A compound consisting of a peptide with attached lipid.
ChEBI ID: 46895
| Member | Definition | Role |
|---|---|---|
| ciliatamide a | A lipopeptide that contains N-methylphenylalanine and lysine as the amino acid residues linked to a dec-9-enoyl moiety via an amide linkage (the R,R stereoisomer). It is isolated from the deep sea sponge Aaptos ciliata and exhibits antileishmanial activity. | ciliatamide A |
| liraglutide | A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | liraglutide |
| ly-146032 | A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue. | daptomycin |
| semaglutide | A polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes. | semaglutide |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 181 (6.16) | 29.6817 |
| 2010's | 1,636 (55.70) | 24.3611 |
| 2020's | 1,120 (38.13) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 583 (18.78%) | 5.53% |
| Reviews | 627 (20.19%) | 6.00% |
| Case Studies | 96 (3.09%) | 4.05% |
| Observational | 63 (2.03%) | 0.25% |
| Other | 1,736 (55.91%) | 84.16% |