 patients treated for major trauma, 217 (42%) were tested for a variety of drugs." | ( Brookoff, D; Campbell, EA; Shaw, LM, 1993) |
| "Of practical implication in traumatology is the finding that, for both paracetamol and glucocorticoids, almost the same reductions were recorded in swelling and pain whether the drug was administered prior to surgery or 2-3 hours afterwards." | ( Løkken, P; Skjelbred, P, 1993) |
| "All 3 treatments affected traumatic arthritis in horses, but the SH and PSGAG gave better results than the placebo." | ( Gaustad, G; Larsen, S, 1995) |
| "These findings suggest that traumatic injury in the infant rat brain is mediated by endogenous excitotoxins (Glu and aspartate) acting at NMDA receptors and can be substantially mitigated by timely treatment with NMDA receptor antagonists." | ( Ikonomidou, C; Kirby, C; Labruyere, J; Olney, JW; Qin, Y, 1996) |
| "Four cases of trauma, where endogenous ethanol production was suspected to have been occurred in association with medical treatment, are reported." | ( Hashimoto, Y; Moriya, F, 1996) |
| "The rate of ED-treated injuries related to PWC was about 8." | ( Annest, JL; Branche, CM; Conn, JM, 1997) |
| "The endocrine stress response to trauma was modified by preoperative administration of morphine." | ( Carlström, K; Eklund, J; Eriksson-Mjöberg, M; Kristiansson, M; Ölund, A, 1997) |
| "Nontreated males underwent either trauma hemorrhage or sham operation." | ( Angele, MK; Ayala, A; Bland, KI; Chaudry, IH; Cioffi, WG, 1998) |
| "One hundred twelve patients with posttraumatic reflex sympathetic dystrophy were treated using 4 methods: regional intravenous blocks with lignocaine and methylprednisolone, mannitol i." | ( Zyluk, A, 1998) |
| "Next, the experimental skin wounds in mice were infected with 107 CFU of Pseudomonas aeruginosa strain ATCC 27853 and treated locally with the rhG-CSF-containing dressing." | ( Antos-Bielska, M; Cheda, A; Grzybowski, J; Janiak, MK; Lasocki, K; Oldak, E; Pojda, Z; Wrembel-Wargocka, J, 1999) |
| "Treatment of the posttraumatic, vertically shortened upper lip is a difficult surgical problem." | ( Stelnicki, EJ; Zide, B, 1999) |
| "A 12-year-old boy presented with a traumatic hyphaema that failed to settle with the standard treatment." | ( Bolton-Maggs, PH; Hallet, C; Kaye, SB; Shafiq, A; Willoughby, C, 2000) |
| "When wounds are treated with insulin, they are therefore also being treated with zinc." | ( Filler, LE; Greenway, FL; Greenway, SE, 1999) |
| "The willingness of trauma surgeons to push the envelope in treating these most severely afflicted patients has allowed patients who once would have certainly died to lead meaningful lives." | ( Cullinane, DC; Eddy, VA; Morris, JA, 2000) |
| "To treat palmoplantar wounds by using nonpalmoplantar pure epidermal sheets as a graft." | ( Asada, H; Hosokawa, K; Itami, S; Kakibuchi, M; Kubo, T; Sano, S; Tarutani, M; Yamaguchi, Y; Yoshikawa, K, 2001) |
| "Treated wounds received intraincisional particulate bioactive glass prior to closure." | ( Bradley, DM; Coolman, SL; Gillette, RL; Sartin, EA; Swaim, SF, 2001) |
| "Administration of flutamide after trauma-hemorrhage attenuated the depressed endothelial function." | ( Ba, ZF; Bland, KI; Chaudry, IH; Koo, DJ; Ornan, DA; Wang, P, 2001) |
| "The registry was queried for all trauma patients who had anticoagulation therapy as a preinjury condition (PIC)." | ( Cipolle, MD; Pasquale, MD; Seislove, E; Wasser, TE; Wojcik, R, 2001) |
| "Treatment of traumatic corneal abrasion with a contact lens associated with topical NSAID drops sufficiently reduced the pain to allow 80." | ( Caspers-Valu, LE; Dumont, P; Vandorselaer, T; Vauthier, L; Youssfi, H, 2001) |
| "Ninety-seven major trauma victims who underwent tracheal intubation in the field and controlled ventilation of the lungs during prehospital treatment by a Helicopter Emergency Medical Service were assigned randomly to one of two groups: (1) monitor group (n=57) and (2) monitor-blind group (n=40), according to whether the anaesthetist could or could not see an attached capnograph screen." | ( Hauke, J; Helm, M; Lampl, L; Schuster, R, 2003) |
| "Two hours following trauma-hemorrhage, splenocyte proliferation, IL-2, IL-3, IFN-gamma release, and splenic macrophage IL-6 release was maintained in vehicle-treated females." | ( Anantha Samy, TS; Angele, MK; Bland, KI; Chaudry, IH; Knöferl, MW; Schwacha, MG, 2003) |
| "Progesterone administration following trauma-hemorrhage ameliorates the proinflammatory response and, subsequently, the hepatocellular injury via direct action on immunocompetent cells." | ( Bland, KI; Chaudry, IH; Jarrar, D; Kuebler, JF; Rue, LW; Toth, B; Wang, P; Yokoyama, Y, 2003) |
| "The connection between massive psychic trauma and the concept of the death instinct is explored using the basic assumptions that the death instinct is unleashed through and is in a sense characteristic of traumatic experience, and that the concept of the death instinct is indispensable to the understanding and treatment of trauma." | ( Laub, D; Lee, S, 2003) |
| "Twenty-nine patients with severe trauma were randomly divided into two groups: treatment group (15 cases, treated with continuous veno-venous hemofiltration (CVVH) within 12 hours after trauma) and control group (14 cases, not treated with CVVH)." | ( Fu, QH; Lan, GM; Lin, AL, 2004) |
