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Egyptian Ophthalmia

A chronic infection of the CONJUNCTIVA and CORNEA caused by CHLAMYDIA TRACHOMATIS.

Synonyms(2)

Synonym
Egyptian Ophthalmia
Trachoma

Research Excerpts

Overview

ExcerptReference
"trachomatis serotypes in 32 inclusion positive school children suffering from trachoma."( Kumar, VN; Satpathy, G; Sujata, M, 1991)
"PCR-EIA detected C trachomatis in 24%, 54%, and 95% of subjects, respectively, compared with elementary body (EB) detection by DFA of 1%, 28%, and 60%, respectively."( Bobo, L; Mkocha, H; Munoz, B; Quinn, T; Viscidi, R; West, S, 1991)
"trachomatis (TW-5), had a reduction in the percentage of inclusion-containing cells by over 80% in a dose-dependent manner."( Byrne, GI; Carlin, JP; Miller, SL; Padilla, ML; Rapoza, PA; Tahija, SG, 1991)
"Trachoma is the leading infectious cause of blindness worldwide, and epidemiologic studies of factors that may increase the transmission of ocular Chlamydia trachomatis are needed."( Congdon, N; Katala, S; Mele, L; West, SK, 1991)
"trachomatis serovars B, C, and E."( Taylor, HR, 1990)
"trachomatis serovar L1 was used as a probe to locate the 60 kDa CrP gene of a recent serovar B trachoma isolate (Jali 20/OT)."( Clarke, IN; Lambden, PR; Ward, ME; Watson, MW, 1989)
"trachomatis in the conjunctival epithelium of patients with trachoma."( Booth-Mason, S; Mabey, DC, 1986)
"Active trachoma is characterized by chronic inflammation of the conjunctiva, and repeated episodes of reinfection are thought to be necessary to sustain this inflammation."( Caldwell, HD; Johnson, SL; Prendergast, RA; Schachter, J; Taylor, HR, 1987)
"The prevalence of trachoma is lower in pastoralists who herd mainly camels than in pastoralists who herd mainly cattle."( De Sole, G, 1987)
"In addition, trachoma is aggravated if there are associated bacterial infections and these lead to more frequent corneal complications."( Kupka, K; Maxwell-Lyons, F; Nizetic, B; Reinhards, J; Weber, A, 1968)
"In areas where trachoma is common special clinics should be established for the treatment and follow-up of patients and contacts."( Howells, CH; Johnson, L; Soni, KG; Woodhouse, DF, 1969)
"C."( Ripa, KT, 1982)
"C."( Smith, TF; Weed, LA, 1983)
"trachomatis correlates well with in vitro activity if sufficient antimicrobial is given for a long enough duration."( Bowie, WR, 1982)
"trachomatis (serovar C) elementary bodies."( Campos, M; O'Brien, TP; Pal, S; Prendergast, RA; Taylor, HR; Whittum-Hudson, JA, 1995)
"trachomatis inclusion-formation."( Babikir, HE; Elhassan, AE; Fröman, G; Mahmoud, EA; Mårdh, PA, 1994)
"Blindness due to trachoma is a serious public health issue world wide."( Arullendran, P; Bailey, RL; Mabey, DC; Whittle, HC, 1993)
"trachomatis infection."( Arullendran, P; Bailey, RL; Mabey, DC; Whittle, HC, 1993)
"In conclusion, C."( Bobo, L; Mkocha, H; Novak, N; Quinn, TC; Vitale, S; West, S, 1996)
"Chlamydia trachomatis is the leading cause worldwide of preventable infectious blindness (trachoma) and sexually transmitted disease, including nongonoccocal urethritis and pelvic inflammatory disease."( An, LL; MacDonald, AB; Prendergast, RA; Saltzman, WM; Whittum-Hudson, JA, 1996)
"Chlamydia trachomatis consists of two biovars, lymphogranuloma venereum (LGV) and trachoma, that differ in their infectivity in vivo and in vitro."( Chen, JC; Stephens, RS, 1997)
"trachomatis 5."( Imrie, M; McKenzie, H; Norman, J; Penney, GC; Smith, R; Thomson, M; Vale, L, 1998)
"Trachoma is the leading cause of preventable blindness."( Bailey, R; Bobo, L; Dawson, CR; Faal, H; Mabey, D; Mkocha, H; Quinn, TC; Sallam, S; Schachter, J; Sheta, A; Vitale, S; West, SK, 1999)
"trachomatis infection and clinical trachoma in endemic areas and may be an important approach to control of trachoma."( Bailey, R; Bobo, L; Dawson, CR; Faal, H; Mabey, D; Mkocha, H; Quinn, TC; Sallam, S; Schachter, J; Sheta, A; Vitale, S; West, SK, 1999)
"Trachoma is a leading cause of preventable blindness worldwide."( Tabbara, KF, 2001)
"Chlamydia trachomatis was suspected in 2."( Alió, JL; Ferrer, C; Javaloy, J; Vidal, MT, 2003)
"Cicatricial trachoma is more frequent."( Alió, JL; Ferrer, C; Javaloy, J; Vidal, MT, 2003)
"Clinically active trachoma is not always a reliable marker of infection, particularly in teenagers and after treatment."( Bassem, A; Bird, M; Dawson, CR; Lietman, TM; Miao, Y; Osman, A; Schachter, JS; Shama, A, 2003)
"Trachoma is an ocular disease caused by repeated infection with Chlamydia trachomatis."( Buchan, J; Foster, A; Kuper, H; Mabey, D; Solomon, AW; Zondervan, M, 2003)
"Trachoma is the world's leading cause of preventable blindness."( Kumaresan, JA; Mecaskey, JW, 2003)
"trachomatis before and 2, 6, 12, 18, and 24 months after mass treatment with azithromycin in a Tanzanian community in which trachoma was endemic."( Aguirre, A; Alexander, ND; Bailey, RL; Courtright, P; Foster, A; Holland, MJ; Mabey, DC; Massae, PA; Molina, S; Natividad-Sancho, A; Peeling, RW; Safari, S; Shao, JF; Solomon, AW; West, SK, 2004)
"trachomatis infection in the community was 13."( Aguirre, A; Alexander, ND; Bailey, RL; Courtright, P; Foster, A; Holland, MJ; Mabey, DC; Massae, PA; Molina, S; Natividad-Sancho, A; Peeling, RW; Safari, S; Shao, JF; Solomon, AW; West, SK, 2004)
"trachomatis infection."( Aguirre, A; Alexander, ND; Bailey, RL; Courtright, P; Foster, A; Holland, MJ; Mabey, DC; Massae, PA; Molina, S; Natividad-Sancho, A; Peeling, RW; Safari, S; Shao, JF; Solomon, AW; West, SK, 2004)
"Trachoma is the most important infectious cause of blindness worldwide."( Cumberland, P; Hailu, G; Todd, J, 2005)
"trachomatis load (COCTL) which is similar to the community microfilarial load (CMFL) of onchocerciasis."( Alexander, ND; Bailey, RL; Foster, A; Holland, MJ; Mabey, DC; Shao, JF; Solomon, AW; West, SK, 2005)
"Trachoma is a chronic granular conjunctivitis due to Chlamydia trachomatis serotypes A to C."( Labetoulle, M; Raymond, J, 2005)
"Trachoma is the leading infectious cause of blindness worldwide."( Alemayehu, W; Imeru, A; Melese, M; Munoz, B; West, ES; West, SK, 2005)
"Trachoma is a major cause of blindness."( Buchan, JC; Foster, A; Kuper, H; Mabey, D; Solomon, AW; Zondervan, M, 2005)
"Chlamydia trachomatis ocular and urogenital infections represent major public health problems, whereas Chlamydophila pneumoniae is a common aetiological agent of community-acquired pneumonia."( Greub, G; Hammerschlag, MR; Senn, L, 2005)
"Trachoma is one of the leading preventable causes of blindness worldwide."( Cumberland, P; Edwards, T; Hailu, G; Todd, J, 2006)
"Infection with C trachomatis did not differ between groups at 6 months post-treatment (9%vs 7%, p=0."( Bailey, R; Emerson, PM; Mabey, D; McHiwa, W; Mkocha, H; Munoz, B; West, SK, 2006)
"Trachoma is a neglected disease and also the world's leading infectious cause of blindness."( Bailey, R; Burton, M; Emerson, PM; Mabey, D; Solomon, AW, 2006)
"Trachoma is the leading infectious cause of blindness."( Aguirre, A; Bailey, R; Burton, MJ; Gower, EW; Holland, M; Mabey, DC; Makalo, P; Massae, P; Mkocha, H; Muñoz, B; Solomon, AW; West, SK, 2006)
"trachomatis infection are discussed."( Behrens-Baumann, W, 2007)
"trachomatis were determined in a community 3."( Gaydos, C; Mkocha, H; Munoz, B; Quinn, T; West, SK, 2007)
"trachomatis infection were not eliminated in this trachoma hyperendemic village 3."( Gaydos, C; Mkocha, H; Munoz, B; Quinn, T; West, SK, 2007)
"In conclusion, trachoma is a common disease of public-health importance only in the low- and mid-altitude villages in the Gurage zone, where there are large numbers of eye-seeking flies, and not in the villages that lie >3000 m above sea level, where there is a dearth of such flies."( Alemayehu, W; Asfaw, T; Geyid, A; Mekonnen, Y; Melese, M; Taye, A; Tilahun, D, 2007)
"trachomatis transmission were assessed."( Courtenay, O; Favacho, J; Garcez, LM; Reilly, LA, 2007)
"trachomatis by polymerase chain reaction."( Andreason, A; Cumberland, P; Edwards, T; Hailu, G; Harding-Esch, EM; Mabey, DC; Todd, J, 2008)
"Odds of C."( Andreason, A; Cumberland, P; Edwards, T; Hailu, G; Harding-Esch, EM; Mabey, DC; Todd, J, 2008)
"trachomatis and active trachoma were identified."( Andreason, A; Cumberland, P; Edwards, T; Hailu, G; Harding-Esch, EM; Mabey, DC; Todd, J, 2008)
"trachomatis DNA."( Andreasen, A; Cumberland, P; Edwards, T; Hailu, G; Harding-Esch, E; Mabey, D; Todd, J, 2008)
"trachomatis infection was only 0."( Aryee, EA; Bailey, RL; Edwards, T; Harding-Esch, EM; Holland, MJ; Mabey, DC; Sarr-Sissoho, I; Sillah, A; Snell, P, 2008)
"trachomatis in children in a hyperendemic village in Tanzania."( Mkocha, H; Muñoz, BE; West, SK; Wolle, MA, 2009)
"The prevalence of trachoma is high."( Goyol, M; Mpyet, C; Ogoshi, C, 2010)
"Trachoma is the leading infectious cause of blindness."( Alemayehu, W; Gaynor, BD; Halfpenny, C; Hong, KC; House, J; Keenan, JD; Lakew, T; Lietman, TM; Porco, TC; Shah, NA; Whitcher, JP, 2010)
"Trachoma is the commonest infectious cause of blindness."( Bailey, RL; Burton, MJ; Harding-Esch, EM; Hu, VH; Kadimpeul, J; Mabey, DC, 2010)
"Infection with C."( Abdou, A; Baarè, I; Kadri, B; Moussa, F; Munoz, BE; Nassirou, B; Opong, E; Riverson, J; West, SK, 2010)
"trachomatis infection in endemic communities in Niger."( Abdou, A; Baarè, I; Kadri, B; Moussa, F; Munoz, BE; Nassirou, B; Opong, E; Riverson, J; West, SK, 2010)
"Trachoma is the leading infectious cause of blindness."( Bailey, RL; Burton, MJ; Holland, MJ; Mabey, DC; Makalo, P; Rajak, SN; Sillah, A, 2010)
"trachomatis were collected at baseline, 6 months, and 1 year."( Bailey, RL; Burton, MJ; Holland, MJ; Mabey, DC; Makalo, P; Rajak, SN; Sillah, A, 2010)
"Trachoma is a major cause of blindness in the developing world and 63 million people are currently infected."( Basáñez, MG; Blake, IM; Gambhir, M; Grassly, NC, 2010)
