Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms.
| Member | Definition | Class |
|---|
| 11-ketotestosterone | A 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11. | 11-oxotestosterone |
| 2-(3,4-dimethoxyphenyl)-5-amino-2-isopropylvaleronitrile | A nitrile that is pentanenitrile substituted by a 3,4-dimethoxyphenyl group at position 2, a methylamino group at position 4 and an isopropyl group at position 2. It is a metabolite of the drug verapamil. | D617 |
| 2-aminobenzimidazole | A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. | 2-aminobenzimidazole |
| 2-aminosulfonyl-benzoic acid methyl ester | A benzoate ester that is methyl benzoate substituted by a sulfamoyl group at position 2. It is a metabolite of the herbicide metsulfuron-methyl. | 2-aminosulfonyl-benzoic acid methyl ester |
| 2-hydroxyatrazine | A monohydroxy-1,3,5-triazine that is atrazine in which the chloro group has been replaced by a hydroxy group. | 4-ethylamino-6-isopropylamino-1,3,5-triazin-2-ol |
| 2,6-dichlorobenzamide | A member of the class of benzamides that is benzamide substituted by chloro groups at positions 2 and 6. | 2,6-dichlorobenzamide |
| 3-amino-5-morpholinomethyl-2-oxazolidinone | A member of the class of oxazolidinones that is 3-amino-1,3-oxazolidin-2-one substituted by a morpholin-4-ylmethyl group at position 5. It is the metabolite of furaltadone, a broad-spectrum antibacterial drug which was widely used as an additive in livestock and aquaculture feed. | 3-amino-5-morpholinomethyl-2-oxazolidinone |
| 3-phenoxybenzoic acid | A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides. | 3-phenoxybenzoic acid |
| 3-phenoxybenzylalcohol | A member of the class of benzyl alcohols that is benzyl alcohol bearing a phenoxy substituent at C-3. It is a metbaolite of the insecticide permethrin. | (3-phenoxyphenyl)methanol |
| 3,4-dichlorophenylurea | A member of the class of ureas that is urea substituted by a 3,4-dichlorophenyl group at position 1. It is a metabolite of the herbicide diuron. | diuron-desdimethyl |
| 3,5,6-trichloro-2-pyridinol | A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos. | 3,5,6-trichloro-2-pyridinol; 3,5,6-trichloropyridine-2-one |
| 4-deethylatrazine | A chloro-1,3,5-triazine that is 6-chloro-1,3,5-triazine-2,4-diamine in which one of the hydrogens of the amino group is replaced by a propan-2-yl group. | deethylatrazine |
| 4-formylaminoantipyrine | A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a formaylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It is a metabolite of aminophenazone. | 4-formylaminoantipyrine |
| 4-trifluoromethylphenol | A member of the class of (trifluoromethyl)benzenes that is p-cresol in which the methyl group is perfluorinated. It is a metabolite of the drug fluoxetine. | 4-(trifluoromethyl)phenol |
| 5-methoxyindoleacetic acid | A member of the class of indole-3-acetic acids in which the hydrogen at position 5 of indole-3-acetic acid has been replaced by a methoxy group. | 5-methoxyindole-3-acetic acid |
| 5H-dibenzo[b,f]azepine | A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. | 5H-dibenzo[b,f]azepine |
| 6-deisopropylatrazine | A diamino-1,3,5-triazine that is N-ethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6. | deisopropylatrazine |
| ampyrone | A pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole. | 4-aminoantipyrine |
| benzoylecgonine | A benzoate ester metabolite of cocaine formed by hydrolysis of the methyl ester group, catalysed by carboxylesterases. | ecgonine benzoate |
| carbamazepine epoxide | An epoxide and metabolite of carbamazepine. | carbamazepine-10,11-epoxide |
| clofibric acid | A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate. | clofibric acid |
| clopidogrel carboxylic acid | A thienopyridine that is 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-ylacetic acid substituted by a 2-chlorophenyl group at position 2. It is a metabolite of the drug clopidogrel. | clopidogrel carboxylic acid |
| desethylterbuthylazine | A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a tert-butyl group at the amino nitrogen and a chloro group at position 6. It is metabolite of the herbicide terbutylazine. | terbutylazine-desethyl |
| desvenlafaxine | A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-hydroxyphenyl group. It is a metabolite of the drug venlafaxine. | O-desmethylvenlafaxine |
| diazoxon | An organic phosphate that is diethyl hydrogen phosphate in which the hydrogen of the hydroxy group has been replaced by a 6-methyl-2-(propan-2-yl)pyrimidin-4-yl group. It is a metabolite of the pesticide diazinon. | diazoxon |
| fenofibric acid | A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate. | fenofibric acid |
| fipronil sulfone | A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfonyl, and amino groups, respectively. It is a metabolite of the agrochemical fipronil. | fipronil-sulfone |
| g 27550 | A pyrimidone that is pyrimidin-4(1H)-one substituted by a methyl group at position 6 and an isopropyl group at position 2. It is a metabolite of diazinon. | 2-isopropyl-6-methyl-4-pyrimidinone; 2-isopropyl-6-methylpyrimidin-4-ol |
