Page last updated: 2024-08-05 14:42:44

herbicide

A substance used to destroy plant pests.

ChEBI ID: 24527

Members (114)

MemberDefinitionClass
1-methyl-4-phenylpyridiniumA pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.N-methyl-4-phenylpyridinium
2-hydroxyethylhydrazine2-hydrazinoethanol
2,4-dihydroxy-1,4-benzoxazin-3-oneA lactol that consists of 1,4-benzoxazine bearing two hydroxy substituents at positions 2 and 4 as well as a keto group at position 3.DIBOA
2,4,6-trichlorophenyl 4-nitrophenyl etherchlornitrofen
2,6-dichlorobenzamideA member of the class of benzamides that is benzamide substituted by chloro groups at positions 2 and 6.2,6-dichlorobenzamide
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acidAn aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2.fluroxypyr
4,6-dinitro-o-cresolA hydroxytoluene that is o-cresol carrying nitro substituents at positions 4 and 6.4,6-dinitro-o-cresol
a 8947An N-sulfonylurea that is urea in which a nitrogen attached to one of the nitrogens has been replaced by a 4,6-dipyrimidin-2-yl group while a hydrogen attached to the other urea nitrogen has been replaced by a [1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazol-5-yl]sulfonyl group. An acetolactate synthase inhibitor, it is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations.azimsulfuron
acetochlorA monocarboxylic acid amide that is N-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively.acetochlor
acifluorfenA member of the class of benzoic acids that is 2-nitrobenzoic acid in which the hydrogen at position 5 is replaced by a 2-chloro-4-(trifluoromethyl)phenoxy group. It is a herbicide used for the post-emergence control of a variety of annual broadleaf weeds.acifluorfen
aclonifenA primary amino compound that is aniline in which the phenyl group has been substituted at positions 2, 3, and 6 by chlorine, phenoxy, and nitro groups, respectively. A protoporphyrinogen oxidase (PPO) inhibitor, it is used as a herbicide against a broad range of weeds in a wide range of crops.aclonifen
acroleinAn enal that is prop-2-ene with an oxo group at position 1.acrolein
alachlorAn aromatic amide that is N-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom.alachlor
allyl alcoholA propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.allyl alcohol
alpha-naphthylphthalamic acidA dicarboxylic acid monoamide which results from addition of one equivalent of 1-naphthylamine to phthalic anhydride.naptalam
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)A beta-diketone and nitrile resulting from the the degradation of the isoxazole ring of isoxaflutole. The active herbicide of the proherbicide isoxaflutole.2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione
ametryneA methylthio-1,3,5-triazine that is 2-(methylsulfanyl)-1,3,5-triazine substituted by an ethylamino and an isopropylamino group at positions 4 and 6 respectively.ametryn
aminocyclopyrachlorAn organochlorine herbicide, the structure of which is that of pyrimidine-4-carboxylic acid substituted at positions 2, 5 and 6 by cyclopropyl, chloro and amino groups respectively.aminocyclopyrachlor
aminopyralidAn organochlorine pesticide having a 3,6-dichlorinated 4-aminopicolinic acid structure.aminopyralid
amitroleA member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.amitrole
asulamA carbamate ester that is methyl carbamate substituted by a (4-aminophenyl)sulfonyl group at the nitrogen atom. A dihydropteroate synthase inhibitor, it is used (normally as the corresponding sodium salt, asulam-sodium) as a herbicide, mainly for killing bracken.asulam
atrazineA diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group.atrazine
barbanA carbamate ester that is 4-chlorobut-2-yn-1-yl ester of N-(3-chlorophenyl)carbamic acid. A herbicide, it is no longer approved for use within the European Community.barban
benefinA tertiany amino compound that is 2,6-dinitro-4-(trifluoromethyl)aniline in which the hydrogens attached to the aniline nitrogen have been replaced by one ethyl and one butyl group. It is used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops.benfluralin
bentazoneA benzothiadiazine that is 1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide substituted by an isopropyl group at position 3.bentazone