"trachomatis infection in randomly selected children aged 0-5 years from 48 Gambian and 36 Tanzanian communities."( Bailey, RL; Burr, SE; Edwards, T; Gaydos, CA; Harding-Esch, EM; Holland, MJ; Mabey, DC; Mkocha, H; Munoz, B; Sillah, A; Stare, D; West, SK, 2010)
"trachomatis infection in this setting."( Bailey, RL; Burr, SE; Edwards, T; Gaydos, CA; Harding-Esch, EM; Holland, MJ; Mabey, DC; Mkocha, H; Munoz, B; Sillah, A; Stare, D; West, SK, 2010)
"Trachoma is the principal cause of infectious blindness."( Bailey, R; Gaydos, C; Harding-Esch, E; Holland, M; Mabey, D; Munoz, B; Stare, D; West, S, 2011)
"Trachoma is the world's leading infectious cause of blindness."( Evans, JR; Solomon, AW, 2011)
"Trachoma is the leading infectious cause of blindness in the world, and for endemic communities, mass treatment with azithromycin reduces the pool of infection."( Cajas-Monson, LC; Gaydos, CA; Mkocha, H; Muñoz, B; Quinn, TC; West, SK, 2011)
"trachomatis infection."( Gaydos, CA; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2011)
"trachomatis infection were related to the extent of the previous year's azithromycin coverage."( Gaydos, CA; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2011)
"trachomatis at baseline, and 6 months after mass drug administration."( Gaydos, C; Mkocha, H; Munoz, B; Quinn, TC; Stare, D; West, SK, 2011)
"trachomatis by Amplicor Polymerase Chain Reaction."( Andreasen, AA; Bailey, RL; Edwards, T; Harding, EF; Harding-Esch, EM; Holland, MJ; Mabey, DC; Molina, S; Roberts, Ch; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2011)
"trachomatis as its specificity decreases in hot and dry conditions: the environment in which trachoma is predominantly found."( Andreasen, AA; Bailey, RL; Edwards, T; Harding, EF; Harding-Esch, EM; Holland, MJ; Mabey, DC; Molina, S; Roberts, Ch; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2011)
"Surgery for trachoma is more cost effective than extra-capsular cataract surgery and can reverse trichiasis (in-growing eyelashes), but needs to be repeated every few years."( Baneke, A, 2012)
"Anti-Chlamydial trachomatis (anti-CT) responses, particularly anti-heat shock 60 (Hsp60), antibodies confer a higher risk of ectopic pregnancy."( Daponte, A; Deligeoroglou, E; Messinis, IE; Pournaras, S; Skentou, H, 2012)
"Trachoma is the leading cause of preventable blindness worldwide."( Ketema, K; Muluye, D; Tiruneh, M; Woldeyohannes, D, 2012)
"Active trachoma is a major public problem among 1-9 years children and significantly associated with a number of risky factors."( Ketema, K; Muluye, D; Tiruneh, M; Woldeyohannes, D, 2012)
"Chlamydia trachomatis is a gram-negative bacterium that infects the columnar epithelium of the cervix, urethra, and rectum, as well as nongenital sites such as the lungs and eyes."( McClaskey, EL; Mishori, R; WinklerPrins, VJ, 2012)
"The prevalence of C trachomatis at 18 months."( Bailey, R; Gaydos, CA; Lietman, TA; Mkocha, H; Munoz, B; Quinn, T; West, SK; Yohannan, J, 2013)
"Infection with C trachomatis in communities with average trachoma rates at 12% to 13% cannot be eliminated before 3 rounds of MDA with azithromycin."( Bailey, R; Gaydos, CA; Lietman, TA; Mkocha, H; Munoz, B; Quinn, T; West, SK; Yohannan, J, 2013)
"Trachoma is a public health problem in Ethiopia accounting for 35-50% of cases of blindness."( Jemaneh, AA; Mekonnen, MG; Yalew, KN, 2012)
"trachomatis infection."( Bailey, RL; Basáñez, MG; Blake, IM; Burton, MJ; Donnelly, CA; Gambhir, M; Grassly, NC; Koukounari, A; Mabey, DC; Moustaki, I; Solomon, AW, 2013)
"Trachoma is the leading cause of infectious blindness worldwide."( Ejigu, M; Gelaw, Y; Ilako, DR; Kariuki, MM, 2013)
"Trachoma is endemic in Kersa District with active trachoma being a public health problem in the studied sub-districts."( Ejigu, M; Gelaw, Y; Ilako, DR; Kariuki, MM, 2013)
"Trachoma is the leading cause of infectious blindness worldwide."( Palmer, SL; Stauber, C; Strasser, S; Travers, A, 2013)
"trachomatis infection was less than 5%."( Bailey, R; Edwards, T; Gaydos, C; Lietman, T; Mabey, D; Mkocha, H; Munoz, B; Porco, T; Quinn, TC; West, SK, 2013)
"Chlamydia trachomatis isolates were obtained before and after MDA in 15 paired samples and were tested for antimicrobial susceptibility."( Gaydos, CA; Hardick, J; Mkocha, H; Moncada, J; Munoz, B; Quinn, TC; Schachter, J; Storey, P; West, SK, 2014)
"Trachoma is the world's leading cause of infectious blindness."( Addiss, DG; Freeman, MC; Haddad, D; McGuire, C; Ogden, S; Stocks, ME, 2014)
"trachomatis infection (OR 0."( Addiss, DG; Freeman, MC; Haddad, D; McGuire, C; Ogden, S; Stocks, ME, 2014)
"trachomatis infection and TF were assessed in 3,200 randomly sampled children aged five years and younger, who were examined prior to each MDA."( Gaydos, CA; Lee, JS; Mkocha, H; Muñoz, BE; Quinn, TC; West, SK, 2014)
"trachomatis infection and TF weakened in children with each MDA, as both infection and clinical disease prevalence declined."( Gaydos, CA; Lee, JS; Mkocha, H; Muñoz, BE; Quinn, TC; West, SK, 2014)
"trachomatis DNA and antibody responses for IgA and total IgG were measured in dried bloods spots."( Dize, L; Gaydos, C; Goodhew, EB; Lammie, PJ; Martin, DL; Mkocha, H; Morgan, SM; Munoz, B; Switzer, AJ; West, SK; Wiegand, RE, 2014)
"trachomatis infection in the differential diagnosis of acute or chronic follicular conjunctivitis among sexually active young individuals."( Carvalho, AC; Franzoni, A; Gargiulo, F; Matteelli, A; Sulis, G; Urbinati, L, 2014)
"Chlamydia trachomatis is an obligate intracellular epitheliotropic bacterial pathogen of humans."( Caldwell, HD; Carlson, JH; Kanakabandi, K; Porcella, SF; Song, L; Sturdevant, DE; Sturdevant, GL; Virtaneva, K; Whitmire, WM; Wilder, H, 2015)
"Blinding trachoma is targeted for elimination by 2020 using the SAFE strategy (Surgery, Antibiotics, Facial cleanliness, and Environmental improvements)."( Emerson, PM; Gelderblom, HC; Haddad, D; Jimenez, V; Mann Flueckiger, R, 2015)
"Trachoma is the leading infectious cause of blindness worldwide."( Berhe, R; Gedefaw, M; Nigusie, A, 2015)
"Trachoma is targeted for elimination by 2020."( Black, CM; Dize, L; Gambhir, M; Gaydos, CA; Goodhew, B; Kasubi, M; Lammie, P; Martin, DL; Mkocha, H; West, S; Wiegand, R, 2015)
"Trachoma is a blinding disease caused by conjunctival infection with Chlamydia trachomatis (Ct)."( Bailey, RL; Cassama, E; Derrick, T; Holland, MJ; Last, AR; Markham-David, R; Marks, M; Nabicassa, M, 2016)
"Active trachoma is caused by chronic infection of the conjunctiva by Chlamydia trachomatis, and is the world's leading infectious cause of blindness."( Lansingh, VC, 2016)
"Chlamydia trachomatis is the most common bacterial sexually transmitted infection and is frequently asymptomatic; ocular C."( Bottomley, C; Butcher, R; Kako, H; Mabey, DC; Marks, M; Pitakaka, R; Sokana, O; Solomon, AW; Tome, H, 2016)
"trachomatis and Neisseria gonorrhoeae using the BD Probetec strand displacement assay."( Bottomley, C; Butcher, R; Kako, H; Mabey, DC; Marks, M; Pitakaka, R; Sokana, O; Solomon, AW; Tome, H, 2016)
"C."( Bottomley, C; Butcher, R; Kako, H; Mabey, DC; Marks, M; Pitakaka, R; Sokana, O; Solomon, AW; Tome, H, 2016)
"trachomatis infection following azithromycin MDA for trachoma elimination."( Bottomley, C; Butcher, R; Kako, H; Mabey, DC; Marks, M; Pitakaka, R; Sokana, O; Solomon, AW; Tome, H, 2016)
"Trachoma is the leading infectious cause of blindness and is caused by ocular infection with the bacterium Chlamydia trachomatis (Ct)."( Alexander, N; Butcher, R; Cikamatana, L; Kama, M; Mabey, DC; Macleod, CK; Mudaliar, U; Natutusau, K; Pavluck, AL; Rafai, E; Roberts, CH; Solomon, AW; Willis, R, 2016)
"Both yaws and trachoma are endemic in the Pacific."( Bottomley, C; Kilua, G; Mabey, DC; Marks, M; Nachamkin, E; Pillay, A; Puiahi, E; Sokana, O; Solomon, AW, 2016)
"Trachoma is a serious public health problem in rural Ethiopia."( Bekele, Z; Muluneh, EK; Zewotir, T, 2016)
"trachomatis infection."( Dize, L; Dreger, K; Ervin, AM; Gaydos, C; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2016)
"trachomatis were equivalent between the two arms (5."( Dize, L; Dreger, K; Ervin, AM; Gaydos, C; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2016)
"trachomatis B to infect human conjunctival epithelial cells (HCjE) and studied the effects of wIRA on non-infected ocular structures with two ex vivo eye models."( Barisani-Asenbauer, T; Blenn, C; Borel, N; Frohns, A; Frohns, F; Leonard, CA; Marti, H; Rahn, C; Stein, E, 2016)
"Trachoma is a public health issue in PNG."( Burnett, A; Garap, J; Keys, D; Ko, R; Macleod, C; Pahau, D; Sokana, O; Solomon, AW; Wabulembo, G; Willis, R, 2016)
"The prevalence of trachoma is relatively low in most of Niger State."( Adamu, MD; Bosso, UA; Chu, BK; Flueckiger, RM; Isiyaku, S; Mpyet, C; Muazu, H; Muhammad, N; Nwobi, BC; Olamiju, F; Olobio, N; Onyebuchi, U; Pavluck, A; Solomon, AW; Umar, MM; William, A; Willis, R, 2016)
"Trachoma is a major cause of blindness in Ethiopia, and targeted for elimination as a public health problem by the year 2020."( Abashawl, A; Adamu, L; Adamu, Y; Chu, BK; Dejene, M; Fikru, W; Flueckiger, RM; Kidu, B; Macleod, C; Pavluck, AL; Solomon, AW; Willis, R, 2016)
"Active trachoma is prevalent in the Solomon Islands."( Butcher, R; Chu, BK; Jack, K; Macleod, C; Marks, M; Posala, C; Sokana, O; Solomon, AW; Willis, R, 2016)
"trachomatis urogenital serotypes (D-K) has led to concurrent increase in C."( Ahmed, NH; Behera, HS; Satpathy, G, 2017)
"trachomatis Plus RG PCR, Qiagen) using molecular diagnostics quality control standards and clinical samples."( Burton, MJ; Butcher, R; Derrick, T; Herrera, B; Holland, MJ; Houghton, J; Last, AR; Massae, PA; Ramadhani, A; Roberts, CH, 2017)
"Trachoma is targeted for global elimination."( Dize, L; Ervin, AM; Gaydos, CA; Mkocha, H; Munoz, B; Quinn, TC; Swenor, B; West, SK, 2017)
