A substance used to destroy pests of the subclass Acari (mites and ticks).
| Member | Definition | Class |
|---|
| 2-methyl-5-(1-methylethenyl)cyclohexanol | A p-menthane monoterpenoid that is the dihydro derivative of carveol. | dihydrocarveol |
| 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | A pyrrole resulting from the N-dealkylation of the ethoxymethyl group of chlorfenapyr. It is the active insecticide of the proinsecticide chlorfenapyr. | tralopyril |
| acephate | A phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. | acephate |
| acequinocyl | An acetate ester consisting of 1,4-naphthoquinone bearing acetoxy and dodecyl substituents at positions 2 and 3 respectively. | acequinocyl |
| aminocarb | A carbamate ester that is phenyl methylcarbamate substituted by a dimethylamino group at position 4 and a methyl group at position 3. | aminocarb |
| amitraz | A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5. | amitraz |
| azinphos ethyl | | azinphos-ethyl |
| benomyl | A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. | benomyl |
| benzyl benzoate | A benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol. It has been isolated from the plant species of the genus Polyalthia. | benzyl benzoate |
| bifenazate | A carboxylic ester obtained by formal condensation of 2-(4-methoxy[1,1'-biphenyl]-3-yl)hydrazinecarboxylic acid with 2-propanol. | bifenazate |
| carbaryl | A carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid. | carbaryl |
| carbofuran | | carbofuran |
| chlorpyrifos | An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. | chlorpyrifos |
| chlorpyrifos-methyl | An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. | chlorpyrifos-methyl |
| coumaphos | | coumaphos |
| demeton-s-methyl | | demeton-S-methyl |
| diazinon | A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4. | diazinon |
| dibutylaminosulfenylcarbofuran | | carbosulfan |
| dichlofluanid | A member of the class of sulfamides that is sulfamide in which the hydrogens attached to one of the nitrogens are replaced by methyl groups, while those attached to the other nitrogen are replaced by a phenyl and a [dichloro(fluoro)methyl]sulfanediyl group. A fungicide introduced in 1965 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union. | dichlofluanid |
| dicrotophos | | dicrotophos |
| dimethoate | A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group. | dimethoate |
| dimethoxon | | omethoate |
| disulfoton | An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate. | disulfoton |
| endosulfan | A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10. | endosulfan |
| ethion | An organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7). | ethion |
| ethyl oleate | A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol. | ethyl oleate |
| fenamiphos | | fenamiphos |
| fenazaquin | | fenazaquin |
| fenitrothion | An organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4. | fenitrothion |
| fenthion | An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities. | fenthion |
| fluazuron | An N-acylurea that is urea in which one of the hydrogens has been replaced by a 3,6-difluorobenzoyl group, while a hydrogen attached to the other nitrogen has been replaced by a 4-chloro-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl group. It is used to control ticks in cattle. | fluazuron |
| formetanate | | formetanate |
| heptenophos | | heptenophos |
| hexachlorophene | An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union. | hexachlorophene |
| mecarbam | An organic thiophosphate that is O,O-diethyl hydrogen phosphorodithioate in which the hydrogen attached to a sulfur is replaced by a 2-[(ethoxycarbonyl)(methyl)amino]-2-oxoethyl group. | mecarbam |
| methamidophos | An organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate. | methamidophos |
| methidathion | | methidathion |
| methiocarb | A carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid. | methiocarb |
| methomyl | A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime. | methomyl |
| methyl parathion | A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4. | parathion-methyl |
| metolcarb | | metolcarb |
| monocrotophos | An alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate. | monocrotophos |
| naled | An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use within the European Union. | naled |
| naphthazarin | A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. | naphthazarin |
| parathion | | parathion |
| phenthoate, (+-)-isomer | An organic thiophosphate that is ethyl mandelate in which the hydroxy group has been replaced by a (dimethoxyphosphorothioyl)sulfanediyl group. | phenthoate |
| phenylphosphonothioic acid, 2-ethyl 2-(4-nitrophenyl) ester | | EPN |
| phorate | | phorate |
| phosalone | A member of the class of 1,3-benzoxazoles carrying a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2 and a chloro group at position 6. It is an organothiophosphate insecticide. | phosalone |
| phosmet | | phosmet |
| pirimiphos methyl | An organic thiophosphate that is O,O-dimethyl O-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2. | pirimiphos-methyl |
| profenofos | | profenofos |
| propoxur | A carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group. | propoxur |
| quinalphos | | quinalphos |
| sulfluramid | A sulfonamide obtained by the formal condensation of perfluorooctane-1-sulfonic acid with ethylamine. | sulfluramid |
| sulfotepp | | sulfotep |
| temefos | An organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group. | temephos |
| tetrachlorvinphos | | tetrachlorvinphos |
| thiometon | | thiometon |
| triazophos | | triazophos |
| usnic acid | A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b. | usnic acid |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 25.6323 | 1 | 5 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 25.4818 | 1 | 3 |
| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase | Arabidopsis thaliana (thale cress) | Potency | 84.0575 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 5.5299 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 34.3998 | 4 | 166 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 43.7102 | 2 | 20 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 30.4829 | 1 | 17 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 6.7740 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 22.3872 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 32.9298 | 12 | 227 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 27.4963 | 3 | 87 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 3.6626 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 31.3822 | 1 | 10 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 34.7779 | 2 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 35.7657 | 2 | 12 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 50.1187 | 1 | 3 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 50.5407 | 1 | 3 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 63.6514 | 1 | 5 |
| caspase-3 | Homo sapiens (human) | Potency | 50.5407 | 1 | 3 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 63.6514 | 1 | 5 |
| Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 39.1257 | 3 | 53 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 18.9156 | 2 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 16.0992 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 42.2090 | 2 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 26.7449 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 28.4535 | 1 | 6 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 26.4005 | 2 | 12 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 61.0212 | 1 | 9 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 17.0590 | 1 | 6 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 19.9054 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 40.3620 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 26.4005 | 2 | 12 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 76.2052 | 1 | 10 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 4.7725 | 1 | 9 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 18.7052 | 1 | 8 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.0331 | 2 | 28 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.1396 | 2 | 14 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 39.9995 | 1 | 31 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 27.8710 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| enteropeptidase precursor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.7141 | 12 | 212 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 41.8326 | 2 | 40 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 32.4608 | 9 | 188 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 17.9078 | 1 | 6 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 0.0042 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 37.5929 | 5 | 46 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 4.7725 | 1 | 9 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| galactokinase | Homo sapiens (human) | Potency | 30.4625 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.0331 | 1 | 14 |
| geminin | Homo sapiens (human) | Potency | 11.6600 | 2 | 15 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 26.5194 | 3 | 88 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 13.6848 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 33.5514 | 5 | 50 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 44.5576 | 1 | 19 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 3.0783 | 1 | 3 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 25.3513 | 1 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 36.9684 | 2 | 32 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 14.9763 | 1 | 4 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 31.4159 | 1 | 9 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 18.8953 | 2 | 13 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 82.3346 | 2 | 33 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 4.7725 | 1 | 9 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 10.7362 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 44.0972 | 2 | 26 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 50.1187 | 1 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 5.8048 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 24.5900 | 2 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 4.7725 | 1 | 18 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 15.8139 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 15.8139 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 9.3357 | 2 | 11 |
| interleukin 8 | Homo sapiens (human) | Potency | 60.3188 | 1 | 3 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 6.0721 | 2 | 7 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 17.8569 | 1 | 3 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 47.2034 | 3 | 37 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 26.6173 | 2 | 8 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 15.9252 | 1 | 5 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 25.7877 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 36.7274 | 4 | 100 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 19.7128 | 1 | 4 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 29.5156 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 43.9060 | 2 | 21 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 27.7899 | 1 | 5 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 12.8926 | 2 | 15 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 7.8117 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.7152 | 3 | 147 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 14.9388 | 1 | 4 |
| Parkin | Homo sapiens (human) | Potency | 21.3145 | 1 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 94.5626 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 5.3956 | 1 | 5 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 39.5869 | 5 | 52 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 42.2395 | 1 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 30.4335 | 5 | 44 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 39.8107 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 35.2346 | 1 | 11 |
| PINK1 | Homo sapiens (human) | Potency | 21.3145 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.9433 | 1 | 1 |
| polyprotein | Zika virus | Potency | 56.2341 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 32.4681 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.9763 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 27.6710 | 1 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 39.3053 | 3 | 71 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 37.0137 | 1 | 11 |
| progesterone receptor | Homo sapiens (human) | Potency | 30.7781 | 2 | 48 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 27.5472 | 1 | 5 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 28.7224 | 2 | 74 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 44.9647 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 34.8359 | 3 | 98 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 25.7619 | 4 | 84 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 24.5554 | 1 | 5 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 26.8198 | 2 | 19 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 26.8198 | 2 | 19 |
| Smad3 | Homo sapiens (human) | Potency | 20.5523 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 24.5900 | 2 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 9.6037 | 2 | 5 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 21.2503 | 1 | 4 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 11.0957 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 19.6266 | 2 | 28 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 35.4813 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 44.0936 | 3 | 67 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 27.0740 | 8 | 22 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 31.9531 | 7 | 89 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 26.5968 | 2 | 8 |
| TSHR protein | Homo sapiens (human) | Potency | 2.1331 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 10.2538 | 3 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.9433 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.9433 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 57.8405 | 2 | 9 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 34.5318 | 2 | 52 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 29.3000 | 5 | 43 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 47.0826 | 1 | 22 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 44.5576 | 1 | 19 |
