A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
| Member | Definition | Class |
|---|
| acetyl-aspartyl-glutamyl-valyl-aspartal | A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7. | Ac-Asp-Glu-Val-Asp-H |
| amastatin | A tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequence | amastatin |
| bortezomib | L-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome. | bortezomib |
| cilastatin | The thioether resulting from the formal oxidative coupling of the thiol group of L-cysteine with the 7-position of (2Z)-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin is therefore administered (as the sodium salt) with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to inactive and potentially nephrotoxic products. Cilastatin also acts as a leukotriene D4 dipeptidase inhibitor, preventing the metabolism of leukotriene D4 to leukotriene E4. | cilastatin |
| cilastatin sodium | The monosodium salt of cilastatin. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin sodium is therefore administered with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to microbiologically inactive and potentially nephrotoxic products. | cilastatin sodium |
| e 64 | | E64 zwitterion; E64 |
| GRL-0617 | A benzamide resulting from the formal condensation of the carboxy group of 5-amino-2-methylbenzoic acid with the amino group of (1R)-1-(naphthalen-1-yl)ethan-1-amine. It is a potent noncovalent inhibitor (IC50 = 600 nM) of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). | GRL-0617 |
| KOM70144 | A benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively). | KOM70144 |
| z-val-ala-asp(ome)-fluoromethylketone | A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor. | Z-Val-Ala-Asp(OMe)-CH2F |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| AR protein | Homo sapiens (human) | Potency | 0.8203 | 7 | 12 |
| Ataxin-2 | Homo sapiens (human) | Potency | 0.0200 | 1 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.0204 | 2 | 4 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 0.2113 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 0.0067 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 0.2113 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 0.0067 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 1.5095 | 2 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 75.1930 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 3.8849 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0180 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 0.1326 | 9 | 15 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 1.5092 | 2 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0194 | 6 | 7 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 9.8972 | 4 | 7 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 6.0492 | 2 | 2 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 0.0332 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 16.7185 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 0.0127 | 2 | 4 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.0596 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 6.5131 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 0.2881 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 15.5565 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 6.5131 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 0.0498 | 2 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 0.0216 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 0.0106 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 0.1111 | 3 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 0.0472 | 3 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 0.2684 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 79.4328 | 1 | 1 |
| polyprotein | Zika virus | Potency | 0.0332 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 0.0415 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 0.0084 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 0.9439 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.0386 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 0.0094 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0668 | 2 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 6.5131 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 0.0092 | 2 | 4 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 0.7943 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 70.7946 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 0.0250 | 3 | 5 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 1.8738 | 3 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.0596 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome complex subunit SEM1 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 1 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 11 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 12 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 13 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 14 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 2 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 3 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 4 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 6 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 7 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome non-ATPase regulatory subunit 8 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 10B | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 4 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 6A | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 7 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| 26S proteasome regulatory subunit 8 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 1.1000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | Ki | 0.2000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | Ki | 0.6800 | 3 | 3 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | IC50 | 1.1000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.5800 | 1 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ATP-dependent Clp protease proteolytic subunit | Staphylococcus aureus subsp. aureus NCTC 8325 | IC50 | 5.3000 | 1 | 1 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 3 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 3 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 3 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 7.3000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Calpain-1 catalytic subunit | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Calpain-1 catalytic subunit | Sus scrofa (pig) | Ki | 3.9600 | 1 | 1 |
