An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
| Member | Definition | Class |
|---|
| (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside | A lignan that is (+)-lyoniresinol substituted by a beta-D-glucopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from the root barks of Stemmadenia minima and Lycium chinense, it exhibits antimicrobial activities. | (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside |
| 1-nonanol | A nonanol that is nonane substituted by a hydroxy group at position 1. It has been isolated as a component of volatile oils from plants like Hordeum vulgare. | nonan-1-ol |
| 1-octanol | An octanol carrying the hydroxy group at position 1. | octan-1-ol |
| 1-phenazinecarboxylic acid | An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group. | phenazine-1-carboxylic acid |
| 2-hexyloxybenzamide | An benzamide that is salicylamide in which the phenolic hydroxy group has been converted into the corresponding hexyl ether. It has been used as a topical antifungal agent. | exalamide |
| 2-methyl-4-isothiazolin-3-one | A 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom. It is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM). | methylisothiazolinone |
| 2-octenal | The (E)-isomer of oct-2-enal. | (E)-oct-2-enal |
| 2,4-diacetylphloroglucinol | A benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups. | 2,4-diacetylphloroglucinol |
| 2,5-dimethylfuran | A member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by methyl groups. | 2,5-dimethylfuran |
| 2',4',6'-trihydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2', 4' and 6' respectively. | pinocembrin chalcone |
| 3-phenylpropionic acid | A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group. | 3-phenylpropionic acid |
| 3'-deoxyadenosine 5'-triphosphate | | cordycepin triphosphate |
| 5-hydroxybenzofuran-2-one | A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a hydroxy group at position 5. | 5-hydroxybenzofuran-2-one |
| 6-methoxybenzoxazolinone | A 2-benzoxazolinone that is substituted by a methoxy group at position 6. | 6-methoxy-2-benzoxazolinone; Coixol |
| 6-tuliposide b | A 6-O-acyl-D-glucose in which the 6-acyl group is specified as (3S)-3,4-dihydroxy-2-methylidenebutanoyl. A secondary metabolite with potent antibacterial activity, occurring specifically in tulip anthers. | 6-tuliposide B |
| acetopyrrothine | A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and acetamido groups, respectively. It is a potent inhibitor of RNA polymerases, inhibits the angiogenesis of human umbilical vein endothelial cells, and also inhibits JAMM metalloproteases. | thiolutin |
| acrylonitrile | A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an ethenyl group. | acrylonitrile |
| actinodaphine | An organic heteropentacyclic compound 6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline bering additional hydroxy and methoxy substituents at positions 10 and 11 respectively. | actinodaphnine |
| albicanol | A drimane-type sesquiterpenoid orginally isolated from the liverwort Diplophyllum albicans. It exhibits fish antifeedant, antifungal and antineoplastic activities. | (+)-albicanol |
| altenusin | A carboxybiphenyl that is [biphenyl]-2-carboxylic acid which is substituted by a hydroxy group at positions 3, 4' and 5', methoxy group at position 5 and a methyl group at position 2'. It is a a metabolite isolated from Alternaria and several other fungal species. | altenusin |
| alternariol monomethyl ether | A benzochromenone that is alternariol in which the hydroxy group at position 9 has been converted into the corresponding methyl ether. A natural product found in Chaetomium globosum as well as being one of the two most important compounds belonging to the group of Altenaria mycotoxins. | djalonensone |
| antimycin a | A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. | antimycin A |
| arjunolic acid | A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). Isolated from Symplocos lancifolia and Juglans sinensis, it exhibits antioxidant and antimicrobial activities. | arjunolic acid |
| ascochlorin | A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (1E,3E)-3-methyl-1-[(1R,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl]penta-1,3-dien-5-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by several fungi including Ascochyta viciae . It exhibits anticancer, antifungal and antiprotozoal activities. | ascochlorin |
| asukamycin | A polyketide that is a member of the manumycin family of antibiotics and exhibits strong antibacterial, antifungal, and antineoplastic activities. Isolated from from the actinomycete bacterium Streptomyces nodosus subsp. asukaensis. | asukamycin |
| aureothin | A C-nitro compound that is (3Z)-3-[(2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ylidene]tetrahydrofuran which is substituted by a 6-methoxy-3,5-dimethyl-4-oxo-4H-pyran-2-yl group at position 5. It is isolated from the soil bacterium, Streptomyces thioluteus and exhibits antitumor, antifungal, and insecticidal activities. | aureothin |
| australifungin | A carbobicyclic compound that is 4a,5,6,7,8,8a-hexahydronaphthalen-1(4H)-one substituted by hydroxy groups at positions 2, 5 and 8, a (2Z)-3-hydroxyprop-2-enoyl group at position 4, methyl groups at positions 4 and 7 and a 2R-octan-2-yl group at position 3 (the 4S,4aR,5S,7R,8R,8aS stereoisomer). It is isolated from the fermentation extracts of Sporormiella australis and exhibits antifungal activity by interfering with the fungal lipid metabolism. | australifungin |
| azaserine | A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species. | azaserine |
| baicalein | A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. | baicalein |
| beauvericin | A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues. | beauvericin |
| benzethonium chloride | A (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses. | benzethonium chloride |
| beta-thujaplicin | A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities. | beta-thujaplicin |
| borrelidin | A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties. | borrelidin |
| bromophycolide a | A diterpenoid that is a macrolide isolated from the Fijian red alga Callophycus serratus. It has been found to exhibit moderate cytotoxicity against several human tumour cell lines via specific apotopic cell death. It also displays anti-HIV, antibacterial, antifungal and antimalarial activity. | bromophycolide A |
| callipeltin a | A 10-membered cyclodepsipeptide containing four amino acids in the L- configuration, Ala, Leu, Thr (2 residues); one (Arg) in the D-configuration; two N-methyl amino acids, N-MeAla and N-MeGln; a methoxy tyrosine, a 3, 4-dimethyl-L-glutamine, and a 4-amino-7-guanidino-2,3 dihydroxypentanoic acid (AGDHE), formally derived from L-Arg. It is obtained from the shallow water sponge Callipelta and has been found to show activity against HIV virus. | callipeltin A |
| capsidiol | An eremophilane sesquiterpenoid that is (+)-5-epi-aristolochene bearing additional 1beta- and 3alpha-hydroxy substituents. It is a phytoalexin produced in Nicotiana and Capsicum plant species in response to pathogen attack. | capsidiol |
| cercosporamide | A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. | cercosporamide |
| cerulenin | An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function. | cerulenin |
| chaetoviridin a | An azaphilone that is 6H-furo[2,3-h]isochromene-6,8(6aH)-dione substituted by a chloro group at position 5, a 3-hydroxy-2-methylbutanoyl group at position 9, a methyl group at position 6a and a 3-methylpent-1-en-1yl group at position 3. Isolated from Chaetomium globosum, it exhibits natifungal activity against plant pathogenic fungi. | chaetoviridin A |
| ci 940 | A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17. | leptomycin B |
| cinnamaldehyde | The E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes. | (E)-cinnamaldehyde |