"Trachoma is chronic kerato conjunctivitis, which is caused by repeated infection with Chlamydia trachomatis bacterium."( Kumie, A; Tadesse, B; Worku, A; Yimer, SA, 2017)
"Trachoma is the leading infectious cause of blindness in the world and is associated with precarious living conditions in developing countries."( Alves da Cunha, AJL; Favacho, J; Freitas, FB; Gomes, STM; Ishak, MOG; Ishak, R; Queiroz, MAF; Vallinoto, ACR, 2018)
"Trachoma is the leading infectious cause of blindness worldwide."( Astale, T; Ayenew, G; Callahan, EK; Chanyalew, M; Gessese, D; Melak, B; Nash, SD; Nute, AW; Sata, E; Stewart, AEP; Tadesse, Z; Zerihun, M, 2018)
"trachomatis DNA."( Bayissasse, B; Callahan, EK; Chanyalew, M; Chernet, A; Emerson, PM; Endeshaw, T; Gessese, D; King, JD; Lietman, TM; Melak, B; Moncada, J; Nash, SD; Sata, E; Stewart, AEP; Tadesse, Z; Zerihun, M, 2018)
"Trachoma is a public health problem in Guinea."( Amon, JJ; Badila, CF; Baldé, MS; Bamba, IF; Géopogui, A; Lamah, L; Ngondi, J; Nieba, C; Reid, SD; Solomon, AW; Tougoue, JJ; Yattara, ML; Zhang, Y, 2018)
"Ocular Chlamydia trachomatis infection, the causative agent for trachoma, is responsible for 1."( West, SK; Wolle, MA, 2019)
"Globally, trachoma is the leading cause of blindness and is responsible for about 1."( Fernandez, R; Lapkin, S; Matchawe, C; Tanywe, AC, 2019)
"trachomatis infection and clinical signs three- and six- months post treatment relative to three pre-treatment time-points."( Bailey, RL; Burton, MJ; Derrick, T; Holland, MJ; Mabey, DCW; Macleod, D; Makupa, W; Malisa, A; Massae, P; Mbuya, K; Mtuy, T; Ramadhani, AM; Roberts, CH, 2019)
"C."( Bailey, RL; Burton, MJ; Derrick, T; Holland, MJ; Mabey, DCW; Macleod, D; Makupa, W; Malisa, A; Massae, P; Mbuya, K; Mtuy, T; Ramadhani, AM; Roberts, CH, 2019)
"trachomatis infection and inflammatory disease signs were significantly reduced three- and six- months post-mass drug administration (MDA)."( Bailey, RL; Burton, MJ; Derrick, T; Holland, MJ; Mabey, DCW; Macleod, D; Makupa, W; Malisa, A; Massae, P; Mbuya, K; Mtuy, T; Ramadhani, AM; Roberts, CH, 2019)
"Trachoma is the leading infectious cause of blindness."( Alemayehu, W; Biran, A; Burton, MJ; Greenland, K; Sarah, V; Sommers, K; White, S, 2019)
"trachomatis prevalence, organism load, and circulating strains at baseline and one-year post-MDA in The Gambia and Senegal."( Andreasen, AA; Bailey, RL; Christerson, L; Grundy, C; Harding-Esch, EM; Herrmann, B; Holland, MJ; Jeffries, D; Mabey, DCW; Molina-Gonzalez, S; Pickering, H; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2019)
"trachomatis infection and organism load (ompA copy number), and ompA and multi-locus sequence typing (MLST) was performed."( Andreasen, AA; Bailey, RL; Christerson, L; Grundy, C; Harding-Esch, EM; Herrmann, B; Holland, MJ; Jeffries, D; Mabey, DCW; Molina-Gonzalez, S; Pickering, H; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2019)
"trachomatis prevalence increased from 3."( Andreasen, AA; Bailey, RL; Christerson, L; Grundy, C; Harding-Esch, EM; Herrmann, B; Holland, MJ; Jeffries, D; Mabey, DCW; Molina-Gonzalez, S; Pickering, H; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2019)
"trachomatis infection, with heterogeneity observed between villages studied."( Andreasen, AA; Bailey, RL; Christerson, L; Grundy, C; Harding-Esch, EM; Herrmann, B; Holland, MJ; Jeffries, D; Mabey, DCW; Molina-Gonzalez, S; Pickering, H; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2019)
"Ocular C."( Alkhidir, AAI; Breuer, J; El Hussain, KMK; Elemam, AE; Elhag, WI; Holland, MJ; Ournasseir, MEH; Pickering, H; Williams, CA, 2019)
"trachomatis isolates to improve understanding of pathogen diversity in North-East Africa and examine for genomic variation specific to Sudan, possibly related to the persistence of trachoma in surveyed communities."( Alkhidir, AAI; Breuer, J; El Hussain, KMK; Elemam, AE; Elhag, WI; Holland, MJ; Ournasseir, MEH; Pickering, H; Williams, CA, 2019)
"trachomatis isolates."( Alkhidir, AAI; Breuer, J; El Hussain, KMK; Elemam, AE; Elhag, WI; Holland, MJ; Ournasseir, MEH; Pickering, H; Williams, CA, 2019)
"trachomatis suggests minimal transmission between and slow diversification within trachoma-endemic communities."( Alkhidir, AAI; Breuer, J; El Hussain, KMK; Elemam, AE; Elhag, WI; Holland, MJ; Ournasseir, MEH; Pickering, H; Williams, CA, 2019)
"Trachoma is the leading infectious cause of blindness globally."( Altherr, FM; Astale, T; Ayenew, G; Callahan, EK; Chanyalew, M; Gashaw, B; Gessese, D; Melak, B; Nash, SD; Nute, AW; Sata, E; Stewart, AEP; Tadesse, Z; Waller, LA; Zerihun, M, 2019)
"Trachoma is a contagious infection of the eye by specific strains of the bacteria Chlamydia trachomatis."( Bekuma, TT; Desalegn Waktole, Z; Gaddisa, S; Markos Cafo, J; Mosisa Kebebew, G; Wirtu, D, 2019)
"trachomatis DNA."( Gaydos, C; Mkocha, H; Munoz, B; Nanji, AA; Quinn, TC; West, SK, 2019)
"trachomatis DNA."( Gaydos, C; Mkocha, H; Munoz, B; Nanji, AA; Quinn, TC; West, SK, 2019)
"C."( Gaydos, C; Mkocha, H; Munoz, B; Nanji, AA; Quinn, TC; West, SK, 2019)
"trachomatis infection in nonhuman primates."( Chen, C; Chen, H; Chen, L; Li, C; Lu, C; Peng, B; Sun, Z; Zhong, G; Zhu, C, 2020)
"trachomatis organisms, and analyzed by C."( Chen, C; Chen, H; Chen, L; Li, C; Lu, C; Peng, B; Sun, Z; Zhong, G; Zhu, C, 2020)
"trachomatis antigens."( Chen, C; Chen, H; Chen, L; Li, C; Lu, C; Peng, B; Sun, Z; Zhong, G; Zhu, C, 2020)
"Trachoma is a contagious infection of the eye."( Gebreyesus, A; Reda, G; Yemane, D, 2020)
"trachomatis infection data were collected for 1613 children aged 0-9 years in 12 Senegalese villages as part of a cross-sectional trachoma prevalence study."( Andreasen, AA; Bailey, RL; Butcher, RMR; Harding-Esch, EM; Holland, MJ; Mabey, DCW; Molina-Gonzalez, S; Sarr, B; Schémann, JF; Sissoko, M, 2020)
"trachomatis (primary outcome), TF and other clinical signs of trachoma, and serologic markers of trachoma after 3 years."( Amza, A; Arnold, BF; Arzika, AM; Austin, A; Kadri, B; Lebas, E; Lietman, TM; Nassirou, B; Nyatigo, F; Oldenburg, CE, 2021)
"trachomatis infection would benefit from a simple blood test that could be integrated with other public health programs."( Bethea, D; Callahan, EK; Chernet, A; Gwyn, S; Haile, M; Laurent, C; Martin, DL; Nash, SD; Nute, AW; Sata, E; Tadesse, Z; Zeru, T, 2021)
"Ocular surface C."( Ayele, B; Chen, C; Doan, T; Emerson, PM; Gebre, T; Hinterwirth, A; Keenan, JD; Lietman, TM; Porco, TC; Ruder, K; Zerihun, M; Zhong, L; Zhou, Z, 2022)
"trachomatis and 3 Neisseria species in communities treated with azithromycin."( Ayele, B; Chen, C; Doan, T; Emerson, PM; Gebre, T; Hinterwirth, A; Keenan, JD; Lietman, TM; Porco, TC; Ruder, K; Zerihun, M; Zhong, L; Zhou, Z, 2022)
"The C."( Astale, T; Ayele, Z; Chernet, A; Gessese, D; Haile, M; Jensen, KA; Kelly Callahan, E; Melak, B; Nash, SD; Nute, AW; Sata, E; Tadesse, Z; Zerihun, M; Zeru, T, 2021)
"Trachoma is an infectious disease characterized by repeated exposures to Chlamydia trachomatis (Ct) that may ultimately lead to blindness."( Aragie, S; Arnold, BF; Gwyn, S; Haile, M; Keenan, JD; Lietman, TM; Martin, DL; Nash, SD; Sturrock, HJW; Tadesse, Z; Tedijanto, C; Wittberg, DM; Zeru, T, 2022)
"trachomatis prevalence was 34."( Apadinuwe, SC; Bakhtiari, A; Butcher, R; Cama, A; Catlett, B; Cunningham, P; Garabwan, C; Gwyn, S; Harding-Esch, EM; Hillgrove, T; Kaldor, JM; Lambert, SB; Lynch, KD; Martin, D; Solomon, AW; Starr, M; Vaz Nery, S; Ware, RS; Webster, S, 2022)
"trachomatis transmission among children present a high risk of ocular damage due to trachoma."( Apadinuwe, SC; Bakhtiari, A; Butcher, R; Cama, A; Catlett, B; Cunningham, P; Garabwan, C; Gwyn, S; Harding-Esch, EM; Hillgrove, T; Kaldor, JM; Lambert, SB; Lynch, KD; Martin, D; Solomon, AW; Starr, M; Vaz Nery, S; Ware, RS; Webster, S, 2022)
"Trachoma is a predominant neglected disease in Ethiopia, and there is a 40."( Adem, A; Bekele, D; Feyisa, T; Nugusu, F; Tura, B, 2022)
"Trachoma is the leading infectious cause of blindness."( Abdala, M; Al-Khateeb, TQ; Amza, A; Baayenda, G; Badiane, MD; Bakhtiari, A; Batcho, WE; Bella, AL; Bio Issifou, AA; Bobo Barkesa, S; Bucumi, V; Elshafie, BE; Epee, E; Freeman, MC; Gower, EW; Harding-Esch, EM; Kabona, GE; Kadri, B; Kaitaba, O; Kalua, KM; Keil, AP; Masika, MP; Massangaie, ME; Minnih, AO; Mpyet, CD; Mwale, C; Nassirou, B; Olobio, N; Sanha, S; Seife Gebretsadik, F; Simon, A; Solomon, AW; Sullivan, KM; Westreich, D, 2023)
"Trachoma is a leading cause of preventable blindness."( Hussen, MS; Munaw, MB; Shobiso, MG; Tilahun, MM, 2023)
"trachomatis antigen Pgp3, seroprevalence in 1-9-year-olds was 30."( Bakhtiari, A; Butcher, R; Cama, A; Goodhew, EB; Guagliardo, SAJ; Gwyn, SE; Harding-Esch, EM; Jimenez, C; Martin, DL; Mpyet, CD; Solomon, AW; Taoaba, R; Tekeraoi, R; Tun, K; Wickens, K, 2023)
"Trachoma is the chief cause of preventable blindness worldwide and has been earmarked for elimination as a public health problem by 2030."( Asebe, HA; Asgedom, YS; Asmare, ZA; Fente, BM; Kase, BF; Lombebo, AA; Mare, KU; Sabo, KG; Seifu, BL; Shibeshi, AH; Tebeje, TM; Teshale, AB, 2023)
"Trachoma is a neglected tropical disease caused by ocular infection with Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result in scarring, trichiasis and blindness."( Bailey, R; Barton, A; Burton, MJ; Derrick, T; Faal, N; Harte, A; Holland, MJ; Joof, H; Mabey, DC; Mafuru, E; Makalo, P; Malissa, A; Massae, P; Mtuy, T; Pickering, H; Ramadhani, A; Sillah, A, 2023)
"trachomatis infection, possibly due to a positive feedback loop inducing immune activation."( Bailey, R; Barton, A; Burton, MJ; Derrick, T; Faal, N; Harte, A; Holland, MJ; Joof, H; Mabey, DC; Mafuru, E; Makalo, P; Malissa, A; Massae, P; Mtuy, T; Pickering, H; Ramadhani, A; Sillah, A, 2023)
"Trachoma is the world's most frequent cause of blindness from an infectious agent."( Downs, P; Jeyam, A; Kebede, F; Selby, R; Tate, A, 2023)

