Chancroid

Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.

Synonym
Chancroid

Excerpt	Reference
"Although chancroid is an uncommon venereal disease in Australia, its incidence is still high in many tropical countries."	( Bishop, L; Harvey, K; Jones, T; Silver, D, 1977)
"Chancroid is linked to the spread of human immunodeficiency virus type 1 (HIV-1) in East Africa."	( Agoki, E; D'Costa, LJ; Ndinya-Achola, JO; Ombette, J; Plourde, PJ; Plummer, FA; Ronald, AR; Slaney, LA, 1992)
"Chancroid is more difficult to treat in HIV infected men with one-third of patients failing single dose treatment regimens as compared to less than five percent of men without HIV infection."	( Cameron, DW; D'Costa, LJ; Jessamine, PG; Ndinya Achola, JO; Plourde, P; Plummer, FA; Ronald, AR; Simonsen, JN; Wainberg, MA; Wamola, I, 1990)
"Chancroid is gaining importance as a sexually transmitted disease because of its association with transmission of human immunodeficiency virus type 1 (HIV-1)."	( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989)
"Chancroid is a major sexually transmitted disease in many developing countries."	( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987)
"The chancroid is the first cause of genital ulceration in the world."	( Boudghène-Stambouli, O; Merad-Boudia, A, 1997)
"Chancroid is a sexually transmitted infection associated with genital ulceration and lymphadenopathy caused by Haemophilus ducreyi."	( Campanella, S; Roberts, SA; Taylor, SL; Ussher, JE; Wilson, E, 2007)
"Chancroid is a genital ulcerative disease caused by Haemophilus ducreyi."	( Grillo-Ardila, CF; Huerfano, C; Romero, L, 2017)

Excerpt	Reference
"Chancroid has been shown to increase the risk of heterosexual transmission of HIV."	( Alfa, MJ; DeGagne, P, 1997)

Excerpt	Reference
"Since the treatment of chancroid was reviewed in 1982, the results of subsequent treatment trials have offered the clinician additional therapeutic choices as well as shorter courses of therapy."	( Schmid, GP, 1986)
"Although single-dose and short-course treatment of chancroid have been described, the increasing resistance of Hemophilus ducreyi to antimicrobial agents requires continuing evaluation of new therapies."	( D'Costa, LJ; Greenblatt, RM; Naamara, W; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1987)
"Thiamphenicol was used to treat 547 men with chancroid."	( Latif, AS, 1982)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	128 (54.24)	23.3326
1990's	65 (27.54)	12.5806
2000's	20 (8.47)	18.1394
2010's	22 (9.32)	28.8240
2020's	1 (0.42)	9.53

Drug	Relationship Strength	Studies	Trials
formaldehyde	low	1	0
nitrates	low	1	0
phosphorylethanolamine	low	1	0
benzothiazide	low	1	0
camphor, (+-)-isomer	low	1	0
ciprofloxacin	medium	17	8
dapsone	low	1	0
enoxacin	medium	2	1
fleroxacin	medium	4	2
gentamicin	low	6	0
metronidazole	low	1	0
norfloxacin	medium	1	1
prazosin	low	1	0
probenecid	low	3	0
sulfadiazine	low	4	0
sulfamerazine	low	2	0
sulfamethazine	low	2	0
sulfamethoxazole	medium	27	5
sulfanilamide	low	4	0
sulfaphenazole	medium	1	1
sulfathiazole	low	3	0
sulfisoxazole	medium	9	3
trimethoprim	medium	37	10
penicillin g	low	4	0
chloramphenicol	low	3	0
cephalothin	low	1	0
kanamycin a	low	4	0
carbostyril	low	2	0
cycloheximide	low	1	0
ampicillin	low	3	0
iodoform	low	1	0
thiophenes	low	1	0
dodecyl sulfate	low	2	0
quinazolines	low	1	0
podophyllotoxin	low	1	0
erythromycin stearate	medium	1	1
erythromycin	medium	34	8
sulfamoxole	medium	2	1
vancomycin	low	2	0
digoxigenin	low	1	0
spectinomycin	medium	1	1
sulfadoxine	low	1	0
fluorescein-5-isothiocyanate	low	1	0
streptomycin	medium	32	2
phosphoric acid, trisodium salt	low	1	0
thiamphenicol	medium	3	1
phosphotyrosine	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
azides	low	2	0
amoxicillin	medium	3	2
imiquimod	low	1	0
sulfamoxole, trimethoprim drug combination	medium	2	1
sulfametrole	medium	3	2
cephalosporin c	medium	6	1
fibrinogen	low	4	0
glycidyl nitrate	low	1	0
cp 65,526	low	1	0
beta-lactams	medium	1	1
trimerazine	low	2	0
cortisone	low	1	0
rosoxacin	low	1	0
trimethoprim, sulfamethoxazole drug combination	medium	20	7
povidone-iodine	low	1	0
n-acetylneuraminic acid	low	1	0
fibrin	low	1	0
inositol 3-phosphate	low	2	0
retinol	low	1	0
cocaine	low	1	0
mupirocin	low	1	0
zithromax	medium	15	3
sodium dodecyl sulfate	low	2	0
clavulanic acid	medium	2	2
cytochalasin b	low	2	0
hr 810	low	1	0
cefotaxime	low	1	0
i(3)so3-galactosylceramide	low	1	0
rosaramicin	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
lipid a	low	2	0
podophyllin	low	1	0
clove	low	2	0
nad	low	1	0
ropocamptide	low	1	0
ro13-9904	medium	16	4
interleukin-8	low	2	0
heme	low	1	0
ascorbic acid	low	1	0
tetracycline	medium	17	2
chlortetracycline	low	7	0
oxytetracycline, anhydrous	low	2	0
lymecycline	low	1	0
agar	low	3	0
g(m3) ganglioside	low	1	0
cytochalasin d	low	1	0
acyclovir	low	1	0
guanosine tetraphosphate	low	1	0
rifampin	medium	2	1
valacyclovir	low	1	0

