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reactive nitrogen species

A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively.

ChEBI ID: 62764

Members (2)

MemberDefinitionRole
nitratesA nitrogen oxoanion formed by loss of a proton from nitric acid. Principal species present at pH 7.3.nitrate
nitritesThe nitrogen oxoanion formed by loss of a proton from nitrous acid.nitrite

Research

Studies (41,904)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19909,021 (21.53)18.7374
1990's5,370 (12.82)18.2507
2000's11,323 (27.02)29.6817
2010's11,754 (28.05)24.3611
2020's4,436 (10.59)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,523 (2.95%)5.53%
Reviews2,711 (5.26%)6.00%
Case Studies433 (0.84%)4.05%
Observational60 (0.12%)0.25%
Other46,824 (90.83%)84.16%