An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
| Member | Definition | Class |
|---|
| 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea | A member of the class of phenylureas that is urea which is substituted at position 1 by a 3-tert-butyl-1-methylpyrazol-5-yl group and at position 3 by a p-chlorophenyl group. | 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea |
| aurapten | A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties. | auraptene |
| azd 6244 | A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-chlorophenyl)amino, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor. | selumetinib |
| binimetinib | A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-fluorophenyl)nitrilo, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor (IC50= 12 nM). Approved by the FDA for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation in combination with encorafenib. | binimetinib |
| birb 796 | A member of the class of pyrazoles that is an immunomodulator used for treatment of rheumatoid arthritis, Crohn's disease and psoriasis. | doramapimod |
| cercosporamide | A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. | cercosporamide |
| gdc-0973 | A member of the class of N-acylazetidines obtained by selective formal condensation of the carboxy group of 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid with the secondary amino group from the azetidine ring of 3-[(2S)-piperidin-2-yl]azetidin-3-ol. An inhibitor of mitogen-activated protein kinase that is used (as its fumarate salt) in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma. | cobimetinib |
| hypothemycin | A macrolide that is isolated from the cultured broth of Hypomyces subiculosus and shows antifungal activity and inhibits the growth of some human cancer cells. | hypothemycin |
| MK-8353 | A member of the class of indazoles that is 1H-indazole substituted by a 6-(propan-2-yloxy)pyridin-3-yl group at position 3 and by a {[(3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)pyrrolidin-3-yl]carbonyl}amino group at position 5. It is a potent and selective inhibitor of ERK1 and ERK2 in vitro (IC50 values of 23.0 nM and 8.8 nM, respectively). The drug is being developed by Merck Sharp & Dohme and is currently in clinical development for the treatment of advanced/metastatic solid tumors. | MK-8353 |
| N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | A member of the class of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-4-carboxylic acid with the amino group of 3-cyanoaniline. | N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide |
| N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide | A dicarboxylic acid diamide obtained by condensation of the 3- and 4'-carboxy groups of 6-methyl[1,1'-biphenyl]-3,4'-dicarboxylic acid with cyclpropylamine and cyclpropylmethylamine respectively. | N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide |
| pamapimod | A member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis. | pamapimod |
| pd 98059 | A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'. | 2-(2-amino-3-methoxyphenyl)chromen-4-one |
| ph 797804 | A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine. | PH 797804 |
| ro5126766 | A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3. | CH5126766 |
| sb 202190 | A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta. | SB-202190 |
| sb 203580 | A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase. | SB 203580 |
| sb 220025 | Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively. | SB220025 |
| sch772984 | A member of the class of indazoles that is 1H-indazole substituted by pyridin-4-yl and {[(3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)pyrrolidin-3-yl]carbonyl}amino groups at positions 3 and 5, respectively. It is a potent inhibitor of mitogen-activated protein kinases ERK1 and ERK2 (IC50 = 4 and 1 nM, respectively) that exhibits anti-cancer properties. | SCH772984 |
| scio-469 | An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties. | talmapimod |
| trametinib | A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. | trametinib |
| u 0126 | An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties. | U0126 |
| vx-745 | A member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively | VX-745 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 22.9641 | 1 | 8 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 17.2168 | 1 | 3 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 9.5205 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 29.8950 | 1 | 16 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 15.8489 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 12.5446 | 5 | 7 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 11.3186 | 2 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 0.0135 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.2747 | 2 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.0379 | 1 | 1 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 23.2809 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 56.6072 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 67.8334 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 2.5456 | 1 | 2 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 6.4776 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 28.3356 | 1 | 6 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 7.0795 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 31.6228 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 32.4071 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 54.1956 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 34.2198 | 1 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 15.8114 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 48.5022 | 1 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 32.4071 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 46.3826 | 2 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 8.4525 | 1 | 5 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 17.8066 | 1 | 5 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 6.4219 | 1 | 7 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 10.7132 | 1 | 5 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 16.3388 | 1 | 4 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.1028 | 2 | 10 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 5.0972 | 1 | 7 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0298 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 55.7562 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 1.5849 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 25.1189 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 15.5844 | 5 | 6 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 26.6032 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 8.8218 | 9 | 14 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 13.9727 | 2 | 9 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 23.8185 | 4 | 33 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 16.7842 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 35.3485 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 6.4219 | 1 | 7 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.1028 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 10.9649 | 3 | 5 