A macropolylide which contains two ester linkages in one macrocyclic ring.
| Member | Definition | Role |
|---|
| antimycin a | A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. | antimycin A |
| boromycin | A boron-containing macrolide antibiotic that is isolated from Streptomyces antibioticus. | boromycin |
| carpaine | An alkaloid that forms a major component of the papaya leaves and has been shown to exhibit cardiovascular effects. | carpaine |
| elaiophylin | A macrodiolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes. | elaiophylin |
| pateamine a | A marine macrodiolide that is isolated from the sponge Mycale hentscheli and exhibits anticancer and antiviral properties | pateamine |
| riddelliine | A macrodiolide that is 13,19-didehydrosenecionan bearing two additional hydroxy substituents at positions 12 and 18 as well as two additional oxo groups at positions 11 and 16. | riddelliine |