Context

ExcerptReference
"Trachoma has become almost exclusively an imported disease."( Benes, C; Haicl, P; Vanista, J, 1993)
"Although trachoma has either decreased or disappeared in many Third World countries through socio economic development during the past forty years, it remains a major problem among the poorest communities, which is often ignored by decision-makers when setting priorities."( Mariotti, SP; Négrel, AD; Thylefors, B, 1997)
"Trachoma has been endemic in The Gambia for decades but national surveys indicate that the prevalence is falling."( Aryee, EA; Bailey, RL; Edwards, T; Harding-Esch, EM; Holland, MJ; Mabey, DC; Sarr-Sissoho, I; Sillah, A; Snell, P, 2008)
"Trachoma has been known since pre-Pharaonic times and this infectious cause of blindness is targeted by the World Health Organization (WHO) for elimination by 2020."( Taylor, HR, 2009)
"Trachoma has been one of the most blinding diseases in the history of ophthalmology."( Feibel, RM, 2011)
"Trachoma has not been eliminated from Car-Nicobar Island in accordance to 'Global Elimination of Trachoma, 2020' guidelines."( Azad, R; Gupta, N; Kalaivani, M; Krishnan, S; Malhotra, S; Satpathy, G; Shah, A; Vashist, P, 2016)

Actions

ExcerptReference
"Although trachoma impact surveys have a nontrivial cost, they generally save money, providing EUs have > 50,000 inhabitants, the continuation rate is not excessive, and they generate reliable data."( Bakhtiari, A; Bangert, M; Brady, MA; Fitzpatrick, C; Harding-Esch, EM; Hooper, PJ; Jones, I; Kabona, G; Kello, AB; Malecela, MN; Millar, T; Mosher, AW; Mwingira, UJ; Ngondi, JM; Nshala, A; Renneker, K; Rotondo, LA; Solomon, AW; Stelmach, R, 2020)