Protein Targets (799)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
Chain A, Ferritin light chain	4	0	0	4
Thymidine kinase	0	1	0	1
thioredoxin reductase	8	0	0	8
phosphopantetheinyl transferase	9	0	0	9
GLS protein	7	0	0	7
TDP1 protein	25	0	0	25
Smad3	6	0	0	6
thyroid stimulating hormone receptor	15	0	0	15
EWS/FLI fusion protein	15	0	0	15
arylsulfatase A	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	17	0	0	17
activating transcription factor 6	8	0	0	8
Histone H2A.x	8	0	0	8
Bloom syndrome protein isoform 1	3	0	0	3
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lamin isoform A-delta10	17	0	0	17
Solute carrier family 22 member 1	0	2	0	4
ATP-binding cassette sub-family C member 3	0	23	0	23
Multidrug resistance-associated protein 4	0	23	0	23
Solute carrier family 22 member 6	0	4	0	5
Bile salt export pump	0	8	0	8
Bile salt export pump	0	32	0	32
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	9	0	9
Cytochrome P450 2J2	0	6	0	6
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	4	0	5
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	8
Canalicular multispecific organic anion transporter 1	0	22	0	22
Thymidine kinase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	12	0	0	12
Chain A, Beta-lactamase	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	6
Beta-lactamase	0	0	0	5
Beta-lactamase	0	1	0	6
AR protein	25	0	0	25
apical membrane antigen 1, AMA1	4	0	0	4
estrogen nuclear receptor alpha	33	0	0	33
Beta-lactamase	0	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	9	0	0	9
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
DNA polymerase kappa isoform 1	6	0	0	6
Beta-lactamase SHV-1	0	1	0	5
Beta-lactamase SHV-1	0	2	0	6
Beta-lactamase	0	1	0	5
Kappa-type opioid receptor	0	0	0	5
Solute carrier family 15 member 1	0	9	0	10
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	4
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	1	0	6
Beta-lactamase	0	1	0	5
Solute carrier family 15 member 2	0	7	0	7
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	4
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	6	0	0	6
Beta-lactamase	0	0	0	4
acid sphingomyelinase	2	0	0	2
GLI family zinc finger 3	21	0	0	21
retinoic acid nuclear receptor alpha variant 1	17	0	0	17
farnesoid X nuclear receptor	13	0	0	13
Beta-lactamase	0	2	0	6
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase type 2	0	0	0	4
Metallo-beta-lactamase VIM-11	0	0	0	5
Metallo-beta-lactamase VIM-2	0	0	0	5
Beta-lactamase	0	0	0	5
Metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	2	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
chromobox protein homolog 1	19	0	0	19
thyroid hormone receptor beta isoform 2	19	0	0	19
DNA polymerase beta	4	0	0	4
geminin	27	0	0	27
Carbonic anhydrase 1	0	9	0	10
Carbonic anhydrase 2	0	9	1	11
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	1
Spike glycoprotein	9	0	1	10
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	0	0	4
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	5	0	5
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	5	0	5
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	6
Histamine H3 receptor	0	0	0	3
Beta-lactamase class B VIM-2	0	0	0	5
Beta-lactamase VIM-1	0	0	0	4
ATP-dependent phosphofructokinase	4	0	0	4
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	7	0	0	7
RAR-related orphan receptor gamma	15	0	0	15
thioredoxin glutathione reductase	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
glucocorticoid receptor [Homo sapiens]	16	0	0	16
estrogen-related nuclear receptor alpha	20	0	0	20
vitamin D (1,25- dihydroxyvitamin D3) receptor	14	0	0	14
IDH1	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	19	0	0	19
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	10	0	0	10
Polyphenol oxidase 2	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	4	1	6
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Carbonic anhydrase 4	0	5	0	5
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase 15	0	3	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Luciferase	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	20	0	0	20
G	8	0	0	8
cytochrome P450 2D6	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	9	0	0	9
pyruvate kinase PKM isoform a	1	0	0	1
survival motor neuron protein isoform d	9	0	0	9
cytochrome P450 3A4 isoform 1	12	0	0	12
Gamma-aminobutyric acid receptor subunit pi	12	2	0	15
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Gamma-aminobutyric acid receptor subunit beta-1	12	2	0	15
Gamma-aminobutyric acid receptor subunit delta	12	2	0	15
Gamma-aminobutyric acid receptor subunit gamma-2	12	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-5	12	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-3	12	2	0	15
Gamma-aminobutyric acid receptor subunit gamma-1	12	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-2	12	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-4	12	2	0	15
Gamma-aminobutyric acid receptor subunit gamma-3	12	2	0	15
Gamma-aminobutyric acid receptor subunit alpha-6	12	2	0	15
Histamine H2 receptor	12	0	0	12
Gamma-aminobutyric acid receptor subunit alpha-1	12	2	0	15
Gamma-aminobutyric acid receptor subunit beta-3	12	2	0	15
Gamma-aminobutyric acid receptor subunit beta-2	12	2	0	15
GABA theta subunit	12	2	0	15
Inositol hexakisphosphate kinase 1	8	0	0	8
Gamma-aminobutyric acid receptor subunit epsilon	12	2	0	15
cytochrome P450 2C9, partial	8	0	0	8
ATAD5 protein, partial	6	0	0	6
67.9K protein	11	0	0	11
Nuclear receptor ROR-gamma	7	0	0	7
Chain A, serum paraoxonase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	6	0	0	6
Carbonic anhydrase 12	0	3	0	3
Carbonic anhydrase 3	0	2	0	2
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 6	0	4	0	4
Carbonic anhydrase 5A, mitochondrial	0	4	0	5
Carbonic anhydrase 7	0	2	0	2
Carbonic anhydrase 9	0	5	0	5
Carbonic anhydrase 13	0	2	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	3	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	1	0	4
Albumin	0	0	4	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase VIM-2	0	0	0	3
Solute carrier family 22 member 7	0	3	0	3
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
Solute carrier family 22 member 11	0	4	0	5
Solute carrier family 22 member 8	0	5	0	6
Solute carrier family 22 member 7	0	4	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
endonuclease IV	3	0	0	3
WRN	2	0	0	2
Microtubule-associated protein tau	9	0	0	10
vitamin D3 receptor isoform VDRA	10	0	0	10
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
heat shock protein beta-1	9	0	0	9
importin subunit beta-1 isoform 1	2	0	0	2
flap endonuclease 1	3	0	0	3
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	2	0	0	2
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Solute carrier family 22 member 8	0	3	0	4
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase OXA-1	0	1	0	2
Beta-lactamase TEM	0	3	0	6
Beta-lactamase	0	0	0	2
phosphoglycerate kinase	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
SMAD family member 2	6	0	0	6
USP1 protein, partial	12	0	0	12
SMAD family member 3	6	0	0	6
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	7	0	0	7
nuclear receptor subfamily 1, group I, member 3	14	0	0	14
progesterone receptor	10	0	0	10
retinoid X nuclear receptor alpha	19	0	0	19
peroxisome proliferator-activated receptor delta	13	0	0	13
peroxisome proliferator activated receptor gamma	12	0	0	12
caspase-3	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
thyrotropin-releasing hormone receptor	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	8	0	0	8
mitogen-activated protein kinase 1	7	0	0	7
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Cellular tumor antigen p53	15	0	0	15
Glutamate receptor 2	7	0	0	7
Caspase-2	0	0	1	1
Inositol monophosphatase 1	2	0	0	2
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
interleukin 8	13	0	0	13
pregnane X nuclear receptor	16	0	0	16
aryl hydrocarbon receptor	8	0	0	8
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
streptokinase A precursor	0	0	6	6
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
Cytochrome P450 3A4	0	7	0	7
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
50S ribosomal protein L36 2	0	4	1	5
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	8	0	8
Cytochrome P450 1A2	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	3	0	5
DNA gyrase subunit B	0	3	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
Cytochrome P450 2D6	0	2	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	3	0	3
Multidrug resistance protein MdtK	0	0	2	2
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Potassium voltage-gated channel subfamily H member 2	0	7	0	8
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Neutrophil elastase	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	5	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
D	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2B adrenergic receptor	0	3	1	4
Alpha-2C adrenergic receptor	0	3	1	4
Alpha-2A adrenergic receptor	0	3	1	4
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	0	2
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	5	0	5
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	4
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
D(2) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sodium-dependent dopamine transporter	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Leukotriene B4 receptor 1	1	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	1	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	3	0	3
dopamine D1 receptor	2	0	0	2
pregnane X receptor	4	0	0	4
regulator of G-protein signaling 4	2	0	0	2
peripheral myelin protein 22 isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
muscarinic acetylcholine receptor M1	3	0	0	3
Glucocorticoid receptor	0	3	0	3
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	6	0	0	6
Multidrug and toxin extrusion protein 1	0	3	0	3
glp-1 receptor, partial	6	0	0	6
Fumarate hydratase	5	0	0	5
PPM1D protein	3	0	0	3
polyprotein	5	0	0	5
P53	1	0	0	1
RPL19A	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
cellular tumor antigen p53 isoform a	3	0	0	3
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