bentranilA benzoxazine that is 4H-3,1-benzoxazin-4-one substituted by a phenyl group at position 2. It is a postemergence herbicide used for the control of annual weeds in cereal crops, maize, and rice.bentranil
bispyribacA member of the class of benzoic acids that is benzoic acid substituted by (4,6-dimethoxypyrimidin-2-yl)oxy groups at positions 2 and 6. Its sodium salt is used as a broad spectrum post emergent herbicide for the control of grasses, sedges and broadleaf weeds in rice crops.bispyribac
bpmcA carbamate ester obtained by the formal condensation of 2-sec-butylphenol with methylcarbamic acid.fenobucarb
bromoxynilA dibromobenzene that is 2,6-dibromophenol substituted by a cyano group at position 4.3,5-dibromo-4-hydroxybenzonitrile
butachlorAn aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.butachlor
butafenacilAn organofluorine compound that is 1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione substituted by a 4-chloro-3-({[2-methyl-1-oxo-1-(prop-2-en-1-yloxy)propan-2-yl]oxy}carbonyl)phenyl group at position 3. It is a herbicide which inhibits the protoporphyrinogen-oxidase enzyme in plant chloroplasts, resulting in rapid knockdown of various broadleaf and grass weeds.butafenacil
cafenstrolecafenstrole
cantharidinA monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.cantharidin
chloroacetic acidA chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.chloroacetic acid
chlorprophamA carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid.chlorpropham
chlorsulfuronAn N-sulfonylurea that is N-carbamoyl-2-chlorobenzenesulfonamide in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used for the control of broadleaf weeds in wheat, barley and oats.chlorsulfuron
chlortoluronA member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a 3-chloro-4-methylphenyl group. A herbicide that is non-toxic to honeybees but moderately toxic to mammals, birds, earthworms and most aquatic organisms.chlorotoluron
cinidon-ethylA carboxylic ester and organochlorine compound that is the ethyl ester of cinidon.cinidon ethyl
clodinafop-propargylA carboxylic ester resulting from the formal condensation of the carboxy group of clodinafop with the hydroxy group of prop-2-yn-1-ol. It is widely used as a herbicide for the control of annual grass weeds in cereal crops.clodinafop-propargyl
clofibric acidA monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.clofibric acid
clomazoneAn isoxazolidinone that is 1,2-oxazolidin-3-one substituted by a 2-chlorobenzyl group at position 2 and two methyl groups at position 4.clomazone
clopyralidAn organochlorine pesticide having a 3,6-dichlorinated picolinic acid structure.clopyralid
cloransulam-methylThe methyl ester of cloransulam. An inhibitor of acetohydroxyacid synthase (AHAS), it prevents the synthesis of amino acids in plants and is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. It is not approved for use within the European Area.cloransulam-methyl
cornexistinA cyclic dicarboxylic anhydride that is 5,6,7,8,9,10-hexahydro-1H-cyclonona[c]furan-1,3(4H)-dione substituted by an ethylidene group at position 9, hydroxy groups at position 5 and 8, a propyl group at position 4 and an oxo group at position 6.14-dihydroxycornestin
cyanazineA chloro-1,3,5-triazine that is 2-chloro-1,3,5-triazine substituted by an ethyl amino and a (2-cyanopropan-2-yl)amino group at positions 6 and 4 respectively.cyanazine
dazometA dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the control of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control Salmonella. It is a non-ozone-depleting alternative to methyl bromide.dazomet
desmediphamA carbamate ester that is phenylcarbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(ethoxycarbonyl)amino]phenyl group. It is an agrochemical used as a herbicide.desmedipham
dicambaA methoxybenzoic acid that is O-methylsalicylic acid substituted by chloro groups at positions 3 and 6.dicamba
dichlobanilA nitrile that is benzonitrile which is substituted by chlorines at positions 2 and 6. A cellulose synthesis inhibitor, it is used as a pre-emergent and early post-emergent herbicide.2,6-dichlorobenzonitrile
diflufenicanA pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2.diflufenican
diquatThe organic cation formed formally by addition of an ethylene bridge between the nitrogen atoms of 2,2'-bipyridine. Most often available as the dibromide.diquat