Treatment

ExcerptReference
"A controlled chemotherapy trial of trachoma was carried out in a Tunisian oasis among schoolchildren with active disease."( Daghfous, T; Dawson, CR; Hoshiwara, I; Messadi, M; Schachter, J; Vastine, DW, 1975)
"The detection of Chlamydia trachomatis by direct immunofluorescence (IF) using a conjugated monoclonal antibody to its principal outer membrane protein was compared with isolation in cycloheximide-treated McCoy cells."( Booth-Mason, S; Mabey, DC, 1986)
"In communities with endemic blinding trachoma, mass (or "blanket") treatment with a topically applied tetracycline derivative is a standard control measure."( Briones, O; Chadgrah, F; Daghfous, T; Dawson, CR; Hoshiwara, T; Messadi, M; Schachter, J; Triki, F; Whitcher, J; Yoneda, C, 1981)
"In patients with scarring trachoma, the treatment did not significantly reduce the inclusion count."( Babikir, HE; Elhassan, AE; Fröman, G; Mahmoud, EA; Mårdh, PA, 1994)
"In order to optimize the trachoma treatment duration, we carried out a prospective study to observe the disease course over a long period of treatment by a 1% oxytetracycline (chlorhydrate) suspension."( Bagayogo, C; Castan, R; Huguet, P; Peyramaure, F; Resnikoff, S, 1994)
"Clinical trachoma, and microbiologic evidence of chlamydia, were assessed at baseline, 2 and 4 weeks into mass treatment, and 4 weeks after treatment stopped."( Bobo, L; Lynch, M; Mkocha, H; Mmbaga, BB; Muñoz, B; Quinn, TC; Viscidi, R; West, S, 1993)
"Risk factors for constant, severe trachoma were identified in a group of children enrolled in a longitudinal study in Kongwa, Tanzania, where villages were randomized in a clinical trial of mass treatment and a behavior modification campaign."( Kayongoya, A; Lynch, M; Mmbaga, BB; Muñoz, B; Taylor, HR; West, SK, 1996)
"Risk factors for constant, severe trachoma were identified in a group of children enrolled in a longitudinal study in Kongwa, Tanzania, where villages were randomized in a clinical trial of mass treatment and a behavior modification campaign."( Kayongoya, A; Lynch, M; Mmbaga, BB; Muñoz, B; Taylor, HR; West, SK, 1996)
"For children with trachoma, rates of carriage of pneumococci immediately before treatment with azithromycin and 2-3 weeks, 2 months, and 6 months after treatment were 68% (54 of 79), 29% (11 of 38), 78% (29 of 37), and 87% (34 of 39), respectively."( Currie, BJ; Gratten, M; Laming, AC; Leach, AJ; Mathews, JD; Mayo, M; Shelby-James, TM, 1997)
"Programmes to prevent blindness due to trachoma are based on community-wide treatment with topical tetracycline."( Bailey, R; Bobo, L; Dawson, CR; Faal, H; Mabey, D; Mkocha, H; Quinn, TC; Sallam, S; Schachter, J; Sheta, A; Vitale, S; West, SK, 1999)
"Change in trachoma status was determined from baseline to one month post treatment."( Lynch, M; O'Connor, J; Vitale, S; West, S, 1999)
"Azithromycin treatment for trachoma had favorable short term effects on childhood morbidity in rural Gambian villages, particularly in the high malaria transmission season, and adverse effects were not a problem."( Bailey, R; Glasgow, KW; Mabey, DC; Sadiq, ST; Whitty, CJ, 1999)
"Repeated mass treatment of trachoma endemic areas with oral azithromycin will have an effect on bacterial flora."( Cevallos, V; Chern, KC; Chern, L; Dhami, HL; Lietman, TM; Shrestha, SK; Tiwari, P; Whitcher, JP, 1999)
"Community control of trachoma as a blinding disease is based on the SAFE strategy of Surgery, Antibiotic therapy, Facial cleanliness and Environmental improvement."( Bailey, RL; Cairncross, S; Emerson, PM; Mabey, DC, 2000)
"To ascertain the prevalence of acute trachoma as a supposed endemic disease among infants in the Saharan refugee camps of Tindouf (Algeria) and to evaluate the efficacy of treatment with a single dose of azithromycin."( Alió, JL; Ferrer, C; Javaloy, J; Vidal, MT, 2003)
"National programs for trachoma control are implementing mass treatment programs in which azithromycin is used as part of the control strategy."( Bailey, R; Barwick, R; Burton, M; Foster, A; Mabey, D; Muñoz, B; Solomon, AW; West, SK; Zingeser, J, 2003)
"Clinically active trachoma is not always a reliable marker of infection, particularly in teenagers and after treatment."( Bassem, A; Bird, M; Dawson, CR; Lietman, TM; Miao, Y; Osman, A; Schachter, JS; Shama, A, 2003)
"Data were gathered on risk factors for trachoma, socioeconomic status, and the perceived effect of the initial azithromycin treatment."( Frick, KD; Lynch, M; Mkocha, HA; Munoz, B; West, S, 2003)
"As those at greatest risk of active trachoma indicated the lowest willingness to pay, imposing a cost recovery fee for azithromycin treatment would likely reduce coverage and could prevent control of the disease at the community level."( Frick, KD; Lynch, M; Mkocha, HA; Munoz, B; West, S, 2003)
"Although trachomatous blindness is untreatable, it is eminently possible to prevent and the World Health Organization promotes the use of the SAFE strategy (surgery to treat end-stage disease, antibiotics to reduce the reservoir of infection, facial cleanliness, and environmental improvement to reduce transmission of C trachomatis) for this purpose."( Buchan, J; Foster, A; Kuper, H; Mabey, D; Solomon, AW; Zondervan, M, 2003)
"Even if the number of cases of trachoma in the world is now 6-fold lower than twenty years ago, still 83 millions of patients are affected by active trachoma, leading to the estimation that 490 millions of people should be treated in a curative or a preventive way."( Labetoulle, M; Raymond, J, 2005)
"In a community of Tanzania where trachoma is endemic, we cultured conjunctival swabs from all residents who had active trachoma and were PCR positive for ocular Chlamydia trachomatis, both before (43 isolates) and 2 months after (9 isolates) mass antibiotic treatment."( Foster, A; Mabey, DC; Massae, PA; Mohammed, Z; Peeling, RW; Shao, JF; Solomon, AW, 2005)
"Active trachoma and swab samples of the conjunctiva were assessed at baseline and at 2, 6, 12, and 18 months after treatment."( Broman, AT; Duncan, DD; Munoz, B; Shum, K; West, SK, 2006)
"Infection with C trachomatis did not differ between groups at 6 months post-treatment (9%vs 7%, p=0."( Bailey, R; Emerson, PM; Mabey, D; McHiwa, W; Mkocha, H; Munoz, B; West, SK, 2006)
"In active trachoma, azithromycin eye drops twice daily for 2 or 3 days are as efficient as the WHO's reference treatment and represent an innovative alternative to oral azithromycin."( Afghani, T; Bourcier, T; Cochereau, I; Delval, L; Goepogui, A; Goldschmidt, P; Pouliquen, P; Robert, PY, 2007)
"In mesoendemic trachoma areas, targeted treatment to all children under 11 years of age and women between 15 and 50 (strategy II) was as effective as indiscriminate mass distribution (strategy I) and more effective than treatment targeted to inhabitants of households where at least one child had active trachoma diagnosed (strategy III)."( Dembele, M; Diallo, I; Guinot, C; Malvy, D; Schémann, JF; Traore, A; Traore, L; Vinard, P; Zefack, G, 2007)
"Active trachoma was found in a high percentage of children in Al-Jawf, Mareb and Shabwah governorates and the SAFE strategy (Surgery, Antibiotic treatment, Facial cleanliness, Environmental improvement) should be directed toward these governorates."( Al-Jabal, MH; Al-Khatib, TK; Al-Kuhlany, AM; Hamid, AS; Raja'a, YA, 2006)
"A stochastic model of trachoma transmission was constructed, using the parameters with the maximum likelihood of obtaining results observed from studies in Tanzania (with 16% infection in children pre-treatment), The Gambia (9%), and Ethiopia (64%)."( Bailey, RL; Burton, MJ; Harding-Esch, E; Holland, MJ; Keenan, JD; Lietman, TM; Mabey, D; Porco, TC; Ray, KJ; Solomon, AW, 2009)
"Clinical trachoma activity in children aged 1 to 5 years decreased from 78% and 83% in the 2 villages before treatment to 17% and 24% at 42 months."( Alemayehu, W; Biebesheimer, JB; Gaynor, BD; Hong, KC; House, J; Keenan, J; Lakew, T; Lietman, TM; Moncada, J; Rogér, A; Schachter, J; Zhou, Z, 2009)
"In a region with hyperendemic trachoma, conjunctival examination was a useful indicator of the prevalence of chlamydial infection before treatments, less useful during mass treatments, but regained utility by one year after treatments had stopped."( Acharya, NR; Alemayehu, W; Gaynor, BD; House, JI; Keenan, JD; Lakew, T; Lietman, TM; Melese, M; Porco, TC; Ray, KJ; Whitcher, JP; Yi, E; Zhou, Z, 2010)
"Mass treatment to trachoma endemic communities is a critical part of the World Health Organization SAFE strategy."( Bailey, RL; Edwards, T; Harding-Esch, EM; Mabey, DC; Mkocha, H; Munoz, B; Sillah, A; Ssemanda, EN; Stare, D; West, SK, 2010)
"Active trachoma mass treatment with azithromycin 1."( Amza, A; Bella-Assumpta, L; Bensaid, P; Einterz, E; Goldschmidt, P; Huguet, P; Olmiere, C, 2010)
"As part of its strategy to eliminate trachoma, the World Health Organization recommends annual mass antibiotic treatment for at least 3 years with an 80% population coverage target."( Bailey, R; Gaydos, C; Harding-Esch, E; Holland, M; Mabey, D; Munoz, B; Stare, D; West, S, 2011)
"Therapy for trachoma had barely advanced from the measures used by the ancient Egyptian, Greek, and Roman physicians."( Feibel, RM, 2011)
"We determined the prevalence of trachoma and infection with Chlamydia trachomatis in communities after 3-7 years of annual mass treatment in Tanzania."( Gaydos, CA; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2011)
"Country programs in trachoma-endemic regions must realistically expect that several years of annual mass treatment may be necessary to eliminate trachoma."( Gaydos, CA; Mkocha, H; Munoz, B; Quinn, TC; West, SK, 2011)
"Mass treatment with azithromycin for trachoma endemic communities typically excludes infants under age 6 months, whose parents are provided with tubes of tetracycline to administer daily over 4 to 6 weeks."( Gaydos, C; Mkocha, H; Munoz, B; Quinn, TC; Stare, D; West, SK, 2011)
"The clinical signs of active trachoma are often present in the absence of ocular Chlamydia trachomatis infection in low prevalence and mass treated settings."( Andreasen, AA; Bailey, RL; Edwards, T; Harding, EF; Harding-Esch, EM; Holland, MJ; Mabey, DC; Molina, S; Roberts, Ch; Sarr, B; Sarr, I; Schémann, JF; Sillah, A, 2011)
"Twelve trachoma-hyperendemic communities were treated with 3 annual mass azithromycin distributions."( Ayele, B; Emerson, PM; Gaynor, BD; Gebre, T; Keenan, JD; Lietman, TM; McCulloch, CE; Moncada, J; Porco, TC; Schachter, J; Stoller, NE; Zhou, Z, 2012)
"Although trachoma control programs frequently use the World Health Organization (WHO) simplified grading system for trachoma to monitor the clinical response after repeated mass azithromycin treatments, the programmatic relevance of this evaluation after multiple rounds of antibiotic treatments is unclear."( Ayele, B; Emerson, PM; Gaynor, BD; Gebre, T; Keenan, JD; Lietman, TM; McCulloch, CE; Moncada, J; Porco, TC; Schachter, J; See, CW; Stoller, NE, 2012)
"Mass treatment for trachoma using a single dose of oral azithromycin was provided in 4 of the 8 communities where trachoma prevalence was ."( Coles, CL; Levens, J; Mkocha, H; Munoz, B; Seidman, JC; West, S, 2012)
"In areas with highly prevalent trachoma treated with multiple rounds of mass azithromycin, trachoma programs could consider continuing mass azithromycin treatments in households that have missed prior mass antibiotic treatments, in households with clinically active trachoma, and in larger communities."( Ayele, B; Emerson, PM; Gaynor, BD; Gebre, T; House, JI; Keenan, JD; Moncada, J; Porco, TC; Schachter, J; Stoller, NE; Zhou, Z, 2011)
"For children with severe trachoma, a randomized controlled trial of 2-day versus 1-day treatment may be warranted."( Campbell, JP; Mkocha, H; Munoz, B; West, SK, 2012)
"In children with trachomatous inflammation, 3-day treatment with azithromycin 1."( Garnock-Jones, KP, 2012)
"Though trachoma can be treated with antibiotics (active trachoma) or surgery (trachomatous trichiasis), it is still endemic in most parts of Ethiopia."( Ejigu, M; Gelaw, Y; Ilako, DR; Kariuki, MM, 2013)
"To eliminate blinding trachoma, the World Health Organization emphasizes implementing the SAFE strategy, which includes annual mass drug administration (MDA) with azithromycin to the whole population of endemic districts."( Admassu Ayele, F; Adugna, M; Ayalew, F; Cromwell, EA; Damte, M; Emerson, PM; Endashaw, T; Gebre, T; Gebregzabher, T; Gessesse, D; Haileysus, G; Karie, A; King, JD; King, MR; Melak, B; Mosher, AW; Mulualem, A; Ngondi, JM; Odermatt, P; Stoller, NE; Tadesse, Z; Teferi, T; Utzinger, J; Worku, A; Zerihun, M, 2014)
"Antibody responses to trachoma antigens declined significantly six months after drug treatment for most age groups."( Dize, L; Gaydos, C; Goodhew, EB; Lammie, PJ; Martin, DL; Mkocha, H; Morgan, SM; Munoz, B; Switzer, AJ; West, SK; Wiegand, RE, 2014)
"Mass administration of azithromycin for trachoma has been shown to reduce malarial parasitemia."( Ackley, SF; Amza, A; Gao, D; Kadri, B; Lietman, TM; Liu, F; Nassirou, B; Porco, TC; Sippl-Swezey, N, 2014)
"In 2009, trachoma prevalence was 14%, but through screening, treatment and health promotion, rates had fallen to 4% in 2012."( Anjou, MD; Atkinson, JR; Boudville, AI; Lange, FD; Stanford, EE, 2014)
"We used the International Trachoma Initiative's prevalence and treatment database."( Emerson, PM; Gelderblom, HC; Haddad, D; Jimenez, V; Mann Flueckiger, R, 2015)
"Both yaws and trachoma--which is earmarked for elimination by 2020 using a strategy that includes mass treatment with 20 mg/kg azithromycin--are endemic in the Pacific, raising the possibility of an integrated approach to disease control."( Bottomley, C; Chi, KH; Dalipanda, T; Kilua, G; Mabey, DC; Marks, M; Pillay, A; Puiahi, E; Sokana, O; Solomon, AW; Vahi, V, 2015)
"Though trachoma can be treated with antibiotic it is still endemic in most part of Ethiopia."( Berhe, R; Gedefaw, M; Nigusie, A, 2015)
"Mass drug administration (MDA) for trachoma control is administered based on the population prevalence of the clinical sign of trachomatis inflammation - follicular (TF)."( Bailey, RL; Cassama, E; Derrick, T; Holland, MJ; Last, AR; Markham-David, R; Marks, M; Nabicassa, M, 2016)
"Despite some success in controlling trachoma with repeated mass drug administration (MDA), some hyperendemic regions are not responding as fast as anticipated."( Burton, MJ; Gambhir, M; Pinsent, A, 2016)
"We estimated the change in trachoma prevalence between sequential pairs of years and across multiple years according to treatment strategy using random-effects meta-analyses."( Cowling, C; Hayen, A; Kaldor, JM; Lambert, S; Liu, B; Mak, DB; Taylor, H; Watt, G, 2016)
"Prevention of Trachoma, the leading cause of infectious blindness, requires community treatment assistants (CTAs) to perform mass drug administration (MDA) of azithromycin."( Jenson, A; Mkocha, H; Munoz, B; Roter, DL; West, S, 2018)
"The antibiotic treatment of people with trachoma helps to prevent transmission the disease in a community."( Asfaw, S; Gebregergs, GB; Gigar, G; Kidane, A; Meresa, B; Mitiku, M; Mulugeta, A; Yemane, D, 2018)
"We undertook population-based trachoma surveys in 18 evaluation units of the 8 treated districts, at least 6 months after the MDA."( Bailey, RL; Bakhtiari, A; Chinyanya, D; Chisambi, A; Emerson, PM; Kalua, K; Masika, M; Solomon, AW; Willis, R, 2018)
"Mass drug administration (MDA) for trachoma control using azithromycin has generated concern for the development of resistant organisms."( Ansah, D; Bloch, EM; Coles, CL; Lietman, T; Munoz, B; Weaver, J; West, SK, 2019)
"Regions with low prevalence of active trachoma may have little if any ocular chlamydia, and, thus, may not benefit from azithromycin treatment."( Amza, A; Aragie, S; de Hostos Barth, A; Godwin, WW; Landskroner, E; Lietman, TM; Mahmud, H; O'Brien, KS; Oldenburg, CE, 2021)
"Programs to eliminate trachoma as a public health problem use prevalence of the clinical sign trachomatous inflammation-follicular (TF) in 1- to 9-year-olds in endemic districts to make decisions to begin or end mass drug administration with azithromycin."( Bethea, D; Callahan, EK; Chernet, A; Gwyn, S; Haile, M; Laurent, C; Martin, DL; Nash, SD; Nute, AW; Sata, E; Tadesse, Z; Zeru, T, 2021)
"The International Trachoma Initiative (ITI) provides azithromycin for mass drug administration (MDA) to eliminate trachoma as a public health problem."( Addiss, DG; Alemu, M; Ciciriello, AM; Emerson, PM; Gebre, T; Hooper, PJ; Kebede, F; Kiflu, G; LaCon, G; Seid, M; Seife, F; Sormolo, MJ; Tadesse, G; Teferi, T; West, SK, 2022)
"Persistent and recrudescent trachoma in evaluation units (EUs) were examined for whether AZM MDA in EUs was accompanied by IVM MDA, and whether co-administration was associated with greater likelihood of trachoma control."( Downs, P; Jeyam, A; Kebede, F; Selby, R; Tate, A, 2023)

Research

Studies (1,017)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990528 (51.92)23.3326
1990's68 (6.69)12.5806
2000's142 (13.96)18.1394
2010's208 (20.45)28.8240
2020's71 (6.98)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetone0low10
citric acid, anhydrous0low30
chlorine0medium11
salicylic acid0low10
formaldehyde0low40
glycerol0low10
iodine0low50
niacinamide0low10
nitrates0low10
4-aminobenzoic acid0low10
phenol0low10
mercaptoethanol0low10
albendazole0medium11
amantadine0low10
berberine0medium52
chloroquine0low20
dapsone0low10
diphenhydramine0low10
erythrosine0low50
flumazenil0low10
gentamicin0low30
guaifenesin0low30
guanethidine0low10
ethidium0low10
2-propanol0low70
metronidazole0medium11
norfloxacin0low10
ofloxacin0medium11
pentamidine0low10
practolol0low10
sulfadiazine0medium51
sodium iodide0low10
stearic acid0low10
sulfacetamide0medium81
sulfadimethoxine0medium21
sulfamerazine0medium31
sulfamethazine0medium21
sulfamethoxazole0medium11
sulfamethoxypyridazine0medium141
sulfanilamide0low530
sulfaphenazole0low60
sulfisoxazole0medium126
trimethoprim0medium11
zinc chloride0medium11
prednisolone0low10
cephaloridine0low10
thymidine0low20
prednisone0low10
penicillin g0low20
idoxuridine0low40
pilocarpine0low10
chloramphenicol0medium342
lysine0low20
sucrose0low10
cephalothin0low10
kanamycin a0low10
carbostyril0low30
methicillin0low10
methylene blue0medium51
leucine0low10
cycloheximide0low20
cycloserine0low20
tryptophan0low10
trichloroacetic acid0low20
phencyclidine0low50
tromethamine0low10
methylprednisolone0low10
framycetin0medium81
neoprontosil0low10
sodium cyanide0low10
sulfalene0medium11
acridines0low20
pyrazines0low20
hydrazine0low10
betamethasone0low20
fluorometholone0medium11
hydantoins0low10
emetine0low10
lucanthone hydrochloride0low10
erythromycin0medium386
deoxycytidine0low10
vancomycin0low10
sulfadoxine0low20
etridiazol0low20
streptomycin0low80
dihydrostreptomycin sulfate0low10
manganese0low10
silver0low10
technetium0low10
silver nitrate0low60
fluorine0low10
chlorine0low10
trolamine salicylate0low10
cromolyn sodium0medium11
fluorides0low20
4-methoxyamphetamine0low10
transferrin0low10
sodium azide0low10
azides0low10
amoxicillin0low10
tobramycin0low10
permethrin0medium11
decamethrin0low10
propiconazole0low50
metsulfuron methyl0low60
octyl glucoside0low10
glucose, (beta-d)-isomer0low20
propamidine isethionate0low10
nsc-1727550low20
glucuronic acid0low10
edotreotide0medium11
angiotensin ii0medium11
cortisone0low140
trimethoprim, sulfamethoxazole drug combination0low10
povidone-iodine0medium21
glycogen0low50
elastin0low10
inositol 3-phosphate0low60
erythromycin estolate0low20
erythromycin ethylsuccinate0medium21
retinol0low70
zithromax0medium27479
dactinomycin0low10
arsphenamine0low10
glycosides0low10
allylthiourea0low10
thiourea0low10
fusidic acid0low10
quinine0low10
alpha-chymotrypsin0low10
benzyl cinnamate0low10
travoprost0low10
hydrocortisone valerate0low20
phenylephrine hydrochloride0low40
morphine0low20
cloprostenol0low10
aluminum0low10
ethylmorphine0low20
arsenic0low10
nitrofurazone0low10
cysteine0low10
picloxydine0medium11
ammonium sulfate0low10
radium0low30
phtiobuzone0low10
loa0low10
chlorhexidine0medium21
mocetinostat0low10
carbomycin0low20
nystatin a10low10
dextrothyroxine0medium62
acid phosphatase0low20
erythrosine0low20
cromolyn sodium0low20
gramicidin a0low10
tannins0low70
cellulose0low40
tryparsamide0low10
sodium pertechnetate tc 99m0low10
neoarsphenamine0low10
glycolipids0low20
interleukin-80low30
colistin0low10
methylcellulose0low30
heparitin sulfate0low10
novobiocin0low10
tetracycline0medium12134
chlortetracycline0medium652
oxytetracycline, anhydrous0medium406
minocycline0medium31
salicylates0low10
demeclocycline0low20
dibiomycin0low30
lymecycline0low20
transforming growth factor beta0low20
pyrethrins0low10
rome0low20
agar0low10
hyaluronoglucosaminidase0low30
cyclosporine0low20
lactoferrin0low10
muramidase0low60
exudates0low30
folic acid0low10
rifampin0medium166
alcian blue0low10
eye0medium652