| Vpr | Human immunodeficiency virus 1 | Potency | 43.9284 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 16.1870 | 2 | 2 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 3.0500 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | IC50 | 48.2500 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 5.6947 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 3.6239 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 4.6042 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 2.4117 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 4.6042 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 2.4117 | 1 | 1 |
| 5-lipoxygenase | Bos taurus (cattle) | IC50 | 3.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 153.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 3.0500 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Acetylcholinesterase | Anopheles gambiae (African malaria mosquito) | IC50 | 0.1128 | 2 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 3.1000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1.9512 | 4 | 4 |
| Acetylcholinesterase | Drosophila melanogaster (fruit fly) | IC50 | 1.8300 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 1.6138 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 0.9060 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 0.6389 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.3611 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.6389 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.3611 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.6389 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.3611 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 3.2117 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 1.2044 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 6.9754 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 1.0135 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 2.0250 | 1 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 14.2088 | 2 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 3.3169 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 0.0900 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 0.3500 | 1 | 1 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 90.0000 | 1 | 1 |
| BZLF2 | Human herpesvirus 4 type 2 (Epstein-Barr virus type 2) | IC50 | 5.9700 | 1 | 1 |
| calpain II, partial | Sus scrofa (pig) | IC50 | 3.7336 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 61.7000 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 9.5200 | 1 | 1 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 4.2300 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 4.1400 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 200.0000 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 4.6200 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 5.4800 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 5.0900 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 3.4100 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 2.2300 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 4.6800 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 6.4100 | 1 | 1 |
| Carboxylic ester hydrolase | Musca domestica (house fly) | IC50 | 9.5100 | 1 | 1 |
| Carboxylic ester hydrolase | Plutella xylostella (diamondback moth) | IC50 | 1,355.5000 | 2 | 2 |
| Chain A, ODORANT-BINDING PROTEIN | Sus scrofa (pig) | IC50 | 3.9000 | 1 | 5 |
| Chain B, Odorant-binding Protein | Sus scrofa (pig) | IC50 | 3.9000 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 250.0000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 3.8200 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 3.6600 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 1.7366 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 2.2200 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 5.6132 | 2 | 2 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Dual specificity protein phosphatase 1 | Mus musculus (house mouse) | IC50 | 9.3700 | 1 | 1 |
| Dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 6.9000 | 1 | 1 |
| Endoplasmic reticulum chaperone BiP | Homo sapiens (human) | IC50 | 9.1000 | 3 | 3 |
| envelope glycoprotein | Human immunodeficiency virus 1 | IC50 | 4.8000 | 3 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.7486 | 1 | 1 |
| Estrogen receptor 1 | Homo sapiens (human) | IC50 | 2.1616 | 1 | 1 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 0.0983 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 17.9374 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 17.9374 | 1 | 1 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| fatty acid synthase | Homo sapiens (human) | IC50 | 6.7350 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| heat shock 70kDa protein 1A | Homo sapiens (human) | IC50 | 19.3500 | 2 | 2 |
| heat shock cognate 71 kDa protein isoform 1 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| heat shock cognate 71 kDa protein isoform 2 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| Hormone-sensitive lipase | Rattus norvegicus (Norway rat) | IC50 | 1.1000 | 1 | 1 |
| kallikrein-5 preproprotein | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 34.5000 | 1 | 1 |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 57.9900 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 6.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 5.5500 | 2 | 2 |
| Malate dehydrogenase, cytoplasmic | Homo sapiens (human) | IC50 | 125.0000 | 1 | 1 |
| Mcl-1 | Homo sapiens (human) | IC50 | 7.8466 | 2 | 2 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 0.1960 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 0.0876 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 2.4844 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 4 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 0.8600 | 1 | 3 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Mus musculus (house mouse) | IC50 | 11.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 20.4630 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 11.9110 | 1 | 1 |
| Plasminogen activator inhibitor 1 | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| polyadenylate-binding protein 1 | Homo sapiens (human) | IC50 | 66.0000 | 2 | 4 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 0.6443 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 3.3188 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | Ki | 4.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 14.4100 | 3 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 17.6100 | 1 | 2 |
| small ubiquitin-related modifier 2 isoform b precursor | Homo sapiens (human) | IC50 | 12.1450 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 4.3494 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 2.3106 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 4.1392 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 1.3797 | 1 | 1 |
| SUMO-1 | Homo sapiens (human) | IC50 | 22.2500 | 2 | 2 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 51.0000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 3.0870 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 3.4780 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 2.4325 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | IC50 | 3.8000 | 1 | 1 |
| Valosin-containing protein | Homo sapiens (human) | IC50 | 27.7440 | 2 | 2 |