A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups.
| Member | Definition | Role |
|---|
| 1-(1-phenylcyclohexyl)pyrrolidine | Pyrrolidine in which the hydrogen attached to the nitrogen is substituted by a 1-phenylcyclohex-1-yl group. | rolicyclidine |
| 2-(4-(dimethylamino)styryl)-1-methylpyridinium | | 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide |
| 3-quinuclidinol | Quinuclidine in which a hydrogen atom at position 3 is substituted by a hydroxy group. | 3-quinuclidinol |
| 4-(4-dihexadecylaminostyryl)-n-methylpyridium | A pyridinium cation with a methyl substituent at the 1-position and a 4-(dihexadecylamino)styryl substituent at the 4-position. | 4-(4-dihexadecylaminostyryl)-N-methylpyridium |
| almotriptan | An indole compound having a 2-(dimethylamino)ethyl group at the 3-position and a (pyrrolidin-1-ylsulfonyl)methyl group at the 5-position. | almotriptan |
| alverine | A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome. | alverine |
| amitriptyline | An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5. | amitriptyline |
| ay 25545 | A C-glycosylated naphthoisochromene derivative obtained from Streptomyces ravidus; exhibits antibiotic and anticancer properties. | ravidomycin |
| azatadine | A benzo[5,6]cyclohepta[1,2-b]pyridine having a 1-methylpiperidin-4-ylidene group at the 11-position. | azatadine |
| benzphetamine | Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity. | benzphetamine |
| bepridil | A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl. | bepridil |
| bufotenin | A tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5. | bufotenin |
| butenafine | Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections. | butenafine |
| butylate | | Butylate |
| ceratamine a | An organic heterobicyclic compound, which is imidazo[4,5-d]azepin-5(6H)-one substituted by a 3,5-dibromo-4-methoxybenzyl group at position 4, a methyl group at position 6 and a methylamino group at position 2. It is an antimitotic alkaloid isolated from the marine sponge Pseudoceratina. | ceratamine A |
| chlorpromazine | A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety. | chlorpromazine |
| clomiphene | | clomiphene |
| cyproheptadine | The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia. | cyproheptadine |
| deanol | A tertiary amine that is ethanolamine having two N-methyl substituents. | N,N-dimethylethanolamine |
| di-allate | | Diallat |
| dicyclomine | The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome. | dicyclomine |
| diethylpropion | An aromatic ketone that is propiophenone in which one of the hydrogens alpha- to the carbonyl is substituted by a diethylamino group. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as the hydrochloride as an anoretic in the short term management of obesity. | diethylpropion |
| difenoxin | A piperidinemonocarboxylic acid that is 4-phenylpiperidine-4-carboxylic acid in which the hydrogen attached to the nitrogen atom is substituted by a 3-cyano-3,3-diphenylpropyl group. | difenoxin |
| diphenoxylate | A piperidinecarboxylate ester that is the ethyl ester of difenoxin. | diphenoxylate |
| diphenylpyraline | A member of the class of piperidines that is the benzhydryl ether derivative of 1-methyl-4-hydroxypiperidine. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders. It is also used as the teoclate salt (piprinhydrinate) as an ingredient in compound preparations for the symptomatic relief of coughs and the common cold. | diphenylpyraline |
| disperse blue 124 | A monoazo compound consisting of diazene with a 5-nitrothiazol-2-yl group attached to one nitrogen and a substituted 4-aminophenyl group attached to the other; used as a dye standard for the assay of allergy-releasing dyes in textiles. | Disperse Blue 124 |
| doxylamine | | doxylamine |
| eptc | | EPTC |
| fenpropidine | A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group. | 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine |
| fexofenadine | A piperidine-based anti-histamine compound. | fexofenadine |
| fm1 43 | | FM 1-43 dye |
| lobeline | An optically active piperidine alkaloid having a 2-oxo-2-phenylethyl substituent at the 2-position and a 2-hydroxy-2-phenylethyl group at the 6-position. | (-)-lobeline |
| lumefantrine | A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria. | lumefantrine |
| lupanine | The delta-lactam obtained by formal oxidation at the 2-position of sparteine. The major alkaloid from the seeds of Lupinus exaltatus, L. mexicanus and L. rotundiflorus, it is among the most important of the tetracyclic quinolizidine alkaloids. | lupanine |
| methotrimeprazine | A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. | methotrimeprazine |
| n,n-dimethylaniline | A tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups. | N,N-dimethylaniline |
| n,n-dimethylcyclohexylamine | A tertiary amine consisting of cyclohexane having a dimethylamino substituent. | N,N-dimethylcyclohexylamine |
| n(6),n(6)-dimethyladenine | A tertiary amine that is adenine substituted at N-6 by geminal methyl groups. | N(6),N(6)-dimethyladenine |
| naftifine | A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections. | naftifine |
| otonecine | | Otonecine |
| pebulate | | Pebulate |
| picogreen | A cyanine dye that is 1-phenylquinoline which is substituted at position 2 by a bis[3-(dimethylamino)propyl]amino group and at position 4 by a (3-methyl-1,3-benzothiazol-3-ium-2-yl)methylene group. The counter ion is not stated. A fluorochrome that selectively binds double-stranded DNA and has characteristics similar to that of SYBR-Green I. | PicoGreen |
| promazine | A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position. | promazine |
| promethazine | A tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety. | promethazine |
| ropinirole | | ropinirole |
| s,n,n'-tripropylthiocarbamate | | S-propyl dipropylcarbamothioate |
| sybr green i | A benzothiazolium ion resulting from the methylation of the nitrogen of the benzothiazole group of N-[4-(1,3-benzothiazol-2-ylmethylene)-1-phenyl-1,4-dihydroquinolin-2-yl]-N',N'-dimethyl-N-propylpropane-1,3-diamine. A cationic unsymmetrical cyanine dye that binds to double-stranded DNA and is used as a nucleic acid stain in molecular biology. | SYBR Green I |
| terbinafine | A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. | terbinafine |
| tolterodine | | tolterodine |
| toremifene | | toremifene |
| triallate | | Tri-allate |
| tributylamine | | tributylamine |
| triethylamine | A tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group. | triethylamine |
| triflupromazine | A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position. | triflupromazine |
| trimethylamine | A tertiary amine that is ammonia in which each hydrogen atom is substituted by an methyl group. | trimethylamine |
| tripropylamine | A tertiary amine that is ammonia in which each hydrogen atom is substituted by a propyl group. | tripropylamine |