A drug used to treat or prevent skin disorders or for the routine care of skin.
| Member | Definition | Class |
|---|
| adapalene | A naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether. | adapalene |
| aminolevulinic acid | The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. | 5-aminolevulinic acid; 5-ammoniolevulinate |
| aminolevulinic acid hydrochloride | A hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. | 5-aminolevulinic acid hydrochloride |
| azelaic acid | An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups. | nonanedioic acid |
| chloroquine | An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | chloroquine |
| cyclosporine | A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. | cyclosporin A |
| fluticasone propionate | A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a propionyl substituent at position 17; has anti-inflammatory, anti-asthmatic and anti-allergic activity. | fluticasone propionate |
| hydrocortisone-17-butyrate | Cortisol esterified with butyric acid at the 17-hydroxy group. | cortisol 17-butyrate |
| hydroxychloroquine | An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. | hydroxychloroquine |
| hydroxyzine | A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively. | hydroxyzine |
| melanotan-1 | A polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria. | afamelanotide |
| methotrexate | | methotrexate |
| methoxsalen | A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. | methoxsalen |
| methyl 5-aminolevulinate | The methyl ester of 5-aminolevulinic acid. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application (often as the hydrochloride salt) results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. | methyl 5-aminolevulinate |
| methyl 5-aminolevulinate hydrochloride | The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. | methyl 5-aminolevulinate hydrochloride |
| monobenzone | The monobenzyl ether of hydroquinone. It is used as a topical drug for medical depigmentation. | monobenzone |
| msh, 4-nle-7-phe-alpha- | A polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria. | afamelanotide |
| oxybenzone | A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively. | oxybenzone |
| resorcinol monoacetate | A member of the class of phenols that is resorcinol in which one of the phenolic hydroxy groups has been converted into its acetate ester. It has keratolytic properties and has been used for the treatment of acne. | resorcinol monoacetate |
| sulfapyridine | A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position. | sulfapyridine |
| trioxsalen | 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis. | trioxsalen |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 19.8974 | 1 | 5 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 1.4863 | 2 | 8 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 52.0101 | 2 | 5 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 5.2338 | 1 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 29.1834 | 1 | 7 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 19.6222 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 15.7254 | 12 | 67 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 17.5305 | 2 | 13 |
| arylsulfatase A | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 12.3041 | 3 | 5 |
| Ataxin-2 | Homo sapiens (human) | Potency | 10.1718 | 2 | 5 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 18.1796 | 2 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 13.8536 | 2 | 6 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 22.6963 | 2 | 3 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 20.3699 | 1 | 4 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 4.2355 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 4.2355 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 8.6642 | 3 | 13 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.1000 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 18.7791 | 1 | 5 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 21.4514 | 2 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 21.1613 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 19.9470 | 2 | 6 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 17.3357 | 2 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 51.5577 | 2 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 87.2682 | 2 | 6 |
| ClpP | Bacillus subtilis | Potency | 23.7358 | 1 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 3.9065 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 17.9177 | 1 | 5 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 5.2898 | 1 | 4 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 8.8006 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 11.8501 | 2 | 13 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.0426 | 2 | 10 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 14.6166 | 1 | 10 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 73.5826 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 36.4690 | 1 | 3 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 4.6109 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 16.5300 | 12 | 90 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 19.7290 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 14.4934 | 9 | 68 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 13.0562 | 1 | 6 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 9.9733 | 4 | 22 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 12.3685 | 3 | 9 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 69.6219 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 17.9177 | 1 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 11.2881 | 1 | 7 |