| Calpain-9 | Homo sapiens (human) | IC50 | 55.7900 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 1.2900 | 2 | 2 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 5.8700 | 1 | 1 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 8.4500 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 3.2800 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 2.6800 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 1.1600 | 2 | 2 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 4.5700 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 6.5100 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 6.9200 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 6.8300 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 4.3800 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 6.9400 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 3.3800 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 7.0641 | 5 | 10 |
| Caspase-1 | Homo sapiens (human) | Ki | 0.0091 | 1 | 2 |
| Caspase-2 | Homo sapiens (human) | IC50 | 0.0210 | 1 | 1 |
| Caspase-3 | Homo sapiens (human) | IC50 | 0.0340 | 17 | 22 |
| Caspase-3 | Homo sapiens (human) | Ki | 0.0091 | 1 | 2 |
| Caspase-6 | Homo sapiens (human) | IC50 | 0.0077 | 3 | 5 |
| Caspase-7 | Homo sapiens (human) | IC50 | 0.0560 | 10 | 15 |
| Caspase-8 | Homo sapiens (human) | IC50 | 0.0602 | 5 | 10 |
| Cathepsin B | Homo sapiens (human) | IC50 | 6.0141 | 5 | 5 |
| Cathepsin B | Homo sapiens (human) | Ki | 16.0000 | 1 | 1 |
| Cathepsin G | Homo sapiens (human) | IC50 | 1.8100 | 2 | 2 |
| Cathepsin G | Homo sapiens (human) | Ki | 0.6300 | 1 | 1 |
| Cathepsin S | Homo sapiens (human) | IC50 | 0.0070 | 1 | 1 |
| Chain A, caspase-3, p17 subunit | Homo sapiens (human) | Ki | 0.0013 | 1 | 3 |
| Chain B, caspase-3, p12 subunit | Homo sapiens (human) | Ki | 0.0013 | 1 | 3 |
| Chain H, Proteasome component PUP1 | Saccharomyces cerevisiae (brewer's yeast) | Ki | 0.0006 | 1 | 1 |
| Chain I, Proteasome component PUP3 | Saccharomyces cerevisiae (brewer's yeast) | Ki | 0.0006 | 1 | 1 |
| Chain K, Proteasome component PRE2 | Saccharomyces cerevisiae (brewer's yeast) | Ki | 0.0006 | 1 | 2 |
| Chain L, Proteasome component C5 | Saccharomyces cerevisiae (brewer's yeast) | Ki | 0.0006 | 1 | 2 |
| Chymase | Homo sapiens (human) | IC50 | 1.1900 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | Ki | 2.4000 | 1 | 1 |
| Chymotrypsinogen B | Homo sapiens (human) | Ki | 0.3200 | 1 | 1 |
| Cruzipain | Trypanosoma cruzi | IC50 | 0.2100 | 2 | 2 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 0.0031 | 1 | 1 |
| Cysteine protease | Trypanosoma brucei rhodesiense | Ki | 0.0350 | 1 | 1 |
| Cysteine protease falcipain-3 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.1972 | 3 | 3 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0828 | 6 | 6 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 13.6267 | 3 | 3 |
| Cytosol aminopeptidase | Homo sapiens (human) | Ki | 5.1125 | 4 | 4 |
| Dipeptidase 1 | Sus scrofa (pig) | Ki | 0.1700 | 1 | 3 |
| Dipeptidyl peptidase 1 | Homo sapiens (human) | IC50 | 0.7700 | 1 | 1 |
| Fatty acid synthase | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| Glutamyl aminopeptidase | Homo sapiens (human) | Ki | 8.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 0.6200 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 1.1800 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 69.4400 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 0.0720 | 1 | 1 |
| Leucyl-cystinyl aminopeptidase | Rattus norvegicus (Norway rat) | Ki | 0.1200 | 2 | 2 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Ki | 0.0300 | 1 | 2 |
| Liver carboxylesterase | Sus scrofa (pig) | IC50 | 300.0000 | 1 | 1 |
| Lon protease homolog, mitochondrial | Homo sapiens (human) | IC50 | 0.1830 | 1 | 1 |
| Lysosomal protective protein | Homo sapiens (human) | IC50 | 154.6000 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 0.0407 | 1 | 1 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Neutrophil elastase | Homo sapiens (human) | Ki | 2.3000 | 1 | 1 |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | IC50 | 0.0850 | 1 | 1 |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | IC50 | 0.0850 | 1 | 1 |
| Papain | Carica papaya (papaya) | IC50 | 0.0187 | 3 | 3 |
| Papain | Carica papaya (papaya) | Ki | 5.0800 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 0.0300 | 1 | 1 |
| Pro-cathepsin H | Homo sapiens (human) | IC50 | 0.1900 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.1856 | 6 | 7 |
| Procathepsin L | Homo sapiens (human) | Ki | 0.0300 | 1 | 1 |
| Proteasomal ubiquitin receptor ADRM1 | Homo sapiens (human) | IC50 | 0.5335 | 4 | 4 |
| Proteasome subunit alpha type-1 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-2 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-3 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-4 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-5 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-6 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha type-7 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit alpha-type 8 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit beta type-1 | Homo sapiens (human) | IC50 | 0.2149 | 18 | 18 |
| Proteasome subunit beta type-10 | Homo sapiens (human) | IC50 | 0.5359 | 10 | 10 |
| Proteasome subunit beta type-11 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit beta type-2 | Homo sapiens (human) | IC50 | 2.9860 | 19 | 19 |
| Proteasome subunit beta type-3 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit beta type-4 | Homo sapiens (human) | IC50 | 0.3213 | 7 | 7 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 15,084.2836 | 32 | 34 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | Ki | 0.0067 | 3 | 3 |
| Proteasome subunit beta type-6 | Homo sapiens (human) | IC50 | 0.2842 | 8 | 8 |
| Proteasome subunit beta type-7 | Homo sapiens (human) | IC50 | 1.8772 | 8 | 8 |
| Proteasome subunit beta type-8 | Homo sapiens (human) | IC50 | 0.1681 | 14 | 14 |
| Proteasome subunit beta type-8 | Mus musculus (house mouse) | IC50 | 0.0168 | 1 | 1 |
| Proteasome subunit beta type-9 | Homo sapiens (human) | IC50 | 0.2059 | 11 | 11 |
| Prothrombin | Homo sapiens (human) | Ki | 13.0000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.5800 | 1 | 2 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 0.5800 | 1 | 2 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 0.5800 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 2.7993 | 12 | 15 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.9180 | 3 | 5 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 2,550.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | IC50 | 2,387.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 1,470.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | IC50 | 249.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | IC50 | 742.0000 | 1 | 1 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 231.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.5800 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.5800 | 1 | 2 |
| Transcription factor p65 | Homo sapiens (human) | IC50 | 0.0850 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.5800 | 1 | 2 |