A substance used to destroy rodent pests.
ChEBI ID: 33288
| Member | Definition | Class |
|---|---|---|
| ethanethiol | An alkanethiol that is ethane substituted by a thiol group at position 1. It is added to odorless gaseous products such as liquefied petroleum gas (LPG) to provide a garlic scent which helps warn of gas leaks. | ethanethiol |
| lead arsenate | An inorganic lead salt composed from lead(2+) and arsenate dianion. It was widely used in the United States in the 1950's as an insecticide to control pests in fruit orchards, specifically apples and cherries. | lead arsenate |
| scilliroside | A beta-D-glucoside that is scillirosidin in which the hydroxy group at position 3 is substituted by a beta-D-glucopyranoside group. It is a rodenticide extracted from the bulb of the Mediterranean squill plant and was used for the control of Norway rats, black rats, house mice, long-tailed field mice, and field voles. | scilliroside |
| sodium arsenite | An inoganic sodium salt with formula with formula NaAsO2. | sodium arsenite |
| strychnine | A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. | strychnine |
| thallium sulfate | A metal sulfate in which the counterion is thallium and the ratio of thallium to sulfate is 2:1. It is a rodenticide used to control rats, squirrels, mice, moles, prairie dogs, ants and cockroaches. It is no longer registered for pesticide use in the United States. | thallium sulfate |
| undecan-2-one | A dialkyl ketone with methyl and nonyl as the two alkyl groups. | undecan-2-one |
| vitamin d 2 | A vitamin D supplement and has been isolated from alfalfa. | vitamin D2 |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 4,298 (48.15) | 18.7374 |
| 1990's | 1,144 (12.82) | 18.2507 |
| 2000's | 1,490 (16.69) | 29.6817 |
| 2010's | 1,682 (18.84) | 24.3611 |
| 2020's | 313 (3.51) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 331 (3.44%) | 5.53% |
| Reviews | 397 (4.12%) | 6.00% |
| Case Studies | 297 (3.09%) | 4.05% |
| Observational | 11 (0.11%) | 0.25% |
| Other | 8,589 (89.24%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 18.6231 | 2 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 5.3538 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 19.7347 | 2 | 2 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 44.6684 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 34.5000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 45.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 34.5000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 45.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 75.8000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 0.1843 | 14 | 20 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | Ki | 0.0503 | 3 | 3 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.0120 | 1 | 1 |
| Glycine receptor subunit beta | Homo sapiens (human) | IC50 | 0.2871 | 6 | 9 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 94.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Taste receptor type 2 member 10 | Homo sapiens (human) | EC50 | 22.5000 | 2 | 2 |
| Taste receptor type 2 member 46 | Homo sapiens (human) | EC50 | 0.6900 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | Kb | 69.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-2 | Homo sapiens (human) | Kb | 69.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | Homo sapiens (human) | Kb | 69.0000 | 1 | 1 |
| Taste receptor type 2 member 10 | Homo sapiens (human) | Activity | 1.5500 | 2 | 2 |
| Vitamin D3 receptor | Homo sapiens (human) | Activity | 1,254.0000 | 2 | 2 |