| geminin | Homo sapiens (human) | Potency | 0.8246 | 2 | 9 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 14.5483 | 2 | 12 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 4.5903 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 5.7920 | 3 | 11 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 15.1418 | 1 | 8 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 1.2925 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 26.7776 | 2 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 25.9042 | 1 | 4 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 31.6802 | 2 | 5 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 33.9870 | 2 | 10 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 17.9177 | 1 | 5 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 20.1992 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 0.0052 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 17.9177 | 1 | 10 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.2375 | 3 | 10 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 7.6793 | 2 | 11 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 22.9289 | 3 | 10 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 21.8865 | 2 | 4 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 14.3148 | 1 | 3 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 60.2570 | 3 | 4 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.0028 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 2.4108 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 16.5703 | 4 | 19 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 4.8738 | 2 | 5 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 21.3138 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 25.4556 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 35.4813 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 1.5849 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 17.9208 | 3 | 38 |
| P53 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 37.0264 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 6.8475 | 2 | 6 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 95.2834 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 8.3066 | 5 | 14 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 17.4384 | 4 | 8 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 17.9707 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.5506 | 1 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 30.3001 | 1 | 2 |
| PPM1D protein | Homo sapiens (human) | Potency | 4.2501 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 30.1270 | 3 | 19 |
| progesterone receptor | Homo sapiens (human) | Potency | 12.4707 | 3 | 9 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 15.0267 | 2 | 27 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 17.4950 | 3 | 27 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.5904 | 4 | 18 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 27.5391 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 27.5391 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 112.2020 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 19.5559 | 1 | 4 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 6.0044 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 6.8118 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 7.4003 | 2 | 19 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 29.1020 | 3 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 9.7605 | 3 | 16 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 23.1380 | 5 | 11 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.5506 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.5506 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 138.3939 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 26.8325 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 19.9583 | 5 | 9 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 15.1418 | 1 | 8 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 3.6000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 0.0011 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.0500 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 2.3560 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.0146 | 2 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.2340 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 2.3560 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.2340 | 1 | 1 |
| 6-phosphogluconate dehydrogenase, decarboxylating | Homo sapiens (human) | Ki | 136.7000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 3.6000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 27.3800 | 2 | 2 |
| Adenosine deaminase | Homo sapiens (human) | Ki | 0.0160 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 1.3120 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 0.7370 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 3.8860 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 3.8540 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 9.3400 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1750 | 2 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 9.3400 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1750 | 2 | 2 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 4.7720 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 9.3400 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 2.3460 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.1750 | 2 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 5.4108 | 1 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 52.0332 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 12.9244 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 42.9705 | 2 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.9000 | 2 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 122.2115 | 2 | 2 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 6.2350 | 2 | 2 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | IC50 | 21.7900 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 92.6052 | 2 | 6 |
| ATP-binding cassette sub-family C member 3 | Rattus norvegicus (Norway rat) | Ki | 90.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 3.0464 | 41 | 42 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 2.7500 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 1.7183 | 6 | 6 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 3.5750 | 2 | 2 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 173.2333 | 3 | 3 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | IC50 | 0.0840 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 5.7614 | 29 | 39 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | IC50 | 0.1100 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Leishmania major | Ki | 0.0001 | 1 | 1 |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | IC50 | 10.0050 | 2 | 2 |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | Ki | 0.8800 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 190.4450 | 8 | 18 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 500.3000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | Ki | 0.3000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 24.6546 | 3 | 3 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Calcineurin subunit B type 1 | Homo sapiens (human) | IC50 | 34.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 69.1078 | 5 | 9 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | Ki | 11.2700 | 3 | 3 |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | Ki | 207.1920 | 5 | 5 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 14.7253 | 1 | 3 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 32.8520 | 1 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 14.7253 | 1 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 32.8520 | 1 | 4 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 32.8520 | 1 | 4 |
| Carbonic anhydrase 6 | Homo sapiens (human) | IC50 | 14.7253 | 1 | 3 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 32.8520 | 1 | 4 |
| Chain A, Diaminopimelate decarboxylase | Methanocaldococcus jannaschii | Ki | 89.0000 | 1 | 1 |
| Chain B, Diaminopimelate decarboxylase | Methanocaldococcus jannaschii | Ki | 89.0000 | 1 | 1 |
| Cyclic GMP-AMP synthase | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.1100 | 2 | 2 |
| Cystine/glutamate transporter | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | IC50 | 0.0012 | 2 | 5 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 50.0200 | 2 | 2 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Ki | 0.0400 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 0.9833 | 3 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 38.8000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 61.4358 | 5 | 6 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 6.0550 | 2 | 4 |
| Cytochrome P450 3A43 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A43 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A5 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| Cytochrome P450 3A7 | Homo sapiens (human) | IC50 | 2.0600 | 1 | 1 |
| Cytochrome P450 3A7 | Homo sapiens (human) | Ki | 7.6000 | 1 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.3780 | 1 | 1 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| Dihydrofolate reductase | Enterococcus faecium | IC50 | 0.0014 | 1 | 1 |
| Dihydrofolate reductase | Escherichia coli K-12 | IC50 | 4.1688 | 24 | 34 |
| Dihydrofolate reductase | Gallus gallus (chicken) | IC50 | 0.0545 | 2 | 2 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 1.5079 | 80 | 94 |
| Dihydrofolate reductase | Lacticaseibacillus casei | IC50 | 0.0138 | 29 | 30 |
| Dihydrofolate reductase | Mus musculus (house mouse) | IC50 | 0.0331 | 11 | 11 |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | IC50 | 0.0174 | 3 | 3 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 0.0717 | 12 | 13 |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | IC50 | 0.0047 | 10 | 11 |
| Dihydrofolate reductase | Escherichia coli K-12 | Ki | 34.5460 | 5 | 5 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 0.4019 | 11 | 11 |
| Dihydrofolate reductase | Lacticaseibacillus casei | Ki | 0.0000 | 1 | 1 |
| Dihydrofolate reductase | Mus musculus (house mouse) | Ki | 0.2167 | 17 | 18 |
| Dihydrofolate reductase | Pneumocystis carinii | Ki | 0.0000 | 1 | 1 |
| Dihydrofolate reductase | Staphylococcus aureus | Ki | 0.0005 | 2 | 2 |
| Dihydrofolate reductase | Bacillus anthracis | IC50 | 0.0136 | 1 | 2 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 611.0529 | 13 | 13 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| DNA ligase | Tequatrovirus T4 | IC50 | 823.0000 | 2 | 4 |
| DNA ligase 1 | Homo sapiens (human) | IC50 | 823.0000 | 2 | 4 |
| DNA ligase A | Mycobacterium tuberculosis H37Rv | IC50 | 823.0000 | 2 | 4 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | IC50 | 0.0800 | 1 | 1 |
| fMet-Leu-Phe receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Folate receptor alpha | Homo sapiens (human) | IC50 | 0.2262 | 4 | 4 |
| Folate receptor beta | Homo sapiens (human) | IC50 | 0.1585 | 4 | 4 |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | IC50 | 3.2000 | 1 | 1 |
| Folylpolyglutamate synthase, mitochondrial | Mus musculus (house mouse) | Ki | 166.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | IC50 | 12.9000 | 1 | 1 |
| Genome polyprotein | Zika virus | Ki | 92.3000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 0.0003 | 5 | 5 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0026 | 2 | 2 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Ki | 91.0000 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 67.6667 | 3 | 3 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 790.0000 | 1 | 1 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 790.0000 | 1 | 1 |
| Glutamate receptor 3 | Homo sapiens (human) | Ki | 790.0000 | 1 | 1 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 790.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 790.0000 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.0020 | 1 | 1 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | IC50 | 0.0014 | 1 | 1 |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 396,967.5905 | 13 | 13 |
| Hormone-sensitive lipase | Rattus norvegicus (Norway rat) | IC50 | 3.2500 | 1 | 1 |
| Ileal sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 24.0000 | 1 | 1 |
| Interleukin-2 | Mus musculus (house mouse) | IC50 | 0.0050 | 1 | 1 |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| Melanocortin receptor 3 | Homo sapiens (human) | IC50 | 0.0026 | 6 | 6 |
| Melanocortin receptor 3 | Mus musculus (house mouse) | IC50 | 0.0059 | 3 | 3 |
| Melanocortin receptor 3 | Homo sapiens (human) | Ki | 0.0007 | 2 | 2 |
| Melanocortin receptor 4 | Homo sapiens (human) | IC50 | 0.0032 | 14 | 14 |
| Melanocortin receptor 4 | Mus musculus (house mouse) | IC50 | 0.0022 | 4 | 4 |