| "Wet treatment of wounds has been used as an "irrigation" method since the seventh century." | ( Eriksson, E; Vranckx, J, 2004) |
| "Evaluating the traumatised patients by objective criteria are of great importance in diagnosis, treatment and prognosis." | ( Avsarogullari, L; Ikizceli, I; Kekec, Z; Sozuer, EM; Yildirim, C, 2004) |
| "Of patients with 1 to 3 wounds, 106 were treated with high-viscosity 2-octylcyanoacrylate and 103 with commercially available devices." | ( Blondeel, PN; Coulthard, P; Debrosse, D; Murphy, JW; Nix, JC; Puls, LE; Theodore, N, 2004) |
| "Patients with angiographically proven traumatic carotid artery dissection and hemodynamic significant hemispheric hypoperfusion, or in whom anticoagulant therapy was either contraindicated or failed clinically, were regarded as being at high risk for stroke and were selected for stenting." | ( Ben-Hur, T; Cohen, JE; Gomori, JM; Rajz, G; Umansky, F, 2005) |
| "For gene transfer in acute wounds, the administration of DOTAP/Chol liposomes appears to be beneficial." | ( Finnerty, CC; Herndon, DN; Jeschke, MG; Klein, D; Pereira, CT; Sandmann, G; Schubert, T, 2005) |
| "Histologic analysis of the wounds showed significantly greater healing at both day 5 and day 8 in response to oxygen therapy." | ( Hijjawi, J; Mogford, J; Mustoe, T; Roy, N; Said, HK, 2005) |
| "The extract treated wounds were found to epithelialize faster and the rate of wound contraction was significantly increased as compared to control wounds." | ( Shetty, S; Somayaji, SN; Udupa, AL; Udupa, SL, 2006) |
| "Administration of E2 or PPT following trauma-hemorrhage produced a significant reduction in systemic TNF-alpha and IL-6 concentrations in WT and KO mice." | ( Chaudry, IH; Choudhry, MA; Hildebrand, F; Hubbard, WJ; Pape, HC; Thobe, BM, 2006) |
| "Sixty-four patients suffering from post-traumatic facial paralysis were managed between 1995 and 2003: 38 (59%) were given medical treatment and 26 (41%) underwent surgery." | ( Barreau, X; Bebear, JP; Bodenez, C; Darrouzet, V; Franco-Vidal, V; Liguoro, D; Rouanet-Larriviere, M, 2006) |
| "The treatment of chronic wounds represents a major cost to society and has a profound effect on the participant's quality of life." | ( Coutts, P; Sibbald, RG, 2005) |
| "Trauma admission data from a Level I trauma center database from July 1, 1996 to January 31, 2002 was downloaded and linked with local weather data from the Archives of the National Oceanic and Atmospheric Administration website, and then analyzed." | ( O'Daniel, JA; Rising, WR; Roberts, CS, 2006) |
| "The extract-treated wounds were found to epithelize faster, and the rate of wound contraction was significantly increased as compared to control wounds (P < ." | ( Shetty, BS; Somayaji, SN; Udupa, AL; Udupa, SL, 2006) |
| "The mean healing times of shallow wounds treated with honey or with IntraSite Gel did not differ significantly (p = 0." | ( Ingle, R; Levin, J; Polinder, K, 2006) |
| "Furthermore, pFn-treated wounds showed increased fibroblast vascularization, collagen regeneration, and epithelialization." | ( Kamiyama, Y; Kwon, AH; Qiu, Z, 2007) |
| "Administration of estradiol following trauma-hemorrhage in wild type mice decreased Kupffer cell TLR4 expression as well as prevented the phosphorylation of p38 MAPK and NF-kappaB." | ( Bland, KI; Chaudry, IH; Choudhry, MA; Frink, M; Hsieh, YC; Hsu, JT; Schwacha, MG; Thobe, BM, 2007) |
| "Inclusion criteria are adult trauma patients with presumed traumatic hemorrhagic shock (systolic arterial blood pressure <90 mmHg) that does not respond to the first 10 min of standard shock treatment (endotracheal intubation, fluid resuscitation and use of vasopressors) after arrival of the first emergency physician at the scene." | ( Braun, J; Dörges, V; Dünser, M; Gries, A; Hasibeder, WR; Helm, M; Lefering, R; Lienhart, HG; Lindner, K; Schlechtriemen, T; Trimmel, H; Ulmer, H; Ummenhofer, W; Voelckel, WG; Waydhas, C; Wenzel, V, 2007) |
| "For the treatment of acute traumatic musculoskeletal injuries, ibuprofen provides the best analgesia among the 3 study medications." | ( Clark, E; Correll, R; Gaboury, I; Passi, B; Plint, AC, 2007) |
| "At 2 hours after trauma-hemorrhage, administration of E2-conjugated to bovine serum albumin (E2-BSA, membrane impermeable) or E2 induced the up-regulation of ER-alpha and GPR30 and attenuated hepatic injury." | ( Chaudry, IH; Choudhry, MA; Frink, M; Hsieh, YC; Schwacha, MG; Suzuki, T; Yu, HP, 2007) |
| "Although trauma-hemorrhage decreased cardiomyocyte PI3K protein expression and Akt phosphorylation (p-Akt), estradiol or estradiol-BSA treatment following trauma-hemorrhage prevented such decreases in cardiomyocyte PI3K protein expressions and p-Akt." | ( Bland, KI; Chaudry, IH; Choudhry, MA; Hsieh, YC; Schwacha, MG; Suzuki, T; Yu, HP, 2007) |
| "Although chronic wounds are common, treatment for these disabling conditions remains limited and largely ineffective." | ( Chen, L; Scott, PG; Tredget, EE; Wu, Y, 2007) |
| "In vivo, soluble LM-332 treated wounds had the highest histology score, but significant differences were not found between wound treatments (p>0." | ( Antezana, MA; Carter, WG; Fukano, Y; Gibran, NS; Muffley, LA; Olerud, JE; Sigle, RO; Sullivan, SR; Underwood, RA; Usui, ML, 2007) |