| gs 4071 | A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). An antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza. | oseltamivir acid |
| methiocarb sulfoxide | A carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfinyl)phenol with the carboxy group of methylcarbamic acid. It is a metabolite of the pesticide methiocarb. | methiocarb-sulfoxide |
| n-acetylaminoantipyrine | A member of the class of pyrazoles that is antipyrine substituted by an acetylamino group at position 4. It is a drug metabolite of metamizole. | 4-acetamidoantipyrine |
| n-desmethylvenlafaxine | A monomethoxybenzene that is the N-desmethyl derivative of venlafaxine. | N-desmethylvenlafaxine |
| N,N-dimethyl-N'-p-tolylsulfamide | A member of the class of sulfamides that is N,N-dimethylsulfuric diamide substituted by a 4-methylphenyl group at the amino nitrogen atom. It is a metabolite of the agrochemical tolylfluanid. | N,N-dimethyl-N'-p-tolylsulfamide |
| n,o-didesmethylvenlafaxine | A secondary amino compound that is N-methylethanamine substituted by a 1-hydroxycyclohexyl and a 4-hydroxyphenyl group at position 1. It is a metabolite of the drug venlafaxine. | N,O-didesmethylvenlafaxine |
| n(4)-acetylsulfadiazine | A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a pyrimidin-2-yl group at the nitrogen atom. It is a metabolite of the drug sulfadiazine. | N(4)-acetylsulfadiazine |
| n(4)-acetylsulfadimethoxine | A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 4,6-dimethoxy-pyrimidin-2-yl group at the nitrogen atom. It is a metabolite of the sulfonamide antibiotic sulfadimethoxine. | N(4)-acetylsulfadimethoxine |
| n(4)-acetylsulfamethoxazole | A sulfonamide compound having a 4-acetamidophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom. | N-acetylsulfamethoxazole |
| N(4)-acetylsulfathiazole | A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 1,3-thiazol-2-yl group at the nitrogen atom. It is a metabolite of sulfathiazole. | N(4)-acetylsulfathiazole |
| ritalinic acid | A monocarboxylic acid that is phenylacetic acid substituted by a piperidin-2-yl group at position 2. It is a metabolite of the drug methylphenidate. | ritalinic acid |
| u 40481 | A member of the class of formamidines that is N-methylimidoformamide in which the hydrogen attached to the nitrogen atom has been replaced by a 2,4-dimethylphenyl group. It is a metabolite of the insecticide amitraz. | N'-(2,4-dimethylphenyl)-N-methylformamidine |
| vitamin a2 | A retinoid derived from 3,4-desaturation of the beta-ionone ring of all-trans-retinol. | all-trans-3,4-didehydroretinol |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 28.1838 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 20.0707 | 4 | 6 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 20.8258 | 2 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 32.7586 | 8 | 15 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 44.8722 | 2 | 11 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 29.0810 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 41.4249 | 1 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 50.3155 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 56.2341 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.7113 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 19.9526 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 54.4827 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.1376 | 9 | 20 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 35.8039 | 2 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 55.4401 | 5 | 8 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 19.4938 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 17.6743 | 2 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 11.4092 | 2 | 9 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 13.2731 | 4 | 7 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 48.4096 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 22.0036 | 1 | 1 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 68.5896 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 54.6792 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 75.8901 | 1 | 2 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 15.7279 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 32.3105 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 11.0692 | 1 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 36.7868 | 3 | 6 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 47.4016 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 27.8506 | 2 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 33.7390 | 3 | 14 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 25.9805 | 2 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 20.8575 | 2 | 3 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 45.7283 | 2 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 42.4080 | 2 | 4 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 31.0725 | 2 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 33.2504 | 3 | 8 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 27.4802 | 3 | 5 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 43.9307 | 1 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 43.9307 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 1.0000 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 17.8030 | 2 | 4 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 50.1187 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 0.3981 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 40.8878 | 3 | 9 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 1.9911 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 19.9942 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 46.1020 | 1 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 27.8153 | 2 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 48.4096 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 7,8-dihydro-8-oxoguanine triphosphatase | Homo sapiens (human) | IC50 | 44.