Protein Targets (1,135)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit140014
RAR-related orphan receptor gamma290029
GLI family zinc finger 3430043
AR protein470047
aldehyde dehydrogenase 1 family, member A1290029
retinoic acid nuclear receptor alpha variant 1380038
retinoid X nuclear receptor alpha350035
estrogen nuclear receptor alpha620062
peroxisome proliferator-activated receptor delta210021
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a270027
activating transcription factor 6160016
v-jun sarcoma virus 17 oncogene homolog (avian)190019
Histone H2A.x160016
thyroid hormone receptor beta isoform a190019
heat shock protein beta-1140014
nuclear factor erythroid 2-related factor 2 isoform 1340034
lamin isoform A-delta10250025
Voltage-dependent calcium channel gamma-2 subunit190019
Glutamate receptor 2190019
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE220022
Genome polyprotein 0011
USP1 protein, partial150015
thyroid stimulating hormone receptor270027
glucocorticoid receptor [Homo sapiens]410041
chromobox protein homolog 1230023
transcriptional regulator ERG isoform 38008
geminin360036
Polyphenol oxidase 20204
Cellular tumor antigen p53290029
Thiopurine S-methyltransferase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Cytochrome P450 1B10404
Dihydropteroate synthase 0011
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 2A0516
5-hydroxytryptamine receptor 1A0325
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0314
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0011
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
TDP1 protein360036
estrogen-related nuclear receptor alpha420042
thyroid hormone receptor beta isoform 2310031
Chain A, Ferritin light chain9009
thioredoxin reductase200020
Microtubule-associated protein tau140014
Smad37007
alpha-galactosidase3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
flap endonuclease 1150015
DNA polymerase iota isoform a (long)160016
DNA topoisomerase 2-alpha0102
Acetylcholinesterase0404
Chain A, Beta-lactamase100010
Luciferase110011
glp-1 receptor, partial120012
ATAD5 protein, partial7007
Fumarate hydratase7007
caspase 7, apoptosis-related cysteine protease6006
nuclear receptor subfamily 1, group I, member 3290029
progesterone receptor220022
farnesoid X nuclear receptor250025
pregnane X nuclear receptor360036
polyprotein7007
67.9K protein9009
peroxisome proliferator activated receptor gamma270027
vitamin D (1,25- dihydroxyvitamin D3) receptor240024
caspase-36006
IDH19009
euchromatic histone-lysine N-methyltransferase 2300030
aryl hydrocarbon receptor220022
nuclear receptor subfamily 1, group I, member 28008
cellular tumor antigen p53 isoform a5005
nuclear factor erythroid 2-related factor 2 isoform 2130013
histone deacetylase 9 isoform 33003
mitogen-activated protein kinase 18008
urokinase-type plasminogen activator precursor9009
plasminogen precursor9009
urokinase plasminogen activator surface receptor precursor9009
Vif0001
peripheral myelin protein 22120012
survival motor neuron protein isoform d140014
muscleblind-like protein 1 isoform 17007
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
neuropeptide S receptor isoform A5005
ATP-binding cassette sub-family C member 3027027
Multidrug resistance-associated protein 4027028
Bile salt export pump047047
Interferon beta220022
Integrin beta-34004
Integrin alpha-IIb4004
Methionine aminopeptidase0101
Fatty-acid amide hydrolase 10202
Inositol monophosphatase 14004
Canalicular multispecific organic anion transporter 1026026
ATPase family AAA domain-containing protein 5130013
Ataxin-2150015
bromodomain adjacent to zinc finger domain 2B8008
vitamin D3 receptor isoform VDRA150015
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
Guanine nucleotide-binding protein G5005
acetylcholinesterase150015
NFKB1 protein, partial3003
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 48008
EWS/FLI fusion protein140014
putative alpha-glucosidase1001
histone acetyltransferase KAT2A isoform 1110011
Solute carrier family 22 member 20406
Solute carrier family 22 member 1 0607
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0416
Spike glycoprotein151319
Glutamate receptor ionotropic, NMDA 2A 0416
Glutamate receptor ionotropic, NMDA 2B0416
Glutamate receptor ionotropic, NMDA 2C0417
Glutamate receptor ionotropic, NMDA 10404
Glutamate receptor ionotropic, NMDA 2A0404
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 2D0416
Solute carrier family 22 member 10405
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0416
Multidrug and toxin extrusion protein 10606
Solute carrier family 22 member 20404
Glutamate receptor ionotropic, NMDA 3A0416
ATP-dependent phosphofructokinase100010
Chain A, 2-oxoglutarate Oxygenase100010
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0004
apical membrane antigen 1, AMA13003
Beta-lactamase 0003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
DNA polymerase eta isoform 14004
DNA polymerase kappa isoform 1110011
Bile salt export pump012012
Beta-lactamase SHV-10003
Beta-lactamase SHV-10004
Cytochrome P450 2C9 010010
Beta-lactamase0004
Kappa-type opioid receptor0205
Solute carrier family 15 member 10505
Solute carrier family 15 member 10101
Cytochrome P450 2J20808
B2 metallo-beta-lactamase 0004
Solute carrier family 15 member 20404
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 15 member 20505
Beta-lactamase 0003
Beta-lactamase 0003
glucocerebrosidase4004
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0224
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Carbonic anhydrase 1015017
Carbonic anhydrase 2017221
Carbonic anhydrase 409010
Carbonic anhydrase0809
Carbonic anhydrase 150708
cytochrome P450 family 3 subfamily A polypeptide 4230023
G130013
thyroid stimulating hormone receptor160016
potassium voltage-gated channel subfamily H member 2 isoform d8008
17beta-hydroxysteroid dehydrogenase0101
HLA class I histocompatibility antigen, B alpha chain 130013
Inositol hexakisphosphate kinase 1130013
cytochrome P450 2C9, partial130013
Chain A, Putative fructose-1,6-bisphosphate aldolase9009
PPM1D protein9009
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)110011
cytochrome P450 2D6 isoform 15005
cytochrome P450 3A4 isoform 1150015
Gamma-aminobutyric acid receptor subunit pi154121
Telomerase reverse transcriptase0101
Acetylcholinesterase0404
Lysine-specific histone demethylase 1A0101
Neuraminidase0101
Neuraminidase0101
Cholinesterase0202
Gamma-aminobutyric acid receptor subunit beta-1154121
Tyrosine-protein phosphatase non-receptor type 10305
Gamma-aminobutyric acid receptor subunit delta154121
Gamma-aminobutyric acid receptor subunit gamma-2154121
Gamma-aminobutyric acid receptor subunit alpha-5154121
Gamma-aminobutyric acid receptor subunit alpha-3154121
Gamma-aminobutyric acid receptor subunit gamma-1154121
Gamma-aminobutyric acid receptor subunit alpha-2154121
Gamma-aminobutyric acid receptor subunit alpha-4154121
Gamma-aminobutyric acid receptor subunit gamma-3154121
Gamma-aminobutyric acid receptor subunit alpha-6154121
Aldo-keto reductase family 1 member C30101
Prolyl endopeptidase0101
Aldo-keto reductase family 1 member C2 0101
Gamma-aminobutyric acid receptor subunit alpha-1154121
Gamma-aminobutyric acid receptor subunit beta-3154121
Gamma-aminobutyric acid receptor subunit beta-2154121
Cholinesterase0101
Potassium voltage-gated channel subfamily H member 2012012
GABA theta subunit154121
Gamma-aminobutyric acid receptor subunit epsilon154121
pregnane X receptor9009
galanin receptor type 30101
Glucocorticoid receptor012219
Glycine receptor subunit alpha-1012012
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
ORF730011
Chain A, serum paraoxonase0101
nuclear receptor ROR-gamma isoform 1120012
Carbonic anhydrase 120405
Carbonic anhydrase 30506
Neutrophil cytosol factor 10101
Carbonic anhydrase 60708
Carbonic anhydrase 5A, mitochondrial0608
Carbonic anhydrase 70405
Carbonic anhydrase 90719
Carbonic anhydrase 130303
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140405
Carbonic anhydrase 5B, mitochondrial0406
Beta-lactamase 0002
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 22 member 60404
Beta-lactamase0002
Nuclear receptor subfamily 1 group I member 20044
Solute carrier family 22 member 50101
Beta-lactamase0003
Beta-lactamase0003
Beta-lactamase OXA-100002
Beta-lactamase0002
Beta-lactamase TEM0104
Beta-lactamase0002
Beta-lactamase 0002
Efflux transporter 0003
Beta-lactamase 0003
Beta-lactamase Toho-10003
Beta-lactamase 0003
Solute carrier family 22 member 60404
Beta-lactamase 0002
Solute carrier family 22 member 70203
Beta-lactamase 0002
Metallo-b-lactamase 0003
Beta-lactamase IMP-1 0002
Beta-lactamase 0002
Solute carrier family 22 member 80405
Beta-lactamase 0002
Carbapenem-hydrolyzing beta-lactamase KPC0003
Beta-lactamase class B VIM-2 0003
Beta-lactamase 0002
Solute carrier family 22 member 110203
Solute carrier family 22 member 80304
Solute carrier family 22 member 70203
Chain A, TYROSYL-DNA PHOSPHODIESTERASE130013
Chain A, JmjC domain-containing histone demethylation protein 3A6006
Beta-lactamase 0002
Beta-lactamase 0002
endonuclease IV5005
WRN2002
phosphopantetheinyl transferase110011
GLS protein9009
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase0002
DNA (cytosine-5)-methyltransferase 1 isoform b0101
importin subunit beta-1 isoform 15005
serine/threonine-protein kinase PLK13003
snurportin-15005
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Solute carrier family 22 member 80304
Beta-lactamase OXA-10001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-130002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0002
Histamine H3 receptor0002
Beta-lactamase VIM-1 0002
phosphoglycerate kinase3003
SMAD family member 27007
SMAD family member 37007
estrogen receptor 2 (ER beta)140014
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyrotropin-releasing hormone receptor3003
Caspase-20011
interleukin 8130013
cytochrome P450 2D6100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a100010
streptokinase A precursor0077
lethal factor (plasmid)5005
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60516
30S ribosomal protein S70516
50S ribosomal protein L150516
Cytochrome P450 3A40819
50S ribosomal protein L100516
50S ribosomal protein L110516
50S ribosomal protein L7/L120516
50S ribosomal protein L190516
50S ribosomal protein L10516
50S ribosomal protein L200516
50S ribosomal protein L270516
50S ribosomal protein L280516
50S ribosomal protein L290516
50S ribosomal protein L310516
50S ribosomal protein L31 type B0516
50S ribosomal protein L320516
50S ribosomal protein L330516
50S ribosomal protein L340516
50S ribosomal protein L350516
50S ribosomal protein L360516
30S ribosomal protein S100516
30S ribosomal protein S110516
30S ribosomal protein S120516
30S ribosomal protein S130516
30S ribosomal protein S160516
30S ribosomal protein S180516
30S ribosomal protein S190516
30S ribosomal protein S200516
30S ribosomal protein S20516
30S ribosomal protein S30516
30S ribosomal protein S40516
30S ribosomal protein S50516
30S ribosomal protein S80516
30S ribosomal protein S90516
50S ribosomal protein L130516
50S ribosomal protein L140516
50S ribosomal protein L160516
50S ribosomal protein L230516
30S ribosomal protein S150516
50S ribosomal protein L170516
50S ribosomal protein L210516
50S ribosomal protein L300516
50S ribosomal protein L60516
30S ribosomal protein S140516
30S ribosomal protein S170516
30S ribosomal protein S10516
50S ribosomal protein L180516
50S ribosomal protein L20516
50S ribosomal protein L30516
50S ribosomal protein L240516
50S ribosomal protein L40516
50S ribosomal protein L220516
50S ribosomal protein L50516
30S ribosomal protein S210516
50S ribosomal protein L250516
50S ribosomal protein L36 20516
Methionine--tRNA ligase, mitochondrial0011
Chain A, BCL-2-RELATED PROTEIN A10011
Chain A, Cruzipain7007
acid sphingomyelinase3003
PAX80001
15-lipoxygenase, partial5005
PINK11001
Parkin2002
heat shock protein 900011
calcineurin A1, putative0011
hepatocyte nuclear factor 4-alpha isoform 20202
cytochrome P450 2C19 precursor7007
cytochrome P450 2C9 precursor7007
perilipin-50202
perilipin-10202
huntingtin isoform 26006
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 14004
protein AF-9 isoform a0002
melanocortin receptor 40101
CAAX prenyl protease0002
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0002
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Synaptojanin-10101
Solute carrier family 22 member 30202
Glutathione reductase, mitochondrial0406
72 kDa type IV collagenase0202
Matrix metalloproteinase-90202
Trypanothione reductase0101
Alpha-synuclein4307
Histamine H2 receptor100011
Nuclear receptor ROR-gamma100010
TAR DNA-binding protein 43110011
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Rap guanine nucleotide exchange factor 41001
Spermine oxidase0101
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0134
Replicase polyprotein 1ab0134
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20134
Dihydrofolate reductase 0303
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0303
