Page last updated: 2024-08-05 12:01:45
macrodiolide
A macropolylide which contains two ester linkages in one macrocyclic ring.
ChEBI ID: 145556
Members (6)
Member | Definition | Role |
---|---|---|
antimycin a | A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. | antimycin A |
boromycin | A boron-containing macrolide antibiotic that is isolated from Streptomyces antibioticus. | boromycin |
carpaine | An alkaloid that forms a major component of the papaya leaves and has been shown to exhibit cardiovascular effects. | carpaine |
elaiophylin | A macrodiolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes. | elaiophylin |
pateamine a | A marine macrodiolide that is isolated from the sponge Mycale hentscheli and exhibits anticancer and antiviral properties | pateamine |
riddelliine | A macrodiolide that is 13,19-didehydrosenecionan bearing two additional hydroxy substituents at positions 12 and 18 as well as two additional oxo groups at positions 11 and 16. | riddelliine |
Research
Studies (177)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 9 (5.08) | 18.7374 |
1990's | 9 (5.08) | 18.2507 |
2000's | 56 (31.64) | 29.6817 |
2010's | 71 (40.11) | 24.3611 |
2020's | 32 (18.08) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 11 (6.11%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 169 (93.89%) | 84.16% |