Page last updated: 2024-08-05 15:14:27

insect sterilant

A chemosterilant intended to sterilize insects.

ChEBI ID: 67105

Members (4)

MemberDefinitionClass
busulfanA methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.busulfan
diflubenzuronA benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group.diflubenzuron
hempahexamethylphosphoric triamide
triethylenemelaminetretamine

Research

Studies (5,749)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19902,383 (41.45)18.7374
1990's770 (13.39)18.2507
2000's919 (15.99)29.6817
2010's1,187 (20.65)24.3611
2020's490 (8.52)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials651 (10.70%)5.53%
Reviews329 (5.41%)6.00%
Case Studies499 (8.20%)4.05%
Observational18 (0.30%)0.25%
Other4,585 (75.39%)84.16%

Protein Targets (41)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-lipoxygenase, partialHomo sapiens (human)Potency31.622811
activating transcription factor 6Homo sapiens (human)Potency41.655513
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.810711
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency39.810711
AR proteinHomo sapiens (human)Potency15.627324
aryl hydrocarbon receptorHomo sapiens (human)Potency10.973037
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency25.118911
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency89.125111
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency5.495011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency0.515712
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency15.848911
estrogen nuclear receptor alphaHomo sapiens (human)Potency16.0926713
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency20.424036
EWS/FLI fusion proteinHomo sapiens (human)Potency8.316422
farnesoid X nuclear receptorHomo sapiens (human)Potency0.389011
gemininHomo sapiens (human)Potency0.562311
GLI family zinc finger 3Homo sapiens (human)Potency0.344511
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency3.548111
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency39.445912
lamin isoform A-delta10Homo sapiens (human)Potency0.794311
lethal factor (plasmid)Bacillus anthracis str. A2012Potency25.118911
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency45.553423
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency0.000611
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency1.322935
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency14.125411
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency31.016822
pregnane X nuclear receptorHomo sapiens (human)Potency26.278622
RAR-related orphan receptor gammaMus musculus (house mouse)Potency5.987825
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency6.047637
retinoid X nuclear receptor alphaHomo sapiens (human)Potency19.458934
TDP1 proteinHomo sapiens (human)Potency24.844522
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency21.756111
thyroid stimulating hormone receptorHomo sapiens (human)Potency39.810711
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency15.848911
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency2.454411
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency39.445912

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
Bile salt export pumpHomo sapiens (human)IC50422.666733
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50133.000011
Matrix metalloproteinase-9Homo sapiens (human)IC505.215011
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011