vitamin D

Any member of a group of fat-soluble hydroxy seco-steroids that exhibit biological activity against vitamin D deficiency. Vitamin D can be obtained from sun exposure, food and supplements and is biologically inactive and converted into the biologically active calcitriol via double hydroxylation in the body.

ChEBI ID: 27300

Members (12)

Member	Definition	Role
(1R,3S)-5-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylenecyclohexane-1,3-diol		(1R,3S)-5-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylenecyclohexane-1,3-diol
1,25-dihydroxy-24-oxo-16-ene-vitamin d3		1,25-Dihydroxy-24-oxo-16-ene-vitamin D3
1,25-dihydroxyergocalciferol	A hydroxycalciol that is vitamin D2 bearing additional hydroxy substituents at positions 1alpha and 25.	1alpha,25-dihydroxyvitamin D2
1,25-dihydroxyvitamin d3-26,23-lactone		1,25-Dihydroxyvitamin D3-26,23-lactone
24-hydroxyvitamin d2		24-hydroxyvitamin D2
25-hydroxyvitamin d 2	A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group.	25-hydroxyvitamin D2
carcinomedin		Carcinomedin
tei 9647		(23S)-1-hydroxy-25,27-didehydrovitamin D3 26,23-lactone
vitamin d 2	A vitamin D supplement and has been isolated from alfalfa.	vitamin D2
vitamin d3 sulfoconjugate		Vitamin D3 sulfoconjugate
zk 168281		ZK 168281
zk159222		ZK 159222

Research

Studies (3,671)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	1,681 (45.79)	18.7374
1990's	249 (6.78)	18.2507
2000's	494 (13.46)	29.6817
2010's	1,085 (29.56)	24.3611
2020's	162 (4.41)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	413 (9.47%)	5.53%
Reviews	340 (7.80%)	6.00%
Case Studies	214 (4.91%)	4.05%
Observational	28 (0.64%)	0.25%
Other	3,366 (77.18%)	84.16%