dpx e9636A N-sulfonylurea that is N-carbamoyl-3-(ethylsulfonyl)pyridine-2-sulfonamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen atom.rimsulfuron
ethoxyquinA quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.ethoxyquin
fenuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of weeds in beetroot as well as various vegetable and ornamental crops.fenuron
fluometuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-(trifluoromethyl)phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of broadleaf weeds and annual grasses in cotton.fluometuron
foe 5043An aromatic amide that is acetamide in which the amino hydrogens have been replaced by a propan-2-yl and 4-fluorophenyl groups while the methyl hydrogen is replaced by a [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy group.flufenacet
fomesafenAn N-sulfonylcarboxamide that is N-(methylsulfonyl)benzamide in which the phenyl ring is substituted by a nitro group at position 2 and a 2-chloro-4-(trifluoromethyl)phenoxy group at position 5. A protoporphyrinogen oxidase inhibitor, it was specially developed for use (generally as the corresponding sodium salt, fomesafen-sodium) for post-emergence control of broad-leaf weeds in soya.fomesafen
glyphosateA phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).glyphosate
herbimycinA 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It is an ansamycin antibiotic that induces apoptosis and displays antitumour effects.herbimycin
ioxynilA nitrile that is benzonitrile substituted by a hydroxy group at position 4 and iodo groups at positions 3 and 5.ioxynil
isoproturonA member of the class of phenylureas that is 1,1-dimethylurea substituted by a p-cumenyl group at position 3. A selective, systemic herbicide used to control annual grasses and broadleaf weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.isoproturon
isoxabenA benzamide obtained by formal condensation of the carboxy group of 2,6-dimethoxybenzoic acid and the amino group of 3-(3-methylpentan-3-yl)-1,2-oxazol-5-amine.isoxaben
jugloneA hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.juglone
lenacilA cyclopentapyrimidine that is 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione substituted by a cyclohexyl group at position 3.lenacil
linuronA member of the class of phenylureas that is N-methyl urea substituted by a methoxy group at position 1 and a 3,4-dichlorophenyl group at position 3.linuron
mefenacetmefenacet
mesotrioneAn aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group.mesotrione
metamitronA member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, a methyl group at position 3 and a phenyl group at position 6.metamitron
metazachlorAn organochlorine compound that is 2-chloroacetamide substituted by a 2,6-dimethylphenyl and a (1H-pyrazol-1-ylmethyl) group at the nitrogen atom.metazachlor
methoxuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-chloro-4-methoxyphenyl group while the other is substituted by two methyl groups. It is a plant growth regulator and a pre- and post-emergence herbicide used for the control of grasses and broad-leaved weeds in carrots and cereals (e.g. wheat, barley and rye).metoxuron
methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoateA methyl ester resulting from the formal condensation of the carboxy group of ethametsulfuron with methanol. A herbicide used for the control of broad-leaved weeds in oil seed rape and fodder rape.ethametsulfuron-methyl
methyl bensulfuronThe methyl ester of bensulfuron. An acetolactate synthase inhibitor, it is used as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. It is not licensed for use within the UK.bensulfuron-methyl
metribuzinA member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3.metribuzin
metsulfuron methylA N-sulfonylurea in which the sulfonyl group is attached to a 2-(methoxycarbonyl)phenyl group while a (4-methoxy-6-methyl-1,3,5-triazin-2-yl group replaces one of the amino hydrogens of the remaining urea group.metsulfuron methyl
metsulfuron methylThe methyl ester of tribenuron.tribenuron methyl
molinateA member of the class of azepanes that is azepane in which the nitrogen is substituted by an (ethylsulfanyl)carbonyl group, -C(=O)SEt. A thiocarbamate herbicide not approved for use in the U.S. or European Union, it is used control grass weeds in rice paddies.molinate
monuronA member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a p-chlorophenyl group while the other is substituted by two methyl groups.monuron
n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamideA member of the class of triazoles that is 5-oxo-1,2,4-triazole which is substituted at positions 1, 3, and 4 by 2,4-dichloro-5-[(methylsulfonyl)amino]phenyl, methyl, and difluoromethyl groups, respectively. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. Not approved for use within the European Union.sulfentrazone
nicosulfuronA N-sulfonylurea that is 2-(carbamoylsulfamoyl)-N,N-dimethylpyridine-3-carboxamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen.nicosulfuron
nitrofennitrofen
norflurazoneA pyridazinone that is pyridazin-3(2H)-one which is substituted at positions 2, 4, and 5 by m-(trifluoromethyl)phenyl, chloro, and methylamino groups, respectively. A pre-emergence herbicide used to control grasses and broad-leafed weeds in a variety of crops. Not approved for use within the European Union.norflurazon
oryzalinA sulfonamide that is benzenesulfonamide substituted at positions 3 and 5 by nitro groups and at position 4 by a dipropylamino group.oryzalin
oxyfluorofenOxyfluorfen
paraquatAn organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.paraquat
pendimethalinA member of the class of substituted anilines that is N-(pentan-3-yl)aniline bearing two additional nitro substituents at positions 2 and 6 as well as two methyl substituents at positions 3 and 4. A herbicide used to control most annual grasses and many annual broad-leaved weeds.pendimethalin
phenmediphamA carbamate ester that is (3-methylphenyl)carbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(methoxycarbonyl)amino]phenyl group.phenmedipham
picloramA pyridinemonocarboxylic acid that is pyridine-2-carboxylic acid which is substituted by a chloro group at positions 3,5 and 6, and by an amino group at position 4. It is a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops.picloram
picloram-methylA methyl ester resulting from the formal condensation of the carboxy group of picloram with methanol.picloram-methyl
potassium cyanatepotassium cyanate
prometoneA methoxy-1,3,5-triazine that is 6-methoxy-1,3,5-triazine-2,4-diamine in which the one of the hydrogens of each amino group is substituted by an isopropyl group.prometon
prometryneA diamino-1,3,5-triazine that is N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a methylsulfanediyl group at position 6.prometryn
pronamideA member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops.propyzamide
propachlorAn anilide that consists of 2-chloroacetanilide bearing an N-isopropyl substituent.propachlor
propanilAn anilide resulting from the formal condensation of the carboxy group of propanoic acid with the amino group of 3,4-dichloroaniline. It is a herbicide used for the treatment of numerous grasses and broad-leaved weeds in rice, potatoes, and wheat.propanil
propazineA diamino-1,3,5-triazine that is N,N'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.propazine
prophamA carbamate ester that is the isopropyl ester of phenylcarbamic acid. It is a selective herbicide used for the control of annual grasses and some broad-leaf weeds and is also a growth regulator for control of sprouting in stored potatoes.propham
prosulfocarbA monothiocarbamic ester that is carbamothioic S-acid substituted by two propyl groups at the nitrogen atom and a benzyl group at the the sulfur atom.prosulfocarb
pyrazonA pyridazinone that is pyridazin-3(2H)-one substituted by an amino group at position 5, a chloro group at position 4 and a phenyl group at position 2.chloridazon
quincloracA quinolinemonocarboxylic acid that is quinoline-8-carboxylic acid in which the hydrogens at positions 3 and 7 have been replaced by chlorines. It is used (particularly as its dimethylamine salt, known as quinclorac-dimethylammonium) as a (rather persistent) herbicide for the post-emergence control of weeds in rice, grass and turf. It is not approved for use within the European Union.quinclorac
raiserflurochloridone
s 53482A benzoxazine that is N-(prop-2-yn-1-yl)-2H-1,4-benzoxazin-3(4H)-one which is substituted at position 6 by a 1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl group and at position 7 by a fluorine. A protoporphyrinogen oxidase inhibitor, it is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops.flumioxazin
simazineA diamino-1,3,5-triazine that is N,N'-diethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.simazine
