A dithioacetal of formula R2C(SR')2, R =/= H, R' =/= H.
ChEBI ID: 59800
| Member | Definition | Role |
|---|---|---|
| probucol | A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. | probucol |
| spirapril | spirapril | |
| spiraprilat | An azaspiro compound that is spirapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid group. It is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor spirapril. | spiraprilat |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 284 (18.49) | 18.7374 |
| 1990's | 551 (35.87) | 18.2507 |
| 2000's | 355 (23.11) | 29.6817 |
| 2010's | 282 (18.36) | 24.3611 |
| 2020's | 64 (4.17) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 240 (14.71%) | 5.53% |
| Reviews | 161 (9.87%) | 6.00% |
| Case Studies | 44 (2.70%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,186 (72.72%) | 84.16% |