| citronellal | A monoterpenoid, the main component of citronella oil which gives it its distinctive lemon aroma. | citronellal |
| clioquinol | A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease. | 5-chloro-7-iodoquinolin-8-ol |
| concanamycin a | A concanamycin in which the lactone ring contains 4 double bonds and is substituted by 4 methyl groups, 2 hydroxy groups, 2 methoxy groups and an ethyl group. | concanamycin A |
| coniferaldehyde | A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. | coniferyl aldehyde |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| cyclosporine | A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. | cyclosporin A |
| cystothiazole a | An organonitrogen heterocyclic antibiotic that is 2,4'-bi-1,3-thiazole substituted by an isopropyl group at position 2' and a 3,5,7-trimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl group at position 4 (the 2E,4R,5S,6E stereoisomer). It is isolated from the culture broth of myxobacterium, Cystobacter fuscus, and exhibits antifungal and cytotoxic activity. | cystothiazole A |
| decanaldehyde | A saturated fatty aldehyde formally arising from reduction of the carboxy group of capric acid (decanoic acid). | decanal |
| decaprenoic acid | A polyunsaturated fatty acid that is octa-2,6-dienoic acid bearing two methyl substituents at positions 3 and 7 (the 2E-isomer). | geranic acid |
| dehydrotomatine | A steroid alkaloid that consists of tomatine which has undergone formal dehydrogenation across positions 5 and 6. Found in tomatoes. | 5,6-dehydrotomatine |
| dequalinium | A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group. | dequalinium |
| dequalinium chloride | An organic chloride salt that is the dichloride salt of dequalinium. | dequalinium chloride |
| diallyl disulfide | An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium. | diallyl disulfide |
| dichlorvos | An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate. | dichlorvos |
| diethylstilbestrol | An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. | diethylstilbestrol |
| dihydrosanguinarine | A benzophenanthridine alkaloid obtained by selective hydrogenation of the 13,14-position of sanguinarine. | dihydrosanguinarine |
| dihydroxyacetone | A ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. | dihydroxyacetone |
| dioncophylline a | An isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 7-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 4,5-dimethoxy-2-methylnaphthalen-1-yl group. It is a naphthylisoquinoline alkaloid isolated from the roots and stem barks of Triphyophyllum peltatum and exhibits antifungal, antimalarial, antineoplastic and molluscicidal activites. | 7-epi-dioncophylline A; dioncophylline A |
| dioscin | A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage. | dioscin |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| elaiophylin | A macrodiolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes. | elaiophylin |
| enfumafungin | A triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. and which specifically inhibits glucan synthesis in fungal cells. | enfumafungin |
| ergosta-7,22-dien-3-ol, (3beta,5alpha,6alpha,22e)-isomer | A 3beta-sterol consisting of an ergostane skeleton with double bonds at 7- and 22-positions. | 5alpha-ergosta-7,22-dien-3beta-ol |
| ethyl-p-hydroxybenzoate | An ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol, | ethylparaben |
| eugeniin | An ellagitannin isolated from the dried flower buds of Eugenia caryophyllata. It exhibits alpha-glucosidase inhibitory activity and antiviral activity against acyclovir and phosphonoacetic acid (PAA)-resistant herpes simplex virus type 1 (HSV-1) as well as the wild-type HSV-1. | eugeniin |
| ferrostatin-1 | An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. | ferrostatin-1 |
| fr 900848 | A polyketide that is 5'-amino-5'-deoxy-3,4,5,6-tetrahydrouridine in which one of the hydrogens of the amino group is substituted by a (1E,3E)-1-[(1R,1'R,1''R,1'''R,2S,2'R,2''R,2'''S)-2'''-{(E)-2-[(1R,2R)-2-methylcyclopropyl]ethenyl}[1,1':2',1'':2'',1'''-quater(cyclopropan)]-2-yl]-5-oxopenta-1,3-dien-5-yl group. It is a metabolite isolated from the bacterium, Streptoverticillium fervens and targets the catalytic subunit of the fungal UDP-glycosyltransferase, the first step in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. It exhibits broad spectrum antifungal activity against several pathogenic fungi including Mucorales. | jawsamycin |
| gentian violet | An iminium ion that is malachite green cation in which the hydrogen at the para- psition of the monosubstituted phenyl group is replaced by a dimethylamino group. | crystal violet cation |
| gentian violet | An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain. | crystal violet |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| gliotoxin | A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi. | gliotoxin |
| heptachlor | A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1H-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations. | heptachlor |
| hypothemycin | A macrolide that is isolated from the cultured broth of Hypomyces subiculosus and shows antifungal activity and inhibits the growth of some human cancer cells. | hypothemycin |
| hypothiocyanite ion | A sulfur oxoacid that is sulfenic acid in which the hydrogen attached to the sulfur has been replaced by a cyano group. | hypothiocyanous acid |
| isoalantolactone | A sesquiterpene lactone of the eudesmanolide group. It has been isolated from Inula helenium. | isoalantolactone |
| isopentyl alcohol | An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group. | isoamylol |
| isovanillin | A member of the class of benzaldehydes that is 4-methoxybenzaldehyde substituted by a hydroxy group at position 3. It is an inhibitor of aldehyde oxidase. | isovanillin |
| jasplakinolide | A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer. | jaspamide |
| kaempferol-3-o-galactoside | A beta-D-galactoside compound with a 4',5,7-trihydroxychromen-3-yl group at the anomeric position. | kaempferol 3-O-beta-D-galactoside |
| l 683590 | A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties. | ascomycin |
| lariciresinol | A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer). | (+)-lariciresinol |
| liriodenine | An oxoaporphine alkaloid that is 4,5,6,6a-tetradehydronoraporphin-7-one substituted by a methylenedioxy group across positions 1 and 2. It is isolated from Annona glabra and has been shown to exhibit antimicrobial and cytotoxic activities. | liriodenine |
| lubimin | A vetispirane sesquiterpenoid that consists of (2R,5S,6S,8S,10R)-8-hydroxy-10-methyl-2-(prop-1-en-2-yl)spiro[4.5]decane bearing a formyl substituent at position 6. | lubimin |
| methyl parathion | A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4. | parathion-methyl |
| methylamphotericin b | The methyl ester of amphotericin B. | amphotericin B methyl ester |
| methylparaben | A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. | methylparaben |
| mevastatin | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. | mevastatin |
| miltefosine | A phospholipid that is the hexadecyl monoester of phosphocholine. | miltefosine |
| monensin | A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. | monensin A |
| monorden | An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90). | radicicol |
| mucidin | An enoate ester that is the methyl ester of (2E,3Z,5E)-2-(methoxymethylene)-3-methyl-6-phenylhexa-3,5-dienoic acid. | mucidin |
| naled | An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use within the European Union. | naled |
| nikkomycin | A uridine-based nucleoside-peptide antibiotic which inhibits fungal chitin biosynthesis by inhibiting chitin synthase. | nikkomycin Z |
| nitroxoline | A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5. | nitroxoline |
| osthenol | A hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. | osthenol |
| oxolinic acid | A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. | oxolinic acid |