| "Chronic wounds have traditionally been treated by conservative means." | ( Queen, D; Sibbald, RG; Woo, KY, 2007) |
| "To treat the coagulopathy of trauma, some have suggested early and aggressive use of cryoprecipitate as a source of fibrinogen." | ( Beekley, AC; Dubick, MA; Grathwohl, KW; Hess, JR; Holcomb, JB; Martini, WZ; Perkins, JG; Salinas, J; Simon, CD; Spinella, PC; Stinger, HK; Wade, CE; Wolf, SE, 2008) |
| "Because elevated IL-6 levels after trauma-hemorrhage were decreased with YC-1 treatment, it indicates that IL-6 expression in cardiomyocytes is induced via HIF-1 alpha." | ( Chaudry, IH; Chen, JG; Hsieh, CH; Nickel, EA; Schwacha, MG, 2009) |
| "To examine effects of gender and trauma type on response to treatment with venlafaxine extended release (ER) or placebo in patients with posttraumatic stress disorder (PTSD)." | ( Ahmed, S; Baldwin, DS; Davidson, JR; Musgnung, J; Pedersen, R; Rothbaum, BO; Stein, DJ; Tian, XW, 2008) |
| "placebo), and the treatment-by-trauma-type interaction." | ( Ahmed, S; Baldwin, DS; Davidson, JR; Musgnung, J; Pedersen, R; Rothbaum, BO; Stein, DJ; Tian, XW, 2008) |
| "This study suggests that VAC therapy of traumatic wounds leads to increased local IL-8 and VEGF concentrations, which may trigger accumulation of neutrophils and angiogenesis and thus, accelerate neovascularization." | ( Härter, L; Keel, M; Labler, L; Mica, L; Mihic-Probst, D; Rancan, M, 2009) |
| "While mortality from trauma increases, there has been a decline in mortality from cardiovascular and cerebrovascular diseases which parallels advances in antithrombotic and anticoagulation therapy." | ( George, KJ; Shilad, S; Testerman, GM, 2009) |
| "We extracted the daily number of trauma patients treated at the emergency department over 36 years (1970-2005) from the trauma database of our regional hospital." | ( Fidler, V; Nijsten, MW; Stomp, W; ten Duis, HJ, 2009) |
| "Coagulation defects related to severe trauma, trauma-induced coagulopathy (TIC), have a number of causal factors including: major blood loss with consumption of clotting factors and platelets, and dilutional coagulopathy after administration of crystalloids and colloids to maintain blood pressure." | ( Fries, D; Martini, WZ, 2010) |
| "MLR in mice from sirolimus treated trauma group was stronger than that from sirolimus devoid trauma group (with F value respectively 101." | ( Fan, X; Liang, HP; Tu, YJ; Wang, X; Wei, Q; Yang, X, 2010) |
| "The extract-treated wounds were found to epithelialize faster than controls (P < ." | ( Eversley, M; Kanhai, J; Mayers, S; Milne, DM; Nayak, BS; Rao, AV; Swanston, WH, 2010) |
| "Hemorrhagic shock in the pediatric trauma patient is an uncommon but fundamental problem for the treating clinician." | ( Adamson, WT; Dehmer, JJ, 2010) |
| "Standard skin wounds were performed on 80 Wistar rats, distributed into four groups: no treatment (sham group), laser only (λ670 nm, 9 mW, 0." | ( Fracassi, LD; Marchionni, AM; Medrado, AP; Pinheiro, AL; Reis, SR; Silva, TM, 2010) |
| "The authors showed that wounds treated with e-SVF healed better than those treated with hyaluronic acid." | ( Calabrese, C; Cervelli, V; Curcio, BC; De Angelis, B; Di Stefani, A; Felici, M; Gentile, P; Orlandi, A; Scioli, MG, 2011) |
| "An increasing proportion of trauma patients are on anticoagulation or antiplatelet therapy." | ( Bansal, V; Coimbra, R; Doucet, J; Fortlage, D; Lee, J; Potenza, B, 2011) |
| "These wounds were treated with intradermal injections of tacrolimus (0." | ( Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D, 2011) |
| "Mulesing wounds healed rapidly in a predictable manner, producing long linear scars on either side of the breech and tail by 32-47 days post treatment." | ( Bosward, KL; Canfield, PJ; Hunt, GB; Lepherd, ML; Thomson, PC, 2011) |
| "Fourteen patients (19 wounds) were entered into this prospective study, and 10 patients completed treatment." | ( Ajemian, MS; Brenes, RA; Dudrick, SJ; Macaron, SH; Panait, L, 2011) |
| ": Wounds with posttraumatic bone exposure have been treated with HA dressing alone or in combination with PRP." | ( Cervelli, V; Colicchia, GM; De Angelis, B; Gentile, P; Lucarini, L; Palla, L; Spallone, D, 2011) |
| "Controls had less swollen wounds compared to piglets assigned to treatments M, L and LM (p < 0." | ( Hansson, M; Johansson, G; Lundeheim, N; Nyman, G, 2011) |
| "Investigation was held in 727 cases of traumatological patients treated because of hip replacement or osteosinthesis of limbs." | ( Avazashvili, N; Chikviladze, D; Gachechiladze, Kh; Metreveli, D; Mikeladze, M; Nozadze, T, 2011) |
| "Although trauma-hemorrhage decreased cardiac Akt phosphorylation (p-Akt), resveratrol treatment following trauma-hemorrhage prevented the same decrease in cardiac p-Akt." | ( Lau, YT; Liu, FC; Tsai, YF; Yu, HP, 2012) |
| "The sNAG-treated wounds in CL-treated mice showed higher levels of cell proliferation and not did inhibit angiogenesis." | ( Demcheva, M; Fischer, TH; Gennaoui, A; Matthews, JC; Orgill, DP; Pietramaggiori, G; Scherer, SS; Valeri, CR, 2011) |
| "Cleaning of wounds is considered as the most important part of the local treatment." | ( Juutilainen, V, 2011) |