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 1.3333 | 1 | 1 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 13.1311 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 27.4269 | 1 | 5 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 1.5089 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 16.4816 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 17.5381 | 2 | 19 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 15.7775 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 42.0104 | 2 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 6.4219 | 1 | 7 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 6.4219 | 1 | 14 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.6778 | 3 | 14 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 3.0670 | 2 | 2 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 14.3989 | 1 | 4 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 25.3090 | 4 | 7 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 23.5077 | 2 | 11 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 17.1785 | 3 | 8 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 11.2202 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 5.0119 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 2.3109 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 0.0196 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 7.3078 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 19.3512 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 20.9370 | 3 | 5 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 23.1379 | 3 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 14.2745 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 11.0328 | 3 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 20.7185 | 2 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 36.0415 | 1 | 2 |
| PINK1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| polyprotein | Zika virus | Potency | 35.3485 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 16.5311 | 1 | 2 |
| PPM1D protein | Homo sapiens (human) | Potency | 16.8000 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 23.7101 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 12.5893 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 10.7196 | 2 | 3 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 2.0596 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 9.0598 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 17.4552 | 3 | 5 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 14.4578 | 2 | 2 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 16.7175 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 16.7175 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 11.9860 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 12.9177 | 1 | 5 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 22.0899 | 2 | 23 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 0.5623 | 1 | 1 |
| Thrombopoietin | Homo sapiens (human) | Potency | 16.0105 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 17.7517 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 16.9398 | 4 | 10 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 19.4693 | 1 | 6 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 930.9235 | 2 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 55.3026 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Actin-related protein 3 | Homo sapiens (human) | IC50 | 0.0530 | 1 | 1 |
| Activin receptor type-1B | Homo sapiens (human) | IC50 | 44.0000 | 1 | 1 |
| Acyl carrier protein, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 2.9500 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 1.7210 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 6.0680 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 3.4070 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 8.5470 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 4.8310 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 20.4040 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 20.2360 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 8.5470 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8310 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 8.5470 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.8310 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 34.1670 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 12.8130 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 31.8860 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 14.5570 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Mus musculus (house mouse) | IC50 | 0.3000 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 1.0173 | 5 | 15 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 0.0100 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 7.7562 | 4 | 4 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | IC50 | 0.5250 | 2 | 2 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 345.1000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Bromodomain testis-specific protein | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 2.9500 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 35.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 35.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 35.0000 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Casein kinase 1, delta tv1 | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 0.3580 | 4 | 4 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 11.4760 | 1 | 1 |
| Chain A, Erk2 | Homo sapiens (human) | Ki | 0.0004 | 1 | 1 |
| Chain A, Extracellular Regulated Kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 9.0095 | 1 | 4 |
| Chain A, MAP KINASE P38 | Homo sapiens (human) | IC50 | 9.0095 | 1 | 2 |
| Chain A, Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.0058 | 1 | 2 |
| Chain A, PROTEIN (MAP KINASE P38) | Homo sapiens (human) | IC50 | 9.0095 | 1 | 6 |
| Cholesteryl ester transfer protein | Homo sapiens (human) | IC50 | 0.0400 | 1 | 1 |
| Chymotrypsinogen B | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Citron Rho-interacting kinase | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Complex I intermediate-associated protein 30, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 15.3850 | 2 | 2 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 17.1540 | 5 | 5 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 21.8667 | 3 | 3 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 15.1100 | 2 | 2 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 16.6500 | 4 | 4 |
| Cyclin-G-associated kinase | Homo sapiens (human) | IC50 | 0.4133 | 3 | 3 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 15.1100 | 2 | 2 |