| pallidol | A tetracyclic stilbenoid that is a homodimer obtained by cyclodimerisation of resveratrol. | pallidol |
| pentamidine | A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. | pentamidine |
| pf 1163a | A macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a (2R)-2-hydroxypentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. | PF 1163A |
| pf 1163b | A macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a pentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. | PF 1163B |
| phleomycin d1 | A glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. | phleomycin D1 |
| physcione | A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources. | physcion |
| piperonylic acid | A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. | piperonylic acid |
| piperyline | A N-acylpyrrolidine that is pyrollidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum. | piperyline |
| propargyl alcohol | A terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1. | prop-2-yn-1-ol |
| propylparaben | The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive. | propylparaben |
| pyoluteorin | A member of the class of resorcinols that is resorcinol in which the hydrogen at position 2 is replaced by a 4,5-dichloro-1H-pyrrole-2-carbonyl group. It is a natural product found in Pseudomonas fluorescens which exhibits antibacterial properties and is a strong inducer of caspase-3-dependent apoptosis. | pyoluteorin |
| salicylic acid | A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. | salicylic acid |
| sampangine | A copyrine alkaloid with formula C15H8N2O, extracted from several plants including the stem bark of Cananga odorata. It is a heme biosynthesis inhibitor and exhibits antifungal and anticancer properties. | sampangine |
| sclareol | A labdane diterpenoid that is labd-14-ene substituted by hydroxy groups at positions 8 and 13. It has been isolated from Salvia sclarea. | sclareol |
| sinapaldehyde | A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5. | (E)-sinapaldehyde |
| sinefungin | An adenosine that is the the delta-(5'-adenosyl) derivative of ornithine. | sinefungin |
| sodium arsenite | An inoganic sodium salt with formula with formula NaAsO2. | sodium arsenite |
| solasodine | An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills. | solasodine |
| sordaricin | A tetracyclic diterpenoid that is produced by several fungi including Sordaria araneosa. | sordaricin |
| sporothriolide | A furofuran that is (3aR,6aR)-hexahydrofuro[3,4-b]furan substituted by an oxo group at positions 2 and 4, methylene group at position 3 and by an hexyl group at position 6. It is a metabolite isolated from several species of fungi. | sporothriolide |
| strobilurin b | An enoate ester that is the methyl ester of (2E,3Z,5E)-6-(4-chloro-3-methoxyphenyl)-2-(methoxymethylene)-3-methylhexa-3,5-dienoic acid. | strobilurin B |
| surfactin A | A cyclodepsipeptide that is N-[(3R)-3-hydroxy-11-methyldodecanoyl]-L-alpha-glutamyl-L-leucyl-D-leucyl-L-valyl-L-alpha-aspartyl-D-leucyl-L-leucine in which the C-terminal carboxy group has been lactonised by condensation with the alcoholic hydroxy group. | surfactin A |
| surfactin c | A cyclodepsipeptide that is N-[(3R)-3-hydroxy-13-methyltetradecanoyl]-L-alpha-glutamyl-L-leucyl-D-leucyl-L-valyl-L-alpha-aspartyl-D-leucyl-L-leucine in which the C-terminal carboxy group has been lactonised by condensation with the alcoholic hydroxy group. | surfactin C |
| tavaborole | A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails). | tavaborole |
| thermozymocidin | An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. | myriocin |
| tolfenpyrad | An aromatic amide obtained by formal condensation of the carboxy group of 4-chloro-3-ethyl-1-methylpyrazole-5-carboxylic acid with the amino group of 1-[4-(4-methylphenoxy)phenyl]methylamine. | tolfenpyrad |
| tomatine | A steroid alkaloid that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose. | tomatine |
| undecanoic acid | A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series. | undecanoic acid |
| usnic acid | A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b. | usnic acid |
| veratraldehyde | A dimethoxybenzene that is benzaldehyde substituted by methoxy groups at positions 3 and 4. It is found in peppermint, ginger, raspberry, and other fruits. | veratraldehyde |
| wighteone | A member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 6. It has been isolated from Ficus mucuso. | wighteone |
| zwittermicin a | The (+)-enantiomer of zwittermicin A. It is a water-soluble natural antibiotic from the fermentation of the soil-borne bacterium Bacillus cereus and shows significant activity against phytopathogenic fungi. | (+)-zwittermicin A |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 19.0394 | 1 | 16 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 18.6890 | 1 | 14 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 11.2207 | 2 | 23 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 43.5739 | 4 | 41 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 35.2403 | 2 | 24 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 21.9303 | 1 | 37 |
| alpha synuclein, partial | Homo sapiens (human) | Potency | 0.1515 | 1 | 1 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 33.4703 | 3 | 3 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 15.5106 | 1 | 15 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 28.9003 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 25.9996 | 12 | 210 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.8118 | 3 | 33 |
| arylsulfatase A | Homo sapiens (human) | Potency | 13.3448 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 18.4132 | 4 | 19 |
| Ataxin-2 | Homo sapiens (human) | Potency | 20.4122 | 2 | 19 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 13.2638 | 5 | 10 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 24.9867 | 2 | 24 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 26.1216 | 1 | 1 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa] | Homo sapiens (human) | Potency | 0.1500 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 11.8410 | 2 | 4 |
| BRCA1 | Homo sapiens (human) | Potency | 10.8820 | 1 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 28.2512 | 1 | 7 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 3.7939 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 33.7827 | 1 | 6 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 29.0000 | 1 | 6 |
| caspase-3 | Homo sapiens (human) | Potency | 33.7827 | 1 | 6 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 29.0000 | 1 | 6 |
| Caspase-7 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 33.5387 | 3 | 63 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 18.0776 | 2 | 19 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 20.7534 | 1 | 25 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 23.4526 | 4 | 10 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 23.2240 | 2 | 10 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 23.4824 | 2 | 11 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 28.0789 | 2 | 11 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 15.7132 | 2 | 19 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 42.5913 | 1 | 8 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 17.8216 | 3 | 25 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 17.2802 | 3 | 14 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 14.0700 | 1 | 25 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 15.7132 | 2 | 19 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 58.1866 | 2 | 11 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 2.2409 | 1 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 2.0304 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.8341 | 1 | 11 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 19.8707 | 1 | 12 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 15.7278 | 1 | 7 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 14.0117 | 2 | 46 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 16.6148 | 2 | 15 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 28.6366 | 1 | 32 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 13.0286 | 3 | 3 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 17.4872 | 1 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 7.8660 | 1 | 5 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 28.2912 | 1 | 6 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 25.4222 | 2 | 4 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 24.8515 | 1 | 4 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 28.2963 | 2 | 4 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 4.7444 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 64.2328 | 2 | 17 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 24.2709 | 1 | 12 |
| endonuclease IV | Escherichia coli | Potency | 11.0344 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 12.6028 | 1 | 2 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 12.6028 | 1 | 2 |
| enteropeptidase precursor | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 26.5984 | 12 | 262 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 34.3378 | 3 | 38 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 25.9965 | 9 | 141 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 13.2935 | 1 | 22 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 7.8090 | 4 | 19 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 53.0065 | 2 | 2 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 38.5655 | 5 | 54 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Potency | 44.6684 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 43.4654 | 2 | 13 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 12.0465 | 1 | 6 |
| G | Vesicular stomatitis virus | Potency | 15.8341 | 1 | 11 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| GALC protein | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 14.1197 | 1 | 24 |
| geminin | Homo sapiens (human) | Potency | 12.2842 | 4 | 40 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 19.2638 | 3 | 64 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 11.5015 | 1 | 7 |
| GLS protein | Homo sapiens (human) | Potency | 19.2497 | 2 | 8 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 26.3960 | 6 | 16 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 28.0959 | 5 | 64 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 35.4305 | 2 | 22 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Potency | 0.1515 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 18.7108 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 39.7757 | 2 | 6 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 28.7968 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 29.7071 | 2 | 34 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 35.7168 | 2 | 2 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 7.2102 | 2 | 33 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 9.4697 | 1 | 8 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 22.8594 | 2 | 11 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 68.9151 | 2 | 23 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 22.9313 | 1 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.8341 | 1 | 11 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 11.9287 | 3 | 12 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 13.3165 | 4 | 10 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 38.3706 | 2 | 32 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 15.9954 | 3 | 18 |
| IDH1 | Homo sapiens (human) | Potency | 13.8207 | 1 | 9 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 56.8352 | 2 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.8341 | 1 | 22 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 8.6780 | 1 | 7 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 23.3814 | 1 | 8 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 23.3814 | 1 | 8 |
| Interferon beta | Homo sapiens (human) | Potency | 15.4639 | 3 | 37 |
| interleukin 8 | Homo sapiens (human) | Potency | 59.3978 | 1 | 9 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 8.5722 | 1 | 17 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 9.3894 | 1 | 10 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | Potency | 0.1800 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 30.4241 | 4 | 25 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 15.9010 | 3 | 6 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 27.6778 | 1 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 23.9525 | 1 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 15.8633 | 3 | 37 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.8448 | 2 | 14 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 1.3449 | 2 | 3 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 25.9982 | 1 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.2687 | 1 | 5 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 5.4587 | 1 | 10 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 64.7801 | 1 | 3 |
| Nrf2 | Homo sapiens (human) | Potency | 26.9926 | 2 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 31.9622 | 4 | 80 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 11.8238 | 2 | 11 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 27.4566 | 1 | 9 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 34.2368 | 2 | 21 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 27.6079 | 1 | 8 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 14.1793 | 2 | 54 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 8.6523 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 32.1800 | 3 | 68 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| P53 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 98.7258 | 1 | 6 |
| Parkin | Homo sapiens (human) | Potency | 13.3267 | 3 | 5 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 28.8578 | 1 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 14.8162 | 2 | 14 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 33.8078 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 29.7616 | 5 | 77 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 32.4820 | 5 | 41 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 26.8419 | 1 | 15 |
| PINK1 | Homo sapiens (human) | Potency | 14.0187 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 6.9780 | 1 | 8 |
| polyprotein | Zika virus | Potency | 12.0465 | 1 | 6 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 11.9550 | 1 | 8 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 9.1526 | 1 | 12 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 16.1280 | 1 | 11 |
| PPM1D protein | Homo sapiens (human) | Potency | 14.9556 | 1 | 16 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 38.9680 | 3 | 40 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 33.7680 | 1 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.7737 | 2 | 25 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 11.9133 | 5 | 7 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 12.8072 | 4 | 6 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 17.0674 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 26.9914 | 2 | 54 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 82.3993 | 1 | 2 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 32.4493 | 1 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 32.3276 | 3 | 70 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.4581 | 4 | 59 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 39.8107 | 1 | 2 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 15.4026 | 3 | 6 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 18.9022 | 1 | 3 |
| shiga toxin 1 B subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| shiga toxin 1 variant A subunit | Escherichia coli O157:H7 | Potency | 10.0238 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 89.1251 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 41.2240 | 2 | 17 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 41.2240 | 2 | 17 |