| "Sixty-one percent (61%) of wounds decreased in size following treatment, but no significant differences were observed between the type and variety of wound pathogens and whether wound size decreased." | ( Adamsen, L; Gottrup, F; Kolmos, HJ; Lund-Nielsen, B; Rorth, M; Tolver, A, 2011) |
| "Topical application of JT on excision wounds caused significantly faster reduction in wound area as compared to the application of modern topical formulation (Neosporin(®)) and untreated control wounds." | ( Menon, S; Pednekar, S; Shailajan, S; Singh, A, 2011) |
| "In experimental corneal wounds, multi-focal areas remained covered by the epithelial basement membrane (BM) after diamond burr treatment in both groups (group 1 = 48% ± 16SD, group 2 = 26% ± 12SD)." | ( da Silva, EG; Ehrhart, EJ; Gionfriddo, JR; Hill, AE; Powell, CC, 2011) |
| "Eight pigs with two wounds each were treated with open-pore structure polyurethane foam or AMD gauze and NPWT of 0 (control) or -80 mm Hg for 72 hours." | ( Gustafsson, L; Ingemansson, R; Lindstedt, S; Malmsjö, M, 2011) |
| "Patients with major blunt trauma orthopedic injuries were administered epoetin alfa or placebo weekly both in hospital and for up to 12 weeks after discharge or until the Hb level was >12." | ( Fabian, TC; Langholff, WK; Luchette, FA; Pasquale, MD; Wolfson, M, 2012) |
| "The treatment of chronic wounds poses a significant challenge for clinicians and patients alike." | ( Ganopolsky, JG; Gilardino, M; Jones, M; Labbé, A; Martoni, C; Prakash, S; Wahl, C, 2012) |
| "The use of TXA in the treatment of traumatic bleeding has the potential to prevent many premature deaths every year." | ( Edwards, P; Ker, K; Kiriya, J; Perel, P; Roberts, I; Shakur, H, 2012) |
| "Future treatment of trauma-induced coagulopathy may be based on systemic antifibrinolytics, local haemostatics and individualized point-of-care-guided rational use of coagulation factor concentrates such as fibrinogen, prothrombin complex concentrate, recombinant factor VIIa and factor XIII." | ( Fries, D; Sorensen, B, 2012) |
| "PCC was used at the discretion of the trauma attending for treatment of coagulopathy, reversal of coumadin, and when recombinant factor VIIa was indicated." | ( Amini, A; Friese, RS; Hays, D; Houdek, M; Joseph, B; Kulvatunyou, N; Latifi, R; O'Keeffe, T; Rhee, P; Wynne, J, 2012) |
| "Fifteen minutes before polytrauma (femur fractures/lung contusion; control: sham), 350 nmol/kg AMD3100, equimolar AMD3100 and ubiquitin (350 nmol/kg each) or vehicle were administered intravenously." | ( Bach, HH; Baker, TA; Gamelli, RL; Majetschak, M; Saini, V; Tripathi, A, 2012) |
| "Three wounds on the backs of the same rats were treated with other dressing materials, namely, Vaseline gauze (group Con), Algisite M(®) (group Alg) and MC (group MC)." | ( Han, DG; Kim, HY; Kim, IH; Kim, MS; Kim, SH; Lee, BK; Lee, YJ; Park, DH; Park, KK; Park, SU; Shim, JS; Sung, WJ, 2014) |
| "We suggest that in trauma patients, etomidate is an independent risk factor for HAP and that the administration of hydrocortisone should be considered after etomidate use." | ( Asehnoune, K; Chatel-Josse, N; Guitton, C; Jaber, S; Jung, B; Lejus, C; Mahe, PJ; Malledant, Y; Masson, F; Renard, B; Roquilly, A; Sébille, V; Seguin, P; Subileau, A; Tellier, AC; Volteau, C, 2012) |
| "Endovascular treatment of posttraumatic arteriovenous fistulae (AVFs) in the lower extremities by means of covered stent-grafts is widely accepted, and many cases have been reported in the iliac-femoral region." | ( Aragón-Sánchez, J; García-Mónaco, R; Marenchino, R; Peralta, O; Rabellino, M; Shinzato, S, 2012) |
| "13,273 trauma patients in the CRASH-2 trial who were treated with tranexamic acid or placebo within three hours of injury and trauma patients enrolled in UK Trauma and Audit Research Network, stratified by risk of death at baseline (<6%, 6-20%, 21-50%, >50%)." | ( Brohi, K; Coats, T; Hunt, BJ; Lecky, F; Perel, P; Prieto-Merino, D; Roberts, I; Shakur, H; Willett, K, 2012) |
| "The increasing understanding of trauma-induced coagulopathy has led to an expansion of treatment strategies in the acute management of trauma patients." | ( Guth, MC; Kaufner, L; Kleber, C; von Heymann, C, 2012) |
| "E2 attenuated the trauma-hemorrhage-induced increase in lung myeloperoxidase activity, edema formation, inflammatory mediator levels, and apoptosis, which was blocked by co-administration of LY294002." | ( Chaudry, II; Chen, TH; Chiang, KC; Hsu, JT; Hwang, TL; Kuo, CJ; Lin, CJ; Yeh, HC; Yeh, TS, 2013) |
| "FA-treated wounds were found to epithelise faster as compared with diabetic wound control group." | ( Ghaisas, MM; Kshirsagar, SB; Sahane, RS, 2014) |
| "Diagnosis and treatment of trauma-induced coagulopathy (TIC) presents a challenge for trauma care providers." | ( Schlimp, CJ; Schöchl, H; Voelckel, W, 2013) |
| "Sixty-four cases of severe trauma (injury severity score ≥20) with stress hyperglycemia (blood glucose >9 mmol/L) were randomly divided into intensive insulin therapy group and conventional therapy group." | ( Dang, W; Liu, HS; Ma, JX; Qin, YH; Su, Q; Wang, M; Yao, YM; Zhang, JB; Zhang, LY; Zhang, X; Zhao, XD, 2013) |
| "Thirty severe trauma patients with injury severity score (ISS) of 16 to 25 were randomly divided into treatment and control groups (n=15 each)." | ( Liu, MH; Su, YP; Tian, J; Wang, T; Wen, L; Xiang, Q, 2013) |
| "In acute traumata a faster symptom relief is found, in chronic conditions the product leads to symptom reduction in case seven where pretreatment has shown insufficient results." | ( Petersen-Braun, M; Wegener, T, 2013) |
| "Pain associated with pediatric trauma is often under-assessed and under-treated in the out-of-hospital setting." | ( Kozak, MA; Miramonti, CM; O'Donnell, DP; Schafer, LC; Stevens, AC; Weinstein, E, 2013) |
| "The current American Trauma Society dosing recommendations for vancomycin for presumptive VAP treatment are inadequate." | ( Christmas, AB; Heniford, BT; Norton, HJ; Schmelzer, TM; Sing, RF, 2013) |
| "In the incision wound model, incision wounds were topically treated with TE gel (2." | ( Panda, V; Thakur, T, 2014) |
| "A sample of 45 chronic wounds of mixed aetiologies presenting in 31 patients were treated with keratin-based novel topical wound healing products." | ( Batzer, AT; Kirsner, RS; Marsh, C, 2016) |
| "In particular, long-standing wounds profited from the treatment with the PA-based hydrogel." | ( Bécherel, PA; Debure, C; Dissemond, J; Eming, SA; Faivre, B; Humbert, P; Kaspar, D; Kerihuel, JC; Plantin, P; Smola, H; Truchetet, F; Véran, Y; Weyandt, G; Zöllner, P, 2014) |
| "Excision wounds of size 500 mm(2) and depth 2 mm were made on the dorsal portion of male Wistar rats (230-250 g) and were used for the study of oral L-glutamine (1 g/kg) treatment on the rate of contraction of wound and epithelisation." | ( Bodhankar, SL; Deshmukh, S; Goswami, S; Hegde, MV; Kandhare, A; Kharat, R; Shinde, S; Zanwar, AA, 2016) |
| "We describe four cases of traumatic, upper limb deep wounds caused by different physical and chemical agents, emphasising the effectiveness of treatment based on topical application of collagenase and hyaluronic acid (HA) before standardised surgical procedures." | ( Fino, P; Onesti, MG; Ponzo, I; Ruggieri, M; Scuderi, N, 2016) |
| "In military and civilian trauma, the IO route is often used to obtain rapid and reliable parenteral access for drug administration." | ( Barnard, EB; Bebarta, VS; Kehoe, AD; Moy, RJ; Smith, JE, 2015) |
| "Following severe trauma, early treatment with propranolol following resuscitation is safe." | ( Alzate, WD; Bible, LE; Gore, AV; Livingston, DH; Mohr, AM; Pasupuleti, LV; Sifri, ZC; Song, KJ, 2014) |
| "It was found that the area of wounds that were treated with cell-seeded nanofibrous scaffolds were smaller compared to other samples." | ( Ahmadi-Taftie, H; Bahrami, SH; Erfani, E; Gholipour-Kanani, A; Joghataie, MT; Kororian, A; Rabbani, S; Samadikuchaksaraei, A, 2014) |
| "In full thickness excisional wounds, the treatment with PLGA-LL37 NP significantly accelerated wound healing compared to PLGA or LL37 administration alone." | ( Chereddy, KK; Comune, M; Ferreira, LS; Her, CH; Lam, MC; Lopes, A; Moia, C; Porporato, PE; Préat, V; Sonveaux, P; Steinstraesser, L; Vanacker, J; Vandermeulen, G; Zhu, H, 2014) |
| "Treatment and management of chronic wounds is a large burden on the health sector and causes substantial suffering for the patients." | ( Butler, É; Lindholm, C; Nilson, B; Oien, RF; Olofsson, TC; Vásquez, A, 2016) |
| "The treatment of chronic skin wounds through the use of a polyhexanide/propyl betaine-based gel, in combination with a secondary dressing, showed significant improvements, such as a 30% reduction of pain at dressing change, the reduction in the size and characteristics of the wounds and a reduction in the levels of exudate." | ( Ciprandi, G; Durante, CM; Gallarini, A; Greco, A; Maino, C; Sidoli, O, 2014) |
| "In most trauma centres, coagulation therapy is established with transfusion of high volumes of fresh frozen plasma." | ( Schlimp, CJ; Schöchl, H; Voelckel, W, 2015) |
| ": Patients with chronic or contaminated wounds treated with split-thickness skin graft." | ( Chen, CC; Chew, KY; Kuo, YR; Wu, CC, 2015) |
| "A total of 136 617 adult trauma patients (2009-2013) were included, with 499 patients reported to be using warfarin therapy at the time of trauma." | ( Battle, CE; Bouamra, O; Edwards, A; Evans, PA; Jenks, T; Lecky, FE; Omar, M, 2015) |
| "Treatment of non-healing wounds represents hitherto a severe dilemma because of their failure to heal caused by repeated tissue insults, bacteria contamination and altered physiological condition." | ( Borgogna, M; Marsich, E; Paoletti, S; Sacco, P; Travan, A, 2015) |
| "Initial treatment of HGF wounds with CMS resulted in faster wound repopulation regardless of nicotine presence." | ( Borke, JL; Chuang, AH; Dinos, ME; Goodin, JL; McPherson, JC; Swiec, GD, 2015) |
| "Therefore, the authors treated wounds infected with methicillin-resistant Staphylococcus aureus (MRSA) in Sprague-Dawley (SD) rats and streptozotocin (STZ)-induced diabetic rats with silver dressings to evaluate the risks of silver." | ( Choi, YS; Lee, YK; Oh, SR; Yeo, ED; Yoon, SA, 2015) |
| "The postoperative concrescence of the wounds was observed daily to evaluate the effects of the different treatments." | ( Chen, H; Chen, J; Liu, R; Nan, W; Wang, M; Xu, Z; Yuan, Z, 2015) |
| "This increase was not evident in wounds treated with Exendin-4(9-39)+Exe4." | ( Bacci, S; De Siena, G; Landucci, E; Laurino, A; Manni, ME; Mocali, A; Musilli, C; Raimondi, L, 2015) |
| "Compared with controls, trauma-hemorrhage mice treated with anti-TF antibody had significantly reduced levels of TAT (2." | ( Cedron, WJ; Cohen, MJ; Dong, W; Howard, BM; Miyazawa, BY; Ruf, W; Vilardi, RF, 2015) |
| "To explore whether, in our trauma network in a middle-income country, patients arrived at hospital soon enough after injury for tranexamic acid administration to be effective and safe." | ( Chowdhury, S; Edu, S; Navsaria, PH; Nicol, AJ; Thurston, B, 2015) |
| "The majority (74%) of bleeding trauma patients did not present within the timeframe allowed for safe administration of tranexamic therapy." | ( Chowdhury, S; Edu, S; Navsaria, PH; Nicol, AJ; Thurston, B, 2015) |
| "Excision wounds were created on the dorsum of Sprague Dawley rats and treated topically twice/day with 20 μL of PE and WE (5 mg extract/mL), 0." | ( Nafiu, AB; Rahman, MT, 2015) |
| "Histological observations revealed that wounds treated with BC-Vac epithelialized and regenerated faster than treated with BC." | ( Cui, J; Qiu, L; Qiu, Y; Wei, Q, 2016) |
| "Rapid and adequate therapy of trauma-associated coagulopathy is crucial to survival of severely injured patients." | ( Klages, M; Weber, CF; Zacharowski, K, 2016) |
| "When treated wounds were compared, no differences were found between the wound areas in adult and aged rats." | ( Carmona, EV; de Campos Peseto, D; Guedes, FR; Hummel Filho, F; Martinez, NP; Pereira, JA; Priolli, DG; Rocha, T; Silva, KC, 2016) |
| "While most acute wounds will heal with the right treatment, some get stuck along the normal healing pathway and become chronic." | ( Hampton, S, 2015) |
| "Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions." | ( Sakamoto, Y; Yahata, M, 2016) |
| "The treatment of severe trauma patients with FC during bleeding management in the first 24 h after hospital admission does not lead to higher FIB levels post-trauma beyond that occurring naturally due to the acute phase response." | ( Maegele, M; Ponschab, M; Schlimp, CJ; Schöchl, H; Treichl, B; Voelckel, W, 2016) |
| "Primarily admitted trauma patients (2012 until 2014) who were treated with TXA during the prehospital phase were matched with patients who had not received prehospital TXA, applying propensity score-based matching." | ( Böhmer, AB; Bouillon, B; Gäßler, M; Lefering, R; Ruppert, M; Wafaisade, A, 2016) |
| "Beginning in January 2011, trauma patients treated with vancomycin had trough levels (VT) monitored daily until steady state was reached." | ( Barmparas, G; Chen, E; Harada, MY; Jay, J; Ko, A; Ley, EJ; Mason, R; Mehrzadi, D; Patel, B; Sun, BJ, 2016) |
| "Of the remaining 11, five wounds showed moderate healing progression and six wounds did not respond to treatment." | ( Barrett, S; Cutting, KF; King, B, 2017) |
| "Non-healing diabetic wounds are difficult to treat." | ( Chen, D; Li, P; Li, Z; Qi, B; Shou, K; Yu, A; Zhao, Y; Zheng, X, 2017) |
| "Thirty-nine deep partial thickness wounds were created with six wounds assigned to one of six treatment groups: (i) PHMB, (ii) Ringer's solution, (iii) hypochlorous acid/sodium hypochlorite, (iv) sterile water, (v) octenidine dihydrochloride, and (vi) octenilin." | ( Davis, SC; Gil, J; Harding, A; Higa, A; Parajon, F; Solis, M; Valdes, J, 2017) |
| "In both PCL- and DBC-treated wounds, we observed a lower level of soluble collagen (compared with controls)." | ( Ciosek, J; Drobnik, J; Komisarczyk, A; Krucinska, I; Sporny, S; Szczepanowska, A, 2017) |
| "Experimental wounds produced in an in vitro porcine wound model were homogenously contaminated with bacterial suspension and treated with NPWT and different options." | ( Assadian, O; Babeluk, R; Djedovic, G; Domig, KJ; Matiasek, J, 2017) |
| "From a trauma registry (2011-2015), in which patients are prospectively included, we retrospectively retrieved the heart rate (HR), systolic blood pressure (SBP), volume of prehospital fluids and administration of noradrenaline." | ( Cesareo, E; David, JS; Decullier, E; Gueugniaud, PY; Peyrefitte, S; Tazarourte, K; Vassal, O; Voiglio, EJ, 2017) |
| "Massive traumatic haemorrhage is aggravated through the development of trauma-induced coagulopathy, which is managed by plasma transfusion and/or fibrinogen concentrate administration." | ( Ågren, A; Halmin, M; Östlund, A; Schmidt, DE; Wikman, A, 2017) |
| "In severe trauma, short-term exogenous ANP therapy during hemorrhagic shock may promote sustained endogenous expression of ANP from intestinal epithelium through activating a positive feedback loop mechanism involving phospholipase C-γ1 and reactive oxygen species crosstalk." | ( Chen, MF; Jiang, LB; Jiang, SM; Jiang, SY; Li, RJ; Liu, LL; Liu, ZZ; Shen, YH; Zeng, LL; Zhang, B; Zhang, RW; Zhao, XG, 2018) |
| "Infected wounds treated with a one-time application of the SSD-CSM-FPEG wound dressing demonstrated significantly reduced bacterial bioburden over time (99·99% of reduction by day 11; P < 0·05) compared with all the other treatment groups." | ( Christy, RJ; Davis, SC; Gil, J; Harding, A; Li, J; Natesan, S; Solis, M; Valdes, J, 2017) |
| "Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy." | ( Aristizobal, FA; Bledsoe, A; Bohannon-Worsley, LK; Borjesson, DL; Clark, KC; Davidyan, A; Gray, SN; Kol, A; LeJeune, SS; Textor, JA; Walker, NJ; Woolard, KD, 2018) |
| "Chronic wounds are among the most devastating and difficult to treat consequences of diabetes." | ( Abadir, P; Ansari, A; Berger, A; Beselman, A; Budman, J; Faghih, M; Fedarko, N; Harmon, J; Hosseini, S; Inagami, T; Keenahan, K; Lay, F; Marti, G; Rini, D; Smith, B; Tian, J; Vuong, D; Walston, J, 2018) |
| "The remaining wounds (22) showed a significant improvement after treatment with the antioxidant dressing." | ( Bastida, FD; Castro, B; López Casanova, P; Segovia, T; Soldevilla, JJ; Verdú-Soriano, J, 2017) |
| "Based on tissue cultures, wounds were treated with 100 000 units/mL of nystatin and 25 mg in 500 cc normal saline of mafenide acetate, which resulted in regression of wound infection symptoms and improvement of skin graft take." | ( Gronovich, Y; Karni-Shahroor, S; Lotan, AM; Lysy, I; Wiener-Well, Y, 2018) |
| "After anesthesia, three circular wounds (12mm diameter) were made in the animals, which were randomly separated into five treatments: Sal, saline; VO, ointment vehicles (lanolin and Vaseline); SS, positive control (silver sulfadiazine 1%); LE 5, freeze-dried extract 5%; and LE 10, lyophilized extract 10%." | ( Altoé, LS; Gonçalves, RV; Leite, JPV; Miranda, LL; Novaes, RD; Sarandy, MM; Zanuncio, VV, 2018) |
| "We created back wounds in 72 mice and treated them with or without topical curcumin (0." | ( Chen, YC; Chen, YL; Hsieh, JH; Huang, HF; Liang, CJ; Liu, CW; Pu, CM; Yen, YH, 2018) |
| " NPWT-treated wounds showed faster closure, improved macro-deformation and less local signs of infection." | ( Albert, R; Meyer-Lindenberg, A; Nolff, MC; Reese, S, 2018) |
| "Results from these assays revealed that wounds treated with MACF + O2 hydrogel dressings closed faster as compared to Derma-Gel (p<0." | ( Evancho-Chapman, MM; George, RL; Huang, H; Leipzig, ND; Li, H; Patil, PS; Shriver, LP, 2018) |
| "Further, skin wounds showed no signs of infection in those treated with Cp40." | ( Berger, N; Biglarnia, AR; Doot, RK; Foukas, PG; Gumas, JT; Hajishengallis, G; Huber-Lang, M; Kajikawa, T; Koutsogiannaki, S; Kukis, D; Lambris, JD; Mastellos, DC; Nilsson, B; Reis, ES; Resuello, RRG; Soulika, AM; Tarantal, AF; Tuplano, JV; Wang, X; Yancopoulou, D; Young, AJ, 2018) |
| "Approximately 50% of trauma patients received supplemental oxygen during the initial treatment." | ( Baekgaard, JS; Christensen, RE; Eskesen, TG; Lee, JM; Rasmussen, LS; Steinmetz, J; Velmahos, GC, 2019) |
| "Thirty-six patients with tendon-exposed wounds were treated by applying Integra or PRF (n=18 per group)." | ( Bao, Q; Cao, D; Chen, Z; Li, H; Xie, J; Zhang, S, 2019) |
| "The NCQDs were applied to treat wounds infected with MRSA and showed the same therapeutic effect as vancomycin." | ( Lin, L; Lin, X; Wang, X; Weng, S; Wu, L; Wu, W; Zhao, C; Zheng, Y, 2019) |
| "Six patients with post-traumatic impairment who were treated with systemic pentoxifylline were included." | ( Gudziol, V; Hummel, T; Whitcroft, KL, 2020) |
| "Wound healing assay was done and wounds were treated with vitamin C loaded HSA nanoparticles." | ( Armin, M; Hossini, SE; Momeni-Moghaddam, M; Omrani Bidi, J; Shojania, HR, 2019) |
| "When treating pain in the orthopaedic trauma patient opioids have classically represented the mainstay of treatment." | ( Gessner, DM; Horn, JL; Lowenberg, DW, 2020) |
| "Adults with limb trauma and pain score ≥ 4 on numerical rating scale (NRS) were randomised 1:1 to inhaled methoxyflurane 3 mL or SAT [intravenously administered (IV) morphine 0." | ( Bonafede, E; Carpinteri, G; Fabbri, A; Farina, A; Gangitano, G; Intelligente, F; Mercadante, S; Ruggiano, G; Sblendido, A; Serra, S; Soldi, A; Voza, A, 2019) |
| "Response to trauma is a complex, dynamic process in which risk can shift from bleeding to thrombosis depending on the injury pattern, hemostatic treatment, individual responses, genetic predisposition, and comorbidities." | ( Duque, P; Levy, JH; Mora, L; Schöchl, H, 2020) |
| "Four patients with chronic painful wounds were treated with topical sevoflurane (20, 20, 20 and 10 mL) following an approved therapeutic protocol in our Pain Management Unit." | ( Cortiñas-Sáenz, M; Fernández-Ginés, D; Gerónimo-Pardo, M; Selva-Sevilla, C, 2019) |
| "The effects of skin wounds on the intestinal barrier function and the beneficial effects of the dietary administration of Shewanella putrefaciens (known as SpPdp11) in gilthead seabream (Sparus aurata L." | ( Ceballos-Francisco, D; Chen, Z; Esteban, MÁ; Guardiola, FA, 2020) |
| "All patients (cases) had been treated for injuries from January 2014 to December 2016." | ( Aso, S; Doi, K; Iwagami, M; Matsui, H; Miyamoto, Y; Yasunaga, H, 2020) |
| "Chronic or senescent wounds are difficult to heal and often require a multimodal treatment plan." | ( Klein, RJ, 2020) |
| "Patients hospitalized following a traumatic injury will be frequently treated with opioids during their stay and after discharge." | ( Boulanger, A; Chauny, JM; Cournoyer, A; Daoust, R; Émond, M; Gosselin, S; Lavigne, GJ; Mac-Thiong, JM; Moore, L; Paquet, J, 2020) |
| "Transfusion therapy in hemorrhaging trauma patients is associated with the development of thromboembolic events." | ( Goslings, JC; Juffermans, NP; Schalkers, DV; Wirtz, MR, 2020) |