| Cytochrome c oxidase subunit NDUFA4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 20.2500 | 4 | 4 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 19.9500 | 4 | 4 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 4.2500 | 2 | 2 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 11.0676 | 8 | 8 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 20.2500 | 4 | 4 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 1,358.5923 | 8 | 10 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Death-associated protein kinase 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.0200 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | IC50 | 0.2708 | 4 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 4.6519 | 38 | 41 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Rattus norvegicus (Norway rat) | IC50 | 4.2000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | IC50 | 4.2103 | 19 | 21 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 4.2000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | IC50 | 0.6300 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | IC50 | 0.1600 | 1 | 1 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | IC50 | 1.1000 | 2 | 2 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | IC50 | 0.0700 | 1 | 1 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | IC50 | 0.0900 | 1 | 1 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | IC50 | 2.9867 | 3 | 3 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | IC50 | 9.4000 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 35.5600 | 5 | 5 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | IC50 | 24.0000 | 1 | 1 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 19.5038 | 5 | 6 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Heat shock protein beta-1 | Homo sapiens (human) | IC50 | 0.0555 | 1 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | IC50 | 0.5800 | 2 | 2 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 25.0000 | 2 | 2 |
| Insulin receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Insulin receptor-related protein | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 17.5000 | 2 | 2 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 4.8700 | 1 | 1 |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | IC50 | 36.7200 | 5 | 5 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | IC50 | 25.0000 | 2 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Malate dehydrogenase | Thermus thermophilus | IC50 | 100.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | IC50 | 17.5000 | 2 | 2 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | IC50 | 43.3333 | 3 | 3 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0430 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0380 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | IC50 | 15.5000 | 2 | 2 |
| Melatonin receptor type 1A | Homo sapiens (human) | Ki | 1.9000 | 1 | 1 |
| Misshapen-like kinase 1 | Homo sapiens (human) | IC50 | 0.0400 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 2.0041 | 17 | 18 |
| Mitogen-activated protein kinase 1 | Rattus norvegicus (Norway rat) | IC50 | 254.5168 | 1 | 4 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 5.7200 | 8 | 9 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Ki | 2.0825 | 2 | 4 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 0.4595 | 41 | 46 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 0.0712 | 4 | 4 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 0.2001 | 31 | 33 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 0.1862 | 29 | 31 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Ki | 0.0008 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 8.2751 | 123 | 159 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 0.2469 | 15 | 23 |
| Mitogen-activated protein kinase 14 | Mus musculus (house mouse) | IC50 | 0.0493 | 2 | 7 |
| Mitogen-activated protein kinase 2 | Pneumocystis carinii | IC50 | 0.1050 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 5.5634 | 8 | 9 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | IC50 | 11.6050 | 4 | 4 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 24.6530 | 15 | 17 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Ki | 400.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | IC50 | 0.4665 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0008 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 10.6660 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 2.5690 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | Ki | 2.0450 | 1 | 2 |
| Myotonin-protein kinase | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4L | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 16.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 2.0450 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 16.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 2.0450 | 1 | 2 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 0.0250 | 1 | 1 |
| NT-3 growth factor receptor | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Nuclear receptor subfamily 2 group C member 2 | Homo sapiens (human) | IC50 | 0.0300 | 1 | 1 |
| P2X purinoceptor 7 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| P2X purinoceptor 7 | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 3.6000 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 23.9000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 6.0000 | 3 | 4 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 5.4000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 26.7550 | 4 | 4 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 24.5100 | 5 | 5 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 38.4500 | 2 | 2 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 36.9333 | 3 | 3 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Protein kinase C-like 1 | Candida albicans | IC50 | 0.0440 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | IC50 | 4.3000 | 3 | 3 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase LCK | Mus musculus (house mouse) | Ki | 5.4000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 0.5150 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 11.5000 | 4 | 4 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 45.0000 | 2 | 2 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 17.5000 | 2 | 2 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.9120 | 11 | 11 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 19.4480 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | IC50 | 27.5000 | 2 | 2 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 2.0319 | 8 | 9 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | IC50 | 17.5000 | 2 | 2 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 0.2271 | 6 | 6 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | IC50 | 43.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | IC50 | 15.5000 | 2 | 2 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 14.3667 | 3 | 3 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 27.5000 | 2 | 2 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Sgk1 | Homo sapiens (human) | IC50 | 31.5000 | 2 | 2 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase WNK2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 8.0980 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 6.4340 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 20.4040 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 20.2360 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0100 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 5.5000 | 2 | 2 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 29.0000 | 1 | 1 |
| Tau-tubulin kinase 1 | Homo sapiens (human) | IC50 | 47.2000 | 1 | 1 |
| Tau-tubulin kinase 2 | Homo sapiens (human) | IC50 | 9.3400 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | IC50 | 18.0000 | 2 | 2 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | IC50 | 0.4650 | 2 | 2 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 0.4940 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | IC50 | 4.0000 | 2 | 3 |