ras-related protein Rab-9A	6	0	0	6
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Alpha-synuclein	1	3	0	4
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
PINK1	1	0	0	1
Parkin	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 3	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
muscleblind-like protein 1 isoform 1	3	0	0	3
Myeloperoxidase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
5-hydroxytryptamine receptor 6	0	1	0	1
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
PAX8	0	0	0	2
thyroid stimulating hormone receptor	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
V-type proton ATPase subunit B, brain isoform	0	1	0	1
RISC-loading complex subunit TARBP2	0	0	1	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
ATP-dependent translocase ABCB1	0	2	0	2
ATP-dependent translocase ABCB1	0	2	0	3
60 kDa chaperonin	0	2	0	2
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	4	0	4
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
alpha synuclein, partial	1	0	0	1
hypothetical protein, conserved	2	0	0	2
glucocerebrosidase	2	0	0	2
luciferase	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Caspase-7	1	0	0	1
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
huntingtin isoform 2	2	0	0	2
peripheral myelin protein 22	5	0	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Epidermal growth factor receptor	0	2	0	2
Integrin beta-3	2	0	0	2
Tyrosine-protein kinase Fyn	0	1	0	1
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Integrin alpha-IIb	2	0	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	5	0	6
Adenosine receptor A3	0	2	0	2
Muscarinic acetylcholine receptor M1	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	6	1	7
Alpha-2C adrenergic receptor	0	4	0	5
Muscarinic acetylcholine receptor M3	0	2	0	2
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
Acetylcholinesterase	0	2	0	2
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Histamine H2 receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	6	1	9
5-hydroxytryptamine receptor 2A	0	2	0	2
Adenosine receptor A2a	0	4	0	4
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	3	0	3
Kappa-type opioid receptor	0	2	0	2
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
Alpha-1A adrenergic receptor	0	6	1	7
Fatty-acid amide hydrolase 1	1	0	0	1
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Glutamate receptor ionotropic, kainate 5	1	0	0	1
histone acetyltransferase KAT2A isoform 1	6	0	0	6
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
15-lipoxygenase, partial	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Chain A, Isoleucyl-tRNA synthetase	0	1	0	1
heat shock protein 90	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	2
Isoleucine--tRNA ligase	0	1	0	1
Estrogen receptor	0	0	2	2
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	0	1	0	1
Estrogen receptor beta	0	0	2	2
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Sodium/iodide cotransporter	0	1	0	1
neuropeptide S receptor isoform A	2	0	0	2
Valosin-containing protein	0	1	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
transcriptional regulator ERG isoform 3	3	0	0	3
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Tyrosine-protein kinase Lck	0	0	0	1
Proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
alpha-galactosidase	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Prostaglandin G/H synthase 1	0	1	0	1
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Prostaglandin G/H synthase 2	0	1	0	1
Tubulin beta-3 chain	0	1	1	3
Tubulin beta-2A chain	0	1	1	3
Tubulin beta-8 chain	0	1	1	3
Calcium-activated potassium channel subunit alpha-1	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
interferon gamma precursor	0	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Beta-casein	0	1	0	1
Interstitial collagenase	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
D(4) dopamine receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	4	1	5
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	2	1	7
Alpha-1B adrenergic receptor	0	2	1	5
5-hydroxytryptamine receptor 2B	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Multidrug and toxin extrusion protein 2	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
Solute carrier organic anion transporter family member 1A4	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Aurora kinase A	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	3	0	3
exodeoxyribonuclease V subunit RecC	0	3	0	3
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	2	0	2
Endothelin-1 receptor	0	3	0	3
Protease	0	1	1	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Protein argonaute-2	0	0	1	1
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	1	0	0	1
cytochrome P450 2C19 precursor	3	0	0	3
Cytochrome P450 2C8	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	3	0	3
Protein arginine N-methyltransferase 6	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (236)

Protein Targets (799)

Chancroid

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (236)

Drugs Studied (110)

Protein Targets (799)