The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized.
| Member | Definition | Class |
|---|
| 11-cis-retinal | A retinal having 2E,4Z,6E,8E-double bond geometry. | 11-cis-retinal |
| 6-hydroxy-2,4,5-triaminopyrimidine | A member of the class of aminopyrimidines that is 2,5,6-triaminopyrimidine carrying an additional hydroxy substituent at position 4. | 2,5,6-triamino-4-hydroxypyrimidine |
| alizarin | A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2. | alizarin |
| proflavine | An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds. | 3,6-diaminoacridine |
| thiourea | The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur. | thiourea |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 31.8326 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 7.5060 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 25.2464 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 9.5205 | 1 | 1 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 25.9366 | 2 | 4 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 11.8832 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 21.1546 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 29.9150 | 2 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 17.3768 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 34.6713 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 35.7168 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 20.8329 | 2 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 65.9602 | 2 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 84.3679 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 14.0027 | 1 | 3 |
| endonuclease IV | Escherichia coli | Potency | 12.5893 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.6318 | 4 | 4 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 7.4978 | 2 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 13.3937 | 2 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 7.7560 | 2 | 2 |
| G | Vesicular stomatitis virus | Potency | 17.3768 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 7.7741 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 60.2243 | 2 | 2 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 15.8489 | 1 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 29.9033 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 29.8493 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 35.3515 | 2 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 17.3768 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 141.2540 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 17.3768 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 2 | 3 |
| Interferon beta | Homo sapiens (human) | Potency | 17.3768 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 44.6684 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 30.1230 | 2 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 8.9125 | 1 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.1572 | 2 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 4.2160 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 15.8489 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 11.2117 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 7.4972 | 1 | 1 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 22.8469 | 2 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 33.4915 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 26.8325 | 1 | 1 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 2.2387 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 141.2540 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 16.0342 | 4 | 4 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 41.3638 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 49.5652 | 2 | 3 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Vpr | Human immunodeficiency virus 1 | Potency | 12.5893 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |