An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21).
ChEBI ID: 63158
| Member | Definition | Class |
|---|---|---|
| malonyl coenzyme a | The S-malonyl derivative of coenzyme A. | malonyl-CoA |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 290 (25.15) | 18.7374 |
| 1990's | 237 (20.56) | 18.2507 |
| 2000's | 327 (28.36) | 29.6817 |
| 2010's | 229 (19.86) | 24.3611 |
| 2020's | 70 (6.07) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 7 (0.60%) | 5.53% |
| Reviews | 97 (8.30%) | 6.00% |
| Case Studies | 20 (1.71%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,045 (89.39%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Carnitine O-palmitoyltransferase 1, muscle isoform | Rattus norvegicus (Norway rat) | IC50 | 1.2000 | 1 | 1 |