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 0.6800 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 18.1750 | 2 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 73.9000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 9.3300 | 2 | 4 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | IC50 | 53.2000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 9.3950 | 2 | 4 |
| Cationic trypsin | Bos taurus (cattle) | Ki | 155.0000 | 1 | 2 |
| Chain A, Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 520.0000 | 1 | 9 |
| Chain A, Trypsin | Bos taurus (cattle) | Ki | 155.0000 | 1 | 2 |
| Chain A, Tryptase beta-2 | Homo sapiens (human) | Ki | 155.0000 | 1 | 8 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 7.9300 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0089 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | Ki | 9.3500 | 2 | 2 |
| Fatty acid-binding protein, liver | Homo sapiens (human) | Ki | 2.1200 | 1 | 3 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 6.8388 | 3 | 5 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 1,800.0000 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.8247 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 1.7850 | 2 | 2 |
| large T antigen | Betapolyomavirus macacae | IC50 | 14.3400 | 1 | 1 |
| Membrane primary amine oxidase | Homo sapiens (human) | IC50 | 4.1000 | 1 | 1 |
| Membrane primary amine oxidase | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/budgerigar/Hokkaido/1/1977(H4N6)) | IC50 | 0.0152 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/duck/Ukraine/1/1963(H3N8)) | IC50 | 0.0089 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Memphis/1/1971(H3N2)) | IC50 | 0.0039 | 3 | 3 |
| Neuraminidase | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | IC50 | 0.0175 | 19 | 23 |
| Neuraminidase | Influenza A virus (A/swine/Hong Kong/127/1982(H3N2)) | IC50 | 0.1700 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/udorn/1972(H3N2)) | IC50 | 0.5813 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/USSR/90/1977(H1N1)) | IC50 | 0.0067 | 4 | 4 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.1851 | 4 | 4 |
| Neuraminidase | Influenza B virus (B/Lee/1940) | IC50 | 0.0085 | 10 | 14 |
| Neuraminidase | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | Ki | 0.0100 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | IC50 | 1.6300 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1)) | IC50 | 0.0007 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Turkey/651242/2006(H5N1)) | IC50 | 1.4208 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/udorn/1972(H3N2)) | IC50 | 0.0029 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 22.1275 | 50 | 50 |
| P2X purinoceptor 4 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | IC50 | 34.1250 | 8 | 8 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Ki | 35.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 141.5000 | 6 | 6 |
| Potassium voltage-gated channel subfamily D member 3 | Homo sapiens (human) | IC50 | 5,011.8700 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 10,101.8945 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 950.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 34.0000 | 2 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 42.0000 | 1 | 1 |
| Pteridine reductase, putative | Trypanosoma brucei brucei TREU927 | Ki | 288.0000 | 1 | 1 |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 14.9000 | 1 | 1 |
| Regulatory protein RhlR | Pseudomonas aeruginosa PAO1 | IC50 | 284.8000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 0.0010 | 1 | 1 |
| Sialidase A | Streptococcus pneumoniae | Ki | 1.7700 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 257.8770 | 2 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.8540 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 1.0190 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.6500 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.0350 | 2 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.0150 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.3240 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 45,100.0000 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0150 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0150 | 1 | 1 |
| Transcriptional activator protein LasR | Pseudomonas aeruginosa PAO1 | IC50 | 134.1667 | 3 | 3 |
| Tryptase beta-2 | Homo sapiens (human) | Ki | 155.0000 | 1 | 2 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |