tetracycline and Leg-Dermatoses

Cold panniculitis is a form of physical panniculitis due to exposure of skin to severe cold. It usually appears on the cheeks of infants and children. It has also been reported on the thighs and buttocks of young females. Its clinical manifestations include red, cold, indurated plaques or nodules which appear one to three days after exposure to low temperatures and resolve spontaneously within several weeks without scarring. The histopathological picture shows a perivascular infiltrate of lymphoid and histiocytic cells at the dermal-subcutaneous junction in the early phase of the reaction (1). After 48 to 72 hours, a well developed panniculitis appears. We report an unusual case of an adult female patient with recurrent panniculitis on her legs appearing in the winter but without any preceding repeated or prolonged exposure to cold. She responded dramatically to oral tetracycline. This drug was successful as a prophylactic agent as well.

Topics: Administration, Oral; Anti-Bacterial Agents; Cold Temperature; Dermis; Environmental Exposure; Female; Histiocytes; Humans; Leg Dermatoses; Lymphocytes; Middle Aged; Panniculitis; Recurrence; Seasons; Tetracycline

The atypical or environmental mycobacterial organisms constitute a large group of potential agents in the pathogenesis of cutaneous infection. The most commonly encountered mycobacterial infection after contact with water is Mycobacterium marinum. We report an unusual case of cutaneous mycobacterial infection caused by a newly described opportunistic mycobacteria, M. avium-intracellulare scrofulaceum intermediate. This case emphasizes the difficulty in distinguishing among the species M. avium-intracellulare, M. scrofulaceum, and M. gordonae.

Topics: Adult; Humans; Leg Dermatoses; Male; Mycobacterium avium-intracellulare Infection; Recreation; Tetracycline; Water Microbiology

Topics: Bandages; Humans; Hydrocortisone; Iatrogenic Disease; Leg Dermatoses; Leg Ulcer; Neomycin; Tetracycline