A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays.
| Member | Definition | Class |
|---|
| amidotrizoic acid dihydrate | The dihydrate form of amidotrizoic acid. Both the dihydrate and the anhydrous form are used as X-ray contrast media. | amidotrizoic acid dihydrate |
| barium sulfate | A metal sulfate with formula BaO4S. Virtually insoluble in water at room temperature, it is mostly used as a component in oil well drilling fluid it occurs naturally as the mineral barite. | barium sulfate |
| diatrizoate meglumine | The N-methylglucamine salt of amidotrizoic acid. Both the sodium and the meglumine salts of amidotrizoic acid have been widely used as water-soluble radioopaque media in diagnostic radiography. The use of a mixture of the two salts is often preferred, as adverse effects can be reduced. | meglumine amidotrizoate |
| diatrizoic acid | A member of the class of benzoic acids that is benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, mainly as its N-methylglucamine and sodium salts, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography. | amidotrizoic acid |
| fluorescein | A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy. | fluorescein (lactone form) |
| fluorescite | A xanthene dye that is highly fluorescent and commonly used as a fluorescent tracer. | fluorescein (acid form) |
| iobitridol | A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a 3-hydroxy-2-(hydroxymethyl)propanimido at position 5. | iobitridol |
| iodamide | A benzoic acid compound having iodo substituents at the 2-, 4- and 6-positions, an acetamido substituent at the 3-position and an acetamidomethyl substituent at the 5-position. | iodamide |
| iodipamide | An organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography. | adipiodone |
| iodixanol | A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography. | iodixanol |
| iohexol | A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position. | iohexol |
| iomeprol | A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position. | iomeprol |
| iopamidol | A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. | iopamidol |
| iopromide | A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration. | iopromide |
| ioxaglate | A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position. | ioxaglic acid |
| ioxitalamic acid | An organoiodine compound that is 2,4,6-triiodobenzoic acid substituted by an acetylamino group at position 3 and a (2-hydroxyethyl)carbamoyl group at position 5. It is used as a contrast medium. | iooxitalamic acid |
| meglumine iodipamide | An organoammonium salt obtained by reaction of adipiodone with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. It is a contrast agent used in diagnostic imaging. | iodipamide dimeglumine |
| metrizoate | | metrizoic acid |
| perflexane | A fluoroalkane that is hexane in which all of the hydrogens have been replaced by fluorines. | perfluorohexane |
| perflubron | A haloalkane that is perfluorooctane in which a fluorine attached to one of the terminal carbons has been replaced by a bromine. | perflubron |
| perfluoropentane | A fluorocarbon that is pentane in which all of the hydrogens have been replaced by fluorines. | perfluoropentane |
| perfluorophenanthrene | | perfluorophenanthrene |
| sodium diatrizoate | The sodium salt of a benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, often as a mixture with the meglumine salt, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography. | sodium amidotrizoate |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 0.5638 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 41.2434 | 2 | 2 |
| AR protein | Homo sapiens (human) | Potency | 18.8893 | 7 | 12 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 21.6899 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 29.8304 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 30.4254 | 2 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 54.5326 | 3 | 5 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 20.2208 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 11.2202 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 35.4813 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 19.9504 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 0.0116 | 1 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 43.6486 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 19.3471 | 1 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 7.1669 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 29.4124 | 1 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 24.1903 | 6 | 15 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 54.4827 | 2 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 16.3103 | 6 | 9 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 16.6789 | 1 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 19.3776 | 3 | 4 |
| geminin | Homo sapiens (human) | Potency | 10.3885 | 2 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 22.3040 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 19.0740 | 3 | 11 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 29.9758 | 2 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 28.1838 | 1 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 30.4765 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 24.6554 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 0.0316 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 43.6465 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 9.2000 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.5391 | 1 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 0.4929 | 1 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 25.5572 | 2 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 48.9722 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 7.4334 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 8.8444 | 2 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 25.9850 | 3 | 5 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 19.8120 | 3 | 4 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.5596 | 2 | 4 |
| progesterone receptor | Homo sapiens (human) | Potency | 54.4827 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 9.2832 | 2 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 76.9588 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 28.2145 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 35.5964 | 3 | 3 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 35.5964 | 3 | 3 |
| snurportin-1 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 30.7369 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 56.2341 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 51.0530 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 0.3455 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 178.0194 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 34.0954 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 19.9306 | 3 | 4 |