Histidine-rich protein PFHRP-II0203
Procathepsin L0134
Muscarinic acetylcholine receptor M20718
Muscarinic acetylcholine receptor M40505
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0618
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0134
Spike glycoprotein0101
Replicase polyprotein 1ab0134
Muscarinic acetylcholine receptor M10426
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0102
Alpha-2C adrenergic receptor0304
DNA ligase 10101
Muscarinic acetylcholine receptor M30303
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Sigma non-opioid intracellular receptor 10404
Angiotensin-converting enzyme 2 0134
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120202
Protein-arginine deiminase type-4011011
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 2 0101
Thromboxane A2 receptor 0112
Prostaglandin E2 receptor EP1 subtype0112
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin F2-alpha receptor0213
Prostaglandin E2 receptor EP3 subtype0112
Prostaglandin E2 receptor EP2 subtype0101
Prostacyclin receptor0101
Prostaglandin D2 receptor0101
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
dopamine D1 receptor3003
peripheral myelin protein 22 isoform 13003
atrial natriuretic peptide receptor 1 precursor1001
M-phase phosphoprotein 85005
muscarinic acetylcholine receptor M17007
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Potassium voltage-gated channel subfamily A member 10011
Alkaline phosphatase, germ cell type0101
G protein-coupled receptor GPR350011
G-protein coupled receptor 350011
G-protein coupled receptor 350011
P531001
RPL19A0011
NPC intracellular cholesterol transporter 1 precursor2002
ras-related protein Rab-9A2002
heat shock protein HSP 90-alpha isoform 20103
transactivating tegument protein VP16 [Human herpesvirus 1]0101
COUP transcription factor 2 isoform a0101
Glucose transporter0202
Hexose transporter 1 0202
Polyunsaturated fatty acid 5-lipoxygenase0202
Solute carrier family 2, facilitated glucose transporter member 10202
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0203
Endothelial PAS domain-containing protein 10203
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0002
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
Chain A, N-methyl-D-aspartate Receptor Subunit 10101
Bloom syndrome protein isoform 1100010
D-alanine--D-alanine ligase0101
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 0101
Proton-coupled amino acid transporter 10203
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
RAD510101
Caspase-72002
caspase-32002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
caspase-1 isoform alpha precursor1001
ATP-dependent translocase ABCB10609
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-71001
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0213
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Myeloperoxidase0202
Dihydrofolate reductase0405
5-hydroxytryptamine receptor 60303
arylsulfatase A6006
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Thymidine kinase 2 0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0001
AAA family ATPase 0001
nonstructural protein 14004
DNA polymerase beta6006
Thrombopoietin2002
5-hydroxytryptamine receptor 40404
Aldo-keto reductase family 1 member B10404
Angiotensin-converting enzyme0404
Sodium-dependent noradrenaline transporter 0415
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
Histamine H1 receptor0012
Histamine H1 receptor0202
5-hydroxytryptamine receptor 2B0202
Histamine N-methyltransferase0001
Sodium channel protein type 5 subunit alpha0101
Nuclear receptor subfamily 3 group C member 3 0404
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0101
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
NS5 0011
serine/threonine-protein kinase mTOR isoform 11001
Serine hydrolase RBBP90101
Dihydroorotate dehydrogenase 0101
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
Rap guanine nucleotide exchange factor 34004
Albumin0189
ATP-dependent translocase ABCB10303
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0505
Chitinase B0101
ATP-dependent translocase ABCB10303
Low molecular weight phosphotyrosine protein phosphatase0101
10 kDa heat shock protein, mitochondrial0505
Thiosulfate sulfurtransferase0404
Lanosterol 14-alpha demethylase0404
60 kDa chaperonin 0505
10 kDa chaperonin 0505
Solute carrier organic anion transporter family member 1B30607
Solute carrier organic anion transporter family member 1B10607
exodeoxyribonuclease V subunit RecD0202
exodeoxyribonuclease V subunit RecB0202
exodeoxyribonuclease V subunit RecC0202
Genome polyprotein 0224
chaperonin-containing TCP-1 beta subunit homolog3003
thioredoxin glutathione reductase8008
hypothetical protein, conserved2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
eyes absent homolog 2 isoform a2002
lethal(3)malignant brain tumor-like protein 1 isoform I2002
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0202
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Neuronal acetylcholine receptor subunit alpha-43104
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Neuronal acetylcholine receptor subunit beta-23104
Gamma-aminobutyric acid receptor subunit alpha-10123
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20123
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20112
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Neuronal acetylcholine receptor subunit alpha-70101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
lysosomal alpha-glucosidase preproprotein4004
Androgen receptor0505
Nuclear receptor subfamily 1 group I member 20022
Chain A, Dihydrofolate reductase0011
Thymidylate synthase0303
Thymidylate synthase0102
Dihydrofolate reductase0213
Aldo-keto reductase family 1 member B10202
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0022
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
Estrogen receptor0011
Estrogen receptor beta0011
Canalicular multispecific organic anion transporter 10101
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Glycogen synthase kinase-3 alpha0101
Glycogen synthase kinase-3 beta0101
Protein cereblon0202
Thymidine kinase 0203
Vpr3003
Thymidine kinase, cytosolic0305
Thymidine phosphorylase0002
Thymidine kinase0002
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Large neutral amino acids transporter small subunit 10202
Phospholipase A-2-activating protein0202
Vitamin D3 receptor0112
G-protein coupled bile acid receptor 10011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Cationic amino acid transporter 30101
Glutaminyl-peptide cyclotransferase0101
Chain E, Fibrin beta chain0101
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
isocitrate dehydrogenase 1, partial2002
luciferase1001
serine-protein kinase ATM isoform a3003
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1B adrenergic receptor0303
Amine oxidase [flavin-containing] A0202
Alpha-1D adrenergic receptor0303
Cruzipain0101
Alpha-1A adrenergic receptor0303
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Stromelysin-10314
Matrilysin0101
Multidrug transporter MdfA0202
Protein mono-ADP-ribosyltransferase PARP150202
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Integrin beta-10101
Leukotriene A-4 hydrolase0101
Cytochrome P450 2D60404
Integrin alpha-40101
Cytochrome P450 2C190303
Histone deacetylase 40101
Histone deacetylase 10202
Histone deacetylase 70101
Histone deacetylase 20202
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10315
Muscarinic acetylcholine receptor M30315
Muscarinic acetylcholine receptor M40315
Muscarinic acetylcholine receptor M50315
Muscarinic acetylcholine receptor M20315
Translocator protein0011
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Delta-type opioid receptor0204
Delta-type opioid receptor0315
Kappa-type opioid receptor0215
Mu-type opioid receptor06110
Kappa-type opioid receptor0214
Mu-type opioid receptor0214
UDP-glucuronosyltransferase 1A30001
Delta-type opioid receptor0214
Kappa-type opioid receptor0214
Mu-type opioid receptor0216
Nociceptin receptor0101
5-hydroxytryptamine receptor 70303
Mu-type opioid receptor0101
Mu-type opioid receptor0404
Beta-2 adrenergic receptor0112
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Carbonic anhydrase 0303
Beta-carbonic anhydrase 10303
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
NAD(+) hydrolase SARM10303
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Sodium/iodide cotransporter0101
Metabotropic glutamate receptor 50202
Snake venom metalloproteinase BaP10101
DNA gyrase subunit A0406
DNA gyrase subunit B0416
DNA topoisomerase 4 subunit A0202
Multidrug resistance protein MdtK0011
Chain A, Gyrase0011
DNA gyrase subunit B0101
interferon gamma precursor0001
Heat shock protein HSP 90-alpha0022
Heat shock protein HSP 90-beta0124
DNA gyrase subunit B0203
DNA gyrase subunit B0101
DNA topoisomerase 4 subunit A0101
Cell division inhibitor SulA0001
DNA topoisomerase 4 subunit B0101
DNA gyrase subunit B0101
Heat shock protein HSP 900101
Angiotensin-converting enzyme 0101
DNA topoisomerase 4 subunit B0101
DNA gyrase subunit A0203
DNA gyrase subunit B0304
DNA gyrase subunit A0304
DNA topoisomerase 0101
Microtubule-associated proteins 1A/1B light chain 3B0213
Microtubule-associated proteins 1A/1B light chain 3A0213
STE240001
Trypsin0001
Valosin-containing protein0101
microphthalmia-associated transcription factor isoform 90101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
Serum paraoxonase/arylesterase 10202
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 10001
Class D beta-lactamase0001
Beta-lactamase 0001
BlaVIM-1 0001
Protein arginine N-methyltransferase 50101
Protein tyrosine phosphatase type IVA 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Cytochrome P450 1A20101
Trypsin-10101
Acrosin0101
Amiloride-sensitive amine oxidase [copper-containing]0101
Diamine acetyltransferase 10101
D(3) dopamine receptor0202
Sodium-dependent dopamine transporter 0202
Protein tyrosine phosphatase type IVA 20101
Protein tyrosine phosphatase type IVA 10101
Aurora kinase B0101
Protein arginine N-methyltransferase 10101
Suppressor of tumorigenicity 14 protein0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M10023
Cytochrome P450 2B60112
Muscarinic acetylcholine receptor M40012
Lysosomal Pro-X carboxypeptidase0101
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Endolysin0011
Sulfotransferase 1A1 0001
Cannabinoid receptor 10101
Adenosine receptor A10101
Adenosine receptor A2a0101
Carbonic anhydrase0202
Carbonic anhydrase 0203
Carbonic anhydrase 30202
Carbonic anhydrase0203
Carbonic anhydrase 130304
GALC protein1001
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
Beta-1 adrenergic receptor 0011
Beta-2 adrenergic receptor0011
Renin 0101
Beta-1 adrenergic receptor0011
Beta-2 adrenergic receptor0001
Beta-3 adrenergic receptor0011
Beta-1 adrenergic receptor0012
Beta-2 adrenergic receptor0101
Alpha-1D adrenergic receptor0001
Alpha-1A adrenergic receptor0001
Alpha-1B adrenergic receptor0001
Beta-2 adrenergic receptor0011
Beta-2 adrenergic receptor 0011
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Estrogen receptor beta0202
Solute carrier family 22 member 10101
Solute carrier organic anion transporter family member 1A40202
Solute carrier family 22 member 20101
Potassium channel subfamily K member 20101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Solute carrier organic anion transporter family member 1A10202
Cytochrome P450 2D40101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 172002
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA-directed RNA polymerase subunit beta0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0001
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Carbonic anhydrase 0404
Laccase 0101
Integrase 0202
Carbonic anhydrase 0303
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Fatty acid-binding protein, adipocyte0011
Prostaglandin G/H synthase 20101
Peroxisome proliferator-activated receptor alpha0011
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Dihydrofolate reductase0505
Aurora kinase A0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Endothelin-1 receptor0202
Protease 0112
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase0102
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0102
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 0102
Carbonic anhydrase 40101
Protein argonaute-20011
Cytochrome P450 2C80101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
Cytochrome P450 2C180101
UDP-glucuronosyltransferase 2B10 0101
Endothelin-1 receptor0202
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Urease0203
Urease subunit alpha0101
D(3) dopamine receptor0101
Urease subunit alpha0101
Urease subunit beta0101
Urease subunit beta 0101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Thymidine kinase0102
Thymidine phosphorylase0001
Glucose-6-phosphate 1-dehydrogenase0101
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
Chain A, CARBONIC ANHYDRASE II0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Plasma kallikrein0001
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]