| Smad3 | Homo sapiens (human) | Potency | 20.2618 | 1 | 13 |
| snurportin-1 | Homo sapiens (human) | Potency | 56.8352 | 2 | 4 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 17.2194 | 1 | 7 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 16.9510 | 1 | 18 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 22.0564 | 1 | 8 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.2336 | 2 | 91 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 40.5852 | 1 | 7 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 29.3584 | 3 | 15 |
| Thrombopoietin | Homo sapiens (human) | Potency | 4.0871 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 22.2098 | 3 | 63 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 33.8897 | 8 | 28 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 27.1275 | 7 | 56 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 21.0462 | 2 | 8 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| TSHR protein | Homo sapiens (human) | Potency | 30.1313 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 42.1632 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 12.9707 | 3 | 7 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 6.9780 | 1 | 8 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 6.9780 | 1 | 8 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 62.6084 | 2 | 17 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 21.5751 | 2 | 35 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.9848 | 5 | 36 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 33.2782 | 1 | 18 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 37.0877 | 1 | 21 |
| Vpr | Human immunodeficiency virus 1 | Potency | 3.1623 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 5.3233 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 235.9333 | 3 | 3 |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | Homo sapiens (human) | IC50 | 77.8000 | 1 | 1 |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | Homo sapiens (human) | IC50 | 153.9000 | 2 | 2 |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | Homo sapiens (human) | IC50 | 77.8000 | 1 | 1 |
| [Tau protein] kinase | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 5.9775 | 2 | 4 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 2.2000 | 1 | 1 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 54.0000 | 4 | 8 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 77.4200 | 3 | 5 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 1.7300 | 1 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | IC50 | 0.0483 | 4 | 4 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | IC50 | 0.1340 | 9 | 9 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 12,800.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 2.2962 | 1 | 4 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.6562 | 1 | 4 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 3.1400 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 1.9980 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 18.3747 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 9.6247 | 1 | 3 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 18.3747 | 1 | 3 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 9.6247 | 1 | 3 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 12.8920 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 5.9860 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 350.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 3 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 54.0000 | 4 | 8 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 77.4200 | 3 | 5 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Acetolactate synthase catalytic subunit, mitochondrial | Saccharomyces cerevisiae S288C | IC50 | 0.2000 | 1 | 1 |
| Acetylcholinesterase | Anopheles gambiae (African malaria mosquito) | IC50 | 0.1920 | 2 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 82.5950 | 6 | 6 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 55.2580 | 8 | 10 |
| Acrosin | Sus scrofa (pig) | Ki | 2.3000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 2.8560 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 1.6660 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 6.1890 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 3.4745 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 3.1870 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.8015 | 1 | 2 |
| Albumin | Homo sapiens (human) | Ki | 5,888,440,000.0000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 7.7300 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 2.2637 | 1 | 3 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.2453 | 1 | 3 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.2785 | 3 | 4 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.8015 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.2785 | 3 | 4 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.8015 | 1 | 2 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 6.4030 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.3700 | 2 | 2 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 3.1470 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 4.7850 | 1 | 4 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 1.7942 | 1 | 4 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 4.5330 | 1 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 2.0693 | 1 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 6.3320 | 1 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.9200 | 1 | 3 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 56.7400 | 3 | 3 |
| Amiloride-sensitive amine oxidase [copper-containing] | Homo sapiens (human) | Ki | 0.2900 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 2.2076 | 7 | 7 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 0.4850 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 16.9300 | 4 | 4 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 21.5000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 15.5000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 15.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 12.5825 | 33 | 33 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 153.7590 | 2 | 5 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 3.7130 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 133.9575 | 3 | 4 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 6.4846 | 1 | 2 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 61.7500 | 2 | 2 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 92.6052 | 2 | 6 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 4 | 4 |
| ATP-dependent molecular chaperone HSC82 | Saccharomyces cerevisiae S288C | IC50 | 0.2000 | 1 | 1 |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | IC50 | 0.1192 | 3 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 3.9290 | 42 | 43 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 2.7500 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 1.7183 | 6 | 6 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 3.5750 | 2 | 2 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 51.6150 | 3 | 4 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 7.7510 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 22.0880 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 12.7550 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 282.0333 | 3 | 3 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 6.8400 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.7575 | 4 | 4 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 151.2118 | 8 | 17 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 500.3000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | Ki | 0.3000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 20.3000 | 1 | 1 |
| BRCA1-associated RING domain protein 1 | Homo sapiens (human) | IC50 | 3.8900 | 1 | 1 |
| Breast cancer type 1 susceptibility protein | Homo sapiens (human) | IC50 | 3.8900 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 12.7656 | 6 | 6 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 0.9800 | 2 | 2 |
| C-terminal-binding protein 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Calcineurin subunit B type 1 | Homo sapiens (human) | IC50 | 34.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 61.1212 | 5 | 8 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | Ki | 11.2700 | 3 | 3 |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | Ki | 5.9800 | 2 | 2 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0002 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 324.0000 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 0.0890 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ki | 0.0720 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 247.6667 | 2 | 3 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 145.9268 | 7 | 20 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 142.1575 | 3 | 16 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 165.9500 | 2 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 144.8688 | 3 | 16 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 4.7650 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 287.6667 | 2 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 144.1307 | 8 | 21 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 224.3786 | 2 | 14 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 161.9571 | 2 | 14 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 209.5929 | 2 | 14 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 186.5214 | 2 | 14 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 305.8800 | 3 | 15 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 146.7425 | 3 | 16 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 142.7882 | 4 | 17 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | IC50 | 3.2700 | 1 | 1 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | Ki | 0.5200 | 1 | 1 |
| Carboxypeptidase A1 | Bos taurus (cattle) | IC50 | 2.7600 | 1 | 1 |
| Casein kinase 1, delta tv1 | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 4.0400 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 46.7000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 46.7000 | 1 | 1 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | IC50 | 12.3694 | 1 | 2 |
| Cathepsin B | Homo sapiens (human) | Ki | 155.2333 | 6 | 6 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 2.3600 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Cell division protein FtsZ | Escherichia coli K-12 | IC50 | 6.3350 | 2 | 2 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Chain A, Ermc' Methyltransferase | Bacillus subtilis | Ki | 18.0000 | 1 | 1 |
| Chain A, Ermc' Rrna Methyltransferase | Bacillus subtilis | Ki | 18.0000 | 1 | 1 |
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | IC50 | 35.0600 | 1 | 1 |
| Chain B, Cathepsin B | Homo sapiens (human) | Ki | 154.4000 | 1 | 1 |
| Chitin synthase 1 | Candida albicans | IC50 | 3.2000 | 2 | 2 |
| Chitin synthase 1 | Saccharomyces cerevisiae S288C | IC50 | 0.0002 | 2 | 2 |
| Cholinesterase | Equus caballus (horse) | IC50 | 106.9827 | 3 | 3 |
| Cholinesterase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
| Collagenase ColG | Hathewaya histolytica | IC50 | 24.0000 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 25.0000 | 4 | 4 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 0.7700 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 503.2650 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 0.7700 | 1 | 1 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 0.2200 | 1 | 1 |
| Cystathionine gamma-lyase | Homo sapiens (human) | IC50 | 56.1750 | 3 | 4 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 28.8750 | 2 | 2 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 17.7450 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | Ki | 8.8720 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 1.2200 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 85.0000 | 4 | 5 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.2600 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 66.4000 | 4 | 5 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 65.4667 | 5 | 6 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 51.4892 | 6 | 7 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 31.8420 | 10 | 12 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 6.0550 | 2 | 4 |
| Cytochrome P450 3A43 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A43 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A5 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| Cytochrome P450 3A7 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A7 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| D | Rattus norvegicus (Norway rat) | IC50 | 75.0000 | 1 | 1 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 1.0700 | 2 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 5.4325 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 2.7165 | 1 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 8.2495 | 1 | 2 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 59.0000 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 2.7495 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 4.5417 | 1 | 3 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.5423 | 1 | 3 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| delta-type opioid receptor | Homo sapiens (human) | IC50 | 17.3590 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.9580 | 1 | 1 |
| Deoxyribonuclease-1 | Homo sapiens (human) | IC50 | 0.3500 | 1 | 1 |
| Diamine acetyltransferase 1 | Homo sapiens (human) | Ki | 2.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 10.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase (fumarate) | Saccharomyces cerevisiae S288C | IC50 | 10.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 25.6500 | 2 | 2 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 46.5300 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase Mdm2 isoform a | Homo sapiens (human) | IC50 | 3.5800 | 1 | 1 |
| E3 ubiquitin-protein ligase RNF31 | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.4730 | 1 | 1 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 0.1312 | 6 | 6 |
| Estrogen receptor | Homo sapiens (human) | Ki | 0.0002 | 5 | 5 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 0.1588 | 4 | 4 |
| Estrogen receptor beta | Homo sapiens (human) | Ki | 0.0003 | 3 | 3 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Exportin-1 | Homo sapiens (human) | IC50 | 0.0760 | 2 | 2 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 79.0000 | 2 | 2 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 13.5533 | 3 | 3 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 61.3000 | 1 | 1 |
| fMet-Leu-Phe receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 28.2000 | 1 | 1 |
| G-protein coupled receptor 84 | Homo sapiens (human) | Ki | 0.1080 | 1 | 1 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 6.5300 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 5.6234 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 1,325.0000 | 2 | 2 |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 14.8000 | 2 | 2 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 4.8180 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 22.1000 | 1 | 2 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 24.7350 | 3 | 6 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Glycine N-methyltransferase | Homo sapiens (human) | IC50 | 316.0000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 102.7645 | 1 | 2 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 9.9710 | 3 | 3 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 0.0660 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | IC50 | 0.2092 | 5 | 5 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 0.1148 | 6 | 6 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 12.5893 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 1.1550 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 1.1360 | 1 | 1 |
| Histidine kinase | Caulobacter vibrioides | IC50 | 184.0000 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 21.9167 | 6 | 6 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 26.6450 | 2 | 2 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 48.8427 | 2 | 2 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 74.1000 | 3 | 16 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 2.5000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 66.7667 | 5 | 18 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 2.5000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 32.5790 | 2 | 2 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 74.1188 | 3 | 16 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 135.5575 | 4 | 4 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 91.0883 | 6 | 6 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 2.5000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | IC50 | 0.2600 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 33.7100 | 1 | 1 |
| hypothetical protein SA1422 | Staphylococcus aureus subsp. aureus N315 | IC50 | 42.9000 | 2 | 2 |
| Ileal sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 24.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Indolethylamine N-methyltransferase | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Insulin receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1190 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 6.0800 | 6 | 6 |
| Interleukin-2 | Mus musculus (house mouse) | IC50 | 0.0050 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 18.7000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 3.0515 | 1 | 2 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 1.2205 | 1 | 2 |
| kappa-type opioid receptor isoform 1 | Homo sapiens (human) | IC50 | 18.8950 | 2 | 2 |
| KiSS-1 receptor | Homo sapiens (human) | Ki | 3.6000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 0.0050 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 13.9100 | 1 | 1 |
| Leucine--tRNA ligase, cytoplasmic | Saccharomyces cerevisiae S288C | IC50 | 2.1000 | 1 | 1 |
| Leucine--tRNA ligase, cytoplasmic | Saccharomyces cerevisiae S288C | Ki | 16.6250 | 2 | 2 |
| Linoleate 9S-lipoxygenase-4 | Glycine max (soybean) | IC50 | 22.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 4.3300 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 11.0500 | 2 | 2 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| M-phase inducer phosphatase 1 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0430 | 1 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0380 | 1 | 1 |
| Mcl-1 | Homo sapiens (human) | IC50 | 4.1476 | 1 | 1 |
| Methionine aminopeptidase 1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 0.8467 | 3 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 43.9980 | 5 | 5 |
| Mitochondrial succinate dehydrogenase subunit C | Zymoseptoria tritici | IC50 | 15.0010 | 2 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 2.1160 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 32.9030 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | IC50 | 0.0330 | 1 | 1 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| mRNA cap guanine-N7 methyltransferase | Homo sapiens (human) | IC50 | 0.0335 | 3 | 3 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 3.9615 | 1 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 1.6080 | 1 | 2 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 1.7033 | 3 | 3 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 6.5500 | 2 | 2 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 3.5082 | 10 | 10 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 5 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 5.5593 | 1 | 3 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 1.3390 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.1430 | 1 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.4063 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 7.7150 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 1.6353 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.9473 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.1320 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 1.1847 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 0.8510 | 1 | 3 |
| Mycothiol S-conjugate amidase | Mycobacterium tuberculosis H37Rv | IC50 | 50.0000 | 1 | 1 |
| N-acylethanolamine-hydrolyzing acid amidase | Rattus norvegicus (Norway rat) | IC50 | 4.1000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 24.2000 | 1 | 1 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 700.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 600.0000 | 2 | 2 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | Mus musculus (house mouse) | IC50 | 2.2000 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 6.2000 | 1 | 1 |
| Nicotinamide N-methyltransferase | Homo sapiens (human) | IC50 | 39.2367 | 3 | 3 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0002 | 1 | 1 |
| Non-structural protein 1 | Dengue virus | IC50 | 0.0410 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 4.7230 | 1 | 1 |
| NS5 | Zika virus | IC50 | 1.4000 | 2 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | IC50 | 14.6000 | 1 | 1 |
| Nuclear receptor subfamily 2 group C member 2 | Homo sapiens (human) | IC50 | 0.0300 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 7.9150 | 1 | 2 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 6.4846 | 1 | 2 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 100.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase A | Homo sapiens (human) | IC50 | 0.0252 | 12 | 12 |
| Peptidyl-prolyl cis-trans isomerase A | Homo sapiens (human) | Ki | 0.0645 | 8 | 8 |
| Peptidyl-prolyl cis-trans isomerase B | Homo sapiens (human) | IC50 | 0.0088 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase D | Homo sapiens (human) | IC50 | 0.0036 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase D | Homo sapiens (human) | Ki | 0.0129 | 4 | 4 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | IC50 | 0.0021 | 2 | 2 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | Homo sapiens (human) | Ki | 0.0060 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP4 | Homo sapiens (human) | IC50 | 4.0080 | 1 | 2 |
| Peptidylglycine alpha-amidating monooxygenase | Rattus norvegicus (Norway rat) | Ki | 0.0060 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 6.2885 | 1 | 2 |
| perilipin-5 | Homo sapiens (human) | IC50 | 5.6665 | 1 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Mus musculus (house mouse) | IC50 | 0.5700 | 1 | 1 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 6.1000 | 1 | 2 |
| Plasminogen | Homo sapiens (human) | IC50 | 28.4000 | 3 | 5 |
| Platelet-activating factor receptor | Cavia porcellus (domestic guinea pig) | IC50 | 200.0000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 78.8133 | 2 | 15 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 175.5856 | 8 | 9 |
| Polyphenol oxidase 2 | Agaricus bisporus | Ki | 0.0600 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 41.5700 | 3 | 5 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 53.3333 | 3 | 3 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | IC50 | 31.5320 | 2 | 5 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Ki | 1.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 33.1800 | 2 | 5 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 2.9630 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 51.0929 | 3 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 1 | 1 |