| Melanocortin receptor 4 | Homo sapiens (human) | Ki | 0.0025 | 15 | 15 |
| Melanocortin receptor 5 | Homo sapiens (human) | IC50 | 0.0014 | 5 | 5 |
| Melanocortin receptor 5 | Mus musculus (house mouse) | IC50 | 0.1400 | 1 | 1 |
| Melanocortin receptor 5 | Homo sapiens (human) | Ki | 0.0052 | 2 | 2 |
| Melanocyte-stimulating hormone receptor | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| Melanocyte-stimulating hormone receptor | Mus musculus (house mouse) | IC50 | 0.0003 | 2 | 2 |
| Melanocyte-stimulating hormone receptor | Homo sapiens (human) | Ki | 0.0008 | 3 | 3 |
| Mineralocorticoid receptor | Homo sapiens (human) | IC50 | 0.1490 | 1 | 1 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 150.0000 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| Multidrug resistance associated protein | Homo sapiens (human) | Ki | 1,200.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 3.5082 | 10 | 10 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 127.1800 | 1 | 5 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 12.3042 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 2.9510 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 3.6183 | 2 | 3 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 4.0488 | 1 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 5.6249 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 20.9151 | 1 | 2 |
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | IC50 | 35.8790 | 2 | 2 |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | IC50 | 18.0450 | 2 | 2 |
| Peptidyl-prolyl cis-trans isomerase A | Homo sapiens (human) | IC50 | 0.0252 | 12 | 12 |
| Peptidyl-prolyl cis-trans isomerase A | Homo sapiens (human) | Ki | 0.0645 | 8 | 8 |
| Peptidyl-prolyl cis-trans isomerase B | Homo sapiens (human) | IC50 | 0.0088 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase D | Homo sapiens (human) | IC50 | 0.0036 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase D | Homo sapiens (human) | Ki | 0.0129 | 4 | 4 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | Homo sapiens (human) | Ki | 0.0060 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP4 | Homo sapiens (human) | IC50 | 0.0160 | 1 | 1 |
| Peptidylglycine alpha-amidating monooxygenase | Rattus norvegicus (Norway rat) | Ki | 0.0060 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Mus musculus (house mouse) | IC50 | 0.5700 | 1 | 1 |
| Phosphoethanolamine N-methyltransferase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 554.0000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 4.8920 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 2.5030 | 4 | 4 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 4.3914 | 2 | 3 |
| Procathepsin L | Homo sapiens (human) | IC50 | 5.4700 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 0.0210 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 1.0190 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 3.7260 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 2 |
| Proton-coupled folate transporter | Homo sapiens (human) | IC50 | 0.1208 | 2 | 2 |
| Pteridine reductase 1 | Leishmania major | Ki | 0.1095 | 2 | 2 |
| Reduced folate transporter | Homo sapiens (human) | IC50 | 0.0120 | 2 | 2 |
| Reduced folate transporter | Homo sapiens (human) | Ki | 3.5000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 722.9140 | 3 | 5 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 1,794.7350 | 2 | 2 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Ki | 1.1000 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | Ki | 0.0340 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Ki | 0.1300 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 0.4550 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 62.0000 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 0.1830 | 1 | 1 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.7506 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.1027 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 3.8860 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 3.8540 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 790.0000 | 1 | 1 |
| Solute carrier family 15 member 1 | Rattus norvegicus (Norway rat) | Ki | 2,200.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 230.0000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 599.7800 | 1 | 2 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 896.1255 | 1 | 2 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.9500 | 5 | 5 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.4845 | 4 | 4 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 1.2000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | Ki | 36.0000 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | IC50 | 3.5800 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 4.1390 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 1.3800 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Thymidylate synthase | Escherichia coli K-12 | IC50 | 11.4303 | 3 | 12 |
| Thymidylate synthase | Homo sapiens (human) | IC50 | 33.6082 | 12 | 21 |
| Thymidylate synthase | Lacticaseibacillus casei | IC50 | 158.1000 | 10 | 10 |
| Thymidylate synthase | Mus musculus (house mouse) | IC50 | 20.0000 | 2 | 2 |
| Thymidylate synthase | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Thymidylate synthase | Mus musculus (house mouse) | Ki | 45.0000 | 1 | 1 |
| Thymidylate synthase | Escherichia coli | IC50 | 60.6000 | 3 | 3 |
| Thymidylate synthase | Escherichia coli LF82 | IC50 | 18.0000 | 1 | 1 |
| Toll-like receptor 4 | Homo sapiens (human) | IC50 | 1.0400 | 1 | 1 |
| Toll-like receptor 7 | Homo sapiens (human) | IC50 | 3.4000 | 3 | 3 |
| Toll-like receptor 9 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 35.8790 | 2 | 2 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 5.4700 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | Ki | 0.0026 | 1 | 1 |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | IC50 | 10.0050 | 2 | 2 |
| Trifunctional purine biosynthetic protein adenosine-3 | Mus musculus (house mouse) | IC50 | 20.0000 | 2 | 2 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 211.8333 | 1 | 6 |