simetrynA diamino-1,3,5-triazine that is N,N'-diethyl-1,3,5-triazine-2,4-diamine substituted by a methylthio group at position 6.simetryn
sodium arseniteAn inoganic sodium salt with formula with formula NaAsO2.sodium arsenite
sodium chlorateAn inorganic sodium salt that has chlorate as the counter-ion. An oxidising agent, it is used for bleaching paper and as a herbicide. It is also used in the manufacture of dyes, explosives and matches.sodium chlorate
sulcotrioneAn aromatic ketone that is cyclohexane-1,3-dione substituted by a 2-chloro-4-(methylsulfonyl)benzoyl group at position 2.sulcotrione
sulfometuron methylA benzoate ester that is the methyl ester of 2-{[(4,6-dimethylpyrimidin-2-yl)carbamoyl]sulfamoyl}benzoic acid.sulfometuron methyl
tembotrioneAn aromatic ketone that is 2-benzoylcyclohexane-1,3-dione in which the phenyl group is substituted at positions 2, 3, and 4 by chlorine, (2,2,2-trifluoroethoxy)methyl, and methylsulfonyl groups, respectively. It is a post-emergence herbicide used (particularly in conjunction with the herbicide safener cyprosulfamide) for the control of a wide range of broad-leaved and grassy weeds in corn and other crops.tembotrione
terbutryneA methylthio-1,3,5-triazine that is 2-(methylsulfanyl)-1,3,5-triazine substituted by a tert-butylamino and an ethylamino group at positions 2 and 4 respectively.terbutryn
terbutylazineA diamino-1,3,5-triazine that is N-tert-butyl-N'-methyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.terbutylazine
thifensulfuron methylA methyl ester resulting from the formal condensation of the carboxy group of thifensulfuron with methanol. It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds.thifensulfuron-methyl
triasulfuronAn N-sulfonylurea that is N-[o-(2-chloroethoxy)phenyl]sulfonylurea in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used to control broad-leaved weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life.triasulfuron
triclopyrA monocarboxylic acid that is (pyridin-2-yloxy)acetic acid substituted by chloro groups at positions 3, 5 and 6. It is an agrochemical used as a herbicide.trichlopyr
trifluralinA substituted aniline that is N,N-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide.trifluralin

Research

Studies (67,674)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199025,183 (37.21)18.7374
1990's9,687 (14.31)18.2507
2000's12,819 (18.94)29.6817
2010's14,610 (21.59)24.3611
2020's5,375 (7.94)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1,443 (1.90%)5.53%
Reviews3,858 (5.08%)6.00%
Case Studies1,747 (2.30%)4.05%
Observational88 (0.12%)0.25%
Other68,743 (90.60%)84.16%

Protein Targets (232)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency15.587315
15-lipoxygenase, partialHomo sapiens (human)Potency17.831614
67.9K proteinVaccinia virusPotency22.387212
acetylcholinesteraseHomo sapiens (human)Potency53.0030435
acid sphingomyelinaseHomo sapiens (human)Potency25.118911
activating transcription factor 6Homo sapiens (human)Potency30.0897218
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency20.3914213
Alpha-synucleinHomo sapiens (human)Potency2.818411
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency19.317613
AR proteinHomo sapiens (human)Potency30.234812296
aryl hydrocarbon receptorHomo sapiens (human)Potency35.2938377
ATAD5 protein, partialHomo sapiens (human)Potency21.843922
Ataxin-2Homo sapiens (human)Potency27.3144115
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency31.8915221
Bloom syndrome protein isoform 1Homo sapiens (human)Potency12.323213
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency50.118711
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency34.929314
caspase-1 isoform alpha precursorHomo sapiens (human)Potency19.952611
caspase-3Cricetulus griseus (Chinese hamster)Potency48.226215
caspase-3Homo sapiens (human)Potency34.929314
Caspase-7Cricetulus griseus (Chinese hamster)Potency48.226215
Caspase-7Homo sapiens (human)Potency1.000011
Cellular tumor antigen p53Homo sapiens (human)Potency38.0325346
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency14.880628
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency23.249918
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency16.436625
Chain A, Beta-lactamaseEscherichia coli K-12Potency1.724712
Chain A, Breast cancer type 1 susceptibility proteinHomo sapiens (human)Potency3.162311
Chain A, CruzipainTrypanosoma cruziPotency7.943311
Chain A, Ferritin light chainEquus caballus (horse)Potency25.338913
Chain A, HADH2 proteinHomo sapiens (human)Potency17.490127
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency44.668411
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency9.115529
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency8.488314
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency34.9715214
Chain B, HADH2 proteinHomo sapiens (human)Potency17.490127
chromobox protein homolog 1Homo sapiens (human)Potency82.913414
ClpPBacillus subtilisPotency33.552012
core-binding factor subunit beta isoform 2Homo sapiens (human)Potency17.324333
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.422212
cytochrome P450 2C9 precursorHomo sapiens (human)Potency1.995311
cytochrome P450 2C9, partialHomo sapiens (human)Potency12.083214
cytochrome P450 2D6Homo sapiens (human)Potency25.184611
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency3.761912
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency19.7731220
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency24.905212
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency31.6550133
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency12.589311
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency89.125117
DNA polymerase kappa isoform 1Homo sapiens (human)Potency22.120719
estrogen nuclear receptor alphaHomo sapiens (human)Potency32.786412310
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency39.5551347
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency30.56799252
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency24.361612
farnesoid X nuclear receptorHomo sapiens (human)Potency32.5241433
flap endonuclease 1Homo sapiens (human)Potency35.481311
Fumarate hydrataseHomo sapiens (human)Potency35.716812
GVesicular stomatitis virusPotency12.083214
GABA theta subunitRattus norvegicus (Norway rat)Potency19.7731110
GALC proteinHomo sapiens (human)Potency50.118711
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency19.7731110
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency19.7731110
gemininHomo sapiens (human)Potency8.8720210
GLI family zinc finger 3Homo sapiens (human)Potency18.31213109
glp-1 receptor, partialHomo sapiens (human)Potency11.407328
GLS proteinHomo sapiens (human)Potency37.630712
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency29.1738552
Glutamate receptor 1Rattus norvegicus (Norway rat)Potency10.000011
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency36.1547233
Glutamate receptor 3Rattus norvegicus (Norway rat)Potency10.000011
Glutamate receptor 4Rattus norvegicus (Norway rat)Potency10.000011
Guanine nucleotide-binding protein GHomo sapiens (human)Potency28.569024
heat shock protein beta-1Homo sapiens (human)Potency37.8053229
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency6.387729
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency10.642415
histone deacetylase 9 isoform 3Homo sapiens (human)Potency27.0412229
Histone H2A.xCricetulus griseus (Chinese hamster)Potency72.1642220
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency12.083214
hypothetical protein, conservedTrypanosoma bruceiPotency31.622811
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency35.8601216
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency1.885424
IDH1Homo sapiens (human)Potency3.662611
importin subunit beta-1 isoform 1Homo sapiens (human)Potency100.000011
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency12.083218
Integrin alpha-IIbHomo sapiens (human)Potency8.149814
Integrin beta-3Homo sapiens (human)Potency8.149814
Interferon betaHomo sapiens (human)Potency14.250238
interleukin 8Homo sapiens (human)Potency70.901112
lamin isoform A-delta10Homo sapiens (human)Potency8.252015
lethal factor (plasmid)Bacillus anthracis str. A2012Potency15.065412
LuciferasePhotinus pyralis (common eastern firefly)Potency50.5858120
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency39.810722
Microtubule-associated protein tauHomo sapiens (human)Potency23.783224
mitogen-activated protein kinase 1Homo sapiens (human)Potency14.062027
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency39.810711
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Potency39.810711
neuropeptide S receptor isoform AHomo sapiens (human)Potency10.000011