| Tyrosinase | Mus musculus (house mouse) | IC50 | 0.0320 | 1 | 2 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 21.0000 | 2 | 2 |
| Tyrosine-protein kinase ABL1 | Mus musculus (house mouse) | IC50 | 14.6000 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | IC50 | 15.5000 | 2 | 2 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | IC50 | 15.5000 | 2 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | IC50 | 8.5000 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 18.7500 | 4 | 4 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | IC50 | 10.3500 | 2 | 2 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 65.0000 | 2 | 2 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 65.0000 | 2 | 2 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 13.3643 | 7 | 7 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Ki | 5.4000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | IC50 | 0.9600 | 1 | 1 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 18.3333 | 3 | 3 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 8.9000 | 1 | 1 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 18.3333 | 3 | 3 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 0.6250 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 8.4467 | 3 | 3 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 25.0007 | 1 | 6 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 25.0060 | 1 | 6 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 20.5882 | 3 | 17 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 19.2324 | 3 | 17 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 19.6750 | 3 | 16 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 6.6723 | 3 | 9 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 7.7500 | 2 | 8 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 17.4186 | 3 | 15 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | EC50 | 0.3855 | 1 | 2 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 18.1875 | 4 | 16 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 7.6375 | 2 | 8 |
| Aurora kinase A | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Aurora kinase B | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Aurora kinase C | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 7.6425 | 2 | 8 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 17.4416 | 3 | 15 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 22.1182 | 2 | 11 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 3.4000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 7.7125 | 1 | 4 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 19.4812 | 3 | 16 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 18.7020 | 3 | 15 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 21.8250 | 2 | 11 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 6.9125 | 2 | 8 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 17.3422 | 3 | 15 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 13.7637 | 6 | 19 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 20.5882 | 3 | 17 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 17.5205 | 3 | 15 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 10.0000 | 1 | 4 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Chain A, p38 MAP kinase | Homo sapiens (human) | Kd | 0.5801 | 1 | 4 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 16.3700 | 3 | 15 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 21.9182 | 2 | 11 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 12.2222 | 3 | 9 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 7.5500 | 2 | 8 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 18.8733 | 3 | 15 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 7.5550 | 2 | 8 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 20.0000 | 2 | 8 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 17.1494 | 4 | 16 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 15.3568 | 5 | 19 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 3 | 12 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 9 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 14.8291 | 6 | 19 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 7.6932 | 5 | 17 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 7.6792 | 5 | 17 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 17.6923 | 3 | 13 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 19.3996 | 2 | 11 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 16.6667 | 3 | 12 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 18.5714 | 3 | 14 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 12.8692 | 4 | 13 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 12.2222 | 3 | 9 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 18.1643 | 3 | 14 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 16.9176 | 4 | 17 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 6.9267 | 3 | 9 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 17.0412 | 4 | 17 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 16.2353 | 4 | 17 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 4.3367 | 3 | 9 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 15.1386 | 4 | 14 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 6.3780 | 3 | 10 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 7.1800 | 3 | 10 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 17.3550 | 4 | 16 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 18.1875 | 4 | 16 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 22.7583 | 2 | 12 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 7.8329 | 24 | 98 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 14.2392 | 5 | 18 |
| Eukaryotic peptide chain release factor GTP-binding subunit ERF3B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 19.2875 | 3 | 16 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 10.0000 | 4 | 16 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 19.6375 | 3 | 16 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 18.5062 | 3 | 16 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 17.1160 | 5 | 25 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 15.1979 | 4 | 14 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Insulin receptor | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 7.8500 | 2 | 8 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 10.0000 | 1 | 4 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 7.6750 | 2 | 8 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 17.3346 | 3 | 15 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 9.5375 | 2 | 8 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 7.1444 | 3 | 9 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 7.5929 | 16 | 72 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 20.0344 | 2 | 9 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 17.0588 | 5 | 17 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 11.4567 | 7 | 21 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | EC50 | 1.9927 | 1 | 3 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 7.1720 | 9 | 27 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | EC50 | 1.9927 | 1 | 3 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 3.4204 | 7 | 17 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | EC50 | 1.9927 | 1 | 3 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 3.4209 | 4 | 9 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | EC50 | 1.5095 | 2 | 4 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 3.3776 | 25 | 52 |