| Potassium channel subfamily K member 9 | Homo sapiens (human) | IC50 | 159.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 27.2217 | 4 | 6 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 6.4846 | 1 | 2 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 2,300.0000 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 1.8000 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 131.9200 | 5 | 5 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 79.4175 | 3 | 4 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2.1000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 75.8684 | 7 | 9 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 2.5000 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 54.3333 | 3 | 3 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 295.3000 | 2 | 2 |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | IC50 | 40.5500 | 2 | 2 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | IC50 | 32.7000 | 3 | 3 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 1.0100 | 2 | 2 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 0.3250 | 2 | 2 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 5.8000 | 1 | 1 |
| Protein kinase C-like 1 | Candida albicans | IC50 | 0.0440 | 1 | 1 |
| protein Mdm4 isoform 1 | Homo sapiens (human) | IC50 | 3.5800 | 1 | 1 |
| Protein S100-B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 1 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 2 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 3 | Homo sapiens (human) | IC50 | 35.8333 | 3 | 3 |
| Protein-L-isoaspartate(D-aspartate) O-methyltransferase | Homo sapiens (human) | Ki | 86.5000 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Rattus norvegicus (Norway rat) | IC50 | 0.1800 | 1 | 1 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 22.6400 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 9.6000 | 1 | 1 |
| RanBP-type and C3HC4-type zinc finger-containing protein 1 | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 2.0840 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase S | Homo sapiens (human) | IC50 | 10.3000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 6.8900 | 2 | 3 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 2.9424 | 24 | 32 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 8.3672 | 3 | 8 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 0.4550 | 1 | 1 |
| RNA guanine-N7 methyltransferase activating subunit | Homo sapiens (human) | IC50 | 0.3190 | 1 | 2 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 11.6872 | 1 | 1 |
| RNA-directed RNA polymerase | | IC50 | 8.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 26.3333 | 3 | 3 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | Ki | 8.6000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 22.6000 | 1 | 1 |
| sentrin-specific protease 1 | Homo sapiens (human) | IC50 | 19.3000 | 2 | 2 |
| Serine palmitoyltransferase 2 | Homo sapiens (human) | IC50 | 0.0001 | 1 | 1 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 8.1000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 9.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 314.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 0.1830 | 1 | 1 |
| Sharpin | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 130.0000 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 1 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 1 | Rattus norvegicus (Norway rat) | Ki | 0.2210 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 2 | Rattus norvegicus (Norway rat) | Ki | 0.2210 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 3 | Homo sapiens (human) | IC50 | 1.6500 | 2 | 2 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | Ki | 0.1805 | 2 | 2 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 31.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 2.4160 | 1 | 4 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 1.9198 | 1 | 4 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 2.2637 | 1 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.2453 | 1 | 3 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 7.4650 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 3.9660 | 1 | 2 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Sodium/glucose cotransporter 1 | Homo sapiens (human) | IC50 | 25.4000 | 1 | 1 |
| Sodium/glucose cotransporter 2 | Homo sapiens (human) | IC50 | 33.3000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 22.1000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 43.8258 | 1 | 2 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 9.5000 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 280.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 144.7720 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 670.5000 | 2 | 2 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 1,020.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.9500 | 5 | 5 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.8276 | 5 | 5 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 3.3867 | 6 | 6 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | Ki | 36.0000 | 1 | 1 |
| Sortase A | Streptococcus mutans | IC50 | 10.2000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | IC50 | 5.6000 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 4.3240 | 1 | 4 |
| Substance-K receptor | Homo sapiens (human) | Ki | 1.4415 | 1 | 4 |
| Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | Zymoseptoria tritici | IC50 | 15.0010 | 2 | 2 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 43.5000 | 2 | 2 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 156.0000 | 2 | 2 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 1.1600 | 1 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 97.6100 | 2 | 2 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | IC50 | 0.0300 | 1 | 1 |
| Thermolysin | Bacillus thermoproteolyticus | IC50 | 61.0000 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 185.0000 | 1 | 1 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 132.0000 | 1 | 1 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 57.3333 | 1 | 3 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 4.3590 | 1 | 1 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | IC50 | 32.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0132 | 1 | 1 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 8.3620 | 1 | 1 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 10.0933 | 2 | 3 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 0.8800 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 5.4590 | 1 | 2 |
| Transcriptional activator Myb | Gallus gallus (chicken) | IC50 | 19.2304 | 1 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | Ki | 0.0026 | 1 | 1 |
| tRNA (cytosine(38)-C(5))-methyltransferase | Homo sapiens (human) | IC50 | 13.2000 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 33.4250 | 2 | 4 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 3.7000 | 1 | 1 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 3.7000 | 1 | 1 |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | IC50 | 25.6000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 7.6533 | 3 | 3 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 5.7163 | 1 | 3 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Ki | 19,400.0000 | 1 | 1 |
| Tyrosine-protein phosphatase YopH | Yersinia pseudotuberculosis IP 32953 | Ki | 1,000.0000 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Ubiquitin-like domain-containing CTD phosphatase 1 | Homo sapiens (human) | IC50 | 66,000.0000 | 1 | 1 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 37.5070 | 1 | 2 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 160.3000 | 3 | 8 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 82.5780 | 5 | 5 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 82.5780 | 5 | 5 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 25.9250 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | Ki | 10.4010 | 1 | 1 |
| Vif | Human immunodeficiency virus 1 | IC50 | 46.5300 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 37.4000 | 2 | 2 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 34.2633 | 2 | 3 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 100,000.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | Ki | 93.8800 | 1 | 1 |