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency7.692212
Nrf2Homo sapiens (human)Potency24.583914
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency37.92444134
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency20.597913
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency15.848911
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency23.6713111
Nuclear receptor ROR-gammaHomo sapiens (human)Potency20.646515
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency13.1825214
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency30.70753168
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency1.995322
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency33.8253568
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)Potency30.362213
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency26.7437568
phosphopantetheinyl transferaseBacillus subtilisPotency33.372414
plasminogen precursorMus musculus (house mouse)Potency6.309611
Platelet-activating factor receptorHomo sapiens (human)Potency3.162311
polyproteinZika virusPotency35.716812
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency12.589311
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency8.583913
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency14.125411
PPM1D proteinHomo sapiens (human)Potency5.868212
pregnane X nuclear receptorHomo sapiens (human)Potency34.30112116
pregnane X receptorRattus norvegicus (Norway rat)Potency44.1358120
progesterone receptorHomo sapiens (human)Potency35.5466246
RAR-related orphan receptor gammaMus musculus (house mouse)Potency28.9952289
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency35.45993120
retinoid X nuclear receptor alphaHomo sapiens (human)Potency25.28214101
runt-related transcription factor 1 isoform AML1bHomo sapiens (human)Potency17.324333
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency26.679511
SMAD family member 2Homo sapiens (human)Potency38.3235325
SMAD family member 3Homo sapiens (human)Potency38.3235325
Smad3Homo sapiens (human)Potency5.091012
snurportin-1Homo sapiens (human)Potency100.000011
survival motor neuron protein isoform dHomo sapiens (human)Potency10.000012
TAR DNA-binding protein 43Homo sapiens (human)Potency12.431914
TDP1 proteinHomo sapiens (human)Potency24.7271228
thioredoxin glutathione reductaseSchistosoma mansoniPotency66.896812
thioredoxin reductaseRattus norvegicus (Norway rat)Potency63.790125
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency52.0254383
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency13.5533424
thyroid stimulating hormone receptorHomo sapiens (human)Potency31.9483653
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency24.988925
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency12.589311
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency6.309611
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency6.309611
USP1 protein, partialHomo sapiens (human)Potency26.392526
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency34.8291231
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency25.3007553
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency37.520218
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency36.9721132
VprHuman immunodeficiency virus 1Potency0.794311

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-cis-phytoene desaturaseSynechococcus elongatus PCC 7942 = FACHB-805IC500.285013
2-dehydro-3-deoxyphosphooctonate aldolaseNeisseria meningitidis MC58Ki260.000011
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZYersinia pseudotuberculosis YPIIIIC505.350012
3-ketoacyl-CoA synthase 18Arabidopsis thaliana (thale cress)IC500.149812
3-ketoacyl-CoA synthase 20Arabidopsis thaliana (thale cress)IC500.398111
4-hydroxyphenylpyruvate dioxygenaseArabidopsis thaliana (thale cress)IC500.250011
4-hydroxyphenylpyruvate dioxygenaseArabidopsis thaliana (thale cress)Ki0.013022
5-lipoxygenase Bos taurus (cattle)IC5017.000011
Acetolactate synthase Raphanus raphanistrumIC5033.338033
Acetolactate synthase catalytic subunit, mitochondrialSaccharomyces cerevisiae S288CKi0.185615
Acetolactate synthase, chloroplasticArabidopsis thaliana (thale cress)Ki0.253011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC503.035012
Aurora kinase AHomo sapiens (human)IC500.050011
Aurora kinase BHomo sapiens (human)IC500.620011