| Mitogen-activated protein kinase 14 | Mus musculus (house mouse) | Kd | 0.2000 | 4 | 6 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 19.1250 | 3 | 16 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 10.4778 | 3 | 9 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 14.1253 | 6 | 19 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 13.0757 | 7 | 23 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 20.5882 | 3 | 17 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 18.1575 | 3 | 16 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 7.5375 | 1 | 4 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 18.5714 | 3 | 14 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 17.1720 | 3 | 15 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 7.9750 | 2 | 8 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 4 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 16.9474 | 4 | 19 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 7.5475 | 2 | 8 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 18.5714 | 3 | 14 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 5 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 8.1500 | 1 | 4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 10.0000 | 12 | 48 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 7.6500 | 2 | 8 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 15.9335 | 4 | 17 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 18.5714 | 3 | 14 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 18.1320 | 3 | 15 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 18.2421 | 4 | 19 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 13.7962 | 7 | 32 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 17.7988 | 4 | 17 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 6.7325 | 2 | 8 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 8.7000 | 1 | 4 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 16.0249 | 4 | 18 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 11.9261 | 14 | 57 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 23.8462 | 2 | 13 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 14.8178 | 5 | 23 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 10.0000 | 4 | 16 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 18.8412 | 4 | 17 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 16.0060 | 6 | 25 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 17.2000 | 5 | 25 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 14.8161 | 5 | 23 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 22.0000 | 2 | 10 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 24.9454 | 1 | 7 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 16.8769 | 4 | 16 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 17.6923 | 3 | 13 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 18.5714 | 3 | 14 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 7.8250 | 1 | 4 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 7.3875 | 2 | 8 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 5.3682 | 4 | 11 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 16.6667 | 2 | 6 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 15.4545 | 3 | 11 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 11.8829 | 5 | 23 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 22.0000 | 2 | 10 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 20.5882 | 3 | 17 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 8.9625 | 2 | 8 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 18.7467 | 3 | 15 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 16.7613 | 3 | 15 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 14.1415 | 3 | 13 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 15.4545 | 3 | 11 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 15.1343 | 5 | 18 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 16.6667 | 3 | 12 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 15.4545 | 3 | 11 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 17.6923 | 3 | 13 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 15.4545 | 3 | 11 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 22.1727 | 2 | 11 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 21.1111 | 3 | 18 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 8.3750 | 2 | 8 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 22.0000 | 2 | 10 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 12 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 22.7273 | 2 | 11 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 15.0345 | 4 | 17 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 25.8103 | 1 | 7 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 26.2956 | 1 | 8 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 25.7441 | 1 | 7 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 8 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 18.9467 | 3 | 15 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 18.9750 | 3 | 16 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 15.0016 | 4 | 19 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 8.7250 | 1 | 4 |
| Tumor necrosis factor | Homo sapiens (human) | EC50 | 0.0180 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 8.6176 | 31 | 118 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 16.5825 | 4 | 16 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 5.9450 | 2 | 8 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 14.1385 | 4 | 13 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 13.1760 | 5 | 20 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 18.2800 | 3 | 15 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 18.7500 | 4 | 16 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 17.3684 | 4 | 19 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 15.4545 | 3 | 11 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 14.7118 | 4 | 17 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 17.2533 | 3 | 15 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 10.8222 | 3 | 9 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 7.5021 | 2 | 8 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 19.3333 | 3 | 15 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 8.6250 | 2 | 8 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 16.6000 | 4 | 16 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 10.0000 | 2 | 8 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 4 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 6 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 26.3509 | 1 | 8 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 7.6025 | 2 | 8 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 7.8889 | 3 | 9 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 8.5222 | 3 | 9 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 7 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 16 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 4 |