| "Four patients with chronic wounds that had failed multiple prior treatments were identified and treated with the BBGF technology." | ( Buck, DW, 2020) |
| "Surgical-trauma critically ill patients who received phenobarbital monotherapy, loading dose followed by a taper regimen, for the management of AWS were included in this evaluation." | ( Ammar, AA; Ammar, MA; Becher, RD; Kassab, HS; Rosen, J, 2021) |
| "The treatment of painful wounds with 5% Lidocaine Cream for 14 days resulted in reduced pain intensity, and showed high safety and tolerability." | ( Arnez, ZM; Davini, G; Dini, V; Janowska, A; Oranges, T; Papa, G; Romanelli, M; Stocco, C, 2022) |
| "The IDF Trauma Registry (IDF-TR) includes prehospital data regarding casualties treated by the IDF's medical forces." | ( Abuhasira, S; Benov, A; Chen, J; Glick, Y; Mizrachi, A; Nadler, R; Radomislensky, I; Tsur, AM; Tsur, N, 2021) |
| "Administration of TXA following traumatic injury was associated with MOF in the fibrinolysis shutdown and hyperfibrinolysis phenotypes and warrants continued evaluation." | ( Betzold, RD; Chow, JH; Fedeles, BT; Grissom, TE; Koerner, K; Kozar, RA; Morrison, JJ; Renner, C; Richards, JE; Scalea, TM; Schlee, CS; Trinh, AT, 2021) |
| "The use of whole blood (WB) to treat trauma patients is becoming more common." | ( Arbaeen, AF; Devine, DV; Schubert, P; Sheffield, WP, 2021) |
| "Silver has been used to treat infected wounds for a long time now, and the strength of the product depends on the number of Ag ions, where the greater the number of ions, the higher and faster the reactivity is." | ( Dhoonmoon, L; Staines, K; Turner-Dobbin, H, 2021) |
| "A retrospective review of trauma patients treated with packed red blood cells by high-acuity response units between January 2012 and December 2016." | ( Bodnar, D; Brown, NJ; Handy, M; Rashford, S; Stevens, Z; Williams, S, 2022) |
| "Topical antimicrobial treatment of wounds in pediatric, and especially neonatal, patients can be challenging due to increased systemic absorption, damaging inflammatory cytokines, and oxygen radicals released by bacterial death." | ( Boyar, V, 2021) |
| "Treating chronic cutaneous wounds is challenging, and debridement is a central concept in treating them." | ( Dong, J; Guan, H; Liu, Y; Lu, S; Lu, Y; Ma, X; Niu, Y; Tang, J; Xu, J; Zhang, D, 2022) |
| "Mortality related to trauma increases with age, however, there does not appear to be heterogeneity of treatment effect for TXA administration among different age groups." | ( Manoukian, MAC; Nishijima, DK; Tancredi, DJ, 2022) |
| "Using Department of Defense Trauma Registry data for the Afghanistan conflict from 2005 to 2018, we examined 2,402 records of prehospital analgesia administration to assess temporal trends in medication choice and proportions receiving analgesia, including subanalysis of a cohort screened for an indication with minimal contraindication for analgesia." | ( Burgess, M; Hinojosa-Laborde, C; Hudson, IL; Newberry, RK; Ryan, KL; Schauer, SG; Staudt, AM; VanFosson, CA, 2023) |
| "Pain control in trauma is an integral part of treatment in combat casualty care." | ( Avital, G; Bader, T; Benov, A; Chen, J; Fridrich, L; Gelikas, S; Glassberg, E; Nadler, R; Nakar, H; Sorkin, A; Tsur, AM, 2022) |
| "Identification of wounds, taking measurement photographs of the wounds before treatment, specifying the shape/sizes of foreign bodies in radiological imaging will be beneficial for determining the type of firearm, the number of shots, and the shooting distance." | ( Askay, M; Ketenci, HC; Özsoy, S, 2022) |
| "All cases of pediatric trauma in the registry were assessed for treatment with TXA." | ( Ahimor, A; Almog, O; Avital, G; Benov, A; Gelikas, S; Gendler, S; Glassberg, E; Lipsky, AM; Mozer Glassberg, Y; Nadler, R; Radomislensky, I; Talmy, T; Yazer, MH, 2023) |
| "Overall, 911 pediatric trauma patients were treated with TXA by the IDF-MC teams; the median (interquartile) age was 10 years (5-15 yr), and 72." | ( Ahimor, A; Almog, O; Avital, G; Benov, A; Gelikas, S; Gendler, S; Glassberg, E; Lipsky, AM; Mozer Glassberg, Y; Nadler, R; Radomislensky, I; Talmy, T; Yazer, MH, 2023) |
| "We randomly assigned adults with major trauma who were at risk for trauma-induced coagulopathy to receive tranexamic acid (administered intravenously as a bolus dose of 1 g before hospital admission, followed by a 1-g infusion over a period of 8 hours after arrival at the hospital) or matched placebo." | ( Bernard, SA; Burns, B; Cameron, PA; Dicker, B; Forbes, AB; Gantner, DC; Gruen, RL; Hurford, S; Maegele, M; Martin, CA; Mazur, SM; McArthur, CJ; Medcalf, RL; Mitra, B; Murray, LJ; Myles, PS; Ng, SJ; Pitt, V; Rashford, S; Reade, MC; Swain, AH; Trapani, T; Young, PJ, 2023) |
| "Among adults with major trauma and suspected trauma-induced coagulopathy who were being treated in advanced trauma systems, prehospital administration of tranexamic acid followed by an infusion over 8 hours did not result in a greater number of patients surviving with a favorable functional outcome at 6 months than placebo." | ( Bernard, SA; Burns, B; Cameron, PA; Dicker, B; Forbes, AB; Gantner, DC; Gruen, RL; Hurford, S; Maegele, M; Martin, CA; Mazur, SM; McArthur, CJ; Medcalf, RL; Mitra, B; Murray, LJ; Myles, PS; Ng, SJ; Pitt, V; Rashford, S; Reade, MC; Swain, AH; Trapani, T; Young, PJ, 2023) |