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydrataseHelicobacter pyloriKi6.800011
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferaseAgrobacterium sp. CP4IC505,580.000014
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydrataseHelicobacter pyloriKi6.800011
Chymotrypsinogen ABos taurus (cattle)IC5011.700011
Chymotrypsinogen ABos taurus (cattle)Ki8.700011
Cytochrome P450 71B1Thlaspi arvenseIC5012.000011
DNA topoisomerase 1Homo sapiens (human)IC508.260011
Dual specificity protein phosphatase 1Mus musculus (house mouse)IC5013.000011
Dual specificity protein phosphatase 6Rattus norvegicus (Norway rat)IC5012.400011
Fatty acid-binding protein, intestinalHomo sapiens (human)Ki17.700011
Fatty-acid amide hydrolase 1Homo sapiens (human)IC500.264522
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)IC500.077011
Glutamine synthetase Nicotiana tabacum (common tobacco)IC50100.000011
Glutamine synthetase Spinacia oleracea (spinach)IC50100.000011
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)IC501.000022
Integrase Human immunodeficiency virus 1IC500.170011
M-phase inducer phosphatase 2Homo sapiens (human)IC501.980011
Neutrophil elastaseHomo sapiens (human)IC5017.000011
Neutrophil elastaseHomo sapiens (human)Ki9.549922
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)IC509.534055
Photosystem II protein D1Spinacia oleracea (spinach)IC500.080011
Protein phosphatase 1BHomo sapiens (human)IC501.780011
Protoporphyrinogen oxidaseHomo sapiens (human)Ki0.968634
Protoporphyrinogen oxidase Zea maysIC500.003211
Protoporphyrinogen oxidase, chloroplasticNicotiana tabacum (common tobacco)Ki0.030011
Protoporphyrinogen oxidase, mitochondrialNicotiana tabacum (common tobacco)Ki0.070011
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B Gallus gallus (chicken)IC500.630044
Serine/threonine-protein phosphatase PP1-gamma catalytic subunitHomo sapiens (human)IC501.780011
Sodium-dependent serotonin transporterHomo sapiens (human)Ki48.000011
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)Ki6.900022
Solute carrier family 22 member 1 Homo sapiens (human)Ki12.300011
Solute carrier family 22 member 2Homo sapiens (human)Ki2.400011
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)Ki1.800011
Solute carrier family 22 member 3Homo sapiens (human)Ki54.000011
Tubulin alpha-1A chainSus scrofa (pig)IC5040.000012
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC503.600011
Zeta-carotene desaturase, chloroplastic/chromoplasticCapsicum annuumIC50100.000012

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
4-hydroxyphenylpyruvate dioxygenaseDaucus carota (carrot)Kd0.006011
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)EC50300.000011
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)EC50300.000011
Hsf1 proteinMus musculus (house mouse)EC50195.000011
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)EC500.042011
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)EC5052.177899
Peroxisome proliferator-activated receptor alphaMus musculus (house mouse)EC5033.680733
Peroxisome proliferator-activated receptor deltaHomo sapiens (human)EC5055.000011
Peroxisome proliferator-activated receptor gammaHomo sapiens (human)EC50221.333333
Peroxisome proliferator-activated receptor gammaMus musculus (house mouse)EC50450.000022
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)EC5011.069256

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7Homo sapiens (human)AC5050.000011
Cytochrome P450 71B1Thlaspi arvenseKs60.000011
DNA topoisomerase 1Homo sapiens (human)MIC5.000011
Photosystem I iron-sulfur center Panicum virgatum (switchgrass)Activity110.000011
POU domain, class 2, transcription factor 2Homo sapiens (human)Km2.700011
Solute carrier family 22 member 1Mus musculus (house mouse)Km10.000011
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)Km8.675044
Solute carrier family 22 member 1 Homo sapiens (human)Activity23.850022
Solute carrier family 22 member 1 Homo sapiens (human)Km14.600011
Solute carrier family 22 member 2Homo sapiens (human)Activity7.800011
Solute carrier family 22 member 2Homo sapiens (human)Km14.880045
Solute carrier family 22 member 2Mus musculus (house mouse)Km24.000011
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)Km14.466733
Solute carrier family 22 member 3Homo sapiens (human)Km47.000011
Solute carrier family 22 member 3Rattus norvegicus (Norway rat)Km57.500022